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Stock Comparison

MLSS vs SYK

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MLSS
Milestone Scientific Inc.

Medical - Instruments & Supplies

HealthcareAMEX • US
Market Cap$36M
5Y Perf.-75.2%
SYK
Stryker Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$109.33B
5Y Perf.+45.8%

MLSS vs SYK — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MLSS logoMLSS
SYK logoSYK
IndustryMedical - Instruments & SuppliesMedical - Devices
Market Cap$36M$109.33B
Revenue (TTM)$9M$25.12B
Net Income (TTM)$-7M$3.25B
Gross Margin72.8%63.5%
Operating Margin-77.0%22.4%
Forward P/E19.1x
Total Debt$349K$14.86B
Cash & Equiv.$3M$4.01B

MLSS vs SYKLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MLSS
SYK
StockMay 20May 26Return
Milestone Scientifi… (MLSS)10024.8-75.2%
Stryker Corporation (SYK)100145.8+45.8%

Price return only. Dividends and distributions are not included.

Quick Verdict: MLSS vs SYK

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: SYK leads in 6 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. As sector peers, any of these can serve as alternatives in the same allocation.
MLSS
Milestone Scientific Inc.
The Defensive Pick

MLSS is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 0.85, Low D/E 6.0%, current ratio 2.48x
Best for: sleep-well-at-night
SYK
Stryker Corporation
The Income Pick

SYK carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 34 yrs, beta 0.52, yield 1.2%
  • Rev growth 11.2%, EPS growth 8.2%, 3Y rev CAGR 10.8%
  • 179.2% 10Y total return vs MLSS's -80.4%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthSYK logoSYK11.2% revenue growth vs MLSS's -12.2%
Quality / MarginsSYK logoSYK12.9% margin vs MLSS's -76.8%
Stability / SafetySYK logoSYKBeta 0.52 vs MLSS's 0.85
DividendsSYK logoSYK1.2% yield; 34-year raise streak; the other pay no meaningful dividend
Momentum (1Y)SYK logoSYK-24.5% vs MLSS's -52.9%
Efficiency (ROA)SYK logoSYK6.9% ROA vs MLSS's -86.6%, ROIC 11.4% vs -121.3%

MLSS vs SYK — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MLSSMilestone Scientific Inc.
FY 2015
Handpieces
100.0%$6M
SYKStryker Corporation
FY 2025
MedSurg
62.3%$15.6B
Orthopaedics
37.7%$9.5B

MLSS vs SYK — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLSYKLAGGINGMLSS

Income & Cash Flow (Last 12 Months)

SYK leads this category, winning 3 of 5 comparable metrics.

SYK is the larger business by revenue, generating $25.1B annually — 2765.1x MLSS's $9M. SYK is the more profitable business, keeping 12.9% of every revenue dollar as net income compared to MLSS's -76.8%. On growth, MLSS holds the edge at +25.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricMLSS logoMLSSMilestone Scienti…SYK logoSYKStryker Corporati…
RevenueTrailing 12 months$9M$25.1B
EBITDAEarnings before interest/tax-$7M$6.3B
Net IncomeAfter-tax profit-$7M$3.2B
Free Cash FlowCash after capex-$5M$4.3B
Gross MarginGross profit ÷ Revenue+72.8%+63.5%
Operating MarginEBIT ÷ Revenue-77.0%+22.4%
Net MarginNet income ÷ Revenue-76.8%+12.9%
FCF MarginFCF ÷ Revenue-57.9%+17.1%
Rev. Growth (YoY)Latest quarter vs prior year+25.3%+11.4%
EPS Growth (YoY)Latest quarter vs prior year+56.0%
SYK leads this category, winning 3 of 5 comparable metrics.

Valuation Metrics

MLSS leads this category, winning 2 of 3 comparable metrics.
MetricMLSS logoMLSSMilestone Scienti…SYK logoSYKStryker Corporati…
Market CapShares × price$36M$109.3B
Enterprise ValueMkt cap + debt − cash$33M$120.2B
Trailing P/EPrice ÷ TTM EPS-7.73x33.98x
Forward P/EPrice ÷ next-FY EPS est.19.06x
PEG RatioP/E ÷ EPS growth rate2.29x
EV / EBITDAEnterprise value multiple19.76x
Price / SalesMarket cap ÷ Revenue4.16x4.35x
Price / BookPrice ÷ Book value/share6.25x4.87x
Price / FCFMarket cap ÷ FCF25.53x
MLSS leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

SYK leads this category, winning 5 of 8 comparable metrics.

SYK delivers a 15.0% return on equity — every $100 of shareholder capital generates $15 in annual profit, vs $-2 for MLSS. MLSS carries lower financial leverage with a 0.06x debt-to-equity ratio, signaling a more conservative balance sheet compared to SYK's 0.66x. On the Piotroski fundamental quality scale (0–9), SYK scores 6/9 vs MLSS's 4/9, reflecting solid financial health.

MetricMLSS logoMLSSMilestone Scienti…SYK logoSYKStryker Corporati…
ROE (TTM)Return on equity-2.1%+15.0%
ROA (TTM)Return on assets-86.6%+6.9%
ROICReturn on invested capital-121.3%+11.4%
ROCEReturn on capital employed-94.2%+13.0%
Piotroski ScoreFundamental quality 0–946
Debt / EquityFinancial leverage0.06x0.66x
Net DebtTotal debt minus cash-$3M$10.8B
Cash & Equiv.Liquid assets$3M$4.0B
Total DebtShort + long-term debt$349,054$14.9B
Interest CoverageEBIT ÷ Interest expense6.72x
SYK leads this category, winning 5 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

SYK leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in SYK five years ago would be worth $11,752 today (with dividends reinvested), compared to $1,945 for MLSS. Over the past 12 months, SYK leads with a -24.5% total return vs MLSS's -52.9%. The 3-year compound annual growth rate (CAGR) favors SYK at 0.8% vs MLSS's -15.2% — a key indicator of consistent wealth creation.

MetricMLSS logoMLSSMilestone Scienti…SYK logoSYKStryker Corporati…
YTD ReturnYear-to-date+57.6%-17.8%
1-Year ReturnPast 12 months-52.9%-24.5%
3-Year ReturnCumulative with dividends-39.1%+2.4%
5-Year ReturnCumulative with dividends-80.6%+17.5%
10-Year ReturnCumulative with dividends-80.4%+179.2%
CAGR (3Y)Annualised 3-year return-15.2%+0.8%
SYK leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

SYK leads this category, winning 2 of 2 comparable metrics.

SYK is the less volatile stock with a 0.52 beta — it tends to amplify market swings less than MLSS's 0.85 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. SYK currently trades 70.5% from its 52-week high vs MLSS's 43.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMLSS logoMLSSMilestone Scienti…SYK logoSYKStryker Corporati…
Beta (5Y)Sensitivity to S&P 5000.85x0.52x
52-Week HighHighest price in past year$1.05$404.87
52-Week LowLowest price in past year$0.22$284.97
% of 52W HighCurrent price vs 52-week peak+43.5%+70.5%
RSI (14)Momentum oscillator 0–10079.726.6
Avg Volume (50D)Average daily shares traded2.3M2.1M
SYK leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

SYK is the only dividend payer here at 1.18% yield — a key consideration for income-focused portfolios.

MetricMLSS logoMLSSMilestone Scienti…SYK logoSYKStryker Corporati…
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target$389.62
# AnalystsCovering analysts50
Dividend YieldAnnual dividend ÷ price+1.2%
Dividend StreakConsecutive years of raises34
Dividend / ShareAnnual DPS$3.36
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

SYK leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). MLSS leads in 1 (Valuation Metrics).

Best OverallStryker Corporation (SYK)Leads 4 of 6 categories
Loading custom metrics...

MLSS vs SYK: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is MLSS or SYK a better buy right now?

For growth investors, Stryker Corporation (SYK) is the stronger pick with 11.

2% revenue growth year-over-year, versus -12. 2% for Milestone Scientific Inc. (MLSS). Stryker Corporation (SYK) offers the better valuation at 34. 0x trailing P/E (19. 1x forward), making it the more compelling value choice. Analysts rate Stryker Corporation (SYK) a "Buy" — based on 50 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — MLSS or SYK?

Over the past 5 years, Stryker Corporation (SYK) delivered a total return of +17.

5%, compared to -80. 6% for Milestone Scientific Inc. (MLSS). Over 10 years, the gap is even starker: SYK returned +179. 2% versus MLSS's -80. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — MLSS or SYK?

By beta (market sensitivity over 5 years), Stryker Corporation (SYK) is the lower-risk stock at 0.

52β versus Milestone Scientific Inc. 's 0. 85β — meaning MLSS is approximately 62% more volatile than SYK relative to the S&P 500. On balance sheet safety, Milestone Scientific Inc. (MLSS) carries a lower debt/equity ratio of 6% versus 66% for Stryker Corporation — giving it more financial flexibility in a downturn.

04

Which is growing faster — MLSS or SYK?

By revenue growth (latest reported year), Stryker Corporation (SYK) is pulling ahead at 11.

2% versus -12. 2% for Milestone Scientific Inc. (MLSS). On earnings-per-share growth, the picture is similar: Milestone Scientific Inc. grew EPS 37. 9% year-over-year, compared to 8. 2% for Stryker Corporation. Over a 3-year CAGR, SYK leads at 10. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — MLSS or SYK?

Stryker Corporation (SYK) is the more profitable company, earning 12.

9% net margin versus -54. 6% for Milestone Scientific Inc. — meaning it keeps 12. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: SYK leads at 19. 5% versus -78. 3% for MLSS. At the gross margin level — before operating expenses — MLSS leads at 74. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — MLSS or SYK?

In this comparison, SYK (1.

2% yield) pays a dividend. MLSS does not pay a meaningful dividend and should not be held primarily for income.

07

Is MLSS or SYK better for a retirement portfolio?

For long-horizon retirement investors, Stryker Corporation (SYK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

52), 1. 2% yield, +179. 2% 10Y return). Both have compounded well over 10 years (SYK: +179. 2%, MLSS: -80. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between MLSS and SYK?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

SYK pays a dividend while MLSS does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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MLSS

High-Growth Disruptor

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  • Market Cap > $100B
  • Revenue Growth > 12%
  • Gross Margin > 43%
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Stable Dividend Mega-Cap

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 7%
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