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Stock Comparison

PFE vs JNJ

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
PFE
Pfizer Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$150.40B
5Y Perf.-27.0%
JNJ
Johnson & Johnson

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$543.64B
5Y Perf.+51.7%

PFE vs JNJ — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
PFE logoPFE
JNJ logoJNJ
IndustryDrug Manufacturers - GeneralDrug Manufacturers - General
Market Cap$150.40B$543.64B
Revenue (TTM)$63.31B$92.15B
Net Income (TTM)$7.49B$25.12B
Gross Margin69.3%68.1%
Operating Margin23.4%26.1%
Forward P/E8.9x19.5x
Total Debt$67.42B$36.63B
Cash & Equiv.$1.14B$24.11B

PFE vs JNJLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

PFE
JNJ
StockMay 20May 26Return
Pfizer Inc. (PFE)10073.0-27.0%
Johnson & Johnson (JNJ)100151.7+51.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: PFE vs JNJ

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: JNJ leads in 5 of 7 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Pfizer Inc. is the stronger pick specifically for valuation and capital efficiency and dividend income and shareholder returns. As sector peers, any of these can serve as alternatives in the same allocation.
PFE
Pfizer Inc.
The Defensive Pick

PFE is the clearest fit if your priority is defensive.

  • Beta 0.54, yield 6.5%, current ratio 1.16x
  • Lower P/E (8.9x vs 19.5x)
  • 6.5% yield, 15-year raise streak, vs JNJ's 2.2%
Best for: defensive
JNJ
Johnson & Johnson
The Income Pick

JNJ carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 36 yrs, beta 0.06, yield 2.2%
  • Rev growth 4.3%, EPS growth -57.8%, 3Y rev CAGR 4.1%
  • 136.8% 10Y total return vs PFE's 30.5%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthJNJ logoJNJ4.3% revenue growth vs PFE's -1.6%
ValuePFE logoPFELower P/E (8.9x vs 19.5x)
Quality / MarginsJNJ logoJNJ27.3% margin vs PFE's 11.8%
Stability / SafetyJNJ logoJNJBeta 0.06 vs PFE's 0.54, lower leverage
DividendsPFE logoPFE6.5% yield, 15-year raise streak, vs JNJ's 2.2%
Momentum (1Y)JNJ logoJNJ+48.9% vs PFE's +18.0%
Efficiency (ROA)JNJ logoJNJ13.0% ROA vs PFE's 3.6%, ROIC 20.7% vs 7.5%

PFE vs JNJ — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

PFEPfizer Inc.
FY 2025
Biopharma Segment
100.0%$61.2B
JNJJohnson & Johnson
FY 2024
Innovative Medicine
64.1%$57.0B
MedTech
35.9%$31.9B

PFE vs JNJ — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLJNJLAGGINGPFE

Income & Cash Flow (Last 12 Months)

JNJ leads this category, winning 5 of 6 comparable metrics.

JNJ and PFE operate at a comparable scale, with $92.1B and $63.3B in trailing revenue. JNJ is the more profitable business, keeping 27.3% of every revenue dollar as net income compared to PFE's 11.8%.

MetricPFE logoPFEPfizer Inc.JNJ logoJNJJohnson & Johnson
RevenueTrailing 12 months$63.3B$92.1B
EBITDAEarnings before interest/tax$21.0B$31.4B
Net IncomeAfter-tax profit$7.5B$25.1B
Free Cash FlowCash after capex$9.5B$19.1B
Gross MarginGross profit ÷ Revenue+69.3%+68.1%
Operating MarginEBIT ÷ Revenue+23.4%+26.1%
Net MarginNet income ÷ Revenue+11.8%+27.3%
FCF MarginFCF ÷ Revenue+15.0%+20.7%
Rev. Growth (YoY)Latest quarter vs prior year+5.4%+6.8%
EPS Growth (YoY)Latest quarter vs prior year-9.5%+91.0%
JNJ leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

PFE leads this category, winning 6 of 6 comparable metrics.

At 19.4x trailing earnings, PFE trades at a 50% valuation discount to JNJ's 39.0x P/E. On an enterprise value basis, PFE's 10.7x EV/EBITDA is more attractive than JNJ's 18.9x.

MetricPFE logoPFEPfizer Inc.JNJ logoJNJJohnson & Johnson
Market CapShares × price$150.4B$543.6B
Enterprise ValueMkt cap + debt − cash$216.7B$556.2B
Trailing P/EPrice ÷ TTM EPS19.44x38.96x
Forward P/EPrice ÷ next-FY EPS est.8.93x19.47x
PEG RatioP/E ÷ EPS growth rate34.64x
EV / EBITDAEnterprise value multiple10.65x18.86x
Price / SalesMarket cap ÷ Revenue2.40x6.12x
Price / BookPrice ÷ Book value/share1.73x7.67x
Price / FCFMarket cap ÷ FCF16.57x27.40x
PFE leads this category, winning 6 of 6 comparable metrics.

Profitability & Efficiency

JNJ leads this category, winning 8 of 9 comparable metrics.

JNJ delivers a 31.7% return on equity — every $100 of shareholder capital generates $32 in annual profit, vs $8 for PFE. JNJ carries lower financial leverage with a 0.51x debt-to-equity ratio, signaling a more conservative balance sheet compared to PFE's 0.78x. On the Piotroski fundamental quality scale (0–9), PFE scores 7/9 vs JNJ's 5/9, reflecting strong financial health.

MetricPFE logoPFEPfizer Inc.JNJ logoJNJJohnson & Johnson
ROE (TTM)Return on equity+8.3%+31.7%
ROA (TTM)Return on assets+3.6%+13.0%
ROICReturn on invested capital+7.5%+20.7%
ROCEReturn on capital employed+9.0%+17.6%
Piotroski ScoreFundamental quality 0–975
Debt / EquityFinancial leverage0.78x0.51x
Net DebtTotal debt minus cash$66.3B$12.5B
Cash & Equiv.Liquid assets$1.1B$24.1B
Total DebtShort + long-term debt$67.4B$36.6B
Interest CoverageEBIT ÷ Interest expense4.02x48.23x
JNJ leads this category, winning 8 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

JNJ leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in JNJ five years ago would be worth $14,920 today (with dividends reinvested), compared to $8,677 for PFE. Over the past 12 months, JNJ leads with a +48.9% total return vs PFE's +18.0%. The 3-year compound annual growth rate (CAGR) favors JNJ at 13.9% vs PFE's -6.5% — a key indicator of consistent wealth creation.

MetricPFE logoPFEPfizer Inc.JNJ logoJNJJohnson & Johnson
YTD ReturnYear-to-date+6.7%+9.4%
1-Year ReturnPast 12 months+18.0%+48.9%
3-Year ReturnCumulative with dividends-18.2%+47.8%
5-Year ReturnCumulative with dividends-13.2%+49.2%
10-Year ReturnCumulative with dividends+30.5%+136.8%
CAGR (3Y)Annualised 3-year return-6.5%+13.9%
JNJ leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

Evenly matched — PFE and JNJ each lead in 1 of 2 comparable metrics.

JNJ is the less volatile stock with a 0.06 beta — it tends to amplify market swings less than PFE's 0.54 beta. A beta below 1.0 means the stock typically moves less than the S&P 500.

MetricPFE logoPFEPfizer Inc.JNJ logoJNJJohnson & Johnson
Beta (5Y)Sensitivity to S&P 5000.54x0.06x
52-Week HighHighest price in past year$28.75$251.71
52-Week LowLowest price in past year$21.97$146.12
% of 52W HighCurrent price vs 52-week peak+92.0%+89.6%
RSI (14)Momentum oscillator 0–10041.435.3
Avg Volume (50D)Average daily shares traded33.1M7.0M
Evenly matched — PFE and JNJ each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — PFE and JNJ each lead in 1 of 2 comparable metrics.

Wall Street rates PFE as "Hold" and JNJ as "Buy". Consensus price targets imply 10.5% upside for JNJ (target: $249) vs 3.1% for PFE (target: $27). For income investors, PFE offers the higher dividend yield at 6.50% vs JNJ's 2.16%.

MetricPFE logoPFEPfizer Inc.JNJ logoJNJJohnson & Johnson
Analyst RatingConsensus buy/hold/sellHoldBuy
Price TargetConsensus 12-month target$27.27$249.27
# AnalystsCovering analysts3940
Dividend YieldAnnual dividend ÷ price+6.5%+2.2%
Dividend StreakConsecutive years of raises1536
Dividend / ShareAnnual DPS$1.72$4.87
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.4%
Evenly matched — PFE and JNJ each lead in 1 of 2 comparable metrics.
Key Takeaway

JNJ leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PFE leads in 1 (Valuation Metrics). 2 tied.

Best OverallJohnson & Johnson (JNJ)Leads 3 of 6 categories
Loading custom metrics...

PFE vs JNJ: Frequently Asked Questions

10 questions · data-driven answers · updated daily

01

Is PFE or JNJ a better buy right now?

For growth investors, Johnson & Johnson (JNJ) is the stronger pick with 4.

3% revenue growth year-over-year, versus -1. 6% for Pfizer Inc. (PFE). Pfizer Inc. (PFE) offers the better valuation at 19. 4x trailing P/E (8. 9x forward), making it the more compelling value choice. Analysts rate Johnson & Johnson (JNJ) a "Buy" — based on 40 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — PFE or JNJ?

On trailing P/E, Pfizer Inc.

(PFE) is the cheapest at 19. 4x versus Johnson & Johnson at 39. 0x. On forward P/E, Pfizer Inc. is actually cheaper at 8. 9x.

03

Which is the better long-term investment — PFE or JNJ?

Over the past 5 years, Johnson & Johnson (JNJ) delivered a total return of +49.

2%, compared to -13. 2% for Pfizer Inc. (PFE). Over 10 years, the gap is even starker: JNJ returned +136. 8% versus PFE's +30. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — PFE or JNJ?

By beta (market sensitivity over 5 years), Johnson & Johnson (JNJ) is the lower-risk stock at 0.

06β versus Pfizer Inc. 's 0. 54β — meaning PFE is approximately 854% more volatile than JNJ relative to the S&P 500. On balance sheet safety, Johnson & Johnson (JNJ) carries a lower debt/equity ratio of 51% versus 78% for Pfizer Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — PFE or JNJ?

By revenue growth (latest reported year), Johnson & Johnson (JNJ) is pulling ahead at 4.

3% versus -1. 6% for Pfizer Inc. (PFE). On earnings-per-share growth, the picture is similar: Pfizer Inc. grew EPS -3. 5% year-over-year, compared to -57. 8% for Johnson & Johnson. Over a 3-year CAGR, JNJ leads at 4. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — PFE or JNJ?

Johnson & Johnson (JNJ) is the more profitable company, earning 15.

8% net margin versus 12. 4% for Pfizer Inc. — meaning it keeps 15. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: JNJ leads at 24. 9% versus 24. 7% for PFE. At the gross margin level — before operating expenses — PFE leads at 70. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is PFE or JNJ more undervalued right now?

On forward earnings alone, Pfizer Inc.

(PFE) trades at 8. 9x forward P/E versus 19. 5x for Johnson & Johnson — 10. 5x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for JNJ: 10. 5% to $249. 27.

08

Which pays a better dividend — PFE or JNJ?

All stocks in this comparison pay dividends.

Pfizer Inc. (PFE) offers the highest yield at 6. 5%, versus 2. 2% for Johnson & Johnson (JNJ).

09

Is PFE or JNJ better for a retirement portfolio?

For long-horizon retirement investors, Johnson & Johnson (JNJ) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

06), 2. 2% yield, +136. 8% 10Y return). Both have compounded well over 10 years (JNJ: +136. 8%, PFE: +30. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between PFE and JNJ?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: PFE is a mid-cap income-oriented stock; JNJ is a large-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform both.

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PFE

Income & Dividend Stock

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 7%
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JNJ

Dividend Mega-Cap Quality

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 16%
Run This Screen
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Beat Both

Find stocks that outperform PFE and JNJ on the metrics below

Revenue Growth>
%
(PFE: 5.4% · JNJ: 6.8%)
Net Margin>
%
(PFE: 11.8% · JNJ: 27.3%)
P/E Ratio<
x
(PFE: 19.4x · JNJ: 39.0x)

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