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MASI vs NVCR vs HOLX vs INVA vs ABT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MASI
Masimo Corporation

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$9.35B
5Y Perf.-25.7%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$1.92B
5Y Perf.-75.0%
HOLX
Hologic, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$16.97B
5Y Perf.+42.6%
INVA
Innoviva, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.93B
5Y Perf.+63.2%
ABT
Abbott Laboratories

Medical - Devices

HealthcareNYSE • US
Market Cap$151.30B
5Y Perf.-8.3%

MASI vs NVCR vs HOLX vs INVA vs ABT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MASI logoMASI
NVCR logoNVCR
HOLX logoHOLX
INVA logoINVA
ABT logoABT
IndustryMedical - Instruments & SuppliesMedical - Instruments & SuppliesMedical - Instruments & SuppliesBiotechnologyMedical - Devices
Market Cap$9.35B$1.92B$16.97B$1.93B$151.30B
Revenue (TTM)$1.56B$674M$4.13B$424M$43.84B
Net Income (TTM)$76M$-173M$544M$504M$13.98B
Gross Margin61.7%75.2%52.8%76.2%54.0%
Operating Margin19.9%-27.2%17.5%14.8%17.8%
Forward P/E32.5x17.2x11.9x15.9x
Total Debt$559M$290M$2.63B$269M$15.28B
Cash & Equiv.$152M$103M$1.96B$551M$7.62B

MASI vs NVCR vs HOLX vs INVA vs ABTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MASI
NVCR
HOLX
INVA
ABT
StockMay 20May 26Return
Masimo Corporation (MASI)10074.3-25.7%
NovoCure Limited (NVCR)10025.0-75.0%
Hologic, Inc. (HOLX)100142.6+42.6%
Innoviva, Inc. (INVA)100163.2+63.2%
Abbott Laboratories (ABT)10091.7-8.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: MASI vs NVCR vs HOLX vs INVA vs ABT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: INVA leads in 5 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. Hologic, Inc. is the stronger pick specifically for recent price momentum and sentiment. ABT also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
MASI
Masimo Corporation
The Long-Run Compounder

MASI is the clearest fit if your priority is long-term compounding.

  • 282.9% 10Y total return vs ABT's 173.7%
Best for: long-term compounding
NVCR
NovoCure Limited
The Healthcare Pick

Among these 5 stocks, NVCR doesn't own a clear edge in any measured category.

Best for: healthcare exposure
HOLX
Hologic, Inc.
The Momentum Pick

HOLX is the #2 pick in this set and the best alternative if momentum is your priority.

  • +37.1% vs ABT's -33.2%
Best for: momentum
INVA
Innoviva, Inc.
The Growth Play

INVA carries the broadest edge in this set and is the clearest fit for growth exposure and sleep-well-at-night.

  • Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
  • Lower volatility, beta 0.13, Low D/E 22.9%, current ratio 14.64x
  • Beta 0.13, current ratio 14.64x
  • 18.5% revenue growth vs MASI's -27.1%
Best for: growth exposure and sleep-well-at-night
ABT
Abbott Laboratories
The Income Pick

ABT ranks third and is worth considering specifically for income & stability and valuation efficiency.

  • Dividend streak 11 yrs, beta 0.25, yield 2.5%
  • PEG 0.53 vs INVA's 1.15
  • 2.5% yield; 11-year raise streak; the other 4 pay no meaningful dividend
Best for: income & stability and valuation efficiency
See the full category breakdown
CategoryWinnerWhy
GrowthINVA logoINVA18.5% revenue growth vs MASI's -27.1%
ValueINVA logoINVALower P/E (11.9x vs 17.2x)
Quality / MarginsINVA logoINVA118.9% margin vs NVCR's -25.7%
Stability / SafetyINVA logoINVABeta 0.13 vs NVCR's 2.20, lower leverage
DividendsABT logoABT2.5% yield; 11-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)HOLX logoHOLX+37.1% vs ABT's -33.2%
Efficiency (ROA)INVA logoINVA32.4% ROA vs NVCR's -16.5%, ROIC 14.2% vs -16.4%

MASI vs NVCR vs HOLX vs INVA vs ABT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MASIMasimo Corporation
FY 2025
Health Care Segment
100.0%$1.5B
NVCRNovoCure Limited

Segment breakdown not available.

HOLXHologic, Inc.
FY 2025
Diagnostics
44.6%$1.8B
Breast Health
36.2%$1.5B
Gyn Surgical
16.6%$680M
Skeletal Health
2.7%$109M
INVAInnoviva, Inc.
FY 2025
Royalty
57.5%$236M
Product
41.8%$172M
License And Other Revenue
0.7%$3M
ABTAbbott Laboratories
FY 2024
Medical Devices
45.3%$19.0B
Diagnostic Products
22.3%$9.3B
Nutritional Products
20.1%$8.4B
Established Pharmaceutical Products
12.4%$5.2B

MASI vs NVCR vs HOLX vs INVA vs ABT — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLINVALAGGINGHOLX

Income & Cash Flow (Last 12 Months)

INVA leads this category, winning 4 of 6 comparable metrics.

ABT is the larger business by revenue, generating $43.8B annually — 103.4x INVA's $424M. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to NVCR's -25.7%. On growth, NVCR holds the edge at +12.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricMASI logoMASIMasimo CorporationNVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.INVA logoINVAInnoviva, Inc.ABT logoABTAbbott Laboratori…
RevenueTrailing 12 months$1.6B$674M$4.1B$424M$43.8B
EBITDAEarnings before interest/tax$340M-$165M$974M$86M$10.9B
Net IncomeAfter-tax profit$76M-$173M$544M$504M$14.0B
Free Cash FlowCash after capex$211M-$48M$1000M$181M$6.9B
Gross MarginGross profit ÷ Revenue+61.7%+75.2%+52.8%+76.2%+54.0%
Operating MarginEBIT ÷ Revenue+19.9%-27.2%+17.5%+14.8%+17.8%
Net MarginNet income ÷ Revenue+4.9%-25.7%+13.2%+118.9%+31.9%
FCF MarginFCF ÷ Revenue+13.6%-7.1%+24.2%+42.8%+15.8%
Rev. Growth (YoY)Latest quarter vs prior year+8.5%+12.3%+2.5%+10.6%+6.9%
EPS Growth (YoY)Latest quarter vs prior year+134.4%-100.0%-9.2%+4.0%0.0%
INVA leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

INVA leads this category, winning 4 of 7 comparable metrics.

At 6.9x trailing earnings, INVA trades at a 77% valuation discount to HOLX's 30.5x P/E. Adjusting for growth (PEG ratio), ABT offers better value at 0.38x vs INVA's 0.67x — a lower PEG means you pay less per unit of expected earnings growth.

MetricMASI logoMASIMasimo CorporationNVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.INVA logoINVAInnoviva, Inc.ABT logoABTAbbott Laboratori…
Market CapShares × price$9.3B$1.9B$17.0B$1.9B$151.3B
Enterprise ValueMkt cap + debt − cash$9.8B$2.1B$17.6B$1.7B$159.0B
Trailing P/EPrice ÷ TTM EPS-63.75x-13.80x30.53x6.91x11.39x
Forward P/EPrice ÷ next-FY EPS est.32.46x17.21x11.91x15.87x
PEG RatioP/E ÷ EPS growth rate0.67x0.38x
EV / EBITDAEnterprise value multiple27.74x17.39x8.10x15.83x
Price / SalesMarket cap ÷ Revenue6.12x2.92x4.14x4.55x3.61x
Price / BookPrice ÷ Book value/share13.41x5.51x3.43x1.65x3.18x
Price / FCFMarket cap ÷ FCF47.26x18.44x9.88x23.82x
INVA leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

INVA leads this category, winning 6 of 9 comparable metrics.

INVA delivers a 46.5% return on equity — every $100 of shareholder capital generates $46 in annual profit, vs $-51 for NVCR. INVA carries lower financial leverage with a 0.23x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), HOLX scores 7/9 vs INVA's 5/9, reflecting strong financial health.

MetricMASI logoMASIMasimo CorporationNVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.INVA logoINVAInnoviva, Inc.ABT logoABTAbbott Laboratori…
ROE (TTM)Return on equity+9.1%-50.8%+11.0%+46.5%+27.3%
ROA (TTM)Return on assets+4.0%-16.5%+6.1%+32.4%+16.6%
ROICReturn on invested capital+16.5%-16.4%+9.4%+14.2%+9.9%
ROCEReturn on capital employed+18.8%-28.9%+8.8%+12.4%+10.8%
Piotroski ScoreFundamental quality 0–965757
Debt / EquityFinancial leverage0.78x0.85x0.52x0.23x0.32x
Net DebtTotal debt minus cash$407M$187M$667M-$282M$7.7B
Cash & Equiv.Liquid assets$152M$103M$2.0B$551M$7.6B
Total DebtShort + long-term debt$559M$290M$2.6B$269M$15.3B
Interest CoverageEBIT ÷ Interest expense12.50x-96.80x8.00x63.45x19.22x
INVA leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

INVA leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in INVA five years ago would be worth $19,437 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, HOLX leads with a +37.1% total return vs ABT's -33.2%. The 3-year compound annual growth rate (CAGR) favors INVA at 25.0% vs NVCR's -37.6% — a key indicator of consistent wealth creation.

MetricMASI logoMASIMasimo CorporationNVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.INVA logoINVAInnoviva, Inc.ABT logoABTAbbott Laboratori…
YTD ReturnYear-to-date+40.1%+28.3%+1.9%+14.7%-28.9%
1-Year ReturnPast 12 months+18.9%+1.1%+37.1%+21.7%-33.2%
3-Year ReturnCumulative with dividends-4.9%-75.7%-8.5%+95.2%-15.4%
5-Year ReturnCumulative with dividends-20.4%-91.3%+15.8%+94.4%-17.9%
10-Year ReturnCumulative with dividends+282.9%+30.3%+124.3%+94.9%+173.7%
CAGR (3Y)Annualised 3-year return-1.7%-37.6%-2.9%+25.0%-5.4%
INVA leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — HOLX and INVA each lead in 1 of 2 comparable metrics.

INVA is the less volatile stock with a 0.13 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs ABT's 62.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMASI logoMASIMasimo CorporationNVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.INVA logoINVAInnoviva, Inc.ABT logoABTAbbott Laboratori…
Beta (5Y)Sensitivity to S&P 5000.63x2.20x0.41x0.13x0.25x
52-Week HighHighest price in past year$179.10$20.06$76.04$25.15$139.06
52-Week LowLowest price in past year$125.94$9.82$52.81$16.52$86.15
% of 52W HighCurrent price vs 52-week peak+99.7%+83.9%+100.0%+90.7%+62.6%
RSI (14)Momentum oscillator 0–10063.869.869.139.922.9
Avg Volume (50D)Average daily shares traded1.2M1.5M10.0M621K10.5M
Evenly matched — HOLX and INVA each lead in 1 of 2 comparable metrics.

Analyst Outlook

ABT leads this category, winning 1 of 1 comparable metric.

Analyst consensus: MASI as "Buy", NVCR as "Buy", HOLX as "Hold", INVA as "Buy", ABT as "Buy". Consensus price targets imply 99.0% upside for NVCR (target: $34) vs 3.9% for HOLX (target: $79). ABT is the only dividend payer here at 2.52% yield — a key consideration for income-focused portfolios.

MetricMASI logoMASIMasimo CorporationNVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.INVA logoINVAInnoviva, Inc.ABT logoABTAbbott Laboratori…
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuyBuy
Price TargetConsensus 12-month target$187.50$33.50$79.00$37.67$128.71
# AnalystsCovering analysts2315421041
Dividend YieldAnnual dividend ÷ price+2.5%
Dividend StreakConsecutive years of raises0011
Dividend / ShareAnnual DPS$2.19
Buyback YieldShare repurchases ÷ mkt cap+3.9%0.0%+4.4%+0.2%+0.9%
ABT leads this category, winning 1 of 1 comparable metric.
Key Takeaway

INVA leads in 4 of 6 categories (Income & Cash Flow, Valuation Metrics). ABT leads in 1 (Analyst Outlook). 1 tied.

Best OverallInnoviva, Inc. (INVA)Leads 4 of 6 categories
Loading custom metrics...

MASI vs NVCR vs HOLX vs INVA vs ABT: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is MASI or NVCR or HOLX or INVA or ABT a better buy right now?

For growth investors, Innoviva, Inc.

(INVA) is the stronger pick with 18. 5% revenue growth year-over-year, versus -27. 1% for Masimo Corporation (MASI). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (11. 9x forward), making it the more compelling value choice. Analysts rate Masimo Corporation (MASI) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — MASI or NVCR or HOLX or INVA or ABT?

On trailing P/E, Innoviva, Inc.

(INVA) is the cheapest at 6. 9x versus Hologic, Inc. at 30. 5x. On forward P/E, Innoviva, Inc. is actually cheaper at 11. 9x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Abbott Laboratories wins at 0. 53x versus Innoviva, Inc. 's 1. 15x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — MASI or NVCR or HOLX or INVA or ABT?

Over the past 5 years, Innoviva, Inc.

(INVA) delivered a total return of +94. 4%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: MASI returned +282. 9% versus NVCR's +30. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — MASI or NVCR or HOLX or INVA or ABT?

By beta (market sensitivity over 5 years), Innoviva, Inc.

(INVA) is the lower-risk stock at 0. 13β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 1648% more volatile than INVA relative to the S&P 500. On balance sheet safety, Innoviva, Inc. (INVA) carries a lower debt/equity ratio of 23% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.

05

Which is growing faster — MASI or NVCR or HOLX or INVA or ABT?

By revenue growth (latest reported year), Innoviva, Inc.

(INVA) is pulling ahead at 18. 5% versus -27. 1% for Masimo Corporation (MASI). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -25. 0% for Hologic, Inc.. Over a 3-year CAGR, INVA leads at 8. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — MASI or NVCR or HOLX or INVA or ABT?

Innoviva, Inc.

(INVA) is the more profitable company, earning 63. 8% net margin versus -20. 8% for NovoCure Limited — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -23. 5% for NVCR. At the gross margin level — before operating expenses — NVCR leads at 74. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is MASI or NVCR or HOLX or INVA or ABT more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Abbott Laboratories (ABT) is the more undervalued stock at a PEG of 0. 53x versus Innoviva, Inc. 's 1. 15x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Innoviva, Inc. (INVA) trades at 11. 9x forward P/E versus 32. 5x for Masimo Corporation — 20. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NVCR: 99. 0% to $33. 50.

08

Which pays a better dividend — MASI or NVCR or HOLX or INVA or ABT?

In this comparison, ABT (2.

5% yield) pays a dividend. MASI, NVCR, HOLX, INVA do not pay a meaningful dividend and should not be held primarily for income.

09

Is MASI or NVCR or HOLX or INVA or ABT better for a retirement portfolio?

For long-horizon retirement investors, Abbott Laboratories (ABT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

25), 2. 5% yield, +173. 7% 10Y return). NovoCure Limited (NVCR) carries a higher beta of 2. 20 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ABT: +173. 7%, NVCR: +30. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between MASI and NVCR and HOLX and INVA and ABT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: MASI is a small-cap quality compounder stock; NVCR is a small-cap quality compounder stock; HOLX is a mid-cap quality compounder stock; INVA is a small-cap high-growth stock; ABT is a mid-cap deep-value stock. ABT pays a dividend while MASI, NVCR, HOLX, INVA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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MASI

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  • Market Cap > $100B
  • Revenue Growth > 5%
  • Gross Margin > 37%
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  • Market Cap > $100B
  • Revenue Growth > 6%
  • Gross Margin > 45%
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  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 7%
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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
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ABT

Dividend Mega-Cap Quality

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  • Market Cap > $100B
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Beat Both

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Revenue Growth>
%
(MASI: 8.5% · NVCR: 12.3%)

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