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Stock Comparison

REGN vs BIIB

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
REGN
Regeneron Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$72.97B
5Y Perf.+14.6%
BIIB
Biogen Inc.

Drug Manufacturers - General

HealthcareNASDAQ • US
Market Cap$27.92B
5Y Perf.-38.4%

REGN vs BIIB — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
REGN logoREGN
BIIB logoBIIB
IndustryBiotechnologyDrug Manufacturers - General
Market Cap$72.97B$27.92B
Revenue (TTM)$14.92B$9.86B
Net Income (TTM)$4.42B$1.37B
Gross Margin84.5%69.8%
Operating Margin24.3%15.6%
Forward P/E15.2x12.9x
Total Debt$2.71B$6.95B
Cash & Equiv.$3.12B$3.01B

REGN vs BIIBLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

REGN
BIIB
StockMay 20May 26Return
Regeneron Pharmaceu… (REGN)100114.6+14.6%
Biogen Inc. (BIIB)10061.6-38.4%

Price return only. Dividends and distributions are not included.

Quick Verdict: REGN vs BIIB

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: BIIB leads in 4 of 7 categories, making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. Regeneron Pharmaceuticals, Inc. is the stronger pick specifically for profitability and margin quality and dividend income and shareholder returns. As sector peers, any of these can serve as alternatives in the same allocation.
REGN
Regeneron Pharmaceuticals, Inc.
The Income Pick

REGN is the clearest fit if your priority is income & stability and growth exposure.

  • Dividend streak 1 yrs, beta 0.81, yield 0.5%
  • Rev growth 1.0%, EPS growth 8.2%, 3Y rev CAGR 5.6%
  • 87.1% 10Y total return vs BIIB's -28.5%
Best for: income & stability and growth exposure
BIIB
Biogen Inc.
The Defensive Pick

BIIB carries the broadest edge in this set and is the clearest fit for defensive.

  • Beta 0.64, current ratio 2.68x
  • 1.4% revenue growth vs REGN's 1.0%
  • Lower P/E (12.9x vs 15.2x)
Best for: defensive
See the full category breakdown
CategoryWinnerWhy
GrowthBIIB logoBIIB1.4% revenue growth vs REGN's 1.0%
ValueBIIB logoBIIBLower P/E (12.9x vs 15.2x)
Quality / MarginsREGN logoREGN29.6% margin vs BIIB's 13.9%
Stability / SafetyBIIB logoBIIBBeta 0.64 vs REGN's 0.81
DividendsREGN logoREGN0.5% yield; 1-year raise streak; the other pay no meaningful dividend
Momentum (1Y)BIIB logoBIIB+55.3% vs REGN's +17.0%
Efficiency (ROA)REGN logoREGN11.1% ROA vs BIIB's 4.7%, ROIC 8.9% vs 6.5%

REGN vs BIIB — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

REGNRegeneron Pharmaceuticals, Inc.
FY 2025
Collaboration Revenue
51.1%$7.3B
Product
44.0%$6.3B
Product and Service, Other
4.9%$703M
BIIBBiogen Inc.
FY 2025
MS Product Revenues
42.0%$4.0B
TYSABRI product
17.3%$1.7B
SPINRAZA
16.1%$1.5B
Fumarate
14.8%$1.4B
Interferon
9.8%$946M

REGN vs BIIB — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLREGNLAGGINGBIIB

Income & Cash Flow (Last 12 Months)

REGN leads this category, winning 5 of 6 comparable metrics.

REGN is the larger business by revenue, generating $14.9B annually — 1.5x BIIB's $9.9B. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to BIIB's 13.9%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricREGN logoREGNRegeneron Pharmac…BIIB logoBIIBBiogen Inc.
RevenueTrailing 12 months$14.9B$9.9B
EBITDAEarnings before interest/tax$4.2B$2.4B
Net IncomeAfter-tax profit$4.4B$1.4B
Free Cash FlowCash after capex$4.2B$2.6B
Gross MarginGross profit ÷ Revenue+84.5%+69.8%
Operating MarginEBIT ÷ Revenue+24.3%+15.6%
Net MarginNet income ÷ Revenue+29.6%+13.9%
FCF MarginFCF ÷ Revenue+27.9%+26.6%
Rev. Growth (YoY)Latest quarter vs prior year+19.0%+1.9%
EPS Growth (YoY)Latest quarter vs prior year-7.2%+31.1%
REGN leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

BIIB leads this category, winning 5 of 6 comparable metrics.

At 16.9x trailing earnings, REGN trades at a 21% valuation discount to BIIB's 21.4x P/E. On an enterprise value basis, BIIB's 11.3x EV/EBITDA is more attractive than REGN's 17.6x.

MetricREGN logoREGNRegeneron Pharmac…BIIB logoBIIBBiogen Inc.
Market CapShares × price$73.0B$27.9B
Enterprise ValueMkt cap + debt − cash$72.6B$31.9B
Trailing P/EPrice ÷ TTM EPS16.93x21.42x
Forward P/EPrice ÷ next-FY EPS est.15.20x12.89x
PEG RatioP/E ÷ EPS growth rate2.68x
EV / EBITDAEnterprise value multiple17.61x11.33x
Price / SalesMarket cap ÷ Revenue5.09x2.85x
Price / BookPrice ÷ Book value/share2.44x1.52x
Price / FCFMarket cap ÷ FCF17.88x13.62x
BIIB leads this category, winning 5 of 6 comparable metrics.

Profitability & Efficiency

REGN leads this category, winning 8 of 8 comparable metrics.

REGN delivers a 14.3% return on equity — every $100 of shareholder capital generates $14 in annual profit, vs $8 for BIIB. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to BIIB's 0.38x.

MetricREGN logoREGNRegeneron Pharmac…BIIB logoBIIBBiogen Inc.
ROE (TTM)Return on equity+14.3%+7.5%
ROA (TTM)Return on assets+11.1%+4.7%
ROICReturn on invested capital+8.9%+6.5%
ROCEReturn on capital employed+10.2%+7.7%
Piotroski ScoreFundamental quality 0–955
Debt / EquityFinancial leverage0.09x0.38x
Net DebtTotal debt minus cash-$412M$3.9B
Cash & Equiv.Liquid assets$3.1B$3.0B
Total DebtShort + long-term debt$2.7B$6.9B
Interest CoverageEBIT ÷ Interest expense108.44x6.91x
REGN leads this category, winning 8 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

REGN leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in REGN five years ago would be worth $14,651 today (with dividends reinvested), compared to $6,964 for BIIB. Over the past 12 months, BIIB leads with a +55.3% total return vs REGN's +17.0%. The 3-year compound annual growth rate (CAGR) favors REGN at -2.5% vs BIIB's -15.9% — a key indicator of consistent wealth creation.

MetricREGN logoREGNRegeneron Pharmac…BIIB logoBIIBBiogen Inc.
YTD ReturnYear-to-date-9.4%+6.4%
1-Year ReturnPast 12 months+17.0%+55.3%
3-Year ReturnCumulative with dividends-7.3%-40.5%
5-Year ReturnCumulative with dividends+46.5%-30.4%
10-Year ReturnCumulative with dividends+87.1%-28.5%
CAGR (3Y)Annualised 3-year return-2.5%-15.9%
REGN leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

BIIB leads this category, winning 2 of 2 comparable metrics.

BIIB is the less volatile stock with a 0.64 beta — it tends to amplify market swings less than REGN's 0.81 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BIIB currently trades 93.4% from its 52-week high vs REGN's 85.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricREGN logoREGNRegeneron Pharmac…BIIB logoBIIBBiogen Inc.
Beta (5Y)Sensitivity to S&P 5000.81x0.64x
52-Week HighHighest price in past year$821.11$202.41
52-Week LowLowest price in past year$476.49$115.25
% of 52W HighCurrent price vs 52-week peak+85.5%+93.4%
RSI (14)Momentum oscillator 0–10039.853.2
Avg Volume (50D)Average daily shares traded631K1.1M
BIIB leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

REGN leads this category, winning 1 of 1 comparable metric.

Wall Street rates REGN as "Buy" and BIIB as "Buy". Consensus price targets imply 23.3% upside for REGN (target: $866) vs 11.8% for BIIB (target: $211). REGN is the only dividend payer here at 0.49% yield — a key consideration for income-focused portfolios.

MetricREGN logoREGNRegeneron Pharmac…BIIB logoBIIBBiogen Inc.
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$865.68$211.42
# AnalystsCovering analysts4848
Dividend YieldAnnual dividend ÷ price+0.5%
Dividend StreakConsecutive years of raises10
Dividend / ShareAnnual DPS$3.41
Buyback YieldShare repurchases ÷ mkt cap+5.4%0.0%
REGN leads this category, winning 1 of 1 comparable metric.
Key Takeaway

REGN leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BIIB leads in 2 (Valuation Metrics, Risk & Volatility).

Best OverallRegeneron Pharmaceuticals, … (REGN)Leads 4 of 6 categories
Loading custom metrics...

REGN vs BIIB: Frequently Asked Questions

10 questions · data-driven answers · updated daily

01

Is REGN or BIIB a better buy right now?

For growth investors, Biogen Inc.

(BIIB) is the stronger pick with 1. 4% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 16. 9x trailing P/E (15. 2x forward), making it the more compelling value choice. Analysts rate Regeneron Pharmaceuticals, Inc. (REGN) a "Buy" — based on 48 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — REGN or BIIB?

On trailing P/E, Regeneron Pharmaceuticals, Inc.

(REGN) is the cheapest at 16. 9x versus Biogen Inc. at 21. 4x. On forward P/E, Biogen Inc. is actually cheaper at 12. 9x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — REGN or BIIB?

Over the past 5 years, Regeneron Pharmaceuticals, Inc.

(REGN) delivered a total return of +46. 5%, compared to -30. 4% for Biogen Inc. (BIIB). Over 10 years, the gap is even starker: REGN returned +87. 1% versus BIIB's -28. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — REGN or BIIB?

By beta (market sensitivity over 5 years), Biogen Inc.

(BIIB) is the lower-risk stock at 0. 64β versus Regeneron Pharmaceuticals, Inc. 's 0. 81β — meaning REGN is approximately 26% more volatile than BIIB relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 38% for Biogen Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — REGN or BIIB?

By revenue growth (latest reported year), Biogen Inc.

(BIIB) is pulling ahead at 1. 4% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: Regeneron Pharmaceuticals, Inc. grew EPS 8. 2% year-over-year, compared to -21. 1% for Biogen Inc.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — REGN or BIIB?

Regeneron Pharmaceuticals, Inc.

(REGN) is the more profitable company, earning 31. 4% net margin versus 13. 2% for Biogen Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: REGN leads at 24. 9% versus 19. 1% for BIIB. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is REGN or BIIB more undervalued right now?

On forward earnings alone, Biogen Inc.

(BIIB) trades at 12. 9x forward P/E versus 15. 2x for Regeneron Pharmaceuticals, Inc. — 2. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for REGN: 23. 3% to $865. 68.

08

Which pays a better dividend — REGN or BIIB?

In this comparison, REGN (0.

5% yield) pays a dividend. BIIB does not pay a meaningful dividend and should not be held primarily for income.

09

Is REGN or BIIB better for a retirement portfolio?

For long-horizon retirement investors, Biogen Inc.

(BIIB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 64)). Both have compounded well over 10 years (BIIB: -28. 5%, REGN: +87. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between REGN and BIIB?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: REGN is a mid-cap deep-value stock; BIIB is a mid-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform both.

Stocks Like

REGN

High-Growth Quality Leader

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 9%
  • Net Margin > 17%
Run This Screen
Stocks Like

BIIB

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 8%
Run This Screen
Custom Screen

Beat Both

Find stocks that outperform REGN and BIIB on the metrics below

Revenue Growth>
%
(REGN: 19.0% · BIIB: 1.9%)
Net Margin>
%
(REGN: 29.6% · BIIB: 13.9%)
P/E Ratio<
x
(REGN: 16.9x · BIIB: 21.4x)

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