Biotechnology
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Side-by-side financial analysisStock Comparison
QTTB vs ARQT vs KO vs REGN vs ABBV
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Beverages - Non-Alcoholic
Biotechnology
Drug Manufacturers - General
QTTB vs ARQT vs KO vs REGN vs ABBV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Beverages - Non-Alcoholic | Biotechnology | Drug Manufacturers - General |
| Market Cap | $161M | $3.05B | $355.61B | $63.60B | $402.80B |
| Revenue (TTM) | $54M | $416M | $49.28B | $14.92B | $61.16B |
| Net Income (TTM) | $33M | $-2M | $13.70B | $4.42B | $4.23B |
| Gross Margin | 99.5% | 90.9% | 61.7% | 84.5% | 70.2% |
| Operating Margin | 39.8% | 0.8% | 29.3% | 24.3% | 26.7% |
| Forward P/E | 5.2x | 122.5x | 25.3x | 13.2x | 16.0x |
| Total Debt | $15M | $6M | $45.49B | $2.71B | $69.07B |
| Cash & Equiv. | $48M | $43M | $10.27B | $3.12B | $5.23B |
QTTB vs ARQT vs KO vs REGN vs ABBV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jun 20 | Jun 26 | Return |
|---|---|---|---|
| Q32 Bio Inc. (QTTB) | 100 | 4.6 | -95.4% |
| Arcutis Biotherapeu… (ARQT) | 100 | 80.6 | -19.4% |
| The Coca-Cola Compa… (KO) | 100 | 184.9 | +84.9% |
| Regeneron Pharmaceu… (REGN) | 100 | 98.2 | -1.8% |
| AbbVie Inc. (ABBV) | 100 | 232.0 | +132.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: QTTB vs ARQT vs KO vs REGN vs ABBV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
QTTB carries the broadest edge in this set and is the clearest fit for sleep-well-at-night.
- Lower volatility, beta 0.50, Low D/E 36.5%, current ratio 4.85x
- 156.7% revenue growth vs REGN's 1.0%
- 61.9% margin vs ARQT's -0.6%
- +6.4% vs KO's +17.2%
ARQT is the clearest fit if your priority is growth exposure.
- Rev growth 91.3%, EPS growth 88.8%, 3Y rev CAGR 367.3%
Among these 5 stocks, KO doesn't own a clear edge in any measured category.
REGN ranks third and is worth considering specifically for valuation efficiency.
- PEG 2.08 vs KO's 2.26
- Lower P/E (13.2x vs 16.0x)
ABBV is the #2 pick in this set and the best alternative if income & stability and long-term compounding is your priority.
- Dividend streak 43 yrs, beta 0.14, yield 2.9%
- 362.2% 10Y total return vs KO's 121.1%
- Beta 0.14, yield 2.9%, current ratio 0.67x
- Beta 0.14 vs ARQT's 1.45
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 156.7% revenue growth vs REGN's 1.0% | |
| Value | Lower P/E (13.2x vs 16.0x) | |
| Quality / Margins | 61.9% margin vs ARQT's -0.6% | |
| Stability / Safety | Beta 0.14 vs ARQT's 1.45 | |
| Dividends | 2.9% yield, 43-year raise streak, vs KO's 2.5%, (2 stocks pay no dividend) | |
| Momentum (1Y) | +6.4% vs KO's +17.2% | |
| Efficiency (ROA) | 53.3% ROA vs ARQT's -0.6% |
QTTB vs ARQT vs KO vs REGN vs ABBV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
QTTB vs ARQT vs KO vs REGN vs ABBV — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
QTTB leads in 1 of 6 categories
REGN leads 1 • KO leads 1 • ARQT leads 0 • ABBV leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
QTTB leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ABBV is the larger business by revenue, generating $61.2B annually — 1138.1x QTTB's $54M. QTTB is the more profitable business, keeping 61.9% of every revenue dollar as net income compared to ARQT's -0.6%. On growth, ARQT holds the edge at +60.1% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $54M | $416M | $49.3B | $14.9B | $61.2B |
| EBITDAEarnings before interest/tax | $22M | $6M | $15.5B | $4.2B | $24.5B |
| Net IncomeAfter-tax profit | $33M | -$2M | $13.7B | $4.4B | $4.2B |
| Free Cash FlowCash after capex | -$27M | $27M | $12.6B | $4.2B | $18.7B |
| Gross MarginGross profit ÷ Revenue | +99.5% | +90.9% | +61.7% | +84.5% | +70.2% |
| Operating MarginEBIT ÷ Revenue | +39.8% | +0.8% | +29.3% | +24.3% | +26.7% |
| Net MarginNet income ÷ Revenue | +61.9% | -0.6% | +27.8% | +29.6% | +6.9% |
| FCF MarginFCF ÷ Revenue | -51.0% | +6.5% | +25.5% | +27.9% | +30.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +60.1% | +12.1% | +19.0% | +10.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +40.0% | +55.0% | +18.2% | -7.2% | +57.4% |
Valuation Metrics
REGN leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 5.2x trailing earnings, QTTB trades at a 95% valuation discount to ABBV's 96.1x P/E. Adjusting for growth (PEG ratio), REGN offers better value at 2.33x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $161M | $3.0B | $355.6B | $63.6B | $402.8B |
| Enterprise ValueMkt cap + debt − cash | $129M | $3.0B | $390.8B | $63.2B | $466.6B |
| Trailing P/EPrice ÷ TTM EPS | 5.22x | -187.54x | 27.18x | 14.76x | 96.09x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 122.45x | 25.27x | 13.18x | 15.96x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 2.43x | 2.33x | — |
| EV / EBITDAEnterprise value multiple | 7.43x | — | 26.39x | 15.33x | 16.53x |
| Price / SalesMarket cap ÷ Revenue | 3.01x | 8.11x | 7.42x | 4.43x | 6.59x |
| Price / BookPrice ÷ Book value/share | 3.70x | 16.37x | 10.40x | 2.13x | — |
| Price / FCFMarket cap ÷ FCF | — | — | 67.15x | 15.59x | 22.61x |
Profitability & Efficiency
Evenly matched — QTTB and ARQT and REGN and ABBV each lead in 2 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-1 for ARQT. ARQT carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to KO's 1.33x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs ARQT's 4/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +2.3% | -1.4% | +41.1% | +14.3% | +62.1% |
| ROA (TTM)Return on assets | +53.3% | -0.6% | +13.1% | +11.1% | +3.1% |
| ROICReturn on invested capital | — | -5.2% | +15.8% | +8.9% | +23.9% |
| ROCEReturn on capital employed | +26.8% | -4.3% | +17.3% | +10.2% | +21.5% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 | 7 | 5 | 6 |
| Debt / EquityFinancial leverage | 0.37x | 0.03x | 1.33x | 0.09x | — |
| Net DebtTotal debt minus cash | -$33M | -$37M | $35.2B | -$412M | $63.8B |
| Cash & Equiv.Liquid assets | $48M | $43M | $10.3B | $3.1B | $5.2B |
| Total DebtShort + long-term debt | $15M | $6M | $45.5B | $2.7B | $69.1B |
| Interest CoverageEBIT ÷ Interest expense | 21.88x | 2.08x | 10.70x | 108.44x | 3.28x |
Total Returns (Dividends Reinvested)
Evenly matched — QTTB and ARQT and ABBV each lead in 2 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $22,367 today (with dividends reinvested), compared to $950 for QTTB. Over the past 12 months, QTTB leads with a +643.5% total return vs KO's +17.2%. The 3-year compound annual growth rate (CAGR) favors ARQT at 33.7% vs QTTB's -14.4% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +267.4% | -15.9% | +20.3% | -20.9% | +0.8% |
| 1-Year ReturnPast 12 months | +643.5% | +80.6% | +17.2% | +18.0% | +21.9% |
| 3-Year ReturnCumulative with dividends | -37.3% | +138.8% | +47.0% | -18.1% | +79.3% |
| 5-Year ReturnCumulative with dividends | -90.5% | -16.2% | +65.6% | +16.8% | +123.7% |
| 10-Year ReturnCumulative with dividends | -96.2% | +11.8% | +121.1% | +68.2% | +362.2% |
| CAGR (3Y)Annualised 3-year return | -14.4% | +33.7% | +13.7% | -6.4% | +21.5% |
Risk & Volatility
KO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than ARQT's 1.45 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs REGN's 74.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.50x | 1.45x | -0.20x | 0.51x | 0.14x |
| 52-Week HighHighest price in past year | $14.85 | $31.77 | $84.04 | $821.11 | $244.81 |
| 52-Week LowLowest price in past year | $1.35 | $12.72 | $65.35 | $503.25 | $181.73 |
| % of 52W HighCurrent price vs 52-week peak | +85.1% | +76.7% | +98.3% | +74.6% | +93.0% |
| RSI (14)Momentum oscillator 0–100 | 64.2 | 66.4 | 60.6 | 37.5 | 62.8 |
| Avg Volume (50D)Average daily shares traded | 827K | 1.5M | 12.7M | 868K | 4.6M |
Analyst Outlook
Evenly matched — KO and ABBV each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: QTTB as "Hold", ARQT as "Buy", KO as "Buy", REGN as "Buy", ABBV as "Buy". Consensus price targets imply 39.5% upside for ARQT (target: $34) vs 4.2% for KO (target: $86). For income investors, ABBV offers the higher dividend yield at 2.89% vs REGN's 0.56%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $13.50 | $34.00 | $86.13 | $836.00 | $256.92 |
| # AnalystsCovering analysts | 8 | 12 | 48 | 48 | 41 |
| Dividend YieldAnnual dividend ÷ price | — | — | +2.5% | +0.6% | +2.9% |
| Dividend StreakConsecutive years of raises | — | — | 56 | 1 | 43 |
| Dividend / ShareAnnual DPS | — | — | $2.04 | $3.41 | $6.57 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.2% | +6.2% | +0.2% |
QTTB leads in 1 of 6 categories (Income & Cash Flow). REGN leads in 1 (Valuation Metrics). 3 tied.
QTTB vs ARQT vs KO vs REGN vs ABBV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is QTTB or ARQT or KO or REGN or ABBV a better buy right now?
For growth investors, Arcutis Biotherapeutics, Inc.
(ARQT) is the stronger pick with 91. 3% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Q32 Bio Inc. (QTTB) offers the better valuation at 5. 2x trailing P/E, making it the more compelling value choice. Analysts rate Arcutis Biotherapeutics, Inc. (ARQT) a "Buy" — based on 12 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — QTTB or ARQT or KO or REGN or ABBV?
On trailing P/E, Q32 Bio Inc.
(QTTB) is the cheapest at 5. 2x versus AbbVie Inc. at 96. 1x. On forward P/E, Regeneron Pharmaceuticals, Inc. is actually cheaper at 13. 2x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Regeneron Pharmaceuticals, Inc. wins at 2. 08x versus The Coca-Cola Company's 2. 26x.
03Which is the better long-term investment — QTTB or ARQT or KO or REGN or ABBV?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +123. 7%, compared to -90. 5% for Q32 Bio Inc. (QTTB). Over 10 years, the gap is even starker: ABBV returned +362. 2% versus QTTB's -96. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — QTTB or ARQT or KO or REGN or ABBV?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
20β versus Arcutis Biotherapeutics, Inc. 's 1. 45β — meaning ARQT is approximately -823% more volatile than KO relative to the S&P 500. On balance sheet safety, Arcutis Biotherapeutics, Inc. (ARQT) carries a lower debt/equity ratio of 3% versus 133% for The Coca-Cola Company — giving it more financial flexibility in a downturn.
05Which is growing faster — QTTB or ARQT or KO or REGN or ABBV?
By revenue growth (latest reported year), Arcutis Biotherapeutics, Inc.
(ARQT) is pulling ahead at 91. 3% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: Q32 Bio Inc. grew EPS 136. 8% year-over-year, compared to -0. 8% for AbbVie Inc.. Over a 3-year CAGR, ARQT leads at 367. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — QTTB or ARQT or KO or REGN or ABBV?
Q32 Bio Inc.
(QTTB) is the more profitable company, earning 55. 5% net margin versus -4. 3% for Arcutis Biotherapeutics, Inc. — meaning it keeps 55. 5% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABBV leads at 32. 8% versus -3. 3% for ARQT. At the gross margin level — before operating expenses — QTTB leads at 99. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is QTTB or ARQT or KO or REGN or ABBV more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Regeneron Pharmaceuticals, Inc. (REGN) is the more undervalued stock at a PEG of 2. 08x versus The Coca-Cola Company's 2. 26x. Both stocks trade at elevated growth-adjusted valuations, so expected growth needs to materialise. On forward earnings alone, Regeneron Pharmaceuticals, Inc. (REGN) trades at 13. 2x forward P/E versus 122. 5x for Arcutis Biotherapeutics, Inc. — 109. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ARQT: 39. 5% to $34. 00.
08Which pays a better dividend — QTTB or ARQT or KO or REGN or ABBV?
In this comparison, ABBV (2.
9% yield), KO (2. 5% yield), REGN (0. 6% yield) pay a dividend. QTTB, ARQT do not pay a meaningful dividend and should not be held primarily for income.
09Is QTTB or ARQT or KO or REGN or ABBV better for a retirement portfolio?
For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
20), 2. 5% yield, +121. 1% 10Y return). Both have compounded well over 10 years (KO: +121. 1%, ARQT: +11. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between QTTB and ARQT and KO and REGN and ABBV?
These companies operate in different sectors (QTTB (Healthcare) and ARQT (Healthcare) and KO (Consumer Defensive) and REGN (Healthcare) and ABBV (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: QTTB is a small-cap deep-value stock; ARQT is a small-cap high-growth stock; KO is a large-cap quality compounder stock; REGN is a mid-cap deep-value stock; ABBV is a large-cap quality compounder stock. KO, REGN, ABBV pay a dividend while QTTB, ARQT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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