Medical - Instruments & Supplies
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5 / 10Stock Comparison
MASI vs NVCR vs HOLX vs INVA vs ABT
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Instruments & Supplies
Medical - Instruments & Supplies
Biotechnology
Medical - Devices
MASI vs NVCR vs HOLX vs INVA vs ABT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Medical - Instruments & Supplies | Medical - Instruments & Supplies | Medical - Instruments & Supplies | Biotechnology | Medical - Devices |
| Market Cap | $9.35B | $1.92B | $16.97B | $1.93B | $151.30B |
| Revenue (TTM) | $1.56B | $674M | $4.13B | $424M | $43.84B |
| Net Income (TTM) | $76M | $-173M | $544M | $504M | $13.98B |
| Gross Margin | 61.7% | 75.2% | 52.8% | 76.2% | 54.0% |
| Operating Margin | 19.9% | -27.2% | 17.5% | 14.8% | 17.8% |
| Forward P/E | 32.5x | — | 17.2x | 11.9x | 15.9x |
| Total Debt | $559M | $290M | $2.63B | $269M | $15.28B |
| Cash & Equiv. | $152M | $103M | $1.96B | $551M | $7.62B |
MASI vs NVCR vs HOLX vs INVA vs ABT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Masimo Corporation (MASI) | 100 | 74.3 | -25.7% |
| NovoCure Limited (NVCR) | 100 | 25.0 | -75.0% |
| Hologic, Inc. (HOLX) | 100 | 142.6 | +42.6% |
| Innoviva, Inc. (INVA) | 100 | 163.2 | +63.2% |
| Abbott Laboratories (ABT) | 100 | 91.7 | -8.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: MASI vs NVCR vs HOLX vs INVA vs ABT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
MASI is the clearest fit if your priority is long-term compounding.
- 282.9% 10Y total return vs ABT's 173.7%
Among these 5 stocks, NVCR doesn't own a clear edge in any measured category.
HOLX is the #2 pick in this set and the best alternative if momentum is your priority.
- +37.1% vs ABT's -33.2%
INVA carries the broadest edge in this set and is the clearest fit for growth exposure and sleep-well-at-night.
- Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
- Lower volatility, beta 0.13, Low D/E 22.9%, current ratio 14.64x
- Beta 0.13, current ratio 14.64x
- 18.5% revenue growth vs MASI's -27.1%
ABT ranks third and is worth considering specifically for income & stability and valuation efficiency.
- Dividend streak 11 yrs, beta 0.25, yield 2.5%
- PEG 0.53 vs INVA's 1.15
- 2.5% yield; 11-year raise streak; the other 4 pay no meaningful dividend
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 18.5% revenue growth vs MASI's -27.1% | |
| Value | Lower P/E (11.9x vs 17.2x) | |
| Quality / Margins | 118.9% margin vs NVCR's -25.7% | |
| Stability / Safety | Beta 0.13 vs NVCR's 2.20, lower leverage | |
| Dividends | 2.5% yield; 11-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +37.1% vs ABT's -33.2% | |
| Efficiency (ROA) | 32.4% ROA vs NVCR's -16.5%, ROIC 14.2% vs -16.4% |
MASI vs NVCR vs HOLX vs INVA vs ABT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
MASI vs NVCR vs HOLX vs INVA vs ABT — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
INVA leads in 4 of 6 categories
ABT leads 1 • MASI leads 0 • NVCR leads 0 • HOLX leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
INVA leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ABT is the larger business by revenue, generating $43.8B annually — 103.4x INVA's $424M. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to NVCR's -25.7%. On growth, NVCR holds the edge at +12.3% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $1.6B | $674M | $4.1B | $424M | $43.8B |
| EBITDAEarnings before interest/tax | $340M | -$165M | $974M | $86M | $10.9B |
| Net IncomeAfter-tax profit | $76M | -$173M | $544M | $504M | $14.0B |
| Free Cash FlowCash after capex | $211M | -$48M | $1000M | $181M | $6.9B |
| Gross MarginGross profit ÷ Revenue | +61.7% | +75.2% | +52.8% | +76.2% | +54.0% |
| Operating MarginEBIT ÷ Revenue | +19.9% | -27.2% | +17.5% | +14.8% | +17.8% |
| Net MarginNet income ÷ Revenue | +4.9% | -25.7% | +13.2% | +118.9% | +31.9% |
| FCF MarginFCF ÷ Revenue | +13.6% | -7.1% | +24.2% | +42.8% | +15.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | +8.5% | +12.3% | +2.5% | +10.6% | +6.9% |
| EPS Growth (YoY)Latest quarter vs prior year | +134.4% | -100.0% | -9.2% | +4.0% | 0.0% |
Valuation Metrics
INVA leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 6.9x trailing earnings, INVA trades at a 77% valuation discount to HOLX's 30.5x P/E. Adjusting for growth (PEG ratio), ABT offers better value at 0.38x vs INVA's 0.67x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $9.3B | $1.9B | $17.0B | $1.9B | $151.3B |
| Enterprise ValueMkt cap + debt − cash | $9.8B | $2.1B | $17.6B | $1.7B | $159.0B |
| Trailing P/EPrice ÷ TTM EPS | -63.75x | -13.80x | 30.53x | 6.91x | 11.39x |
| Forward P/EPrice ÷ next-FY EPS est. | 32.46x | — | 17.21x | 11.91x | 15.87x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | 0.67x | 0.38x |
| EV / EBITDAEnterprise value multiple | 27.74x | — | 17.39x | 8.10x | 15.83x |
| Price / SalesMarket cap ÷ Revenue | 6.12x | 2.92x | 4.14x | 4.55x | 3.61x |
| Price / BookPrice ÷ Book value/share | 13.41x | 5.51x | 3.43x | 1.65x | 3.18x |
| Price / FCFMarket cap ÷ FCF | 47.26x | — | 18.44x | 9.88x | 23.82x |
Profitability & Efficiency
INVA leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
INVA delivers a 46.5% return on equity — every $100 of shareholder capital generates $46 in annual profit, vs $-51 for NVCR. INVA carries lower financial leverage with a 0.23x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), HOLX scores 7/9 vs INVA's 5/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +9.1% | -50.8% | +11.0% | +46.5% | +27.3% |
| ROA (TTM)Return on assets | +4.0% | -16.5% | +6.1% | +32.4% | +16.6% |
| ROICReturn on invested capital | +16.5% | -16.4% | +9.4% | +14.2% | +9.9% |
| ROCEReturn on capital employed | +18.8% | -28.9% | +8.8% | +12.4% | +10.8% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 5 | 7 | 5 | 7 |
| Debt / EquityFinancial leverage | 0.78x | 0.85x | 0.52x | 0.23x | 0.32x |
| Net DebtTotal debt minus cash | $407M | $187M | $667M | -$282M | $7.7B |
| Cash & Equiv.Liquid assets | $152M | $103M | $2.0B | $551M | $7.6B |
| Total DebtShort + long-term debt | $559M | $290M | $2.6B | $269M | $15.3B |
| Interest CoverageEBIT ÷ Interest expense | 12.50x | -96.80x | 8.00x | 63.45x | 19.22x |
Total Returns (Dividends Reinvested)
INVA leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in INVA five years ago would be worth $19,437 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, HOLX leads with a +37.1% total return vs ABT's -33.2%. The 3-year compound annual growth rate (CAGR) favors INVA at 25.0% vs NVCR's -37.6% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +40.1% | +28.3% | +1.9% | +14.7% | -28.9% |
| 1-Year ReturnPast 12 months | +18.9% | +1.1% | +37.1% | +21.7% | -33.2% |
| 3-Year ReturnCumulative with dividends | -4.9% | -75.7% | -8.5% | +95.2% | -15.4% |
| 5-Year ReturnCumulative with dividends | -20.4% | -91.3% | +15.8% | +94.4% | -17.9% |
| 10-Year ReturnCumulative with dividends | +282.9% | +30.3% | +124.3% | +94.9% | +173.7% |
| CAGR (3Y)Annualised 3-year return | -1.7% | -37.6% | -2.9% | +25.0% | -5.4% |
Risk & Volatility
Evenly matched — HOLX and INVA each lead in 1 of 2 comparable metrics.
Risk & Volatility
INVA is the less volatile stock with a 0.13 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs ABT's 62.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.63x | 2.20x | 0.41x | 0.13x | 0.25x |
| 52-Week HighHighest price in past year | $179.10 | $20.06 | $76.04 | $25.15 | $139.06 |
| 52-Week LowLowest price in past year | $125.94 | $9.82 | $52.81 | $16.52 | $86.15 |
| % of 52W HighCurrent price vs 52-week peak | +99.7% | +83.9% | +100.0% | +90.7% | +62.6% |
| RSI (14)Momentum oscillator 0–100 | 63.8 | 69.8 | 69.1 | 39.9 | 22.9 |
| Avg Volume (50D)Average daily shares traded | 1.2M | 1.5M | 10.0M | 621K | 10.5M |
Analyst Outlook
ABT leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: MASI as "Buy", NVCR as "Buy", HOLX as "Hold", INVA as "Buy", ABT as "Buy". Consensus price targets imply 99.0% upside for NVCR (target: $34) vs 3.9% for HOLX (target: $79). ABT is the only dividend payer here at 2.52% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | $187.50 | $33.50 | $79.00 | $37.67 | $128.71 |
| # AnalystsCovering analysts | 23 | 15 | 42 | 10 | 41 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | +2.5% |
| Dividend StreakConsecutive years of raises | 0 | — | — | 0 | 11 |
| Dividend / ShareAnnual DPS | — | — | — | — | $2.19 |
| Buyback YieldShare repurchases ÷ mkt cap | +3.9% | 0.0% | +4.4% | +0.2% | +0.9% |
INVA leads in 4 of 6 categories (Income & Cash Flow, Valuation Metrics). ABT leads in 1 (Analyst Outlook). 1 tied.
MASI vs NVCR vs HOLX vs INVA vs ABT: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is MASI or NVCR or HOLX or INVA or ABT a better buy right now?
For growth investors, Innoviva, Inc.
(INVA) is the stronger pick with 18. 5% revenue growth year-over-year, versus -27. 1% for Masimo Corporation (MASI). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (11. 9x forward), making it the more compelling value choice. Analysts rate Masimo Corporation (MASI) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — MASI or NVCR or HOLX or INVA or ABT?
On trailing P/E, Innoviva, Inc.
(INVA) is the cheapest at 6. 9x versus Hologic, Inc. at 30. 5x. On forward P/E, Innoviva, Inc. is actually cheaper at 11. 9x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Abbott Laboratories wins at 0. 53x versus Innoviva, Inc. 's 1. 15x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — MASI or NVCR or HOLX or INVA or ABT?
Over the past 5 years, Innoviva, Inc.
(INVA) delivered a total return of +94. 4%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: MASI returned +282. 9% versus NVCR's +30. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — MASI or NVCR or HOLX or INVA or ABT?
By beta (market sensitivity over 5 years), Innoviva, Inc.
(INVA) is the lower-risk stock at 0. 13β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 1648% more volatile than INVA relative to the S&P 500. On balance sheet safety, Innoviva, Inc. (INVA) carries a lower debt/equity ratio of 23% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.
05Which is growing faster — MASI or NVCR or HOLX or INVA or ABT?
By revenue growth (latest reported year), Innoviva, Inc.
(INVA) is pulling ahead at 18. 5% versus -27. 1% for Masimo Corporation (MASI). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -25. 0% for Hologic, Inc.. Over a 3-year CAGR, INVA leads at 8. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — MASI or NVCR or HOLX or INVA or ABT?
Innoviva, Inc.
(INVA) is the more profitable company, earning 63. 8% net margin versus -20. 8% for NovoCure Limited — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -23. 5% for NVCR. At the gross margin level — before operating expenses — NVCR leads at 74. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is MASI or NVCR or HOLX or INVA or ABT more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Abbott Laboratories (ABT) is the more undervalued stock at a PEG of 0. 53x versus Innoviva, Inc. 's 1. 15x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Innoviva, Inc. (INVA) trades at 11. 9x forward P/E versus 32. 5x for Masimo Corporation — 20. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NVCR: 99. 0% to $33. 50.
08Which pays a better dividend — MASI or NVCR or HOLX or INVA or ABT?
In this comparison, ABT (2.
5% yield) pays a dividend. MASI, NVCR, HOLX, INVA do not pay a meaningful dividend and should not be held primarily for income.
09Is MASI or NVCR or HOLX or INVA or ABT better for a retirement portfolio?
For long-horizon retirement investors, Abbott Laboratories (ABT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
25), 2. 5% yield, +173. 7% 10Y return). NovoCure Limited (NVCR) carries a higher beta of 2. 20 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ABT: +173. 7%, NVCR: +30. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between MASI and NVCR and HOLX and INVA and ABT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: MASI is a small-cap quality compounder stock; NVCR is a small-cap quality compounder stock; HOLX is a mid-cap quality compounder stock; INVA is a small-cap high-growth stock; ABT is a mid-cap deep-value stock. ABT pays a dividend while MASI, NVCR, HOLX, INVA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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