Biotechnology
Compare Stocks
5 / 10Stock Comparison
LEXX vs DBVT vs PRGO vs ALKS vs INVA
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Drug Manufacturers - Specialty & Generic
Biotechnology
Biotechnology
LEXX vs DBVT vs PRGO vs ALKS vs INVA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Drug Manufacturers - Specialty & Generic | Biotechnology | Biotechnology |
| Market Cap | $14M | $1712.35T | $1.61B | $5.90B | $1.93B |
| Revenue (TTM) | $522K | $0.00 | $4.18B | $1.56B | $424M |
| Net Income (TTM) | $-11M | $-168M | $-1.82B | $153M | $504M |
| Gross Margin | 84.9% | — | 34.2% | 65.4% | 76.2% |
| Operating Margin | -20.2% | — | -4.1% | 12.3% | 14.8% |
| Forward P/E | — | — | 5.6x | 24.8x | 11.9x |
| Total Debt | $109K | $22M | $3.97B | $70M | $269M |
| Cash & Equiv. | $2M | $194M | $532M | $1.12B | $551M |
LEXX vs DBVT vs PRGO vs ALKS vs INVA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jan 21 | May 26 | Return |
|---|---|---|---|
| Lexaria Bioscience … (LEXX) | 100 | 13.8 | -86.2% |
| DBV Technologies S.… (DBVT) | 100 | 38.9 | -61.1% |
| Perrigo Company plc (PRGO) | 100 | 27.4 | -72.6% |
| Alkermes plc (ALKS) | 100 | 168.7 | +68.7% |
| Innoviva, Inc. (INVA) | 100 | 189.8 | +89.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: LEXX vs DBVT vs PRGO vs ALKS vs INVA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
LEXX ranks third and is worth considering specifically for growth exposure.
- Rev growth 52.0%, EPS growth -40.4%, 3Y rev CAGR 40.3%
- 52.0% revenue growth vs DBVT's -100.0%
DBVT is the clearest fit if your priority is momentum.
- +110.4% vs PRGO's -51.2%
PRGO is the #2 pick in this set and the best alternative if income & stability is your priority.
- Dividend streak 10 yrs, beta 1.18, yield 9.8%
- Lower P/E (5.6x vs 24.8x)
- 9.8% yield; 10-year raise streak; the other 4 pay no meaningful dividend
Among these 5 stocks, ALKS doesn't own a clear edge in any measured category.
INVA carries the broadest edge in this set and is the clearest fit for long-term compounding and sleep-well-at-night.
- 94.9% 10Y total return vs ALKS's -11.0%
- Lower volatility, beta 0.13, Low D/E 22.9%, current ratio 14.64x
- Beta 0.13, current ratio 14.64x
- 118.9% margin vs LEXX's -20.7%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 52.0% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (5.6x vs 24.8x) | |
| Quality / Margins | 118.9% margin vs LEXX's -20.7% | |
| Stability / Safety | Beta 0.13 vs DBVT's 1.26 | |
| Dividends | 9.8% yield; 10-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +110.4% vs PRGO's -51.2% | |
| Efficiency (ROA) | 32.4% ROA vs LEXX's -178.4%, ROIC 14.2% vs -7.9% |
LEXX vs DBVT vs PRGO vs ALKS vs INVA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
LEXX vs DBVT vs PRGO vs ALKS vs INVA — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
INVA leads in 2 of 6 categories
PRGO leads 2 • ALKS leads 1 • LEXX leads 0 • DBVT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
INVA leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
PRGO and DBVT operate at a comparable scale, with $4.2B and $0 in trailing revenue. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to LEXX's -20.7%. On growth, ALKS holds the edge at +28.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $522,000 | $0 | $4.2B | $1.6B | $424M |
| EBITDAEarnings before interest/tax | -$10M | -$112M | $58M | $212M | $86M |
| Net IncomeAfter-tax profit | -$11M | -$168M | -$1.8B | $153M | $504M |
| Free Cash FlowCash after capex | -$9M | -$151M | $108M | $392M | $181M |
| Gross MarginGross profit ÷ Revenue | +84.9% | — | +34.2% | +65.4% | +76.2% |
| Operating MarginEBIT ÷ Revenue | -20.2% | — | -4.1% | +12.3% | +14.8% |
| Net MarginNet income ÷ Revenue | -20.7% | — | -43.5% | +9.8% | +118.9% |
| FCF MarginFCF ÷ Revenue | -16.7% | — | +2.6% | +25.1% | +42.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | -100.0% | — | -7.2% | +28.2% | +10.6% |
| EPS Growth (YoY)Latest quarter vs prior year | +53.4% | +91.5% | -56.4% | -4.1% | +4.0% |
Valuation Metrics
PRGO leads this category, winning 5 of 6 comparable metrics.
Valuation Metrics
At 6.9x trailing earnings, INVA trades at a 72% valuation discount to ALKS's 24.8x P/E. On an enterprise value basis, PRGO's 7.4x EV/EBITDA is more attractive than ALKS's 17.3x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $14M | $1712.35T | $1.6B | $5.9B | $1.9B |
| Enterprise ValueMkt cap + debt − cash | $13M | $1712.35T | $5.1B | $4.9B | $1.7B |
| Trailing P/EPrice ÷ TTM EPS | -0.97x | -0.76x | -1.14x | 24.76x | 6.91x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 5.56x | — | 11.91x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | 0.67x |
| EV / EBITDAEnterprise value multiple | — | — | 7.42x | 17.25x | 8.10x |
| Price / SalesMarket cap ÷ Revenue | 20.17x | — | 0.38x | 4.00x | 4.55x |
| Price / BookPrice ÷ Book value/share | 4.43x | 0.66x | 0.55x | 3.28x | 1.65x |
| Price / FCFMarket cap ÷ FCF | — | — | 11.12x | 12.28x | 9.88x |
Profitability & Efficiency
ALKS leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
INVA delivers a 46.5% return on equity — every $100 of shareholder capital generates $46 in annual profit, vs $-2 for LEXX. ALKS carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRGO's 1.35x. On the Piotroski fundamental quality scale (0–9), ALKS scores 7/9 vs LEXX's 3/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -2.4% | -130.2% | -50.7% | +8.8% | +46.5% |
| ROA (TTM)Return on assets | -178.4% | -89.0% | -19.8% | +5.4% | +32.4% |
| ROICReturn on invested capital | -7.9% | — | +3.7% | +18.9% | +14.2% |
| ROCEReturn on capital employed | -2.2% | -145.7% | +4.3% | +14.2% | +12.4% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 | 4 | 7 | 5 |
| Debt / EquityFinancial leverage | 0.04x | 0.13x | 1.35x | 0.04x | 0.23x |
| Net DebtTotal debt minus cash | -$2M | -$172M | $3.4B | -$1.0B | -$282M |
| Cash & Equiv.Liquid assets | $2M | $194M | $532M | $1.1B | $551M |
| Total DebtShort + long-term debt | $109,320 | $22M | $4.0B | $70M | $269M |
| Interest CoverageEBIT ÷ Interest expense | — | -189.82x | -7.20x | 32.30x | 63.45x |
Total Returns (Dividends Reinvested)
INVA leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in INVA five years ago would be worth $19,437 today (with dividends reinvested), compared to $1,023 for LEXX. Over the past 12 months, DBVT leads with a +110.4% total return vs PRGO's -51.2%. The 3-year compound annual growth rate (CAGR) favors INVA at 25.0% vs PRGO's -25.2% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -2.0% | +4.9% | -13.5% | +25.3% | +14.7% |
| 1-Year ReturnPast 12 months | -38.4% | +110.4% | -51.2% | +16.5% | +21.7% |
| 3-Year ReturnCumulative with dividends | -37.2% | +19.7% | -58.1% | +14.5% | +95.2% |
| 5-Year ReturnCumulative with dividends | -89.8% | -69.1% | -60.1% | +60.9% | +94.4% |
| 10-Year ReturnCumulative with dividends | -85.7% | -87.0% | -77.7% | -11.0% | +94.9% |
| CAGR (3Y)Annualised 3-year return | -14.4% | +6.2% | -25.2% | +4.6% | +25.0% |
Risk & Volatility
Evenly matched — ALKS and INVA each lead in 1 of 2 comparable metrics.
Risk & Volatility
INVA is the less volatile stock with a 0.13 beta — it tends to amplify market swings less than DBVT's 1.26 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALKS currently trades 96.7% from its 52-week high vs PRGO's 41.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.00x | 1.26x | 1.18x | 1.06x | 0.13x |
| 52-Week HighHighest price in past year | $1.55 | $26.18 | $28.44 | $36.60 | $25.15 |
| 52-Week LowLowest price in past year | $0.46 | $7.53 | $9.23 | $25.17 | $16.52 |
| % of 52W HighCurrent price vs 52-week peak | +41.3% | +76.3% | +41.2% | +96.7% | +90.7% |
| RSI (14)Momentum oscillator 0–100 | 36.1 | 48.1 | 60.9 | 60.2 | 39.9 |
| Avg Volume (50D)Average daily shares traded | 180K | 252K | 3.4M | 2.3M | 621K |
Analyst Outlook
PRGO leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: DBVT as "Buy", PRGO as "Hold", ALKS as "Buy", INVA as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 24.3% for ALKS (target: $44). PRGO is the only dividend payer here at 9.81% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | — | $46.33 | $20.00 | $44.00 | $37.67 |
| # AnalystsCovering analysts | — | 15 | 36 | 28 | 10 |
| Dividend YieldAnnual dividend ÷ price | — | — | +9.8% | — | — |
| Dividend StreakConsecutive years of raises | — | 0 | 10 | 0 | 0 |
| Dividend / ShareAnnual DPS | — | — | $1.15 | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | +0.5% | +0.2% |
INVA leads in 2 of 6 categories (Income & Cash Flow, Total Returns). PRGO leads in 2 (Valuation Metrics, Analyst Outlook). 1 tied.
LEXX vs DBVT vs PRGO vs ALKS vs INVA: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is LEXX or DBVT or PRGO or ALKS or INVA a better buy right now?
For growth investors, Lexaria Bioscience Corp.
(LEXX) is the stronger pick with 52. 0% revenue growth year-over-year, versus -5. 2% for Alkermes plc (ALKS). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (11. 9x forward), making it the more compelling value choice. Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — LEXX or DBVT or PRGO or ALKS or INVA?
On trailing P/E, Innoviva, Inc.
(INVA) is the cheapest at 6. 9x versus Alkermes plc at 24. 8x. On forward P/E, Perrigo Company plc is actually cheaper at 5. 6x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — LEXX or DBVT or PRGO or ALKS or INVA?
Over the past 5 years, Innoviva, Inc.
(INVA) delivered a total return of +94. 4%, compared to -89. 8% for Lexaria Bioscience Corp. (LEXX). Over 10 years, the gap is even starker: INVA returned +94. 9% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — LEXX or DBVT or PRGO or ALKS or INVA?
By beta (market sensitivity over 5 years), Innoviva, Inc.
(INVA) is the lower-risk stock at 0. 13β versus DBV Technologies S. A. 's 1. 26β — meaning DBVT is approximately 897% more volatile than INVA relative to the S&P 500. On balance sheet safety, Alkermes plc (ALKS) carries a lower debt/equity ratio of 4% versus 135% for Perrigo Company plc — giving it more financial flexibility in a downturn.
05Which is growing faster — LEXX or DBVT or PRGO or ALKS or INVA?
By revenue growth (latest reported year), Lexaria Bioscience Corp.
(LEXX) is pulling ahead at 52. 0% versus -5. 2% for Alkermes plc (ALKS). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, LEXX leads at 40. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — LEXX or DBVT or PRGO or ALKS or INVA?
Innoviva, Inc.
(INVA) is the more profitable company, earning 63. 8% net margin versus -1686. 0% for Lexaria Bioscience Corp. — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -1648. 0% for LEXX. At the gross margin level — before operating expenses — ALKS leads at 86. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is LEXX or DBVT or PRGO or ALKS or INVA more undervalued right now?
On forward earnings alone, Perrigo Company plc (PRGO) trades at 5.
6x forward P/E versus 11. 9x for Innoviva, Inc. — 6. 4x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 131. 8% to $46. 33.
08Which pays a better dividend — LEXX or DBVT or PRGO or ALKS or INVA?
In this comparison, PRGO (9.
8% yield) pays a dividend. LEXX, DBVT, ALKS, INVA do not pay a meaningful dividend and should not be held primarily for income.
09Is LEXX or DBVT or PRGO or ALKS or INVA better for a retirement portfolio?
For long-horizon retirement investors, Innoviva, Inc.
(INVA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 13)). Both have compounded well over 10 years (INVA: +94. 9%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between LEXX and DBVT and PRGO and ALKS and INVA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: LEXX is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; PRGO is a small-cap income-oriented stock; ALKS is a small-cap quality compounder stock; INVA is a small-cap high-growth stock. PRGO pays a dividend while LEXX, DBVT, ALKS, INVA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform all of them.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.