Biotechnology
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Side-by-side financial analysisStock Comparison
RNA vs MDWD
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
RNA vs MDWD — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $218M | $152M |
| Revenue (TTM) | $37M | $14M |
| Net Income (TTM) | $-396M | $-26M |
| Gross Margin | -275.6% | 19.6% |
| Operating Margin | -11.6% | -193.6% |
| Total Debt | $4M | $9M |
| Cash & Equiv. | $270M | $5M |
RNA vs MDWD — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jun 20 | Jun 26 | Return |
|---|---|---|---|
| Atrium Therapeutics… (RNA) | 100 | 45.1 | -54.9% |
| MediWound Ltd. (MDWD) | 100 | 67.1 | -32.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: RNA vs MDWD
Each card shows where this stock fits in a portfolio — not just who wins on paper.
RNA is the clearest fit if your priority is income & stability and growth exposure.
- Dividend streak 1 yrs, beta 1.38
- Rev growth 70.9%, EPS growth -55.0%, 3Y rev CAGR 26.4%
- -55.3% 10Y total return vs MDWD's -75.6%
MDWD carries the broadest edge in this set and is the clearest fit for defensive.
- Beta 1.01, current ratio 2.33x
- -180.3% margin vs RNA's -10.8%
- Beta 1.01 vs RNA's 1.38
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 70.9% revenue growth vs MDWD's -16.1% | |
| Quality / Margins | -180.3% margin vs RNA's -10.8% | |
| Stability / Safety | Beta 1.01 vs RNA's 1.38 | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | -31.9% vs RNA's -57.2% | |
| Efficiency (ROA) | -31.9% ROA vs RNA's -71.5%, ROIC -49.5% vs -10.0% |
RNA vs MDWD — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
RNA vs MDWD — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
MDWD leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
RNA is the larger business by revenue, generating $37M annually — 2.5x MDWD's $14M. Profitability is closely matched — net margins range from -180.3% (MDWD) to -10.8% (RNA). On growth, RNA holds the edge at +11.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $37M | $14M |
| EBITDAEarnings before interest/tax | -$423M | -$26M |
| Net IncomeAfter-tax profit | -$396M | -$26M |
| Free Cash FlowCash after capex | -$416M | -$24M |
| Gross MarginGross profit ÷ Revenue | -2.8% | +19.6% |
| Operating MarginEBIT ÷ Revenue | -11.6% | -193.6% |
| Net MarginNet income ÷ Revenue | -10.8% | -180.3% |
| FCF MarginFCF ÷ Revenue | -11.3% | -167.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | +11.5% | -62.7% |
| EPS Growth (YoY)Latest quarter vs prior year | -7.8% | -2.4% |
Valuation Metrics
MDWD leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $218M | $152M |
| Enterprise ValueMkt cap + debt − cash | -$48M | $156M |
| Trailing P/EPrice ÷ TTM EPS | -2.85x | -6.64x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 11.71x | 8.94x |
| Price / BookPrice ÷ Book value/share | 1.05x | 3.64x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
RNA leads this category, winning 5 of 7 comparable metrics.
Profitability & Efficiency
MDWD delivers a -67.2% return on equity — every $100 of shareholder capital generates $-67 in annual profit, vs $-86 for RNA. RNA carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to MDWD's 0.20x.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -85.9% | -67.2% |
| ROA (TTM)Return on assets | -71.5% | -31.9% |
| ROICReturn on invested capital | -10.0% | -49.5% |
| ROCEReturn on capital employed | -9.0% | -47.0% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 |
| Debt / EquityFinancial leverage | 0.02x | 0.20x |
| Net DebtTotal debt minus cash | -$266M | $4M |
| Cash & Equiv.Liquid assets | $270M | $5M |
| Total DebtShort + long-term debt | $4M | $9M |
| Interest CoverageEBIT ÷ Interest expense | — | -3.26x |
Total Returns (Dividends Reinvested)
MDWD leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in RNA five years ago would be worth $4,846 today (with dividends reinvested), compared to $4,361 for MDWD. Over the past 12 months, MDWD leads with a -31.9% total return vs RNA's -57.2%. The 3-year compound annual growth rate (CAGR) favors MDWD at 12.2% vs RNA's 0.7% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -82.3% | -24.3% |
| 1-Year ReturnPast 12 months | -57.2% | -31.9% |
| 3-Year ReturnCumulative with dividends | +2.2% | +41.3% |
| 5-Year ReturnCumulative with dividends | -51.5% | -56.4% |
| 10-Year ReturnCumulative with dividends | -55.3% | -75.6% |
| CAGR (3Y)Annualised 3-year return | +0.7% | +12.2% |
Risk & Volatility
MDWD leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
MDWD is the less volatile stock with a 1.01 beta — it tends to amplify market swings less than RNA's 1.38 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MDWD currently trades 65.6% from its 52-week high vs RNA's 17.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.38x | 1.01x |
| 52-Week HighHighest price in past year | $73.06 | $21.26 |
| 52-Week LowLowest price in past year | $11.40 | $13.54 |
| % of 52W HighCurrent price vs 52-week peak | +17.5% | +65.6% |
| RSI (14)Momentum oscillator 0–100 | 43.3 | 38.6 |
| Avg Volume (50D)Average daily shares traded | 245K | 89K |
Analyst Outlook
RNA leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Wall Street rates RNA as "Hold" and MDWD as "Buy". Consensus price targets imply 96.1% upside for RNA (target: $25) vs 93.5% for MDWD (target: $27).
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy |
| Price TargetConsensus 12-month target | $25.00 | $27.00 |
| # AnalystsCovering analysts | 16 | 13 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | 1 | 0 |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
MDWD leads in 4 of 6 categories (Income & Cash Flow, Valuation Metrics). RNA leads in 2 (Profitability & Efficiency, Analyst Outlook).
RNA vs MDWD: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is RNA or MDWD a better buy right now?
For growth investors, Atrium Therapeutics, Inc.
(RNA) is the stronger pick with 70. 9% revenue growth year-over-year, versus -16. 1% for MediWound Ltd. (MDWD). Analysts rate MediWound Ltd. (MDWD) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — RNA or MDWD?
Over the past 5 years, Atrium Therapeutics, Inc.
(RNA) delivered a total return of -51. 5%, compared to -56. 4% for MediWound Ltd. (MDWD). Over 10 years, the gap is even starker: RNA returned -55. 3% versus MDWD's -75. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — RNA or MDWD?
By beta (market sensitivity over 5 years), MediWound Ltd.
(MDWD) is the lower-risk stock at 1. 01β versus Atrium Therapeutics, Inc. 's 1. 38β — meaning RNA is approximately 36% more volatile than MDWD relative to the S&P 500. On balance sheet safety, Atrium Therapeutics, Inc. (RNA) carries a lower debt/equity ratio of 2% versus 20% for MediWound Ltd. — giving it more financial flexibility in a downturn.
04Which is growing faster — RNA or MDWD?
By revenue growth (latest reported year), Atrium Therapeutics, Inc.
(RNA) is pulling ahead at 70. 9% versus -16. 1% for MediWound Ltd. (MDWD). On earnings-per-share growth, the picture is similar: MediWound Ltd. grew EPS 30. 7% year-over-year, compared to -55. 0% for Atrium Therapeutics, Inc.. Over a 3-year CAGR, RNA leads at 26. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — RNA or MDWD?
MediWound Ltd.
(MDWD) is the more profitable company, earning -140. 8% net margin versus -411. 9% for Atrium Therapeutics, Inc. — meaning it keeps -140. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MDWD leads at -149. 1% versus -412. 6% for RNA. At the gross margin level — before operating expenses — RNA leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — RNA or MDWD?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is RNA or MDWD better for a retirement portfolio?
For long-horizon retirement investors, MediWound Ltd.
(MDWD) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 01)). Both have compounded well over 10 years (MDWD: -75. 6%, RNA: -55. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between RNA and MDWD?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: RNA is a small-cap high-growth stock; MDWD is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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