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NVCR vs NKTR vs RCUS vs IMVT
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
NVCR vs NKTR vs RCUS vs IMVT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Medical - Instruments & Supplies | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $1.88B | $1.67B | $2.62B | $5.83B |
| Revenue (TTM) | $674M | $63M | $236M | $0.00 |
| Net Income (TTM) | $-173M | $-121M | $-369M | $-464M |
| Gross Margin | 75.2% | 86.9% | 90.7% | — |
| Operating Margin | -27.2% | -156.5% | -168.6% | — |
| Total Debt | $290M | $86M | $99M | $98K |
| Cash & Equiv. | $103M | $15M | $222M | $714M |
NVCR vs NKTR vs RCUS vs IMVT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| NovoCure Limited (NVCR) | 100 | 24.5 | -75.5% |
| Nektar Therapeutics (NKTR) | 100 | 26.1 | -73.9% |
| Arcus Biosciences, … (RCUS) | 100 | 82.9 | -17.1% |
| Immunovant, Inc. (IMVT) | 100 | 111.7 | +11.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: NVCR vs NKTR vs RCUS vs IMVT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
NVCR carries the broadest edge in this set and is the clearest fit for growth exposure.
- Rev growth 8.3%, EPS growth 21.8%, 3Y rev CAGR 6.8%
- 8.3% revenue growth vs NKTR's -43.9%
- -16.5% ROA vs NKTR's -45.2%, ROIC -16.4% vs -75.2%
NKTR is the clearest fit if your priority is momentum.
- +7.8% vs NVCR's +1.0%
RCUS lags the leaders in this set but could rank higher in a more targeted comparison.
IMVT is the #2 pick in this set and the best alternative if income & stability and long-term compounding is your priority.
- beta 1.37
- 188.1% 10Y total return vs RCUS's 52.9%
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- Beta 1.37, current ratio 11.16x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.3% revenue growth vs NKTR's -43.9% | |
| Quality / Margins | 3.2% margin vs NKTR's -192.9% | |
| Stability / Safety | Beta 1.37 vs NVCR's 2.20, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +7.8% vs NVCR's +1.0% | |
| Efficiency (ROA) | -16.5% ROA vs NKTR's -45.2%, ROIC -16.4% vs -75.2% |
NVCR vs NKTR vs RCUS vs IMVT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
NVCR vs NKTR vs RCUS vs IMVT — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
NVCR leads in 2 of 6 categories
NKTR leads 1 • IMVT leads 1 • RCUS leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
NVCR leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVCR and IMVT operate at a comparable scale, with $674M and $0 in trailing revenue. NVCR is the more profitable business, keeping -25.7% of every revenue dollar as net income compared to NKTR's -192.9%. On growth, NVCR holds the edge at +12.3% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $674M | $63M | $236M | $0 |
| EBITDAEarnings before interest/tax | -$165M | -$97M | -$391M | -$487M |
| Net IncomeAfter-tax profit | -$173M | -$121M | -$369M | -$464M |
| Free Cash FlowCash after capex | -$48M | -$190M | -$489M | -$423M |
| Gross MarginGross profit ÷ Revenue | +75.2% | +86.9% | +90.7% | — |
| Operating MarginEBIT ÷ Revenue | -27.2% | -156.5% | -168.6% | — |
| Net MarginNet income ÷ Revenue | -25.7% | -192.9% | -156.4% | — |
| FCF MarginFCF ÷ Revenue | -7.1% | -3.0% | -2.1% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | +12.3% | -51.1% | -39.3% | — |
| EPS Growth (YoY)Latest quarter vs prior year | -100.0% | +29.7% | +10.5% | +19.7% |
Valuation Metrics
NVCR leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $1.9B | $1.7B | $2.6B | $5.8B |
| Enterprise ValueMkt cap + debt − cash | $2.1B | $1.7B | $2.5B | $5.1B |
| Trailing P/EPrice ÷ TTM EPS | -13.52x | -8.75x | -7.90x | -10.50x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 2.86x | 30.28x | 10.60x | — |
| Price / BookPrice ÷ Book value/share | 5.40x | 15.98x | 4.43x | 6.14x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
Evenly matched — NVCR and IMVT each lead in 4 of 9 comparable metrics.
Profitability & Efficiency
IMVT delivers a -47.1% return on equity — every $100 of shareholder capital generates $-47 in annual profit, vs $-4 for NKTR. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 0.95x. On the Piotroski fundamental quality scale (0–9), NVCR scores 5/9 vs RCUS's 0/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -50.8% | -3.6% | -69.0% | -47.1% |
| ROA (TTM)Return on assets | -16.5% | -45.2% | -35.3% | -44.1% |
| ROICReturn on invested capital | -16.4% | -75.2% | -64.1% | — |
| ROCEReturn on capital employed | -28.9% | -59.7% | -42.1% | -66.1% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 2 | 0 | 2 |
| Debt / EquityFinancial leverage | 0.85x | 0.95x | 0.16x | 0.00x |
| Net DebtTotal debt minus cash | $187M | $71M | -$123M | -$714M |
| Cash & Equiv.Liquid assets | $103M | $15M | $222M | $714M |
| Total DebtShort + long-term debt | $290M | $86M | $99M | $98,000 |
| Interest CoverageEBIT ÷ Interest expense | -96.80x | -3.30x | -13.38x | — |
Total Returns (Dividends Reinvested)
NKTR leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $17,386 today (with dividends reinvested), compared to $852 for NVCR. Over the past 12 months, NKTR leads with a +783.6% total return vs NVCR's +1.0%. The 3-year compound annual growth rate (CAGR) favors NKTR at 94.6% vs NVCR's -38.1% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +25.7% | +96.0% | +11.6% | +10.7% |
| 1-Year ReturnPast 12 months | +1.0% | +783.6% | +220.2% | +107.2% |
| 3-Year ReturnCumulative with dividends | -76.2% | +636.7% | +31.0% | +48.4% |
| 5-Year ReturnCumulative with dividends | -91.5% | -69.4% | -13.7% | +73.9% |
| 10-Year ReturnCumulative with dividends | +31.0% | -57.6% | +52.9% | +188.1% |
| CAGR (3Y)Annualised 3-year return | -38.1% | +94.6% | +9.4% | +14.1% |
Risk & Volatility
IMVT leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
IMVT is the less volatile stock with a 1.37 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 95.3% from its 52-week high vs NKTR's 78.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.20x | 1.85x | 1.95x | 1.37x |
| 52-Week HighHighest price in past year | $20.06 | $109.00 | $28.72 | $30.09 |
| 52-Week LowLowest price in past year | $9.82 | $7.99 | $7.06 | $13.36 |
| % of 52W HighCurrent price vs 52-week peak | +82.2% | +78.1% | +90.5% | +95.3% |
| RSI (14)Momentum oscillator 0–100 | 67.5 | 52.0 | 60.9 | 55.7 |
| Avg Volume (50D)Average daily shares traded | 1.6M | 995K | 1.2M | 1.4M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: NVCR as "Buy", NKTR as "Buy", RCUS as "Buy", IMVT as "Buy". Consensus price targets imply 103.1% upside for NVCR (target: $34) vs 15.4% for RCUS (target: $30).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $33.50 | $132.83 | $30.00 | $45.50 |
| # AnalystsCovering analysts | 15 | 33 | 18 | 23 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
NVCR leads in 2 of 6 categories (Income & Cash Flow, Valuation Metrics). NKTR leads in 1 (Total Returns). 1 tied.
NVCR vs NKTR vs RCUS vs IMVT: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is NVCR or NKTR or RCUS or IMVT a better buy right now?
For growth investors, NovoCure Limited (NVCR) is the stronger pick with 8.
3% revenue growth year-over-year, versus -43. 9% for Nektar Therapeutics (NKTR). Analysts rate NovoCure Limited (NVCR) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — NVCR or NKTR or RCUS or IMVT?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +73. 9%, compared to -91. 5% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: IMVT returned +188. 1% versus NKTR's -57. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — NVCR or NKTR or RCUS or IMVT?
By beta (market sensitivity over 5 years), Immunovant, Inc.
(IMVT) is the lower-risk stock at 1. 37β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 60% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 95% for Nektar Therapeutics — giving it more financial flexibility in a downturn.
04Which is growing faster — NVCR or NKTR or RCUS or IMVT?
By revenue growth (latest reported year), NovoCure Limited (NVCR) is pulling ahead at 8.
3% versus -43. 9% for Nektar Therapeutics (NKTR). On earnings-per-share growth, the picture is similar: NovoCure Limited grew EPS 21. 8% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — NVCR or NKTR or RCUS or IMVT?
Immunovant, Inc.
(IMVT) is the more profitable company, earning 0. 0% net margin versus -297. 1% for Nektar Therapeutics — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -253. 7% for NKTR. At the gross margin level — before operating expenses — RCUS leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — NVCR or NKTR or RCUS or IMVT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is NVCR or NKTR or RCUS or IMVT better for a retirement portfolio?
For long-horizon retirement investors, Immunovant, Inc.
(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+188. 1% 10Y return). NovoCure Limited (NVCR) carries a higher beta of 2. 20 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +188. 1%, NVCR: +31. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between NVCR and NKTR and RCUS and IMVT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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