Drug Manufacturers - Specialty & Generic
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KMDA vs ADMA vs GRFS vs BIO vs BHVN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Drug Manufacturers - General
Medical - Devices
Biotechnology
KMDA vs ADMA vs GRFS vs BIO vs BHVN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Biotechnology | Drug Manufacturers - General | Medical - Devices | Biotechnology |
| Market Cap | $476M | $2.03B | $6.82B | $6.95B | $1.03B |
| Revenue (TTM) | $181M | $510M | $7.51B | $2.59B | $0.00 |
| Net Income (TTM) | $20M | $165M | $401M | $169M | $-648M |
| Gross Margin | 42.3% | 61.3% | 38.4% | 51.9% | — |
| Operating Margin | 14.5% | 42.1% | 17.0% | 9.2% | — |
| Forward P/E | 16.4x | 8.9x | 9.2x | 25.0x | — |
| Total Debt | $12M | $80M | $8.74B | $1.53B | $279M |
| Cash & Equiv. | $75M | $88M | $825M | $532M | $230M |
KMDA vs ADMA vs GRFS vs BIO vs BHVN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Sep 22 | May 26 | Return |
|---|---|---|---|
| Kamada Ltd. (KMDA) | 100 | 183.1 | +83.1% |
| ADMA Biologics, Inc. (ADMA) | 100 | 348.6 | +248.6% |
| Grifols, S.A. (GRFS) | 100 | 130.8 | +30.8% |
| Bio-Rad Laboratorie… (BIO) | 100 | 61.7 | -38.3% |
| Biohaven Ltd. (BHVN) | 100 | 154.5 | +54.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: KMDA vs ADMA vs GRFS vs BIO vs BHVN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
KMDA is the #2 pick in this set and the best alternative if growth exposure and long-term compounding is your priority.
- Rev growth 21.4%, EPS growth 48.0%, 3Y rev CAGR 14.7%
- 123.9% 10Y total return vs ADMA's 39.8%
- +25.0% vs ADMA's -64.1%
ADMA carries the broadest edge in this set and is the clearest fit for value and quality.
- Better valuation composite
- 32.4% margin vs BHVN's 3.2%
- 27.4% ROA vs BHVN's -138.0%, ROIC 36.0% vs -242.1%
GRFS ranks third and is worth considering specifically for income & stability and defensive.
- Dividend streak 2 yrs, beta 1.12, yield 2.6%
- Beta 1.12, yield 2.6%, current ratio 2.51x
- 2.6% yield, 2-year raise streak, vs KMDA's 2.6%, (3 stocks pay no dividend)
BIO is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 0.92, Low D/E 20.5%, current ratio 5.62x
- Beta 0.92 vs BHVN's 1.35, lower leverage
BHVN is the clearest fit if your priority is growth.
- 27.3% revenue growth vs GRFS's 0.2%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 27.3% revenue growth vs GRFS's 0.2% | |
| Value | Better valuation composite | |
| Quality / Margins | 32.4% margin vs BHVN's 3.2% | |
| Stability / Safety | Beta 0.92 vs BHVN's 1.35, lower leverage | |
| Dividends | 2.6% yield, 2-year raise streak, vs KMDA's 2.6%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +25.0% vs ADMA's -64.1% | |
| Efficiency (ROA) | 27.4% ROA vs BHVN's -138.0%, ROIC 36.0% vs -242.1% |
KMDA vs ADMA vs GRFS vs BIO vs BHVN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
KMDA vs ADMA vs GRFS vs BIO vs BHVN — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ADMA leads in 2 of 6 categories
GRFS leads 2 • KMDA leads 0 • BIO leads 0 • BHVN leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ADMA leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
GRFS and BHVN operate at a comparable scale, with $7.5B and $0 in trailing revenue. ADMA is the more profitable business, keeping 32.4% of every revenue dollar as net income compared to GRFS's 5.3%. On growth, KMDA holds the edge at +16.9% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $181M | $510M | $7.5B | $2.6B | $0 |
| EBITDAEarnings before interest/tax | $41M | $221M | $1.6B | -$315M | -$646M |
| Net IncomeAfter-tax profit | $20M | $165M | $401M | $169M | -$648M |
| Free Cash FlowCash after capex | $16M | $108M | $772M | $357M | -$594M |
| Gross MarginGross profit ÷ Revenue | +42.3% | +61.3% | +38.4% | +51.9% | — |
| Operating MarginEBIT ÷ Revenue | +14.5% | +42.1% | +17.0% | +9.2% | — |
| Net MarginNet income ÷ Revenue | +11.2% | +32.4% | +5.3% | +6.5% | — |
| FCF MarginFCF ÷ Revenue | +8.7% | +21.2% | +10.3% | +13.8% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | +16.9% | -0.3% | -0.6% | +1.1% | — |
| EPS Growth (YoY)Latest quarter vs prior year | -15.7% | +72.7% | +40.0% | -9.5% | +59.4% |
Valuation Metrics
GRFS leads this category, winning 4 of 6 comparable metrics.
Valuation Metrics
At 9.2x trailing earnings, BIO trades at a 59% valuation discount to KMDA's 22.3x P/E. On an enterprise value basis, GRFS's 8.5x EV/EBITDA is more attractive than BIO's 16.7x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $476M | $2.0B | $6.8B | $6.9B | $1.0B |
| Enterprise ValueMkt cap + debt − cash | $413M | $2.0B | $16.1B | $7.9B | $1.1B |
| Trailing P/EPrice ÷ TTM EPS | 22.32x | 14.12x | 12.03x | 9.23x | -1.42x |
| Forward P/EPrice ÷ next-FY EPS est. | 16.36x | 8.88x | 9.20x | 25.00x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | 9.26x | 10.15x | 8.47x | 16.70x | — |
| Price / SalesMarket cap ÷ Revenue | 2.44x | 3.98x | 0.80x | 2.69x | — |
| Price / BookPrice ÷ Book value/share | 1.79x | 4.35x | 0.61x | 0.94x | 20.12x |
| Price / FCFMarket cap ÷ FCF | 28.14x | 73.05x | 7.72x | 18.55x | — |
Profitability & Efficiency
ADMA leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
ADMA delivers a 39.0% return on equity — every $100 of shareholder capital generates $39 in annual profit, vs $-9 for BHVN. KMDA carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to BHVN's 5.36x. On the Piotroski fundamental quality scale (0–9), KMDA scores 6/9 vs BHVN's 2/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +7.8% | +39.0% | +5.2% | +2.4% | -8.7% |
| ROA (TTM)Return on assets | +5.4% | +27.4% | +2.0% | +2.2% | -138.0% |
| ROICReturn on invested capital | +10.7% | +36.0% | +5.4% | +2.6% | -2.4% |
| ROCEReturn on capital employed | +8.7% | +38.8% | +6.4% | +2.9% | -187.2% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 5 | 6 | 5 | 2 |
| Debt / EquityFinancial leverage | 0.04x | 0.17x | 1.15x | 0.21x | 5.36x |
| Net DebtTotal debt minus cash | -$64M | -$8M | $7.9B | $999M | $49M |
| Cash & Equiv.Liquid assets | $75M | $88M | $825M | $532M | $230M |
| Total DebtShort + long-term debt | $12M | $80M | $8.7B | $1.5B | $279M |
| Interest CoverageEBIT ÷ Interest expense | 26.41x | 50.85x | 2.05x | -2.49x | — |
Total Returns (Dividends Reinvested)
Evenly matched — KMDA and ADMA each lead in 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ADMA five years ago would be worth $48,678 today (with dividends reinvested), compared to $4,232 for BIO. Over the past 12 months, KMDA leads with a +25.0% total return vs ADMA's -64.1%. The 3-year compound annual growth rate (CAGR) favors ADMA at 34.3% vs BIO's -12.1% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +21.1% | -52.6% | -12.8% | -15.7% | -10.2% |
| 1-Year ReturnPast 12 months | +25.0% | -64.1% | +12.5% | +10.7% | -48.8% |
| 3-Year ReturnCumulative with dividends | +76.3% | +142.0% | +8.9% | -32.0% | -31.5% |
| 5-Year ReturnCumulative with dividends | +42.3% | +386.8% | -52.8% | -57.7% | +33.4% |
| 10-Year ReturnCumulative with dividends | +123.9% | +39.8% | -35.4% | +81.4% | +33.4% |
| CAGR (3Y)Annualised 3-year return | +20.8% | +34.3% | +2.9% | -12.1% | -11.8% |
Risk & Volatility
Evenly matched — KMDA and BIO each lead in 1 of 2 comparable metrics.
Risk & Volatility
BIO is the less volatile stock with a 0.92 beta — it tends to amplify market swings less than BHVN's 1.35 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KMDA currently trades 88.3% from its 52-week high vs ADMA's 35.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.17x | 1.22x | 1.12x | 0.92x | 1.35x |
| 52-Week HighHighest price in past year | $9.35 | $23.98 | $11.14 | $343.12 | $22.05 |
| 52-Week LowLowest price in past year | $6.50 | $7.21 | $7.09 | $211.43 | $7.48 |
| % of 52W HighCurrent price vs 52-week peak | +88.3% | +35.3% | +72.4% | +75.0% | +44.1% |
| RSI (14)Momentum oscillator 0–100 | 48.9 | 37.9 | 54.6 | 37.0 | 51.9 |
| Avg Volume (50D)Average daily shares traded | 59K | 7.3M | 714K | 306K | 2.0M |
Analyst Outlook
GRFS leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: KMDA as "Buy", ADMA as "Buy", GRFS as "Buy", BIO as "Buy", BHVN as "Buy". Consensus price targets imply 165.6% upside for ADMA (target: $23) vs 21.4% for BIO (target: $313). For income investors, GRFS offers the higher dividend yield at 2.63% vs KMDA's 2.59%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $12.00 | $22.50 | — | $312.50 | $21.29 |
| # AnalystsCovering analysts | 6 | 9 | 8 | 14 | 25 |
| Dividend YieldAnnual dividend ÷ price | +2.6% | — | +2.6% | — | — |
| Dividend StreakConsecutive years of raises | 1 | 1 | 2 | — | — |
| Dividend / ShareAnnual DPS | $0.21 | — | $0.18 | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +1.6% | +2.1% | +4.3% | 0.0% |
ADMA leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). GRFS leads in 2 (Valuation Metrics, Analyst Outlook). 2 tied.
KMDA vs ADMA vs GRFS vs BIO vs BHVN: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is KMDA or ADMA or GRFS or BIO or BHVN a better buy right now?
For growth investors, Kamada Ltd.
(KMDA) is the stronger pick with 21. 4% revenue growth year-over-year, versus 0. 2% for Grifols, S. A. (GRFS). Bio-Rad Laboratories, Inc. (BIO) offers the better valuation at 9. 2x trailing P/E (25. 0x forward), making it the more compelling value choice. Analysts rate Kamada Ltd. (KMDA) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — KMDA or ADMA or GRFS or BIO or BHVN?
On trailing P/E, Bio-Rad Laboratories, Inc.
(BIO) is the cheapest at 9. 2x versus Kamada Ltd. at 22. 3x. On forward P/E, ADMA Biologics, Inc. is actually cheaper at 8. 9x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — KMDA or ADMA or GRFS or BIO or BHVN?
Over the past 5 years, ADMA Biologics, Inc.
(ADMA) delivered a total return of +386. 8%, compared to -57. 7% for Bio-Rad Laboratories, Inc. (BIO). Over 10 years, the gap is even starker: KMDA returned +123. 9% versus GRFS's -35. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — KMDA or ADMA or GRFS or BIO or BHVN?
By beta (market sensitivity over 5 years), Bio-Rad Laboratories, Inc.
(BIO) is the lower-risk stock at 0. 92β versus Biohaven Ltd. 's 1. 35β — meaning BHVN is approximately 46% more volatile than BIO relative to the S&P 500. On balance sheet safety, Kamada Ltd. (KMDA) carries a lower debt/equity ratio of 4% versus 5% for Biohaven Ltd. — giving it more financial flexibility in a downturn.
05Which is growing faster — KMDA or ADMA or GRFS or BIO or BHVN?
By revenue growth (latest reported year), Kamada Ltd.
(KMDA) is pulling ahead at 21. 4% versus 0. 2% for Grifols, S. A. (GRFS). On earnings-per-share growth, the picture is similar: Grifols, S. A. grew EPS 147. 8% year-over-year, compared to -25. 9% for ADMA Biologics, Inc.. Over a 3-year CAGR, ADMA leads at 49. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — KMDA or ADMA or GRFS or BIO or BHVN?
Bio-Rad Laboratories, Inc.
(BIO) is the more profitable company, earning 29. 4% net margin versus 0. 0% for Biohaven Ltd. — meaning it keeps 29. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ADMA leads at 37. 5% versus 0. 0% for BHVN. At the gross margin level — before operating expenses — ADMA leads at 57. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is KMDA or ADMA or GRFS or BIO or BHVN more undervalued right now?
On forward earnings alone, ADMA Biologics, Inc.
(ADMA) trades at 8. 9x forward P/E versus 25. 0x for Bio-Rad Laboratories, Inc. — 16. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ADMA: 165. 6% to $22. 50.
08Which pays a better dividend — KMDA or ADMA or GRFS or BIO or BHVN?
In this comparison, GRFS (2.
6% yield), KMDA (2. 6% yield) pay a dividend. ADMA, BIO, BHVN do not pay a meaningful dividend and should not be held primarily for income.
09Is KMDA or ADMA or GRFS or BIO or BHVN better for a retirement portfolio?
For long-horizon retirement investors, Kamada Ltd.
(KMDA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 17), 2. 6% yield, +123. 9% 10Y return). Both have compounded well over 10 years (KMDA: +123. 9%, BHVN: +33. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between KMDA and ADMA and GRFS and BIO and BHVN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: KMDA is a small-cap high-growth stock; ADMA is a small-cap high-growth stock; GRFS is a small-cap deep-value stock; BIO is a small-cap deep-value stock; BHVN is a small-cap quality compounder stock. KMDA, GRFS pay a dividend while ADMA, BIO, BHVN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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