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Stock Comparison

NRIX vs IMVT vs KYMR vs RCUS

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
NRIX
Nurix Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.66B
5Y Perf.-30.4%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.53B
5Y Perf.-19.8%
KYMR
Kymera Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.91B
5Y Perf.+165.3%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.50B
5Y Perf.+4.2%

NRIX vs IMVT vs KYMR vs RCUS — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
NRIX logoNRIX
IMVT logoIMVT
KYMR logoKYMR
RCUS logoRCUS
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$1.66B$5.53B$6.91B$2.50B
Revenue (TTM)$84M$0.00$51M$236M
Net Income (TTM)$-264M$-464M$-315M$-369M
Gross Margin-87.4%33.2%90.7%
Operating Margin-340.2%-7.0%-168.6%
Total Debt$56M$98K$82M$99M
Cash & Equiv.$247M$714M$357M$222M

NRIX vs IMVT vs KYMR vs RCUSLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

NRIX
IMVT
KYMR
RCUS
StockAug 20May 26Return
Nurix Therapeutics,… (NRIX)10069.6-30.4%
Immunovant, Inc. (IMVT)10080.2-19.8%
Kymera Therapeutics… (KYMR)100265.3+165.3%
Arcus Biosciences, … (RCUS)100104.2+4.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: NRIX vs IMVT vs KYMR vs RCUS

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: KYMR leads in 2 of 6 categories, making it the strongest pick for capital preservation and lower volatility and operational efficiency and capital deployment. Nurix Therapeutics, Inc. is the stronger pick specifically for growth and revenue expansion. IMVT and RCUS also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
NRIX
Nurix Therapeutics, Inc.
The Growth Play

NRIX is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 54.0%, EPS growth -5.9%, 3Y rev CAGR 29.5%
  • 54.0% revenue growth vs IMVT's -21.3%
Best for: growth exposure
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT is the clearest fit if your priority is long-term compounding and sleep-well-at-night.

  • 173.6% 10Y total return vs KYMR's 154.4%
  • Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
  • 3.2% margin vs KYMR's -6.1%
Best for: long-term compounding and sleep-well-at-night
KYMR
Kymera Therapeutics, Inc.
The Income Pick

KYMR carries the broadest edge in this set and is the clearest fit for income & stability and defensive.

  • beta 1.15
  • Beta 1.15, current ratio 10.47x
  • Beta 1.15 vs RCUS's 1.95, lower leverage
  • -22.3% ROA vs IMVT's -44.1%
Best for: income & stability and defensive
RCUS
Arcus Biosciences, Inc.
The Momentum Pick

RCUS is the clearest fit if your priority is momentum.

  • +209.6% vs NRIX's +75.1%
Best for: momentum
See the full category breakdown
CategoryWinnerWhy
GrowthNRIX logoNRIX54.0% revenue growth vs IMVT's -21.3%
Quality / MarginsIMVT logoIMVT3.2% margin vs KYMR's -6.1%
Stability / SafetyKYMR logoKYMRBeta 1.15 vs RCUS's 1.95, lower leverage
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)RCUS logoRCUS+209.6% vs NRIX's +75.1%
Efficiency (ROA)KYMR logoKYMR-22.3% ROA vs IMVT's -44.1%

NRIX vs IMVT vs KYMR vs RCUS — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

NRIXNurix Therapeutics, Inc.
FY 2025
Collaboration Revenue
64.3%$54M
License Revenue
35.7%$30M
IMVTImmunovant, Inc.

Segment breakdown not available.

KYMRKymera Therapeutics, Inc.

Segment breakdown not available.

RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M

NRIX vs IMVT vs KYMR vs RCUS — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLKYMRLAGGINGIMVT

Income & Cash Flow (Last 12 Months)

RCUS leads this category, winning 4 of 6 comparable metrics.

RCUS and IMVT operate at a comparable scale, with $236M and $0 in trailing revenue. Profitability is closely matched — net margins range from -156.4% (RCUS) to -6.1% (KYMR). On growth, KYMR holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricNRIX logoNRIXNurix Therapeutic…IMVT logoIMVTImmunovant, Inc.KYMR logoKYMRKymera Therapeuti…RCUS logoRCUSArcus Biosciences…
RevenueTrailing 12 months$84M$0$51M$236M
EBITDAEarnings before interest/tax-$267M-$487M-$352M-$391M
Net IncomeAfter-tax profit-$264M-$464M-$315M-$369M
Free Cash FlowCash after capex-$263M-$423M-$244M-$489M
Gross MarginGross profit ÷ Revenue-87.4%+33.2%+90.7%
Operating MarginEBIT ÷ Revenue-3.4%-7.0%-168.6%
Net MarginNet income ÷ Revenue-3.1%-6.1%-156.4%
FCF MarginFCF ÷ Revenue-3.1%-4.7%-2.1%
Rev. Growth (YoY)Latest quarter vs prior year+2.2%+55.5%-39.3%
EPS Growth (YoY)Latest quarter vs prior year-9.3%+19.7%+13.4%+10.5%
RCUS leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

Evenly matched — NRIX and KYMR and RCUS each lead in 1 of 3 comparable metrics.
MetricNRIX logoNRIXNurix Therapeutic…IMVT logoIMVTImmunovant, Inc.KYMR logoKYMRKymera Therapeuti…RCUS logoRCUSArcus Biosciences…
Market CapShares × price$1.7B$5.5B$6.9B$2.5B
Enterprise ValueMkt cap + debt − cash$1.5B$4.8B$6.6B$2.4B
Trailing P/EPrice ÷ TTM EPS-5.34x-9.97x-22.93x-7.54x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue19.74x176.26x10.11x
Price / BookPrice ÷ Book value/share2.62x5.83x4.52x4.22x
Price / FCFMarket cap ÷ FCF
Evenly matched — NRIX and KYMR and RCUS each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

KYMR leads this category, winning 5 of 9 comparable metrics.

KYMR delivers a -25.0% return on equity — every $100 of shareholder capital generates $-25 in annual profit, vs $-69 for RCUS. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to RCUS's 0.16x. On the Piotroski fundamental quality scale (0–9), NRIX scores 4/9 vs RCUS's 0/9, reflecting mixed financial health.

MetricNRIX logoNRIXNurix Therapeutic…IMVT logoIMVTImmunovant, Inc.KYMR logoKYMRKymera Therapeuti…RCUS logoRCUSArcus Biosciences…
ROE (TTM)Return on equity-49.1%-47.1%-25.0%-69.0%
ROA (TTM)Return on assets-38.4%-44.1%-22.3%-35.3%
ROICReturn on invested capital-54.0%-24.9%-64.1%
ROCEReturn on capital employed-48.6%-66.1%-27.2%-42.1%
Piotroski ScoreFundamental quality 0–94240
Debt / EquityFinancial leverage0.10x0.00x0.05x0.16x
Net DebtTotal debt minus cash-$191M-$714M-$275M-$123M
Cash & Equiv.Liquid assets$247M$714M$357M$222M
Total DebtShort + long-term debt$56M$98,000$82M$99M
Interest CoverageEBIT ÷ Interest expense-2119.53x-13.38x
KYMR leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

KYMR leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in KYMR five years ago would be worth $19,212 today (with dividends reinvested), compared to $6,043 for NRIX. Over the past 12 months, RCUS leads with a +209.6% total return vs NRIX's +75.1%. The 3-year compound annual growth rate (CAGR) favors KYMR at 45.0% vs RCUS's 7.7% — a key indicator of consistent wealth creation.

MetricNRIX logoNRIXNurix Therapeutic…IMVT logoIMVTImmunovant, Inc.KYMR logoKYMRKymera Therapeuti…RCUS logoRCUSArcus Biosciences…
YTD ReturnYear-to-date-9.9%+5.1%+16.3%+6.5%
1-Year ReturnPast 12 months+75.1%+96.1%+190.7%+209.6%
3-Year ReturnCumulative with dividends+76.6%+40.9%+205.1%+24.9%
5-Year ReturnCumulative with dividends-39.6%+62.4%+92.1%-18.6%
10-Year ReturnCumulative with dividends-14.4%+173.6%+154.4%+45.9%
CAGR (3Y)Annualised 3-year return+20.9%+12.1%+45.0%+7.7%
KYMR leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — IMVT and KYMR each lead in 1 of 2 comparable metrics.

KYMR is the less volatile stock with a 1.15 beta — it tends to amplify market swings less than RCUS's 1.95 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs NRIX's 72.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricNRIX logoNRIXNurix Therapeutic…IMVT logoIMVTImmunovant, Inc.KYMR logoKYMRKymera Therapeuti…RCUS logoRCUSArcus Biosciences…
Beta (5Y)Sensitivity to S&P 5001.59x1.37x1.15x1.95x
52-Week HighHighest price in past year$22.50$30.09$103.00$28.72
52-Week LowLowest price in past year$8.20$13.36$28.06$7.06
% of 52W HighCurrent price vs 52-week peak+72.4%+90.5%+82.2%+86.3%
RSI (14)Momentum oscillator 0–10055.260.254.160.5
Avg Volume (50D)Average daily shares traded1.1M1.4M602K1.2M
Evenly matched — IMVT and KYMR each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: NRIX as "Buy", IMVT as "Buy", KYMR as "Buy", RCUS as "Buy". Consensus price targets imply 95.5% upside for NRIX (target: $32) vs 21.0% for RCUS (target: $30).

MetricNRIX logoNRIXNurix Therapeutic…IMVT logoIMVTImmunovant, Inc.KYMR logoKYMRKymera Therapeuti…RCUS logoRCUSArcus Biosciences…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$31.83$45.50$117.06$30.00
# AnalystsCovering analysts17232618
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

KYMR leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). RCUS leads in 1 (Income & Cash Flow). 2 tied.

Best OverallKymera Therapeutics, Inc. (KYMR)Leads 2 of 6 categories
Loading custom metrics...

NRIX vs IMVT vs KYMR vs RCUS: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is NRIX or IMVT or KYMR or RCUS a better buy right now?

For growth investors, Nurix Therapeutics, Inc.

(NRIX) is the stronger pick with 54. 0% revenue growth year-over-year, versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). Analysts rate Nurix Therapeutics, Inc. (NRIX) a "Buy" — based on 17 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — NRIX or IMVT or KYMR or RCUS?

Over the past 5 years, Kymera Therapeutics, Inc.

(KYMR) delivered a total return of +92. 1%, compared to -39. 6% for Nurix Therapeutics, Inc. (NRIX). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus NRIX's -14. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — NRIX or IMVT or KYMR or RCUS?

By beta (market sensitivity over 5 years), Kymera Therapeutics, Inc.

(KYMR) is the lower-risk stock at 1. 15β versus Arcus Biosciences, Inc. 's 1. 95β — meaning RCUS is approximately 70% more volatile than KYMR relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 16% for Arcus Biosciences, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — NRIX or IMVT or KYMR or RCUS?

By revenue growth (latest reported year), Nurix Therapeutics, Inc.

(NRIX) is pulling ahead at 54. 0% versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). On earnings-per-share growth, the picture is similar: Arcus Biosciences, Inc. grew EPS -4. 8% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — NRIX or IMVT or KYMR or RCUS?

Immunovant, Inc.

(IMVT) is the more profitable company, earning 0. 0% net margin versus -794. 4% for Kymera Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -891. 3% for KYMR. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — NRIX or IMVT or KYMR or RCUS?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is NRIX or IMVT or KYMR or RCUS better for a retirement portfolio?

For long-horizon retirement investors, Kymera Therapeutics, Inc.

(KYMR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 15), +154. 4% 10Y return). Arcus Biosciences, Inc. (RCUS) carries a higher beta of 1. 95 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KYMR: +154. 4%, RCUS: +45. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between NRIX and IMVT and KYMR and RCUS?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: NRIX is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; KYMR is a small-cap quality compounder stock; RCUS is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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KYMR

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  • Market Cap > $100B
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RCUS

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