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NERV logo
NERV
INVA logo
INVA
KO logo
KO
ABBV logo
ABBV
PFE logo
PFE
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Stock Comparison

NERV vs INVA vs KO vs ABBV vs PFE

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
NERV
Minerva Neurosciences, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$32M
5Y Perf.-84.4%
INVA
Innoviva, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.68B
5Y Perf.+62.7%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.61B
5Y Perf.+84.9%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$402.80B
5Y Perf.+132.0%
PFE
Pfizer Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$149.09B
5Y Perf.-15.5%

NERV vs INVA vs KO vs ABBV vs PFE — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
NERV logoNERV
INVA logoINVA
KO logoKO
ABBV logoABBV
PFE logoPFE
IndustryBiotechnologyBiotechnologyBeverages - Non-AlcoholicDrug Manufacturers - GeneralDrug Manufacturers - General
Market Cap$32M$1.68B$355.61B$402.80B$149.09B
Revenue (TTM)$0.00$424M$49.28B$61.16B$63.31B
Net Income (TTM)$-415M$504M$13.70B$4.23B$7.49B
Gross Margin76.2%61.7%70.2%69.3%
Operating Margin14.8%29.3%26.7%23.4%
Forward P/E6.4x25.3x16.0x8.9x
Total Debt$65M$269M$45.49B$69.07B$67.42B
Cash & Equiv.$82M$551M$10.27B$5.23B$1.14B

NERV vs INVA vs KO vs ABBV vs PFELong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

NERV
INVA
KO
ABBV
PFE
StockJun 20Jun 26Return
Minerva Neuroscienc… (NERV)10015.6-84.4%
Innoviva, Inc. (INVA)100162.7+62.7%
The Coca-Cola Compa… (KO)100184.9+84.9%
AbbVie Inc. (ABBV)100232.0+132.0%
Pfizer Inc. (PFE)10084.5-15.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: NERV vs INVA vs KO vs ABBV vs PFE

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: INVA leads in 4 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Minerva Neurosciences, Inc. is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. PFE also leads in specific categories worth noting. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇INVA emerged as the overall leader. Track its performance:
NERV
Minerva Neurosciences, Inc.
The Growth Leader

NERV is the #2 pick in this set and the best alternative if growth and momentum is your priority.

  • 121.0% revenue growth vs PFE's -1.6%
  • +152.0% vs INVA's +6.3%
Best for: growth and momentum
INVA
Innoviva, Inc.
The Growth Play

INVA carries the broadest edge in this set and is the clearest fit for growth exposure and sleep-well-at-night.

  • Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
  • Lower volatility, beta 0.06, Low D/E 22.9%, current ratio 14.64x
  • PEG 0.62 vs KO's 2.26
  • Beta 0.06, current ratio 14.64x
Best for: growth exposure and sleep-well-at-night
KO
The Coca-Cola Company
The Income Angle

KO lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: consumer defensive exposure
ABBV
AbbVie Inc.
The Income Pick

ABBV is the clearest fit if your priority is income & stability and long-term compounding.

  • Dividend streak 43 yrs, beta 0.14, yield 2.9%
  • 362.2% 10Y total return vs KO's 121.1%
Best for: income & stability and long-term compounding
PFE
Pfizer Inc.
The Income Pick

PFE ranks third and is worth considering specifically for dividends.

  • 6.6% yield, 15-year raise streak, vs KO's 2.5%, (2 stocks pay no dividend)
Best for: dividends
See the full category breakdown
CategoryWinnerWhy
GrowthNERV logoNERV121.0% revenue growth vs PFE's -1.6%
ValueINVA logoINVALower P/E (6.4x vs 8.9x)
Quality / MarginsINVA logoINVA118.9% margin vs ABBV's 6.9%
Stability / SafetyINVA logoINVABeta 0.06 vs NERV's 1.28
DividendsPFE logoPFE6.6% yield, 15-year raise streak, vs KO's 2.5%, (2 stocks pay no dividend)
Momentum (1Y)NERV logoNERV+152.0% vs INVA's +6.3%
Efficiency (ROA)INVA logoINVA32.4% ROA vs NERV's -6.6%

NERV vs INVA vs KO vs ABBV vs PFE — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

Discover the Biotech & Healthcare Stocks Theme

These companies are key players in the Biotech & Healthcare Stocks ecosystem. See how they stack up against the rest of the sector.

Explore Theme
NERVMinerva Neurosciences, Inc.

Segment breakdown not available.

INVAInnoviva, Inc.
FY 2025
Royalty
57.5%$236M
Product
41.8%$172M
License And Other Revenue
0.7%$3M
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B
ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B
PFEPfizer Inc.
FY 2025
Biopharma Segment
97.8%$61.2B
Segment Reporting, Reconciling Item, Corporate Nonsegment
2.2%$1.4B

NERV vs INVA vs KO vs ABBV vs PFE — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLINVALAGGINGPFE

Income & Cash Flow (Last 12 Months)

INVA leads this category, winning 3 of 6 comparable metrics.

PFE and NERV operate at a comparable scale, with $63.3B and $0 in trailing revenue. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to ABBV's 6.9%. On growth, KO holds the edge at +12.1% YoY revenue growth, suggesting stronger near-term business momentum.

MetricNERV logoNERVMinerva Neuroscie…INVA logoINVAInnoviva, Inc.KO logoKOThe Coca-Cola Com…ABBV logoABBVAbbVie Inc.PFE logoPFEPfizer Inc.
RevenueTrailing 12 months$0$424M$49.3B$61.2B$63.3B
EBITDAEarnings before interest/tax-$28M$86M$15.5B$24.5B$21.0B
Net IncomeAfter-tax profit-$415M$504M$13.7B$4.2B$7.5B
Free Cash FlowCash after capex-$5.4B$181M$12.6B$18.7B$9.5B
Gross MarginGross profit ÷ Revenue+76.2%+61.7%+70.2%+69.3%
Operating MarginEBIT ÷ Revenue+14.8%+29.3%+26.7%+23.4%
Net MarginNet income ÷ Revenue+118.9%+27.8%+6.9%+11.8%
FCF MarginFCF ÷ Revenue+42.6%+25.5%+30.6%+15.0%
Rev. Growth (YoY)Latest quarter vs prior year+10.6%+12.1%+10.0%+5.4%
EPS Growth (YoY)Latest quarter vs prior year+4.0%+18.2%+57.4%-9.5%
INVA leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

INVA leads this category, winning 5 of 7 comparable metrics.

At 6.9x trailing earnings, INVA trades at a 93% valuation discount to ABBV's 96.1x P/E. Adjusting for growth (PEG ratio), INVA offers better value at 0.67x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.

MetricNERV logoNERVMinerva Neuroscie…INVA logoINVAInnoviva, Inc.KO logoKOThe Coca-Cola Com…ABBV logoABBVAbbVie Inc.PFE logoPFEPfizer Inc.
Market CapShares × price$32M$1.7B$355.6B$402.8B$149.1B
Enterprise ValueMkt cap + debt − cash$14M$1.4B$390.8B$466.6B$215.4B
Trailing P/EPrice ÷ TTM EPS-0.13x6.89x27.18x96.09x19.27x
Forward P/EPrice ÷ next-FY EPS est.6.36x25.27x15.96x8.85x
PEG RatioP/E ÷ EPS growth rate0.67x2.43x
EV / EBITDAEnterprise value multiple6.85x26.39x16.53x10.59x
Price / SalesMarket cap ÷ Revenue3.95x7.42x6.59x2.38x
Price / BookPrice ÷ Book value/share1.64x10.40x1.72x
Price / FCFMarket cap ÷ FCF8.57x67.15x22.61x16.43x
INVA leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

INVA leads this category, winning 4 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $8 for PFE. INVA carries lower financial leverage with a 0.23x debt-to-equity ratio, signaling a more conservative balance sheet compared to KO's 1.33x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs NERV's 2/9, reflecting strong financial health.

MetricNERV logoNERVMinerva Neuroscie…INVA logoINVAInnoviva, Inc.KO logoKOThe Coca-Cola Com…ABBV logoABBVAbbVie Inc.PFE logoPFEPfizer Inc.
ROE (TTM)Return on equity+47.6%+41.1%+62.1%+8.3%
ROA (TTM)Return on assets-6.6%+32.4%+13.1%+3.1%+3.6%
ROICReturn on invested capital+14.2%+15.8%+23.9%+7.5%
ROCEReturn on capital employed-23.2%+12.4%+17.3%+21.5%+9.0%
Piotroski ScoreFundamental quality 0–925767
Debt / EquityFinancial leverage0.23x1.33x0.78x
Net DebtTotal debt minus cash-$17M-$282M$35.2B$63.8B$66.3B
Cash & Equiv.Liquid assets$82M$551M$10.3B$5.2B$1.1B
Total DebtShort + long-term debt$65M$269M$45.5B$69.1B$67.4B
Interest CoverageEBIT ÷ Interest expense63.45x10.70x3.28x4.02x
INVA leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ABBV leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in ABBV five years ago would be worth $22,367 today (with dividends reinvested), compared to $1,905 for NERV. Over the past 12 months, NERV leads with a +152.0% total return vs INVA's +6.3%. The 3-year compound annual growth rate (CAGR) favors ABBV at 21.5% vs NERV's -12.1% — a key indicator of consistent wealth creation.

MetricNERV logoNERVMinerva Neuroscie…INVA logoINVAInnoviva, Inc.KO logoKOThe Coca-Cola Com…ABBV logoABBVAbbVie Inc.PFE logoPFEPfizer Inc.
YTD ReturnYear-to-date+15.1%+14.4%+20.3%+0.8%+7.5%
1-Year ReturnPast 12 months+152.0%+6.3%+17.2%+21.9%+12.4%
3-Year ReturnCumulative with dividends-32.2%+69.7%+47.0%+79.3%-21.6%
5-Year ReturnCumulative with dividends-81.0%+77.9%+65.6%+123.7%-13.0%
10-Year ReturnCumulative with dividends-94.4%+108.1%+121.1%+362.2%+25.8%
CAGR (3Y)Annualised 3-year return-12.1%+19.3%+13.7%+21.5%-7.8%
ABBV leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

KO leads this category, winning 2 of 2 comparable metrics.

KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than NERV's 1.28 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs NERV's 36.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricNERV logoNERVMinerva Neuroscie…INVA logoINVAInnoviva, Inc.KO logoKOThe Coca-Cola Com…ABBV logoABBVAbbVie Inc.PFE logoPFEPfizer Inc.
Beta (5Y)Sensitivity to S&P 5001.28x0.06x-0.20x0.14x0.38x
52-Week HighHighest price in past year$12.46$25.15$84.04$244.81$28.75
52-Week LowLowest price in past year$1.57$16.52$65.35$181.73$23.11
% of 52W HighCurrent price vs 52-week peak+36.2%+90.4%+98.3%+93.0%+91.2%
RSI (14)Momentum oscillator 0–10037.450.660.662.853.2
Avg Volume (50D)Average daily shares traded154K660K12.7M4.6M28.5M
KO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — KO and PFE each lead in 1 of 2 comparable metrics.

Analyst consensus: NERV as "Buy", INVA as "Buy", KO as "Buy", ABBV as "Buy", PFE as "Hold". Consensus price targets imply 75.9% upside for INVA (target: $40) vs 2.1% for PFE (target: $27). For income investors, PFE offers the higher dividend yield at 6.56% vs KO's 2.46%.

MetricNERV logoNERVMinerva Neuroscie…INVA logoINVAInnoviva, Inc.KO logoKOThe Coca-Cola Com…ABBV logoABBVAbbVie Inc.PFE logoPFEPfizer Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyHold
Price TargetConsensus 12-month target$5.00$40.00$86.13$256.92$26.75
# AnalystsCovering analysts710484139
Dividend YieldAnnual dividend ÷ price+2.5%+2.9%+6.6%
Dividend StreakConsecutive years of raises2564315
Dividend / ShareAnnual DPS$2.04$6.57$1.72
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.3%+0.2%+0.2%0.0%
Evenly matched — KO and PFE each lead in 1 of 2 comparable metrics.
Key Takeaway

INVA leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). ABBV leads in 1 (Total Returns). 1 tied.

Best OverallInnoviva, Inc. (INVA)Leads 3 of 6 categories
Loading custom metrics...

NERV vs INVA vs KO vs ABBV vs PFE: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is NERV or INVA or KO or ABBV or PFE a better buy right now?

For growth investors, Innoviva, Inc.

(INVA) is the stronger pick with 18. 5% revenue growth year-over-year, versus -1. 6% for Pfizer Inc. (PFE). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (6. 4x forward), making it the more compelling value choice. Analysts rate Minerva Neurosciences, Inc. (NERV) a "Buy" — based on 7 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — NERV or INVA or KO or ABBV or PFE?

On trailing P/E, Innoviva, Inc.

(INVA) is the cheapest at 6. 9x versus AbbVie Inc. at 96. 1x. On forward P/E, Innoviva, Inc. is actually cheaper at 6. 4x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Innoviva, Inc. wins at 0. 62x versus The Coca-Cola Company's 2. 26x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — NERV or INVA or KO or ABBV or PFE?

Over the past 5 years, AbbVie Inc.

(ABBV) delivered a total return of +123. 7%, compared to -81. 0% for Minerva Neurosciences, Inc. (NERV). Over 10 years, the gap is even starker: ABBV returned +362. 2% versus NERV's -94. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — NERV or INVA or KO or ABBV or PFE?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

20β versus Minerva Neurosciences, Inc. 's 1. 28β — meaning NERV is approximately -738% more volatile than KO relative to the S&P 500. On balance sheet safety, Innoviva, Inc. (INVA) carries a lower debt/equity ratio of 23% versus 133% for The Coca-Cola Company — giving it more financial flexibility in a downturn.

05

Which is growing faster — NERV or INVA or KO or ABBV or PFE?

By revenue growth (latest reported year), Innoviva, Inc.

(INVA) is pulling ahead at 18. 5% versus -1. 6% for Pfizer Inc. (PFE). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -183. 5% for Minerva Neurosciences, Inc.. Over a 3-year CAGR, INVA leads at 8. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — NERV or INVA or KO or ABBV or PFE?

Innoviva, Inc.

(INVA) is the more profitable company, earning 63. 8% net margin versus 0. 0% for Minerva Neurosciences, Inc. — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus 0. 0% for NERV. At the gross margin level — before operating expenses — INVA leads at 72. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is NERV or INVA or KO or ABBV or PFE more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Innoviva, Inc. (INVA) is the more undervalued stock at a PEG of 0. 62x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Innoviva, Inc. (INVA) trades at 6. 4x forward P/E versus 25. 3x for The Coca-Cola Company — 18. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for INVA: 75. 9% to $40. 00.

08

Which pays a better dividend — NERV or INVA or KO or ABBV or PFE?

In this comparison, PFE (6.

6% yield), ABBV (2. 9% yield), KO (2. 5% yield) pay a dividend. NERV, INVA do not pay a meaningful dividend and should not be held primarily for income.

09

Is NERV or INVA or KO or ABBV or PFE better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

20), 2. 5% yield, +121. 1% 10Y return). Both have compounded well over 10 years (KO: +121. 1%, NERV: -94. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between NERV and INVA and KO and ABBV and PFE?

These companies operate in different sectors (NERV (Healthcare) and INVA (Healthcare) and KO (Consumer Defensive) and ABBV (Healthcare) and PFE (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: NERV is a small-cap quality compounder stock; INVA is a small-cap high-growth stock; KO is a large-cap quality compounder stock; ABBV is a large-cap quality compounder stock; PFE is a mid-cap income-oriented stock. KO, ABBV, PFE pay a dividend while NERV, INVA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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