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RAPP vs NKTR vs RCUS vs IMVT
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
RAPP vs NKTR vs RCUS vs IMVT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $1.46B | $1.69B | $2.50B | $5.53B |
| Revenue (TTM) | $20M | $55M | $236M | $0.00 |
| Net Income (TTM) | $-107M | $-164M | $-369M | $-464M |
| Gross Margin | -1.3% | 99.6% | 90.7% | — |
| Operating Margin | -6.1% | -237.9% | -168.6% | — |
| Total Debt | $11M | $149M | $99M | $98K |
| Cash & Equiv. | $53M | $15M | $222M | $714M |
RAPP vs NKTR vs RCUS vs IMVT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jun 24 | May 26 | Return |
|---|---|---|---|
| Rapport Therapeutic… (RAPP) | 100 | 171.7 | +71.7% |
| Nektar Therapeutics (NKTR) | 100 | 448.2 | +348.2% |
| Arcus Biosciences, … (RCUS) | 100 | 162.8 | +62.8% |
| Immunovant, Inc. (IMVT) | 100 | 103.1 | +3.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: RAPP vs NKTR vs RCUS vs IMVT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
RAPP is the #2 pick in this set and the best alternative if efficiency is your priority.
- -23.4% ROA vs NKTR's -62.8%, ROIC -27.1% vs -57.2%
NKTR is the clearest fit if your priority is momentum.
- +8.2% vs IMVT's +96.1%
RCUS is the clearest fit if your priority is growth exposure.
- Rev growth -4.3%, EPS growth -4.8%, 3Y rev CAGR 30.2%
- -4.3% revenue growth vs NKTR's -43.9%
IMVT carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.
- beta 1.37
- 173.6% 10Y total return vs RAPP's 92.0%
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- Beta 1.37, current ratio 11.16x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | -4.3% revenue growth vs NKTR's -43.9% | |
| Quality / Margins | 3.2% margin vs RAPP's -5.4% | |
| Stability / Safety | Beta 1.37 vs RCUS's 1.95, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +8.2% vs IMVT's +96.1% | |
| Efficiency (ROA) | -23.4% ROA vs NKTR's -62.8%, ROIC -27.1% vs -57.2% |
RAPP vs NKTR vs RCUS vs IMVT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
RAPP vs NKTR vs RCUS vs IMVT — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
RAPP leads in 2 of 6 categories
RCUS leads 1 • NKTR leads 1 • IMVT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
RCUS leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
RCUS and IMVT operate at a comparable scale, with $236M and $0 in trailing revenue. Profitability is closely matched — net margins range from -156.4% (RCUS) to -5.4% (RAPP). On growth, NKTR holds the edge at -25.3% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $20M | $55M | $236M | $0 |
| EBITDAEarnings before interest/tax | -$121M | -$130M | -$391M | -$487M |
| Net IncomeAfter-tax profit | -$107M | -$164M | -$369M | -$464M |
| Free Cash FlowCash after capex | -$80M | -$209M | -$489M | -$423M |
| Gross MarginGross profit ÷ Revenue | -1.3% | +99.6% | +90.7% | — |
| Operating MarginEBIT ÷ Revenue | -6.1% | -2.4% | -168.6% | — |
| Net MarginNet income ÷ Revenue | -5.4% | -3.0% | -156.4% | — |
| FCF MarginFCF ÷ Revenue | -4.0% | -3.8% | -2.1% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -25.3% | -39.3% | — |
| EPS Growth (YoY)Latest quarter vs prior year | +38.2% | -4.5% | +10.5% | +19.7% |
Valuation Metrics
RAPP leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $1.5B | $1.7B | $2.5B | $5.5B |
| Enterprise ValueMkt cap + debt − cash | $1.4B | $1.8B | $2.4B | $4.8B |
| Trailing P/EPrice ÷ TTM EPS | -13.96x | -8.57x | -7.54x | -9.97x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 30.64x | 10.11x | — |
| Price / BookPrice ÷ Book value/share | 3.87x | 15.66x | 4.22x | 5.83x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
RAPP leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
RAPP delivers a -24.8% return on equity — every $100 of shareholder capital generates $-25 in annual profit, vs $-4 for NKTR. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 1.66x. On the Piotroski fundamental quality scale (0–9), RAPP scores 2/9 vs RCUS's 0/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -24.8% | -4.0% | -69.0% | -47.1% |
| ROA (TTM)Return on assets | -23.4% | -62.8% | -35.3% | -44.1% |
| ROICReturn on invested capital | -27.1% | -57.2% | -64.1% | — |
| ROCEReturn on capital employed | -31.3% | -55.7% | -42.1% | -66.1% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 2 | 0 | 2 |
| Debt / EquityFinancial leverage | 0.02x | 1.66x | 0.16x | 0.00x |
| Net DebtTotal debt minus cash | -$41M | $134M | -$123M | -$714M |
| Cash & Equiv.Liquid assets | $53M | $15M | $222M | $714M |
| Total DebtShort + long-term debt | $11M | $149M | $99M | $98,000 |
| Interest CoverageEBIT ÷ Interest expense | — | -4.74x | -13.38x | — |
Total Returns (Dividends Reinvested)
NKTR leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in RAPP five years ago would be worth $19,197 today (with dividends reinvested), compared to $2,765 for NKTR. Over the past 12 months, NKTR leads with a +818.2% total return vs IMVT's +96.1%. The 3-year compound annual growth rate (CAGR) favors NKTR at 93.3% vs RCUS's 7.7% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +42.0% | +92.0% | +6.5% | +5.1% |
| 1-Year ReturnPast 12 months | +290.7% | +818.2% | +209.6% | +96.1% |
| 3-Year ReturnCumulative with dividends | +92.0% | +621.8% | +24.9% | +40.9% |
| 5-Year ReturnCumulative with dividends | +92.0% | -72.3% | -18.6% | +62.4% |
| 10-Year ReturnCumulative with dividends | +92.0% | -59.1% | +45.9% | +173.6% |
| CAGR (3Y)Annualised 3-year return | +24.3% | +93.3% | +7.7% | +12.1% |
Risk & Volatility
Evenly matched — RAPP and IMVT each lead in 1 of 2 comparable metrics.
Risk & Volatility
IMVT is the less volatile stock with a 1.37 beta — it tends to amplify market swings less than RCUS's 1.95 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. RAPP currently trades 94.5% from its 52-week high vs NKTR's 76.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.55x | 1.85x | 1.95x | 1.37x |
| 52-Week HighHighest price in past year | $42.27 | $109.00 | $28.72 | $30.09 |
| 52-Week LowLowest price in past year | $7.73 | $7.99 | $7.06 | $13.36 |
| % of 52W HighCurrent price vs 52-week peak | +94.5% | +76.5% | +86.3% | +90.5% |
| RSI (14)Momentum oscillator 0–100 | 61.9 | 53.4 | 60.5 | 60.2 |
| Avg Volume (50D)Average daily shares traded | 335K | 991K | 1.2M | 1.4M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: RAPP as "Buy", NKTR as "Buy", RCUS as "Buy", IMVT as "Buy". Consensus price targets imply 67.2% upside for IMVT (target: $46) vs 21.0% for RCUS (target: $30).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $49.00 | $132.83 | $30.00 | $45.50 |
| # AnalystsCovering analysts | 5 | 33 | 18 | 23 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
RAPP leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). RCUS leads in 1 (Income & Cash Flow). 1 tied.
RAPP vs NKTR vs RCUS vs IMVT: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is RAPP or NKTR or RCUS or IMVT a better buy right now?
For growth investors, Arcus Biosciences, Inc.
(RCUS) is the stronger pick with -4. 3% revenue growth year-over-year, versus -43. 9% for Nektar Therapeutics (NKTR). Analysts rate Rapport Therapeutics, Inc. Common Stock (RAPP) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — RAPP or NKTR or RCUS or IMVT?
Over the past 5 years, Rapport Therapeutics, Inc.
Common Stock (RAPP) delivered a total return of +92. 0%, compared to -72. 3% for Nektar Therapeutics (NKTR). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus NKTR's -59. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — RAPP or NKTR or RCUS or IMVT?
By beta (market sensitivity over 5 years), Immunovant, Inc.
(IMVT) is the lower-risk stock at 1. 37β versus Arcus Biosciences, Inc. 's 1. 95β — meaning RCUS is approximately 42% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 166% for Nektar Therapeutics — giving it more financial flexibility in a downturn.
04Which is growing faster — RAPP or NKTR or RCUS or IMVT?
By revenue growth (latest reported year), Arcus Biosciences, Inc.
(RCUS) is pulling ahead at -4. 3% versus -43. 9% for Nektar Therapeutics (NKTR). On earnings-per-share growth, the picture is similar: Rapport Therapeutics, Inc. Common Stock grew EPS 24. 3% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — RAPP or NKTR or RCUS or IMVT?
Immunovant, Inc.
(IMVT) is the more profitable company, earning 0. 0% net margin versus -536. 4% for Rapport Therapeutics, Inc. Common Stock — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -611. 0% for RAPP. At the gross margin level — before operating expenses — NKTR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — RAPP or NKTR or RCUS or IMVT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is RAPP or NKTR or RCUS or IMVT better for a retirement portfolio?
For long-horizon retirement investors, Immunovant, Inc.
(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+173. 6% 10Y return). Arcus Biosciences, Inc. (RCUS) carries a higher beta of 1. 95 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +173. 6%, RCUS: +45. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between RAPP and NKTR and RCUS and IMVT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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