Medical - Instruments & Supplies
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PDEX vs NVCR vs HOLX vs SYK
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Instruments & Supplies
Medical - Instruments & Supplies
Medical - Devices
PDEX vs NVCR vs HOLX vs SYK — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Medical - Instruments & Supplies | Medical - Instruments & Supplies | Medical - Instruments & Supplies | Medical - Devices |
| Market Cap | $184M | $1.92B | $16.97B | $112.69B |
| Revenue (TTM) | $75M | $674M | $4.13B | $25.12B |
| Net Income (TTM) | $12M | $-173M | $544M | $3.25B |
| Gross Margin | 27.8% | 75.2% | 52.8% | 63.5% |
| Operating Margin | 14.5% | -27.2% | 17.5% | 22.4% |
| Forward P/E | 24.1x | — | 17.2x | 19.6x |
| Total Debt | $17M | $290M | $2.63B | $14.86B |
| Cash & Equiv. | $419K | $103M | $1.96B | $4.01B |
PDEX vs NVCR vs HOLX vs SYK — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Pro-Dex, Inc. (PDEX) | 100 | 291.5 | +191.5% |
| NovoCure Limited (NVCR) | 100 | 25.0 | -75.0% |
| Hologic, Inc. (HOLX) | 100 | 142.6 | +42.6% |
| Stryker Corporation (SYK) | 100 | 150.3 | +50.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: PDEX vs NVCR vs HOLX vs SYK
Each card shows where this stock fits in a portfolio — not just who wins on paper.
PDEX carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 1 yrs, beta 0.33
- Rev growth 23.7%, EPS growth 345.0%, 3Y rev CAGR 16.6%
- 14.2% 10Y total return vs SYK's 187.1%
- Lower volatility, beta 0.33, Low D/E 45.3%, current ratio 3.23x
NVCR lags the leaders in this set but could rank higher in a more targeted comparison.
HOLX is the #2 pick in this set and the best alternative if value and momentum is your priority.
- Better valuation composite
- +37.1% vs SYK's -22.5%
SYK is the clearest fit if your priority is valuation efficiency.
- PEG 1.32 vs PDEX's 1.97
- 1.1% yield; 34-year raise streak; the other 3 pay no meaningful dividend
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 23.7% revenue growth vs HOLX's 1.7% | |
| Value | Better valuation composite | |
| Quality / Margins | 16.1% margin vs NVCR's -25.7% | |
| Stability / Safety | Beta 0.33 vs NVCR's 2.20, lower leverage | |
| Dividends | 1.1% yield; 34-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +37.1% vs SYK's -22.5% | |
| Efficiency (ROA) | 18.3% ROA vs NVCR's -16.5%, ROIC 17.0% vs -16.4% |
PDEX vs NVCR vs HOLX vs SYK — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
PDEX vs NVCR vs HOLX vs SYK — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
PDEX leads in 2 of 6 categories
SYK leads 1 • NVCR leads 0 • HOLX leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — PDEX and SYK each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
SYK is the larger business by revenue, generating $25.1B annually — 336.5x PDEX's $75M. PDEX is the more profitable business, keeping 16.1% of every revenue dollar as net income compared to NVCR's -25.7%. On growth, PDEX holds the edge at +14.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $75M | $674M | $4.1B | $25.1B |
| EBITDAEarnings before interest/tax | $13M | -$165M | $974M | $6.3B |
| Net IncomeAfter-tax profit | $12M | -$173M | $544M | $3.2B |
| Free Cash FlowCash after capex | $7M | -$48M | $1000M | $4.3B |
| Gross MarginGross profit ÷ Revenue | +27.8% | +75.2% | +52.8% | +63.5% |
| Operating MarginEBIT ÷ Revenue | +14.5% | -27.2% | +17.5% | +22.4% |
| Net MarginNet income ÷ Revenue | +16.1% | -25.7% | +13.2% | +12.9% |
| FCF MarginFCF ÷ Revenue | +9.5% | -7.1% | +24.2% | +17.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | +14.6% | +12.3% | +2.5% | +11.4% |
| EPS Growth (YoY)Latest quarter vs prior year | +22.4% | -100.0% | -9.2% | +56.0% |
Valuation Metrics
Evenly matched — PDEX and HOLX each lead in 3 of 7 comparable metrics.
Valuation Metrics
At 21.5x trailing earnings, PDEX trades at a 39% valuation discount to SYK's 35.0x P/E. Adjusting for growth (PEG ratio), PDEX offers better value at 1.76x vs SYK's 2.36x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $184M | $1.9B | $17.0B | $112.7B |
| Enterprise ValueMkt cap + debt − cash | $200M | $2.1B | $17.6B | $123.5B |
| Trailing P/EPrice ÷ TTM EPS | 21.51x | -13.80x | 30.53x | 35.03x |
| Forward P/EPrice ÷ next-FY EPS est. | 24.13x | — | 17.21x | 19.62x |
| PEG RatioP/E ÷ EPS growth rate | 1.76x | — | — | 2.36x |
| EV / EBITDAEnterprise value multiple | 16.79x | — | 17.39x | 20.31x |
| Price / SalesMarket cap ÷ Revenue | 2.76x | 2.92x | 4.14x | 4.49x |
| Price / BookPrice ÷ Book value/share | 5.27x | 5.51x | 3.43x | 5.02x |
| Price / FCFMarket cap ÷ FCF | — | — | 18.44x | 26.31x |
Profitability & Efficiency
PDEX leads this category, winning 8 of 9 comparable metrics.
Profitability & Efficiency
PDEX delivers a 29.1% return on equity — every $100 of shareholder capital generates $29 in annual profit, vs $-51 for NVCR. PDEX carries lower financial leverage with a 0.45x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), HOLX scores 7/9 vs NVCR's 5/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | +29.1% | -50.8% | +11.0% | +15.0% |
| ROA (TTM)Return on assets | +18.3% | -16.5% | +6.1% | +6.9% |
| ROICReturn on invested capital | +17.0% | -16.4% | +9.4% | +11.4% |
| ROCEReturn on capital employed | +24.8% | -28.9% | +8.8% | +13.0% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 5 | 7 | 6 |
| Debt / EquityFinancial leverage | 0.45x | 0.85x | 0.52x | 0.66x |
| Net DebtTotal debt minus cash | $16M | $187M | $667M | $10.8B |
| Cash & Equiv.Liquid assets | $419,000 | $103M | $2.0B | $4.0B |
| Total DebtShort + long-term debt | $17M | $290M | $2.6B | $14.9B |
| Interest CoverageEBIT ÷ Interest expense | 32.18x | -96.80x | 8.00x | 6.72x |
Total Returns (Dividends Reinvested)
PDEX leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in PDEX five years ago would be worth $16,706 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, HOLX leads with a +37.1% total return vs SYK's -22.5%. The 3-year compound annual growth rate (CAGR) favors PDEX at 54.0% vs NVCR's -37.6% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +52.2% | +28.3% | +1.9% | -15.2% |
| 1-Year ReturnPast 12 months | +34.4% | +1.1% | +37.1% | -22.5% |
| 3-Year ReturnCumulative with dividends | +265.5% | -75.7% | -8.5% | +5.5% |
| 5-Year ReturnCumulative with dividends | +67.1% | -91.3% | +15.8% | +21.5% |
| 10-Year ReturnCumulative with dividends | +1423.1% | +30.3% | +124.3% | +187.1% |
| CAGR (3Y)Annualised 3-year return | +54.0% | -37.6% | -2.9% | +1.8% |
Risk & Volatility
Evenly matched — PDEX and HOLX each lead in 1 of 2 comparable metrics.
Risk & Volatility
PDEX is the less volatile stock with a 0.33 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs SYK's 72.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.33x | 2.20x | 0.41x | 0.55x |
| 52-Week HighHighest price in past year | $59.22 | $20.06 | $76.04 | $404.87 |
| 52-Week LowLowest price in past year | $23.47 | $9.82 | $52.81 | $289.91 |
| % of 52W HighCurrent price vs 52-week peak | +97.0% | +83.9% | +100.0% | +72.7% |
| RSI (14)Momentum oscillator 0–100 | 69.2 | 69.8 | 69.1 | 24.3 |
| Avg Volume (50D)Average daily shares traded | 26K | 1.5M | 10.0M | 2.1M |
Analyst Outlook
SYK leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: PDEX as "Buy", NVCR as "Buy", HOLX as "Hold", SYK as "Buy". Consensus price targets imply 99.0% upside for NVCR (target: $34) vs 3.9% for HOLX (target: $79). SYK is the only dividend payer here at 1.14% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Hold | Buy |
| Price TargetConsensus 12-month target | — | $33.50 | $79.00 | $403.69 |
| # AnalystsCovering analysts | 1 | 15 | 42 | 50 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +1.1% |
| Dividend StreakConsecutive years of raises | 1 | — | — | 34 |
| Dividend / ShareAnnual DPS | — | — | — | $3.36 |
| Buyback YieldShare repurchases ÷ mkt cap | +1.9% | 0.0% | +4.4% | 0.0% |
PDEX leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). SYK leads in 1 (Analyst Outlook). 3 tied.
PDEX vs NVCR vs HOLX vs SYK: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is PDEX or NVCR or HOLX or SYK a better buy right now?
For growth investors, Pro-Dex, Inc.
(PDEX) is the stronger pick with 23. 7% revenue growth year-over-year, versus 1. 7% for Hologic, Inc. (HOLX). Pro-Dex, Inc. (PDEX) offers the better valuation at 21. 5x trailing P/E (24. 1x forward), making it the more compelling value choice. Analysts rate Pro-Dex, Inc. (PDEX) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — PDEX or NVCR or HOLX or SYK?
On trailing P/E, Pro-Dex, Inc.
(PDEX) is the cheapest at 21. 5x versus Stryker Corporation at 35. 0x. On forward P/E, Hologic, Inc. is actually cheaper at 17. 2x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Stryker Corporation wins at 1. 32x versus Pro-Dex, Inc. 's 1. 97x — a reasonable growth-adjusted valuation.
03Which is the better long-term investment — PDEX or NVCR or HOLX or SYK?
Over the past 5 years, Pro-Dex, Inc.
(PDEX) delivered a total return of +67. 1%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: PDEX returned +1423% versus NVCR's +30. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — PDEX or NVCR or HOLX or SYK?
By beta (market sensitivity over 5 years), Pro-Dex, Inc.
(PDEX) is the lower-risk stock at 0. 33β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 578% more volatile than PDEX relative to the S&P 500. On balance sheet safety, Pro-Dex, Inc. (PDEX) carries a lower debt/equity ratio of 45% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.
05Which is growing faster — PDEX or NVCR or HOLX or SYK?
By revenue growth (latest reported year), Pro-Dex, Inc.
(PDEX) is pulling ahead at 23. 7% versus 1. 7% for Hologic, Inc. (HOLX). On earnings-per-share growth, the picture is similar: Pro-Dex, Inc. grew EPS 345. 0% year-over-year, compared to -25. 0% for Hologic, Inc.. Over a 3-year CAGR, PDEX leads at 16. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — PDEX or NVCR or HOLX or SYK?
Hologic, Inc.
(HOLX) is the more profitable company, earning 13. 8% net margin versus -20. 8% for NovoCure Limited — meaning it keeps 13. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: SYK leads at 19. 5% versus -23. 5% for NVCR. At the gross margin level — before operating expenses — NVCR leads at 74. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is PDEX or NVCR or HOLX or SYK more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Stryker Corporation (SYK) is the more undervalued stock at a PEG of 1. 32x versus Pro-Dex, Inc. 's 1. 97x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Hologic, Inc. (HOLX) trades at 17. 2x forward P/E versus 24. 1x for Pro-Dex, Inc. — 6. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NVCR: 99. 0% to $33. 50.
08Which pays a better dividend — PDEX or NVCR or HOLX or SYK?
In this comparison, SYK (1.
1% yield) pays a dividend. PDEX, NVCR, HOLX do not pay a meaningful dividend and should not be held primarily for income.
09Is PDEX or NVCR or HOLX or SYK better for a retirement portfolio?
For long-horizon retirement investors, Pro-Dex, Inc.
(PDEX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 33), +1423% 10Y return). NovoCure Limited (NVCR) carries a higher beta of 2. 20 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (PDEX: +1423%, NVCR: +30. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between PDEX and NVCR and HOLX and SYK?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: PDEX is a small-cap high-growth stock; NVCR is a small-cap quality compounder stock; HOLX is a mid-cap quality compounder stock; SYK is a mid-cap quality compounder stock. SYK pays a dividend while PDEX, NVCR, HOLX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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