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Stock Comparison

NNOX vs ATEC vs SYK vs ISRG

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
NNOX
Nano-X Imaging Ltd.

Medical - Devices

HealthcareNASDAQ • IL
Market Cap$113M
5Y Perf.-96.2%
ATEC
Alphatec Holdings, Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$1.14B
5Y Perf.-48.2%
SYK
Stryker Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$109.33B
5Y Perf.+16.5%
ISRG
Intuitive Surgical, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$159.85B
5Y Perf.+65.0%

NNOX vs ATEC vs SYK vs ISRG — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
NNOX logoNNOX
ATEC logoATEC
SYK logoSYK
ISRG logoISRG
IndustryMedical - DevicesMedical - DevicesMedical - DevicesMedical - Instruments & Supplies
Market Cap$113M$1.14B$109.33B$159.85B
Revenue (TTM)$12M$595M$25.12B$10.58B
Net Income (TTM)$-56M$-125M$3.25B$2.98B
Gross Margin-98.8%89.6%63.5%66.3%
Operating Margin-469.7%-9.6%22.4%30.5%
Forward P/E24.1x19.1x43.3x
Total Debt$7M$620M$14.86B$303M
Cash & Equiv.$39M$161M$4.01B$3.37B

NNOX vs ATEC vs SYK vs ISRGLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

NNOX
ATEC
SYK
ISRG
StockDec 20May 26Return
Nano-X Imaging Ltd. (NNOX)1003.8-96.2%
Alphatec Holdings, … (ATEC)10051.8-48.2%
Stryker Corporation (SYK)100116.5+16.5%
Intuitive Surgical,… (ISRG)100165.0+65.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: NNOX vs ATEC vs SYK vs ISRG

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: SYK and ISRG are tied at the top with 3 categories each — the right choice depends on your priorities. Intuitive Surgical, Inc. is the stronger pick specifically for profitability and margin quality and recent price momentum and sentiment. ATEC also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
NNOX
Nano-X Imaging Ltd.
The Secondary Option

NNOX lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
ATEC
Alphatec Holdings, Inc.
The Growth Play

ATEC is the clearest fit if your priority is growth exposure.

  • Rev growth 25.0%, EPS growth 15.0%, 3Y rev CAGR 29.6%
  • 25.0% revenue growth vs SYK's 11.2%
Best for: growth exposure
SYK
Stryker Corporation
The Income Pick

SYK carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.

  • Dividend streak 34 yrs, beta 0.52, yield 1.2%
  • Lower volatility, beta 0.52, Low D/E 66.3%, current ratio 1.89x
  • PEG 1.28 vs ISRG's 1.99
  • Beta 0.52, yield 1.2%, current ratio 1.89x
Best for: income & stability and sleep-well-at-night
ISRG
Intuitive Surgical, Inc.
The Long-Run Compounder

ISRG is the #2 pick in this set and the best alternative if long-term compounding is your priority.

  • 5.5% 10Y total return vs ATEC's 215.7%
  • 28.2% margin vs NNOX's -452.8%
  • -16.4% vs NNOX's -66.6%
  • 14.8% ROA vs NNOX's -31.6%, ROIC 15.0% vs -27.9%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthATEC logoATEC25.0% revenue growth vs SYK's 11.2%
ValueSYK logoSYKLower P/E (19.1x vs 43.3x), PEG 1.28 vs 1.99
Quality / MarginsISRG logoISRG28.2% margin vs NNOX's -452.8%
Stability / SafetySYK logoSYKBeta 0.52 vs NNOX's 1.75
DividendsSYK logoSYK1.2% yield; 34-year raise streak; the other 3 pay no meaningful dividend
Momentum (1Y)ISRG logoISRG-16.4% vs NNOX's -66.6%
Efficiency (ROA)ISRG logoISRG14.8% ROA vs NNOX's -31.6%, ROIC 15.0% vs -27.9%

NNOX vs ATEC vs SYK vs ISRG — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

NNOXNano-X Imaging Ltd.

Segment breakdown not available.

ATECAlphatec Holdings, Inc.
FY 2025
Products And Services
100.0%$764M
SYKStryker Corporation
FY 2025
MedSurg
62.3%$15.6B
Orthopaedics
37.7%$9.5B
ISRGIntuitive Surgical, Inc.
FY 2025
Instruments and Accessories
59.8%$6.0B
Systems
24.6%$2.5B
Services
15.6%$1.6B

NNOX vs ATEC vs SYK vs ISRG — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLISRGLAGGINGATEC

Income & Cash Flow (Last 12 Months)

ISRG leads this category, winning 4 of 6 comparable metrics.

SYK is the larger business by revenue, generating $25.1B annually — 2041.6x NNOX's $12M. ISRG is the more profitable business, keeping 28.2% of every revenue dollar as net income compared to NNOX's -4.5%. On growth, ISRG holds the edge at +23.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricNNOX logoNNOXNano-X Imaging Lt…ATEC logoATECAlphatec Holdings…SYK logoSYKStryker Corporati…ISRG logoISRGIntuitive Surgica…
RevenueTrailing 12 months$12M$595M$25.1B$10.6B
EBITDAEarnings before interest/tax-$46M$4M$6.3B$3.8B
Net IncomeAfter-tax profit-$56M-$125M$3.2B$3.0B
Free Cash FlowCash after capex-$47M$7M$4.3B$2.8B
Gross MarginGross profit ÷ Revenue-98.8%+89.6%+63.5%+66.3%
Operating MarginEBIT ÷ Revenue-4.7%-9.6%+22.4%+30.5%
Net MarginNet income ÷ Revenue-4.5%-21.1%+12.9%+28.2%
FCF MarginFCF ÷ Revenue-3.8%+1.2%+17.1%+26.8%
Rev. Growth (YoY)Latest quarter vs prior year+13.7%-100.0%+11.4%+23.0%
EPS Growth (YoY)Latest quarter vs prior year+8.7%+37.1%+56.0%+18.8%
ISRG leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

SYK leads this category, winning 4 of 7 comparable metrics.

At 34.0x trailing earnings, SYK trades at a 41% valuation discount to ISRG's 57.2x P/E. Adjusting for growth (PEG ratio), SYK offers better value at 2.29x vs ISRG's 2.63x — a lower PEG means you pay less per unit of expected earnings growth.

MetricNNOX logoNNOXNano-X Imaging Lt…ATEC logoATECAlphatec Holdings…SYK logoSYKStryker Corporati…ISRG logoISRGIntuitive Surgica…
Market CapShares × price$113M$1.1B$109.3B$159.8B
Enterprise ValueMkt cap + debt − cash$81M$1.6B$120.2B$156.8B
Trailing P/EPrice ÷ TTM EPS-1.90x-7.83x33.98x57.19x
Forward P/EPrice ÷ next-FY EPS est.24.13x19.06x43.35x
PEG RatioP/E ÷ EPS growth rate2.29x2.63x
EV / EBITDAEnterprise value multiple3672.06x19.76x43.28x
Price / SalesMarket cap ÷ Revenue10.03x1.49x4.35x15.88x
Price / BookPrice ÷ Book value/share0.54x31.32x4.87x9.10x
Price / FCFMarket cap ÷ FCF410.02x25.53x64.18x
SYK leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

ISRG leads this category, winning 7 of 9 comparable metrics.

ISRG delivers a 16.9% return on equity — every $100 of shareholder capital generates $17 in annual profit, vs $-4 for ATEC. ISRG carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to ATEC's 17.21x. On the Piotroski fundamental quality scale (0–9), ATEC scores 6/9 vs NNOX's 4/9, reflecting solid financial health.

MetricNNOX logoNNOXNano-X Imaging Lt…ATEC logoATECAlphatec Holdings…SYK logoSYKStryker Corporati…ISRG logoISRGIntuitive Surgica…
ROE (TTM)Return on equity-35.5%-4.4%+15.0%+16.9%
ROA (TTM)Return on assets-31.6%-15.8%+6.9%+14.8%
ROICReturn on invested capital-27.9%-12.6%+11.4%+15.0%
ROCEReturn on capital employed-28.4%-13.7%+13.0%+16.5%
Piotroski ScoreFundamental quality 0–94666
Debt / EquityFinancial leverage0.04x17.21x0.66x0.02x
Net DebtTotal debt minus cash-$32M$459M$10.8B-$3.1B
Cash & Equiv.Liquid assets$39M$161M$4.0B$3.4B
Total DebtShort + long-term debt$7M$620M$14.9B$303M
Interest CoverageEBIT ÷ Interest expense-379.29x-3.29x6.72x
ISRG leads this category, winning 7 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ISRG leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in ISRG five years ago would be worth $16,174 today (with dividends reinvested), compared to $661 for NNOX. Over the past 12 months, ISRG leads with a -16.4% total return vs NNOX's -66.6%. The 3-year compound annual growth rate (CAGR) favors ISRG at 14.1% vs NNOX's -52.7% — a key indicator of consistent wealth creation.

MetricNNOX logoNNOXNano-X Imaging Lt…ATEC logoATECAlphatec Holdings…SYK logoSYKStryker Corporati…ISRG logoISRGIntuitive Surgica…
YTD ReturnYear-to-date-38.9%-63.8%-17.8%-19.9%
1-Year ReturnPast 12 months-66.6%-41.0%-24.5%-16.4%
3-Year ReturnCumulative with dividends-89.4%-49.4%+2.4%+48.5%
5-Year ReturnCumulative with dividends-93.4%-46.4%+17.5%+61.7%
10-Year ReturnCumulative with dividends-96.1%+215.7%+179.2%+549.2%
CAGR (3Y)Annualised 3-year return-52.7%-20.3%+0.8%+14.1%
ISRG leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — SYK and ISRG each lead in 1 of 2 comparable metrics.

SYK is the less volatile stock with a 0.52 beta — it tends to amplify market swings less than NNOX's 1.75 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ISRG currently trades 74.5% from its 52-week high vs NNOX's 29.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricNNOX logoNNOXNano-X Imaging Lt…ATEC logoATECAlphatec Holdings…SYK logoSYKStryker Corporati…ISRG logoISRGIntuitive Surgica…
Beta (5Y)Sensitivity to S&P 5001.75x0.74x0.52x1.00x
52-Week HighHighest price in past year$5.86$23.29$404.87$603.88
52-Week LowLowest price in past year$1.66$6.85$284.97$427.84
% of 52W HighCurrent price vs 52-week peak+29.5%+32.3%+70.5%+74.5%
RSI (14)Momentum oscillator 0–10037.633.426.643.6
Avg Volume (50D)Average daily shares traded1.4M3.1M2.1M1.8M
Evenly matched — SYK and ISRG each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: NNOX as "Buy", ATEC as "Buy", SYK as "Buy", ISRG as "Buy". Consensus price targets imply 940.5% upside for NNOX (target: $18) vs 36.5% for SYK (target: $390). SYK is the only dividend payer here at 1.18% yield — a key consideration for income-focused portfolios.

MetricNNOX logoNNOXNano-X Imaging Lt…ATEC logoATECAlphatec Holdings…SYK logoSYKStryker Corporati…ISRG logoISRGIntuitive Surgica…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$18.00$19.71$389.62$622.60
# AnalystsCovering analysts5185055
Dividend YieldAnnual dividend ÷ price+1.2%
Dividend StreakConsecutive years of raises34
Dividend / ShareAnnual DPS$3.36
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%+1.4%
Insufficient data to determine a leader in this category.
Key Takeaway

ISRG leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). SYK leads in 1 (Valuation Metrics). 1 tied.

Best OverallIntuitive Surgical, Inc. (ISRG)Leads 3 of 6 categories
Loading custom metrics...

NNOX vs ATEC vs SYK vs ISRG: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is NNOX or ATEC or SYK or ISRG a better buy right now?

For growth investors, Alphatec Holdings, Inc.

(ATEC) is the stronger pick with 25. 0% revenue growth year-over-year, versus 11. 2% for Stryker Corporation (SYK). Stryker Corporation (SYK) offers the better valuation at 34. 0x trailing P/E (19. 1x forward), making it the more compelling value choice. Analysts rate Nano-X Imaging Ltd. (NNOX) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — NNOX or ATEC or SYK or ISRG?

On trailing P/E, Stryker Corporation (SYK) is the cheapest at 34.

0x versus Intuitive Surgical, Inc. at 57. 2x. On forward P/E, Stryker Corporation is actually cheaper at 19. 1x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Stryker Corporation wins at 1. 28x versus Intuitive Surgical, Inc. 's 1. 99x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — NNOX or ATEC or SYK or ISRG?

Over the past 5 years, Intuitive Surgical, Inc.

(ISRG) delivered a total return of +61. 7%, compared to -93. 4% for Nano-X Imaging Ltd. (NNOX). Over 10 years, the gap is even starker: ISRG returned +549. 2% versus NNOX's -96. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — NNOX or ATEC or SYK or ISRG?

By beta (market sensitivity over 5 years), Stryker Corporation (SYK) is the lower-risk stock at 0.

52β versus Nano-X Imaging Ltd. 's 1. 75β — meaning NNOX is approximately 235% more volatile than SYK relative to the S&P 500. On balance sheet safety, Intuitive Surgical, Inc. (ISRG) carries a lower debt/equity ratio of 2% versus 17% for Alphatec Holdings, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — NNOX or ATEC or SYK or ISRG?

By revenue growth (latest reported year), Alphatec Holdings, Inc.

(ATEC) is pulling ahead at 25. 0% versus 11. 2% for Stryker Corporation (SYK). On earnings-per-share growth, the picture is similar: Intuitive Surgical, Inc. grew EPS 22. 6% year-over-year, compared to 8. 2% for Stryker Corporation. Over a 3-year CAGR, NNOX leads at 105. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — NNOX or ATEC or SYK or ISRG?

Intuitive Surgical, Inc.

(ISRG) is the more profitable company, earning 28. 4% net margin versus -474. 3% for Nano-X Imaging Ltd. — meaning it keeps 28. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ISRG leads at 29. 3% versus -502. 9% for NNOX. At the gross margin level — before operating expenses — ATEC leads at 69. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is NNOX or ATEC or SYK or ISRG more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Stryker Corporation (SYK) is the more undervalued stock at a PEG of 1. 28x versus Intuitive Surgical, Inc. 's 1. 99x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Stryker Corporation (SYK) trades at 19. 1x forward P/E versus 43. 3x for Intuitive Surgical, Inc. — 24. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NNOX: 940. 5% to $18. 00.

08

Which pays a better dividend — NNOX or ATEC or SYK or ISRG?

In this comparison, SYK (1.

2% yield) pays a dividend. NNOX, ATEC, ISRG do not pay a meaningful dividend and should not be held primarily for income.

09

Is NNOX or ATEC or SYK or ISRG better for a retirement portfolio?

For long-horizon retirement investors, Stryker Corporation (SYK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

52), 1. 2% yield, +179. 2% 10Y return). Nano-X Imaging Ltd. (NNOX) carries a higher beta of 1. 75 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SYK: +179. 2%, NNOX: -96. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between NNOX and ATEC and SYK and ISRG?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: NNOX is a small-cap quality compounder stock; ATEC is a small-cap high-growth stock; SYK is a mid-cap quality compounder stock; ISRG is a mid-cap high-growth stock. SYK pays a dividend while NNOX, ATEC, ISRG do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

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Stocks Like

NNOX

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 6%
Run This Screen
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ATEC

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 53%
Run This Screen
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SYK

Stable Dividend Mega-Cap

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 7%
Run This Screen
Stocks Like

ISRG

High-Growth Quality Leader

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 11%
  • Net Margin > 16%
Run This Screen
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Beat Both

Find stocks that outperform NNOX and ATEC and SYK and ISRG on the metrics below

Revenue Growth>
%
(NNOX: 13.7% · ATEC: -100.0%)

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