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Stock Comparison

LGVN vs NKTR

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
LGVN
Longeveron Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$20M
5Y Perf.-98.9%
NKTR
Nektar Therapeutics

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.67B
5Y Perf.-75.0%

LGVN vs NKTR — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
LGVN logoLGVN
NKTR logoNKTR
IndustryBiotechnologyBiotechnology
Market Cap$20M$1.67B
Revenue (TTM)$1M$63M
Net Income (TTM)$-23M$-121M
Gross Margin43.7%86.9%
Operating Margin-19.4%-156.5%
Total Debt$824K$86M
Cash & Equiv.$5M$15M

LGVN vs NKTRLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

LGVN
NKTR
StockFeb 21May 26Return
Longeveron Inc. (LGVN)1001.1-98.9%
Nektar Therapeutics (NKTR)10025.0-75.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: LGVN vs NKTR

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: NKTR leads in 4 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Longeveron Inc. is the stronger pick specifically for capital preservation and lower volatility. As sector peers, any of these can serve as alternatives in the same allocation.
LGVN
Longeveron Inc.
The Income Pick

LGVN is the clearest fit if your priority is income & stability and sleep-well-at-night.

  • Dividend streak 1 yrs, beta 0.95
  • Lower volatility, beta 0.95, Low D/E 14.5%, current ratio 1.33x
  • Beta 0.95, current ratio 1.33x
Best for: income & stability and sleep-well-at-night
NKTR
Nektar Therapeutics
The Growth Play

NKTR carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.

  • Rev growth -43.9%, EPS growth -12.1%, 3Y rev CAGR -15.7%
  • -57.6% 10Y total return vs LGVN's -98.8%
  • -43.9% revenue growth vs LGVN's -49.9%
Best for: growth exposure and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthNKTR logoNKTR-43.9% revenue growth vs LGVN's -49.9%
Quality / MarginsNKTR logoNKTR-192.9% margin vs LGVN's -18.9%
Stability / SafetyLGVN logoLGVNBeta 0.95 vs NKTR's 1.85, lower leverage
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)NKTR logoNKTR+7.8% vs LGVN's -40.1%
Efficiency (ROA)NKTR logoNKTR-45.2% ROA vs LGVN's -143.2%, ROIC -75.2% vs -5.9%

LGVN vs NKTR — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

LGVNLongeveron Inc.

Segment breakdown not available.

NKTRNektar Therapeutics
FY 2025
Non Cash Royalty Revenue Related To Sale Of Future Royalties
99.5%$55M
License Collaboration And Other Revenue
0.5%$300,000

LGVN vs NKTR — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLLGVNLAGGINGNKTR

Income & Cash Flow (Last 12 Months)

NKTR leads this category, winning 5 of 6 comparable metrics.

NKTR is the larger business by revenue, generating $63M annually — 52.2x LGVN's $1M. Profitability is closely matched — net margins range from -192.9% (NKTR) to -18.9% (LGVN). On growth, LGVN holds the edge at -39.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricLGVN logoLGVNLongeveron Inc.NKTR logoNKTRNektar Therapeuti…
RevenueTrailing 12 months$1M$63M
EBITDAEarnings before interest/tax-$22M-$97M
Net IncomeAfter-tax profit-$23M-$121M
Free Cash FlowCash after capex-$19M-$190M
Gross MarginGross profit ÷ Revenue+43.7%+86.9%
Operating MarginEBIT ÷ Revenue-19.4%-156.5%
Net MarginNet income ÷ Revenue-18.9%-192.9%
FCF MarginFCF ÷ Revenue-15.9%-3.0%
Rev. Growth (YoY)Latest quarter vs prior year-39.5%-51.1%
EPS Growth (YoY)Latest quarter vs prior year+11.1%+29.7%
NKTR leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

LGVN leads this category, winning 2 of 3 comparable metrics.
MetricLGVN logoLGVNLongeveron Inc.NKTR logoNKTRNektar Therapeuti…
Market CapShares × price$20M$1.7B
Enterprise ValueMkt cap + debt − cash$17M$1.7B
Trailing P/EPrice ÷ TTM EPS-0.68x-8.75x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue16.99x30.28x
Price / BookPrice ÷ Book value/share2.71x15.98x
Price / FCFMarket cap ÷ FCF
LGVN leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

LGVN leads this category, winning 4 of 7 comparable metrics.

LGVN delivers a -199.8% return on equity — every $100 of shareholder capital generates $-200 in annual profit, vs $-4 for NKTR. LGVN carries lower financial leverage with a 0.15x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 0.95x.

MetricLGVN logoLGVNLongeveron Inc.NKTR logoNKTRNektar Therapeuti…
ROE (TTM)Return on equity-199.8%-3.6%
ROA (TTM)Return on assets-143.2%-45.2%
ROICReturn on invested capital-5.9%-75.2%
ROCEReturn on capital employed-159.8%-59.7%
Piotroski ScoreFundamental quality 0–922
Debt / EquityFinancial leverage0.15x0.95x
Net DebtTotal debt minus cash-$4M$71M
Cash & Equiv.Liquid assets$5M$15M
Total DebtShort + long-term debt$824,000$86M
Interest CoverageEBIT ÷ Interest expense-3.30x
LGVN leads this category, winning 4 of 7 comparable metrics.

Total Returns (Dividends Reinvested)

NKTR leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in NKTR five years ago would be worth $3,063 today (with dividends reinvested), compared to $161 for LGVN. Over the past 12 months, NKTR leads with a +783.6% total return vs LGVN's -40.1%. The 3-year compound annual growth rate (CAGR) favors NKTR at 94.6% vs LGVN's -69.8% — a key indicator of consistent wealth creation.

MetricLGVN logoLGVNLongeveron Inc.NKTR logoNKTRNektar Therapeuti…
YTD ReturnYear-to-date+47.4%+96.0%
1-Year ReturnPast 12 months-40.1%+783.6%
3-Year ReturnCumulative with dividends-97.2%+636.7%
5-Year ReturnCumulative with dividends-98.4%-69.4%
10-Year ReturnCumulative with dividends-98.8%-57.6%
CAGR (3Y)Annualised 3-year return-69.8%+94.6%
NKTR leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

Evenly matched — LGVN and NKTR each lead in 1 of 2 comparable metrics.

LGVN is the less volatile stock with a 0.95 beta — it tends to amplify market swings less than NKTR's 1.85 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NKTR currently trades 78.1% from its 52-week high vs LGVN's 48.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricLGVN logoLGVNLongeveron Inc.NKTR logoNKTRNektar Therapeuti…
Beta (5Y)Sensitivity to S&P 5000.95x1.85x
52-Week HighHighest price in past year$1.80$109.00
52-Week LowLowest price in past year$0.47$7.99
% of 52W HighCurrent price vs 52-week peak+48.6%+78.1%
RSI (14)Momentum oscillator 0–10038.452.0
Avg Volume (50D)Average daily shares traded6.8M995K
Evenly matched — LGVN and NKTR each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.
MetricLGVN logoLGVNLongeveron Inc.NKTR logoNKTRNektar Therapeuti…
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target$132.83
# AnalystsCovering analysts33
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

NKTR leads in 2 of 6 categories (Income & Cash Flow, Total Returns). LGVN leads in 2 (Valuation Metrics, Profitability & Efficiency). 1 tied.

Best OverallLongeveron Inc. (LGVN)Leads 2 of 6 categories
Loading custom metrics...

LGVN vs NKTR: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is LGVN or NKTR a better buy right now?

For growth investors, Nektar Therapeutics (NKTR) is the stronger pick with -43.

9% revenue growth year-over-year, versus -49. 9% for Longeveron Inc. (LGVN). Analysts rate Nektar Therapeutics (NKTR) a "Buy" — based on 33 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — LGVN or NKTR?

Over the past 5 years, Nektar Therapeutics (NKTR) delivered a total return of -69.

4%, compared to -98. 4% for Longeveron Inc. (LGVN). Over 10 years, the gap is even starker: NKTR returned -57. 6% versus LGVN's -98. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — LGVN or NKTR?

By beta (market sensitivity over 5 years), Longeveron Inc.

(LGVN) is the lower-risk stock at 0. 95β versus Nektar Therapeutics's 1. 85β — meaning NKTR is approximately 94% more volatile than LGVN relative to the S&P 500. On balance sheet safety, Longeveron Inc. (LGVN) carries a lower debt/equity ratio of 15% versus 95% for Nektar Therapeutics — giving it more financial flexibility in a downturn.

04

Which is growing faster — LGVN or NKTR?

By revenue growth (latest reported year), Nektar Therapeutics (NKTR) is pulling ahead at -43.

9% versus -49. 9% for Longeveron Inc. (LGVN). On earnings-per-share growth, the picture is similar: Nektar Therapeutics grew EPS -12. 1% year-over-year, compared to -20. 6% for Longeveron Inc.. Over a 3-year CAGR, LGVN leads at -0. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — LGVN or NKTR?

Nektar Therapeutics (NKTR) is the more profitable company, earning -297.

1% net margin versus -1893. 6% for Longeveron Inc. — meaning it keeps -297. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NKTR leads at -253. 7% versus -1942. 2% for LGVN. At the gross margin level — before operating expenses — NKTR leads at 86. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — LGVN or NKTR?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is LGVN or NKTR better for a retirement portfolio?

For long-horizon retirement investors, Longeveron Inc.

(LGVN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 95)). Nektar Therapeutics (NKTR) carries a higher beta of 1. 85 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (LGVN: -98. 8%, NKTR: -57. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between LGVN and NKTR?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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LGVN

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 26%
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NKTR

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 52%
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Revenue Growth>
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(LGVN: -39.5% · NKTR: -51.1%)

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