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Stock Comparison

LPCN vs ANIP vs PRGO vs AMRX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
LPCN
Lipocine Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$13M
5Y Perf.-84.6%
ANIP
ANI Pharmaceuticals, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$1.78B
5Y Perf.+170.2%
PRGO
Perrigo Company plc

Drug Manufacturers - Specialty & Generic

HealthcareNYSE • IE
Market Cap$1.61B
5Y Perf.-78.6%
AMRX
Amneal Pharmaceuticals, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$4.31B
5Y Perf.+181.7%

LPCN vs ANIP vs PRGO vs AMRX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
LPCN logoLPCN
ANIP logoANIP
PRGO logoPRGO
AMRX logoAMRX
IndustryBiotechnologyDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & Generic
Market Cap$13M$1.78B$1.61B$4.31B
Revenue (TTM)$2M$883M$4.18B$3.02B
Net Income (TTM)$-11M$78M$-1.82B$72M
Gross Margin-13.4%69.1%34.2%36.9%
Operating Margin-413.6%12.6%-4.1%-0.2%
Forward P/E9.2x5.6x13.8x
Total Debt$0.00$325M$3.97B$124M
Cash & Equiv.$5M$286M$532M$282M

LPCN vs ANIP vs PRGO vs AMRXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

LPCN
ANIP
PRGO
AMRX
StockMay 20May 26Return
Lipocine Inc. (LPCN)10015.4-84.6%
ANI Pharmaceuticals… (ANIP)100270.2+170.2%
Perrigo Company plc (PRGO)10021.4-78.6%
Amneal Pharmaceutic… (AMRX)100281.7+181.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: LPCN vs ANIP vs PRGO vs AMRX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ANIP leads in 4 of 7 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Perrigo Company plc is the stronger pick specifically for valuation and capital efficiency and dividend income and shareholder returns. AMRX also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
LPCN
Lipocine Inc.
The Secondary Option

LPCN lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
ANIP
ANI Pharmaceuticals, Inc.
The Growth Play

ANIP carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.

  • Rev growth 43.8%, EPS growth 419.2%, 3Y rev CAGR 40.8%
  • 84.7% 10Y total return vs AMRX's -54.9%
  • Lower volatility, beta 0.63, Low D/E 60.1%, current ratio 2.71x
  • Beta 0.63, yield 0.1%, current ratio 2.71x
Best for: growth exposure and long-term compounding
PRGO
Perrigo Company plc
The Income Pick

PRGO is the #2 pick in this set and the best alternative if income & stability is your priority.

  • Dividend streak 10 yrs, beta 1.18, yield 9.8%
  • Lower P/E (5.6x vs 13.8x)
  • 9.8% yield, 10-year raise streak, vs ANIP's 0.1%, (2 stocks pay no dividend)
Best for: income & stability
AMRX
Amneal Pharmaceuticals, Inc.
The Momentum Pick

AMRX is the clearest fit if your priority is momentum.

  • +90.0% vs PRGO's -51.2%
Best for: momentum
See the full category breakdown
CategoryWinnerWhy
GrowthANIP logoANIP43.8% revenue growth vs LPCN's -82.3%
ValuePRGO logoPRGOLower P/E (5.6x vs 13.8x)
Quality / MarginsANIP logoANIP8.9% margin vs LPCN's -5.7%
Stability / SafetyANIP logoANIPBeta 0.63 vs PRGO's 1.18, lower leverage
DividendsPRGO logoPRGO9.8% yield, 10-year raise streak, vs ANIP's 0.1%, (2 stocks pay no dividend)
Momentum (1Y)AMRX logoAMRX+90.0% vs PRGO's -51.2%
Efficiency (ROA)ANIP logoANIP5.4% ROA vs LPCN's -59.4%, ROIC 11.2% vs -64.7%

LPCN vs ANIP vs PRGO vs AMRX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

LPCNLipocine Inc.
FY 2024
Royalty
100.0%$298,144
ANIPANI Pharmaceuticals, Inc.
FY 2024
Total Sales of Generics and Other
52.1%$320M
Sales of rare disease pharmaceutical products
37.4%$230M
Sales of Established Brands
10.5%$65M
PRGOPerrigo Company plc
FY 2025
Consumer Self-Care Americas
60.8%$2.6B
Consumer Self-Care International
39.2%$1.7B
AMRXAmneal Pharmaceuticals, Inc.
FY 2024
Specialty Segment
100.0%$446M

LPCN vs ANIP vs PRGO vs AMRX — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLPRGOLAGGINGLPCN

Income & Cash Flow (Last 12 Months)

ANIP leads this category, winning 6 of 6 comparable metrics.

PRGO is the larger business by revenue, generating $4.2B annually — 2086.9x LPCN's $2M. ANIP is the more profitable business, keeping 8.9% of every revenue dollar as net income compared to LPCN's -5.7%. On growth, ANIP holds the edge at +29.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricLPCN logoLPCNLipocine Inc.ANIP logoANIPANI Pharmaceutica…PRGO logoPRGOPerrigo Company p…AMRX logoAMRXAmneal Pharmaceut…
RevenueTrailing 12 months$2M$883M$4.2B$3.0B
EBITDAEarnings before interest/tax-$8M$203M$58M$169M
Net IncomeAfter-tax profit-$11M$78M-$1.8B$72M
Free Cash FlowCash after capex-$8M$128M$108M$150M
Gross MarginGross profit ÷ Revenue-13.4%+69.1%+34.2%+36.9%
Operating MarginEBIT ÷ Revenue-4.1%+12.6%-4.1%-0.2%
Net MarginNet income ÷ Revenue-5.7%+8.9%-43.5%+2.4%
FCF MarginFCF ÷ Revenue-3.9%+14.5%+2.6%+5.0%
Rev. Growth (YoY)Latest quarter vs prior year+27.2%+29.6%-7.2%+11.5%
EPS Growth (YoY)Latest quarter vs prior year-54.3%+3.1%-56.4%+2.1%
ANIP leads this category, winning 6 of 6 comparable metrics.

Valuation Metrics

PRGO leads this category, winning 4 of 6 comparable metrics.

At 25.3x trailing earnings, ANIP trades at a 59% valuation discount to AMRX's 62.4x P/E. On an enterprise value basis, PRGO's 7.4x EV/EBITDA is more attractive than ANIP's 9.0x.

MetricLPCN logoLPCNLipocine Inc.ANIP logoANIPANI Pharmaceutica…PRGO logoPRGOPerrigo Company p…AMRX logoAMRXAmneal Pharmaceut…
Market CapShares × price$13M$1.8B$1.6B$4.3B
Enterprise ValueMkt cap + debt − cash$8M$1.8B$5.1B$4.2B
Trailing P/EPrice ÷ TTM EPS-1.41x25.27x-1.14x62.36x
Forward P/EPrice ÷ next-FY EPS est.9.25x5.56x13.81x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple8.99x7.42x
Price / SalesMarket cap ÷ Revenue6.58x2.02x0.38x1.43x
Price / BookPrice ÷ Book value/share0.94x3.29x0.55x4.62x
Price / FCFMarket cap ÷ FCF9.62x11.12x15.98x
PRGO leads this category, winning 4 of 6 comparable metrics.

Profitability & Efficiency

Evenly matched — ANIP and AMRX each lead in 4 of 9 comparable metrics.

ANIP delivers a 14.5% return on equity — every $100 of shareholder capital generates $14 in annual profit, vs $-67 for LPCN. AMRX carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRGO's 1.35x. On the Piotroski fundamental quality scale (0–9), AMRX scores 8/9 vs LPCN's 0/9, reflecting strong financial health.

MetricLPCN logoLPCNLipocine Inc.ANIP logoANIPANI Pharmaceutica…PRGO logoPRGOPerrigo Company p…AMRX logoAMRXAmneal Pharmaceut…
ROE (TTM)Return on equity-66.7%+14.5%-50.7%+7.5%
ROA (TTM)Return on assets-59.4%+5.4%-19.8%+2.0%
ROICReturn on invested capital-64.7%+11.2%+3.7%-0.2%
ROCEReturn on capital employed-58.5%+9.9%+4.3%-0.2%
Piotroski ScoreFundamental quality 0–90648
Debt / EquityFinancial leverage0.60x1.35x0.13x
Net DebtTotal debt minus cash-$5M$40M$3.4B-$158M
Cash & Equiv.Liquid assets$5M$286M$532M$282M
Total DebtShort + long-term debt$0$325M$4.0B$124M
Interest CoverageEBIT ÷ Interest expense1.82x-7.20x2.09x
Evenly matched — ANIP and AMRX each lead in 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

AMRX leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in AMRX five years ago would be worth $26,385 today (with dividends reinvested), compared to $1,011 for LPCN. Over the past 12 months, AMRX leads with a +90.0% total return vs PRGO's -51.2%. The 3-year compound annual growth rate (CAGR) favors AMRX at 89.4% vs PRGO's -25.2% — a key indicator of consistent wealth creation.

MetricLPCN logoLPCNLipocine Inc.ANIP logoANIPANI Pharmaceutica…PRGO logoPRGOPerrigo Company p…AMRX logoAMRXAmneal Pharmaceut…
YTD ReturnYear-to-date-70.1%+7.0%-13.5%+8.4%
1-Year ReturnPast 12 months-27.6%+18.5%-51.2%+90.0%
3-Year ReturnCumulative with dividends-42.1%+97.1%-58.1%+579.2%
5-Year ReturnCumulative with dividends-89.9%+117.4%-60.1%+163.8%
10-Year ReturnCumulative with dividends-98.4%+84.7%-77.7%-54.9%
CAGR (3Y)Annualised 3-year return-16.7%+25.4%-25.2%+89.4%
AMRX leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ANIP and AMRX each lead in 1 of 2 comparable metrics.

ANIP is the less volatile stock with a 0.63 beta — it tends to amplify market swings less than PRGO's 1.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. AMRX currently trades 90.3% from its 52-week high vs LPCN's 19.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricLPCN logoLPCNLipocine Inc.ANIP logoANIPANI Pharmaceutica…PRGO logoPRGOPerrigo Company p…AMRX logoAMRXAmneal Pharmaceut…
Beta (5Y)Sensitivity to S&P 5000.86x0.63x1.18x1.17x
52-Week HighHighest price in past year$12.37$99.50$28.44$15.20
52-Week LowLowest price in past year$1.81$56.71$9.23$7.02
% of 52W HighCurrent price vs 52-week peak+19.3%+84.3%+41.2%+90.3%
RSI (14)Momentum oscillator 0–10034.164.460.962.7
Avg Volume (50D)Average daily shares traded463K328K3.4M1.7M
Evenly matched — ANIP and AMRX each lead in 1 of 2 comparable metrics.

Analyst Outlook

PRGO leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: ANIP as "Buy", PRGO as "Hold", AMRX as "Buy". Consensus price targets imply 70.6% upside for PRGO (target: $20) vs 23.9% for AMRX (target: $17). PRGO is the only dividend payer here at 9.81% yield — a key consideration for income-focused portfolios.

MetricLPCN logoLPCNLipocine Inc.ANIP logoANIPANI Pharmaceutica…PRGO logoPRGOPerrigo Company p…AMRX logoAMRXAmneal Pharmaceut…
Analyst RatingConsensus buy/hold/sellBuyHoldBuy
Price TargetConsensus 12-month target$124.00$20.00$17.00
# AnalystsCovering analysts103616
Dividend YieldAnnual dividend ÷ price+0.1%+9.8%
Dividend StreakConsecutive years of raises0100
Dividend / ShareAnnual DPS$0.05$1.15
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.7%0.0%0.0%
PRGO leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

PRGO leads in 2 of 6 categories (Valuation Metrics, Analyst Outlook). ANIP leads in 1 (Income & Cash Flow). 2 tied.

Best OverallPerrigo Company plc (PRGO)Leads 2 of 6 categories
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LPCN vs ANIP vs PRGO vs AMRX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is LPCN or ANIP or PRGO or AMRX a better buy right now?

For growth investors, ANI Pharmaceuticals, Inc.

(ANIP) is the stronger pick with 43. 8% revenue growth year-over-year, versus -82. 3% for Lipocine Inc. (LPCN). ANI Pharmaceuticals, Inc. (ANIP) offers the better valuation at 25. 3x trailing P/E (9. 2x forward), making it the more compelling value choice. Analysts rate ANI Pharmaceuticals, Inc. (ANIP) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — LPCN or ANIP or PRGO or AMRX?

On trailing P/E, ANI Pharmaceuticals, Inc.

(ANIP) is the cheapest at 25. 3x versus Amneal Pharmaceuticals, Inc. at 62. 4x. On forward P/E, Perrigo Company plc is actually cheaper at 5. 6x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — LPCN or ANIP or PRGO or AMRX?

Over the past 5 years, Amneal Pharmaceuticals, Inc.

(AMRX) delivered a total return of +163. 8%, compared to -89. 9% for Lipocine Inc. (LPCN). Over 10 years, the gap is even starker: ANIP returned +84. 7% versus LPCN's -98. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — LPCN or ANIP or PRGO or AMRX?

By beta (market sensitivity over 5 years), ANI Pharmaceuticals, Inc.

(ANIP) is the lower-risk stock at 0. 63β versus Perrigo Company plc's 1. 18β — meaning PRGO is approximately 88% more volatile than ANIP relative to the S&P 500. On balance sheet safety, Amneal Pharmaceuticals, Inc. (AMRX) carries a lower debt/equity ratio of 13% versus 135% for Perrigo Company plc — giving it more financial flexibility in a downturn.

05

Which is growing faster — LPCN or ANIP or PRGO or AMRX?

By revenue growth (latest reported year), ANI Pharmaceuticals, Inc.

(ANIP) is pulling ahead at 43. 8% versus -82. 3% for Lipocine Inc. (LPCN). On earnings-per-share growth, the picture is similar: ANI Pharmaceuticals, Inc. grew EPS 419. 2% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, LPCN leads at 58. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — LPCN or ANIP or PRGO or AMRX?

ANI Pharmaceuticals, Inc.

(ANIP) is the more profitable company, earning 8. 9% net margin versus -487. 1% for Lipocine Inc. — meaning it keeps 8. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ANIP leads at 12. 6% versus -524. 7% for LPCN. At the gross margin level — before operating expenses — ANIP leads at 69. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is LPCN or ANIP or PRGO or AMRX more undervalued right now?

On forward earnings alone, Perrigo Company plc (PRGO) trades at 5.

6x forward P/E versus 13. 8x for Amneal Pharmaceuticals, Inc. — 8. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PRGO: 70. 6% to $20. 00.

08

Which pays a better dividend — LPCN or ANIP or PRGO or AMRX?

In this comparison, PRGO (9.

8% yield) pays a dividend. LPCN, ANIP, AMRX do not pay a meaningful dividend and should not be held primarily for income.

09

Is LPCN or ANIP or PRGO or AMRX better for a retirement portfolio?

For long-horizon retirement investors, ANI Pharmaceuticals, Inc.

(ANIP) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 63)). Both have compounded well over 10 years (ANIP: +84. 7%, AMRX: -54. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between LPCN and ANIP and PRGO and AMRX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: LPCN is a small-cap quality compounder stock; ANIP is a small-cap high-growth stock; PRGO is a small-cap income-oriented stock; AMRX is a small-cap quality compounder stock. PRGO pays a dividend while LPCN, ANIP, AMRX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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AMRX

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  • Sector: Healthcare
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