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JBIO
IMVT logo
IMVT
RCUS logo
RCUS
PRAX logo
PRAX
KO logo
KO
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Stock Comparison

JBIO vs IMVT vs RCUS vs PRAX vs KO

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
JBIO
Jade Biosciences, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$500M
5Y Perf.-98.1%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.90B
5Y Perf.+218.1%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.40B
5Y Perf.-13.3%
PRAX
Praxis Precision Medicines, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.70B
5Y Perf.-2.8%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.61B
5Y Perf.+52.7%

JBIO vs IMVT vs RCUS vs PRAX vs KO — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
JBIO logoJBIO
IMVT logoIMVT
RCUS logoRCUS
PRAX logoPRAX
KO logoKO
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyBeverages - Non-Alcoholic
Market Cap$500M$6.90B$2.40B$7.70B$355.61B
Revenue (TTM)$0.00$0.00$236M$0.00$49.28B
Net Income (TTM)$-130M$-506M$-369M$-327M$13.70B
Gross Margin90.7%61.7%
Operating Margin-168.6%29.3%
Forward P/E25.3x
Total Debt$724K$72K$99M$110K$45.49B
Cash & Equiv.$88M$902M$222M$357M$10.27B

JBIO vs IMVT vs RCUS vs PRAX vs KOLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

JBIO
IMVT
RCUS
PRAX
KO
StockJun 21Jun 26Return
Jade Biosciences, I… (JBIO)1001.9-98.1%
Immunovant, Inc. (IMVT)100318.1+218.1%
Arcus Biosciences, … (RCUS)10086.7-13.3%
Praxis Precision Me… (PRAX)10097.2-2.8%
The Coca-Cola Compa… (KO)100152.7+52.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: JBIO vs IMVT vs RCUS vs PRAX vs KO

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: KO leads in 3 of 6 categories (5-stock set), making it the strongest pick for profitability and margin quality and dividend income and shareholder returns. Praxis Precision Medicines, Inc. is the stronger pick specifically for capital preservation and lower volatility and recent price momentum and sentiment. JBIO also leads in specific categories worth noting. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇KO emerged as the overall leader. Track its performance:
JBIO
Jade Biosciences, Inc.
The Income Pick

JBIO ranks third and is worth considering specifically for income & stability.

  • Dividend streak 1 yrs, beta 1.60
  • 141.8% revenue growth vs PRAX's -100.0%
Best for: income & stability
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT is the clearest fit if your priority is long-term compounding.

  • 237.9% 10Y total return vs KO's 121.1%
Best for: long-term compounding
RCUS
Arcus Biosciences, Inc.
The Healthcare Pick

Among these 5 stocks, RCUS doesn't own a clear edge in any measured category.

Best for: healthcare exposure
PRAX
Praxis Precision Medicines, Inc.
The Defensive Pick

PRAX is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.

  • Lower volatility, beta 1.55, Low D/E 0.0%, current ratio 10.22x
  • Beta 1.55, current ratio 10.22x
  • Beta 1.55 vs RCUS's 2.00, lower leverage
  • +491.9% vs KO's +17.2%
Best for: sleep-well-at-night and defensive
KO
The Coca-Cola Company
The Growth Play

KO carries the broadest edge in this set and is the clearest fit for growth exposure.

  • Rev growth 1.9%, EPS growth 23.6%, 3Y rev CAGR 3.7%
  • 27.8% margin vs RCUS's -156.4%
  • 2.5% yield; 56-year raise streak; the other 4 pay no meaningful dividend
  • 13.1% ROA vs IMVT's -62.2%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthJBIO logoJBIO141.8% revenue growth vs PRAX's -100.0%
Quality / MarginsKO logoKO27.8% margin vs RCUS's -156.4%
Stability / SafetyPRAX logoPRAXBeta 1.55 vs RCUS's 2.00, lower leverage
DividendsKO logoKO2.5% yield; 56-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)PRAX logoPRAX+491.9% vs KO's +17.2%
Efficiency (ROA)KO logoKO13.1% ROA vs IMVT's -62.2%

JBIO vs IMVT vs RCUS vs PRAX vs KO — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

JBIOJade Biosciences, Inc.

Segment breakdown not available.

IMVTImmunovant, Inc.

Segment breakdown not available.

RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M
PRAXPraxis Precision Medicines, Inc.
FY 2024
License
76.8%$9M
Upfront Payment
23.2%$3M
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B

JBIO vs IMVT vs RCUS vs PRAX vs KO — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLKOLAGGINGPRAX

Income & Cash Flow (Last 12 Months)

KO leads this category, winning 5 of 6 comparable metrics.

KO and PRAX operate at a comparable scale, with $49.3B and $0 in trailing revenue. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to RCUS's -156.4%. On growth, KO holds the edge at +12.1% YoY revenue growth, suggesting stronger near-term business momentum.

MetricJBIO logoJBIOJade Biosciences,…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…PRAX logoPRAXPraxis Precision …KO logoKOThe Coca-Cola Com…
RevenueTrailing 12 months$0$0$236M$0$49.3B
EBITDAEarnings before interest/tax-$134M-$532M-$391M-$357M$15.5B
Net IncomeAfter-tax profit-$130M-$506M-$369M-$327M$13.7B
Free Cash FlowCash after capex-$117M-$407M-$489M-$283M$12.6B
Gross MarginGross profit ÷ Revenue+90.7%+61.7%
Operating MarginEBIT ÷ Revenue-168.6%+29.3%
Net MarginNet income ÷ Revenue-156.4%+27.8%
FCF MarginFCF ÷ Revenue-2.1%+25.5%
Rev. Growth (YoY)Latest quarter vs prior year-39.3%+12.1%
EPS Growth (YoY)Latest quarter vs prior year-14.1%+10.5%+2.7%+18.2%
KO leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

Evenly matched — JBIO and PRAX and KO each lead in 1 of 3 comparable metrics.
MetricJBIO logoJBIOJade Biosciences,…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…PRAX logoPRAXPraxis Precision …KO logoKOThe Coca-Cola Com…
Market CapShares × price$500M$6.9B$2.4B$7.7B$355.6B
Enterprise ValueMkt cap + debt − cash$413M$6.0B$2.3B$7.3B$390.8B
Trailing P/EPrice ÷ TTM EPS-3.78x-12.14x-7.23x-19.77x27.18x
Forward P/EPrice ÷ next-FY EPS est.25.27x
PEG RatioP/E ÷ EPS growth rate2.43x
EV / EBITDAEnterprise value multiple26.39x
Price / SalesMarket cap ÷ Revenue9.70x7.42x
Price / BookPrice ÷ Book value/share1.45x7.19x4.05x6.83x10.40x
Price / FCFMarket cap ÷ FCF67.15x
Evenly matched — JBIO and PRAX and KO each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

KO leads this category, winning 6 of 9 comparable metrics.

KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-69 for RCUS. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to KO's 1.33x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs RCUS's 0/9, reflecting strong financial health.

MetricJBIO logoJBIOJade Biosciences,…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…PRAX logoPRAXPraxis Precision …KO logoKOThe Coca-Cola Com…
ROE (TTM)Return on equity-51.3%-68.2%-69.0%-43.0%+41.1%
ROA (TTM)Return on assets-47.3%-62.2%-35.3%-40.2%+13.1%
ROICReturn on invested capital-59.2%-64.1%-65.0%+15.8%
ROCEReturn on capital employed-55.4%-68.3%-42.1%-49.3%+17.3%
Piotroski ScoreFundamental quality 0–932037
Debt / EquityFinancial leverage0.00x0.00x0.16x0.00x1.33x
Net DebtTotal debt minus cash-$88M-$902M-$123M-$357M$35.2B
Cash & Equiv.Liquid assets$88M$902M$222M$357M$10.3B
Total DebtShort + long-term debt$724,000$72,000$99M$110,000$45.5B
Interest CoverageEBIT ÷ Interest expense-13.38x10.70x
KO leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — IMVT and PRAX each lead in 3 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $222 for JBIO. Over the past 12 months, PRAX leads with a +491.9% total return vs KO's +17.2%. The 3-year compound annual growth rate (CAGR) favors PRAX at 164.8% vs JBIO's -68.1% — a key indicator of consistent wealth creation.

MetricJBIO logoJBIOJade Biosciences,…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…PRAX logoPRAXPraxis Precision …KO logoKOThe Coca-Cola Com…
YTD ReturnYear-to-date+8.3%+29.8%+2.2%-6.9%+20.3%
1-Year ReturnPast 12 months+121.0%+110.9%+154.5%+491.9%+17.2%
3-Year ReturnCumulative with dividends-96.8%+55.0%+18.3%+1757.4%+47.0%
5-Year ReturnCumulative with dividends-97.8%+213.0%-3.1%-14.2%+65.6%
10-Year ReturnCumulative with dividends-97.8%+237.9%+40.0%-36.1%+121.1%
CAGR (3Y)Annualised 3-year return-68.1%+15.7%+5.8%+164.8%+13.7%
Evenly matched — IMVT and PRAX each lead in 3 of 6 comparable metrics.

Risk & Volatility

KO leads this category, winning 2 of 2 comparable metrics.

KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than RCUS's 2.00 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs JBIO's 54.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricJBIO logoJBIOJade Biosciences,…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…PRAX logoPRAXPraxis Precision …KO logoKOThe Coca-Cola Com…
Beta (5Y)Sensitivity to S&P 5001.60x1.66x2.00x1.55x-0.20x
52-Week HighHighest price in past year$27.96$36.27$28.72$366.52$84.04
52-Week LowLowest price in past year$6.57$14.32$7.91$37.19$65.35
% of 52W HighCurrent price vs 52-week peak+54.9%+92.7%+82.9%+72.7%+98.3%
RSI (14)Momentum oscillator 0–10032.557.946.531.960.6
Avg Volume (50D)Average daily shares traded826K1.9M1.1M396K12.7M
KO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

KO leads this category, winning 1 of 1 comparable metric.

Analyst consensus: JBIO as "Buy", IMVT as "Buy", RCUS as "Buy", PRAX as "Buy", KO as "Buy". Consensus price targets imply 188.1% upside for JBIO (target: $44) vs 4.2% for KO (target: $86). KO is the only dividend payer here at 2.46% yield — a key consideration for income-focused portfolios.

MetricJBIO logoJBIOJade Biosciences,…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…PRAX logoPRAXPraxis Precision …KO logoKOThe Coca-Cola Com…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$44.20$43.67$31.00$607.15$86.13
# AnalystsCovering analysts423181648
Dividend YieldAnnual dividend ÷ price+2.5%
Dividend StreakConsecutive years of raises156
Dividend / ShareAnnual DPS$2.04
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%+0.2%
KO leads this category, winning 1 of 1 comparable metric.
Key Takeaway

KO leads in 4 of 6 categories — strongest in Income & Cash Flow and Profitability & Efficiency. 2 categories are tied.

Best OverallThe Coca-Cola Company (KO)Leads 4 of 6 categories
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JBIO vs IMVT vs RCUS vs PRAX vs KO: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is JBIO or IMVT or RCUS or PRAX or KO a better buy right now?

For growth investors, The Coca-Cola Company (KO) is the stronger pick with 1.

9% revenue growth year-over-year, versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). The Coca-Cola Company (KO) offers the better valuation at 27. 2x trailing P/E (25. 3x forward), making it the more compelling value choice. Analysts rate Jade Biosciences, Inc. (JBIO) a "Buy" — based on 4 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — JBIO or IMVT or RCUS or PRAX or KO?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +213. 0%, compared to -97. 8% for Jade Biosciences, Inc. (JBIO). Over 10 years, the gap is even starker: IMVT returned +237. 9% versus JBIO's -97. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — JBIO or IMVT or RCUS or PRAX or KO?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

20β versus Arcus Biosciences, Inc. 's 2. 00β — meaning RCUS is approximately -1098% more volatile than KO relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 133% for The Coca-Cola Company — giving it more financial flexibility in a downturn.

04

Which is growing faster — JBIO or IMVT or RCUS or PRAX or KO?

By revenue growth (latest reported year), The Coca-Cola Company (KO) is pulling ahead at 1.

9% versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). On earnings-per-share growth, the picture is similar: Jade Biosciences, Inc. grew EPS 95. 2% year-over-year, compared to -32. 0% for Praxis Precision Medicines, Inc.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — JBIO or IMVT or RCUS or PRAX or KO?

The Coca-Cola Company (KO) is the more profitable company, earning 27.

3% net margin versus -142. 9% for Arcus Biosciences, Inc. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus -156. 3% for RCUS. At the gross margin level — before operating expenses — RCUS leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is JBIO or IMVT or RCUS or PRAX or KO more undervalued right now?

Analyst consensus price targets imply the most upside for JBIO: 188.

1% to $44. 20.

07

Which pays a better dividend — JBIO or IMVT or RCUS or PRAX or KO?

In this comparison, KO (2.

5% yield) pays a dividend. JBIO, IMVT, RCUS, PRAX do not pay a meaningful dividend and should not be held primarily for income.

08

Is JBIO or IMVT or RCUS or PRAX or KO better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

20), 2. 5% yield, +121. 1% 10Y return). Arcus Biosciences, Inc. (RCUS) carries a higher beta of 2. 00 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +121. 1%, RCUS: +40. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between JBIO and IMVT and RCUS and PRAX and KO?

These companies operate in different sectors (JBIO (Healthcare) and IMVT (Healthcare) and RCUS (Healthcare) and PRAX (Healthcare) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

KO pays a dividend while JBIO, IMVT, RCUS, PRAX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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