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NBTX vs NVCR vs NKTR vs IMVT
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Instruments & Supplies
Biotechnology
Biotechnology
NBTX vs NVCR vs NKTR vs IMVT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Medical - Instruments & Supplies | Biotechnology | Biotechnology |
| Market Cap | $2.06B | $1.92B | $1.69B | $5.53B |
| Revenue (TTM) | $48M | $674M | $55M | $0.00 |
| Net Income (TTM) | $-85M | $-173M | $-164M | $-464M |
| Gross Margin | 100.0% | 75.2% | 99.6% | — |
| Operating Margin | -143.9% | -27.2% | -237.9% | — |
| Total Debt | $51M | $290M | $149M | $98K |
| Cash & Equiv. | $50M | $103M | $15M | $714M |
NBTX vs NVCR vs NKTR vs IMVT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Dec 20 | May 26 | Return |
|---|---|---|---|
| Nanobiotix S.A. (NBTX) | 100 | 275.7 | +175.7% |
| NovoCure Limited (NVCR) | 100 | 10.3 | -89.7% |
| Nektar Therapeutics (NKTR) | 100 | 32.1 | -67.9% |
| Immunovant, Inc. (IMVT) | 100 | 62.7 | -37.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: NBTX vs NVCR vs NKTR vs IMVT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
NBTX is the clearest fit if your priority is momentum.
- +11.9% vs NVCR's +1.1%
NVCR carries the broadest edge in this set and is the clearest fit for growth exposure.
- Rev growth 8.3%, EPS growth 21.8%, 3Y rev CAGR 6.8%
- 8.3% revenue growth vs NBTX's -132.1%
- -16.5% ROA vs NBTX's -188.4%
NKTR lags the leaders in this set but could rank higher in a more targeted comparison.
IMVT is the #2 pick in this set and the best alternative if income & stability and long-term compounding is your priority.
- beta 1.37
- 173.6% 10Y total return vs NBTX's 150.9%
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- Beta 1.37, current ratio 11.16x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.3% revenue growth vs NBTX's -132.1% | |
| Quality / Margins | 3.2% margin vs NKTR's -297.1% | |
| Stability / Safety | Beta 1.37 vs NVCR's 2.20, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +11.9% vs NVCR's +1.1% | |
| Efficiency (ROA) | -16.5% ROA vs NBTX's -188.4% |
NBTX vs NVCR vs NKTR vs IMVT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
NBTX vs NVCR vs NKTR vs IMVT — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
NVCR leads in 1 of 6 categories
NBTX leads 1 • NKTR leads 0 • IMVT leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — NBTX and NVCR each lead in 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVCR and IMVT operate at a comparable scale, with $674M and $0 in trailing revenue. Profitability is closely matched — net margins range from -25.7% (NVCR) to -3.0% (NKTR). On growth, NBTX holds the edge at +186.8% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $48M | $674M | $55M | $0 |
| EBITDAEarnings before interest/tax | -$67M | -$165M | -$130M | -$487M |
| Net IncomeAfter-tax profit | -$85M | -$173M | -$164M | -$464M |
| Free Cash FlowCash after capex | -$33M | -$48M | -$209M | -$423M |
| Gross MarginGross profit ÷ Revenue | +100.0% | +75.2% | +99.6% | — |
| Operating MarginEBIT ÷ Revenue | -143.9% | -27.2% | -2.4% | — |
| Net MarginNet income ÷ Revenue | -177.5% | -25.7% | -3.0% | — |
| FCF MarginFCF ÷ Revenue | -69.2% | -7.1% | -3.8% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | +186.8% | +12.3% | -25.3% | — |
| EPS Growth (YoY)Latest quarter vs prior year | +76.1% | -100.0% | -4.5% | +19.7% |
Valuation Metrics
NVCR leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $2.1B | $1.9B | $1.7B | $5.5B |
| Enterprise ValueMkt cap + debt − cash | $2.1B | $2.1B | $1.8B | $4.8B |
| Trailing P/EPrice ÷ TTM EPS | -25.18x | -13.80x | -8.57x | -9.97x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 2.92x | 30.64x | — |
| Price / BookPrice ÷ Book value/share | — | 5.51x | 15.66x | 5.83x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
Evenly matched — NVCR and IMVT each lead in 4 of 9 comparable metrics.
Profitability & Efficiency
IMVT delivers a -47.1% return on equity — every $100 of shareholder capital generates $-47 in annual profit, vs $-4 for NKTR. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 1.66x. On the Piotroski fundamental quality scale (0–9), NVCR scores 5/9 vs NBTX's 1/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | — | -50.8% | -4.0% | -47.1% |
| ROA (TTM)Return on assets | -188.4% | -16.5% | -62.8% | -44.1% |
| ROICReturn on invested capital | — | -16.4% | -57.2% | — |
| ROCEReturn on capital employed | -2.6% | -28.9% | -55.7% | -66.1% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 5 | 2 | 2 |
| Debt / EquityFinancial leverage | — | 0.85x | 1.66x | 0.00x |
| Net DebtTotal debt minus cash | $1M | $187M | $134M | -$714M |
| Cash & Equiv.Liquid assets | $50M | $103M | $15M | $714M |
| Total DebtShort + long-term debt | $51M | $290M | $149M | $98,000 |
| Interest CoverageEBIT ÷ Interest expense | -3.83x | -96.80x | -4.74x | — |
Total Returns (Dividends Reinvested)
NBTX leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in NBTX five years ago would be worth $28,294 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, NBTX leads with a +1191.2% total return vs NVCR's +1.1%. The 3-year compound annual growth rate (CAGR) favors NBTX at 99.6% vs NVCR's -37.6% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +92.5% | +28.3% | +92.0% | +5.1% |
| 1-Year ReturnPast 12 months | +1191.2% | +1.1% | +818.2% | +96.1% |
| 3-Year ReturnCumulative with dividends | +695.0% | -75.7% | +621.8% | +40.9% |
| 5-Year ReturnCumulative with dividends | +182.9% | -91.3% | -72.3% | +62.4% |
| 10-Year ReturnCumulative with dividends | +150.9% | +30.3% | -59.1% | +173.6% |
| CAGR (3Y)Annualised 3-year return | +99.6% | -37.6% | +93.3% | +12.1% |
Risk & Volatility
Evenly matched — NBTX and IMVT each lead in 1 of 2 comparable metrics.
Risk & Volatility
IMVT is the less volatile stock with a 1.37 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NBTX currently trades 95.8% from its 52-week high vs NKTR's 76.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.09x | 2.15x | 1.80x | 1.36x |
| 52-Week HighHighest price in past year | $44.46 | $20.06 | $109.00 | $30.09 |
| 52-Week LowLowest price in past year | $3.26 | $9.82 | $7.99 | $13.36 |
| % of 52W HighCurrent price vs 52-week peak | +95.8% | +83.9% | +76.5% | +90.5% |
| RSI (14)Momentum oscillator 0–100 | 68.2 | 69.8 | 53.4 | 60.2 |
| Avg Volume (50D)Average daily shares traded | 75K | 1.5M | 991K | 1.4M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: NBTX as "Buy", NVCR as "Buy", NKTR as "Buy", IMVT as "Buy". Consensus price targets imply 99.0% upside for NVCR (target: $34) vs -34.3% for NBTX (target: $28).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $28.00 | $33.50 | $147.33 | $45.50 |
| # AnalystsCovering analysts | 3 | 15 | 33 | 23 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
NVCR leads in 1 of 6 categories (Valuation Metrics). NBTX leads in 1 (Total Returns). 3 tied.
NBTX vs NVCR vs NKTR vs IMVT: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is NBTX or NVCR or NKTR or IMVT a better buy right now?
For growth investors, NovoCure Limited (NVCR) is the stronger pick with 8.
3% revenue growth year-over-year, versus -132. 1% for Nanobiotix S. A. (NBTX). Analysts rate Nanobiotix S. A. (NBTX) a "Buy" — based on 3 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — NBTX or NVCR or NKTR or IMVT?
Over the past 5 years, Nanobiotix S.
A. (NBTX) delivered a total return of +182. 9%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: IMVT returned +190. 9% versus NKTR's -59. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — NBTX or NVCR or NKTR or IMVT?
By beta (market sensitivity over 5 years), Immunovant, Inc.
(IMVT) is the lower-risk stock at 1. 36β versus NovoCure Limited's 2. 15β — meaning NVCR is approximately 58% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 166% for Nektar Therapeutics — giving it more financial flexibility in a downturn.
04Which is growing faster — NBTX or NVCR or NKTR or IMVT?
By revenue growth (latest reported year), NovoCure Limited (NVCR) is pulling ahead at 8.
3% versus -132. 1% for Nanobiotix S. A. (NBTX). On earnings-per-share growth, the picture is similar: NovoCure Limited grew EPS 21. 8% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, NVCR leads at 6. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — NBTX or NVCR or NKTR or IMVT?
Nanobiotix S.
A. (NBTX) is the more profitable company, earning 586. 9% net margin versus -297. 1% for Nektar Therapeutics — meaning it keeps 586. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NBTX leads at 589. 1% versus -236. 8% for NKTR. At the gross margin level — before operating expenses — NBTX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — NBTX or NVCR or NKTR or IMVT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is NBTX or NVCR or NKTR or IMVT better for a retirement portfolio?
For long-horizon retirement investors, Immunovant, Inc.
(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+190. 9% 10Y return). NovoCure Limited (NVCR) carries a higher beta of 2. 15 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +190. 9%, NVCR: +38. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between NBTX and NVCR and NKTR and IMVT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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