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LSTA vs ADCT vs IMVT vs RCUS vs MGNX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
LSTA
Lisata Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$29M
5Y Perf.-88.9%
ADCT
ADC Therapeutics S.A.

Biotechnology

HealthcareNYSE • CH
Market Cap$445M
5Y Perf.-90.5%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.88B
5Y Perf.+12.8%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.55B
5Y Perf.-19.1%
MGNX
MacroGenics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$190M
5Y Perf.-84.4%

LSTA vs ADCT vs IMVT vs RCUS vs MGNX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
LSTA logoLSTA
ADCT logoADCT
IMVT logoIMVT
RCUS logoRCUS
MGNX logoMGNX
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$29M$445M$5.88B$2.55B$190M
Revenue (TTM)$170K$79M$0.00$236M$150M
Net Income (TTM)$-17M$-137M$-464M$-369M$-75M
Gross Margin91.2%90.7%90.7%
Operating Margin-107.1%-149.6%-168.6%-48.7%
Total Debt$0.00$439M$98K$99M$37M
Cash & Equiv.$16M$261M$714M$222M$57M

LSTA vs ADCT vs IMVT vs RCUS vs MGNXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

LSTA
ADCT
IMVT
RCUS
MGNX
StockMay 20May 26Return
Lisata Therapeutics… (LSTA)10011.1-88.9%
ADC Therapeutics S.… (ADCT)1009.5-90.5%
Immunovant, Inc. (IMVT)100112.8+12.8%
Arcus Biosciences, … (RCUS)10080.9-19.1%
MacroGenics, Inc. (MGNX)10015.6-84.4%

Price return only. Dividends and distributions are not included.

Quick Verdict: LSTA vs ADCT vs IMVT vs RCUS vs MGNX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: LSTA and ADCT are tied at the top with 1 category each (5-stock set) — the right choice depends on your priorities. ADC Therapeutics S.A. is the stronger pick specifically for growth and revenue expansion. IMVT, RCUS, and MGNX also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
LSTA
Lisata Therapeutics, Inc.
The Income Pick

LSTA has the current edge in this matchup, primarily because of its strength in income & stability and defensive.

  • Dividend streak 1 yrs, beta 1.09
  • Beta 1.09, current ratio 5.76x
  • Beta 1.09 vs ADCT's 1.84
Best for: income & stability and defensive
ADCT
ADC Therapeutics S.A.
The Growth Play

ADCT is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 14.9%, EPS growth 30.9%, 3Y rev CAGR -27.1%
  • 14.9% revenue growth vs LSTA's -83.0%
Best for: growth exposure
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT ranks third and is worth considering specifically for long-term compounding and sleep-well-at-night.

  • 190.9% 10Y total return vs RCUS's 49.2%
  • Lower volatility, beta 1.36, Low D/E 0.0%, current ratio 11.16x
  • 3.2% margin vs LSTA's -97.6%
Best for: long-term compounding and sleep-well-at-night
RCUS
Arcus Biosciences, Inc.
The Momentum Pick

RCUS is the clearest fit if your priority is momentum.

  • +197.3% vs LSTA's +32.9%
Best for: momentum
MGNX
MacroGenics, Inc.
The Niche Pick

MGNX is the clearest fit if your priority is efficiency.

  • -29.9% ROA vs LSTA's -70.8%, ROIC -18.8% vs -229.7%
Best for: efficiency
See the full category breakdown
CategoryWinnerWhy
GrowthADCT logoADCT14.9% revenue growth vs LSTA's -83.0%
Quality / MarginsIMVT logoIMVT3.2% margin vs LSTA's -97.6%
Stability / SafetyLSTA logoLSTABeta 1.09 vs ADCT's 1.84
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)RCUS logoRCUS+197.3% vs LSTA's +32.9%
Efficiency (ROA)MGNX logoMGNX-29.9% ROA vs LSTA's -70.8%, ROIC -18.8% vs -229.7%

LSTA vs ADCT vs IMVT vs RCUS vs MGNX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

LSTALisata Therapeutics, Inc.
FY 2025
Reportable Segment
100.0%$170,000
ADCTADC Therapeutics S.A.
FY 2025
Product
90.4%$74M
License Revenues
6.1%$5M
Royalty Revenue
3.4%$3M
IMVTImmunovant, Inc.

Segment breakdown not available.

RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M
MGNXMacroGenics, Inc.
FY 2025
Revenue From Collaborative Agreements
62.4%$87M
Contract Manufacturing
37.6%$53M

LSTA vs ADCT vs IMVT vs RCUS vs MGNX — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLIMVTLAGGINGRCUS

Income & Cash Flow (Last 12 Months)

MGNX leads this category, winning 4 of 6 comparable metrics.

RCUS and IMVT operate at a comparable scale, with $236M and $0 in trailing revenue. MGNX is the more profitable business, keeping -49.9% of every revenue dollar as net income compared to LSTA's -97.6%. On growth, MGNX holds the edge at +132.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricLSTA logoLSTALisata Therapeuti…ADCT logoADCTADC Therapeutics …IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…MGNX logoMGNXMacroGenics, Inc.
RevenueTrailing 12 months$170,000$79M$0$236M$150M
EBITDAEarnings before interest/tax-$18M-$117M-$487M-$391M-$73M
Net IncomeAfter-tax profit-$17M-$137M-$464M-$369M-$75M
Free Cash FlowCash after capex-$16M-$115M-$423M-$489M-$83M
Gross MarginGross profit ÷ Revenue+91.2%+90.7%+90.7%
Operating MarginEBIT ÷ Revenue-107.1%-149.6%-168.6%-48.7%
Net MarginNet income ÷ Revenue-97.6%-173.0%-156.4%-49.9%
FCF MarginFCF ÷ Revenue-94.1%-144.7%-2.1%-55.5%
Rev. Growth (YoY)Latest quarter vs prior year-90.0%-9.5%-39.3%+132.5%
EPS Growth (YoY)Latest quarter vs prior year+40.0%+41.7%+19.7%+10.5%+8.0%
MGNX leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

Evenly matched — LSTA and IMVT and MGNX each lead in 1 of 3 comparable metrics.
MetricLSTA logoLSTALisata Therapeuti…ADCT logoADCTADC Therapeutics …IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…MGNX logoMGNXMacroGenics, Inc.
Market CapShares × price$29M$445M$5.9B$2.6B$190M
Enterprise ValueMkt cap + debt − cash$13M$623M$5.2B$2.4B$170M
Trailing P/EPrice ÷ TTM EPS-1.65x-3.13x-10.60x-7.71x-2.54x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue168.74x5.47x10.34x1.27x
Price / BookPrice ÷ Book value/share1.87x6.20x4.32x3.41x
Price / FCFMarket cap ÷ FCF
Evenly matched — LSTA and IMVT and MGNX each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

IMVT leads this category, winning 3 of 9 comparable metrics.

IMVT delivers a -47.1% return on equity — every $100 of shareholder capital generates $-47 in annual profit, vs $-120 for MGNX. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to MGNX's 0.66x. On the Piotroski fundamental quality scale (0–9), ADCT scores 4/9 vs RCUS's 0/9, reflecting mixed financial health.

MetricLSTA logoLSTALisata Therapeuti…ADCT logoADCTADC Therapeutics …IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…MGNX logoMGNXMacroGenics, Inc.
ROE (TTM)Return on equity-85.5%-47.1%-69.0%-120.2%
ROA (TTM)Return on assets-70.8%-44.7%-44.1%-35.3%-29.9%
ROICReturn on invested capital-2.3%-64.1%-18.8%
ROCEReturn on capital employed-82.7%-43.8%-66.1%-42.1%-34.7%
Piotroski ScoreFundamental quality 0–914203
Debt / EquityFinancial leverage0.00x0.16x0.66x
Net DebtTotal debt minus cash-$16M$178M-$714M-$123M-$20M
Cash & Equiv.Liquid assets$16M$261M$714M$222M$57M
Total DebtShort + long-term debt$0$439M$98,000$99M$37M
Interest CoverageEBIT ÷ Interest expense-1.72x-13.38x
IMVT leads this category, winning 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — ADCT and IMVT each lead in 2 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $18,445 today (with dividends reinvested), compared to $985 for MGNX. Over the past 12 months, RCUS leads with a +197.3% total return vs LSTA's +32.9%. The 3-year compound annual growth rate (CAGR) favors ADCT at 18.2% vs MGNX's -25.4% — a key indicator of consistent wealth creation.

MetricLSTA logoLSTALisata Therapeuti…ADCT logoADCTADC Therapeutics …IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…MGNX logoMGNXMacroGenics, Inc.
YTD ReturnYear-to-date+60.7%-0.6%+11.7%+8.9%+86.3%
1-Year ReturnPast 12 months+32.9%+173.4%+102.4%+197.3%+94.8%
3-Year ReturnCumulative with dividends-3.7%+65.1%+49.8%+27.8%-58.6%
5-Year ReturnCumulative with dividends-85.8%-84.4%+84.4%-12.1%-90.2%
10-Year ReturnCumulative with dividends-96.9%-88.2%+190.9%+49.2%-84.0%
CAGR (3Y)Annualised 3-year return-1.2%+18.2%+14.4%+8.5%-25.4%
Evenly matched — ADCT and IMVT each lead in 2 of 6 comparable metrics.

Risk & Volatility

Evenly matched — LSTA and IMVT each lead in 1 of 2 comparable metrics.

LSTA is the less volatile stock with a 1.09 beta — it tends to amplify market swings less than ADCT's 1.84 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 96.2% from its 52-week high vs LSTA's 62.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricLSTA logoLSTALisata Therapeuti…ADCT logoADCTADC Therapeutics …IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…MGNX logoMGNXMacroGenics, Inc.
Beta (5Y)Sensitivity to S&P 5001.09x1.84x1.36x1.84x1.76x
52-Week HighHighest price in past year$5.07$4.97$30.09$28.72$3.88
52-Week LowLowest price in past year$1.81$1.23$13.36$7.72$1.19
% of 52W HighCurrent price vs 52-week peak+62.1%+70.4%+96.2%+88.3%+77.3%
RSI (14)Momentum oscillator 0–10034.544.150.652.942.6
Avg Volume (50D)Average daily shares traded76K967K1.4M1.2M1.1M
Evenly matched — LSTA and IMVT each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: ADCT as "Buy", IMVT as "Buy", RCUS as "Buy", MGNX as "Buy". Consensus price targets imply 114.3% upside for ADCT (target: $8) vs 18.3% for RCUS (target: $30).

MetricLSTA logoLSTALisata Therapeuti…ADCT logoADCTADC Therapeutics …IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…MGNX logoMGNXMacroGenics, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$7.50$45.50$30.00$6.00
# AnalystsCovering analysts12231822
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

MGNX leads in 1 of 6 categories (Income & Cash Flow). IMVT leads in 1 (Profitability & Efficiency). 3 tied.

Best OverallImmunovant, Inc. (IMVT)Leads 1 of 6 categories
Loading custom metrics...

LSTA vs ADCT vs IMVT vs RCUS vs MGNX: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is LSTA or ADCT or IMVT or RCUS or MGNX a better buy right now?

For growth investors, ADC Therapeutics S.

A. (ADCT) is the stronger pick with 14. 9% revenue growth year-over-year, versus -83. 0% for Lisata Therapeutics, Inc. (LSTA). Analysts rate ADC Therapeutics S. A. (ADCT) a "Buy" — based on 12 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — LSTA or ADCT or IMVT or RCUS or MGNX?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +84. 4%, compared to -90. 2% for MacroGenics, Inc. (MGNX). Over 10 years, the gap is even starker: IMVT returned +190. 9% versus LSTA's -96. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — LSTA or ADCT or IMVT or RCUS or MGNX?

By beta (market sensitivity over 5 years), Lisata Therapeutics, Inc.

(LSTA) is the lower-risk stock at 1. 09β versus ADC Therapeutics S. A. 's 1. 84β — meaning ADCT is approximately 69% more volatile than LSTA relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 66% for MacroGenics, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — LSTA or ADCT or IMVT or RCUS or MGNX?

By revenue growth (latest reported year), ADC Therapeutics S.

A. (ADCT) is pulling ahead at 14. 9% versus -83. 0% for Lisata Therapeutics, Inc. (LSTA). On earnings-per-share growth, the picture is similar: ADC Therapeutics S. A. grew EPS 30. 9% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — LSTA or ADCT or IMVT or RCUS or MGNX?

Immunovant, Inc.

(IMVT) is the more profitable company, earning 0. 0% net margin versus -97. 6% for Lisata Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -107. 1% for LSTA. At the gross margin level — before operating expenses — RCUS leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — LSTA or ADCT or IMVT or RCUS or MGNX?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is LSTA or ADCT or IMVT or RCUS or MGNX better for a retirement portfolio?

For long-horizon retirement investors, Lisata Therapeutics, Inc.

(LSTA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 09)). ADC Therapeutics S. A. (ADCT) carries a higher beta of 1. 84 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (LSTA: -96. 9%, ADCT: -88. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between LSTA and ADCT and IMVT and RCUS and MGNX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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LSTA

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  • Market Cap > $100B
  • Gross Margin > 54%
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  • Market Cap > $100B
  • Gross Margin > 54%
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  • Market Cap > $100B
  • Gross Margin > 54%
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  • Market Cap > $100B
  • Revenue Growth > 66%
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Revenue Growth>
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(LSTA: -90.0% · ADCT: -9.5%)

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