Biotechnology
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Side-by-side financial analysisStock Comparison
KLRS vs ADMA vs GRFS vs REPL vs JPM vs KO
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Drug Manufacturers - General
Biotechnology
Banks - Diversified
Beverages - Non-Alcoholic
KLRS vs ADMA vs GRFS vs REPL vs JPM vs KO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||||
|---|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Drug Manufacturers - General | Biotechnology | Banks - Diversified | Beverages - Non-Alcoholic |
| Market Cap | $81M | $1.90B | $6.46B | $733M | $896.00B | $355.61B |
| Revenue (TTM) | $0.00 | $510M | $7.45B | — | $280.33B | $49.28B |
| Net Income (TTM) | $-44M | $165M | $416M | $-315M | $57.05B | $13.70B |
| Gross Margin | — | 61.3% | 37.7% | — | 60.0% | 61.7% |
| Operating Margin | — | 42.1% | 16.9% | — | 25.9% | 29.3% |
| Forward P/E | — | 9.9x | 8.9x | — | 14.4x | 25.3x |
| Total Debt | $1M | $80M | $8.74B | $76M | $942.38B | $45.49B |
| Cash & Equiv. | $98M | $88M | $825M | $111M | $343.34B | $10.27B |
KLRS vs ADMA vs GRFS vs REPL vs JPM vs KO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Mar 25 | Jun 26 | Return |
|---|---|---|---|
| Kalaris Therapeutic… (KLRS) | 100 | 53.9 | -46.1% |
| ADMA Biologics, Inc. (ADMA) | 100 | 41.4 | -58.6% |
| Grifols, S.A. (GRFS) | 100 | 107.5 | +7.5% |
| Replimune Group, In… (REPL) | 100 | 91.1 | -8.9% |
| JPMorgan Chase & Co. (JPM) | 100 | 130.7 | +30.7% |
| The Coca-Cola Compa… (KO) | 100 | 115.4 | +15.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: KLRS vs ADMA vs GRFS vs REPL vs JPM vs KO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
KLRS carries the broadest edge in this set and is the clearest fit for sleep-well-at-night and defensive.
- Lower volatility, beta 0.81, Low D/E 1.8%, current ratio 12.23x
- Beta 0.81, current ratio 12.23x
- 100.0% revenue growth vs REPL's -39.7%
- Beta 0.81 vs ADMA's 1.11, lower leverage
ADMA is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 19.6%, EPS growth -25.9%, 3Y rev CAGR 49.0%
- 32.4% margin vs KLRS's -1.2%
- 27.4% ROA vs REPL's -72.2%, ROIC 36.0% vs -51.9%
GRFS ranks third and is worth considering specifically for income & stability.
- Dividend streak 0 yrs, beta 0.99, yield 2.7%
- Lower P/E (8.9x vs 25.3x)
- 2.7% yield, vs KO's 2.5%, (3 stocks pay no dividend)
REPL lags the leaders in this set but could rank higher in a more targeted comparison.
JPM is the clearest fit if your priority is long-term compounding and valuation efficiency.
- 465.8% 10Y total return vs ADMA's 15.3%
- PEG 0.81 vs KO's 2.26
KO doesn't hold a clear category lead here; it's more of a secondary option in this specific comparison.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 100.0% revenue growth vs REPL's -39.7% | |
| Value | Lower P/E (8.9x vs 25.3x) | |
| Quality / Margins | 32.4% margin vs KLRS's -1.2% | |
| Stability / Safety | Beta 0.81 vs ADMA's 1.11, lower leverage | |
| Dividends | 2.7% yield, vs KO's 2.5%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +56.9% vs ADMA's -62.0% | |
| Efficiency (ROA) | 27.4% ROA vs REPL's -72.2%, ROIC 36.0% vs -51.9% |
KLRS vs ADMA vs GRFS vs REPL vs JPM vs KO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
KLRS vs ADMA vs GRFS vs REPL vs JPM vs KO — Financial Metrics
Side-by-side numbers across 6 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
GRFS leads in 1 of 6 categories
ADMA leads 1 • JPM leads 1 • KO leads 1 • KLRS leads 0 • REPL leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — ADMA and KO each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
JPM and KLRS operate at a comparable scale, with $280.3B and $0 in trailing revenue. ADMA is the more profitable business, keeping 32.4% of every revenue dollar as net income compared to GRFS's 5.6%. On growth, KO holds the edge at +12.1% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||||
|---|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $510M | $7.4B | — | $280.3B | $49.3B |
| EBITDAEarnings before interest/tax | -$46M | $221M | $1.6B | -$323M | $81.4B | $15.5B |
| Net IncomeAfter-tax profit | -$44M | $165M | $416M | -$315M | $57.0B | $13.7B |
| Free Cash FlowCash after capex | -$49M | $108M | $745M | -$283M | $100.9B | $12.6B |
| Gross MarginGross profit ÷ Revenue | — | +61.3% | +37.7% | — | +60.0% | +61.7% |
| Operating MarginEBIT ÷ Revenue | — | +42.1% | +16.9% | — | +25.9% | +29.3% |
| Net MarginNet income ÷ Revenue | — | +32.4% | +5.6% | — | +20.4% | +27.8% |
| FCF MarginFCF ÷ Revenue | — | +21.2% | +10.0% | — | +36.0% | +25.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -0.3% | -3.2% | — | — | +12.1% |
| EPS Growth (YoY)Latest quarter vs prior year | +81.7% | +72.7% | +25.3% | +2.5% | +16.0% | +18.2% |
Valuation Metrics
GRFS leads this category, winning 5 of 7 comparable metrics.
Valuation Metrics
At 11.6x trailing earnings, GRFS trades at a 57% valuation discount to KO's 27.2x P/E. Adjusting for growth (PEG ratio), JPM offers better value at 0.90x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||||
|---|---|---|---|---|---|---|
| Market CapShares × price | $81M | $1.9B | $6.5B | $733M | $896.0B | $355.6B |
| Enterprise ValueMkt cap + debt − cash | -$16M | $1.9B | $15.6B | $698M | $1.50T | $390.8B |
| Trailing P/EPrice ÷ TTM EPS | -1.52x | 13.68x | 11.59x | -2.89x | 16.00x | 27.18x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 9.92x | 8.94x | — | 14.40x | 25.27x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | 0.90x | 2.43x |
| EV / EBITDAEnterprise value multiple | — | 9.50x | 8.34x | — | 18.36x | 26.39x |
| Price / SalesMarket cap ÷ Revenue | — | 3.73x | 0.77x | — | 3.20x | 7.42x |
| Price / BookPrice ÷ Book value/share | 0.84x | 4.21x | 0.59x | 1.72x | 2.47x | 10.40x |
| Price / FCFMarket cap ÷ FCF | — | 68.40x | 7.44x | — | 8.88x | 67.15x |
Profitability & Efficiency
ADMA leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-103 for REPL. KLRS carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs REPL's 2/9, reflecting strong financial health.
| Metric | ||||||
|---|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -72.8% | +39.0% | +5.4% | -102.7% | +15.9% | +41.1% |
| ROA (TTM)Return on assets | -43.5% | +27.4% | +2.1% | -72.2% | +1.3% | +13.1% |
| ROICReturn on invested capital | — | +36.0% | +5.4% | -51.9% | +4.5% | +15.8% |
| ROCEReturn on capital employed | -41.0% | +38.8% | +6.4% | -55.9% | +8.9% | +17.3% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 5 | 6 | 2 | 5 | 7 |
| Debt / EquityFinancial leverage | 0.02x | 0.17x | 1.15x | 0.18x | 2.60x | 1.33x |
| Net DebtTotal debt minus cash | -$97M | -$8M | $7.9B | -$35M | $599.0B | $35.2B |
| Cash & Equiv.Liquid assets | $98M | $88M | $825M | $111M | $343.3B | $10.3B |
| Total DebtShort + long-term debt | $1M | $80M | $8.7B | $76M | $942.4B | $45.5B |
| Interest CoverageEBIT ÷ Interest expense | -31.98x | 50.85x | 2.02x | -48.62x | 0.74x | 10.70x |
Total Returns (Dividends Reinvested)
JPM leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ADMA five years ago would be worth $44,620 today (with dividends reinvested), compared to $2,561 for REPL. Over the past 12 months, KLRS leads with a +56.9% total return vs ADMA's -62.0%. The 3-year compound annual growth rate (CAGR) favors JPM at 33.6% vs REPL's -27.7% — a key indicator of consistent wealth creation.
| Metric | ||||||
|---|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -47.8% | -54.1% | -17.3% | -0.2% | -0.5% | +20.3% |
| 1-Year ReturnPast 12 months | +56.9% | -62.0% | -13.0% | -10.2% | +21.8% | +17.2% |
| 3-Year ReturnCumulative with dividends | -52.5% | +112.1% | -11.4% | -62.1% | +138.2% | +47.0% |
| 5-Year ReturnCumulative with dividends | -52.5% | +346.2% | -57.5% | -74.4% | +118.2% | +65.6% |
| 10-Year ReturnCumulative with dividends | -52.5% | +15.3% | -44.2% | -41.4% | +465.8% | +121.1% |
| CAGR (3Y)Annualised 3-year return | -22.0% | +28.5% | -3.9% | -27.7% | +33.6% | +13.7% |
Risk & Volatility
KO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than ADMA's 1.11 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs KLRS's 36.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||||
|---|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.81x | 1.11x | 0.99x | 0.84x | 0.94x | -0.20x |
| 52-Week HighHighest price in past year | $11.88 | $22.20 | $11.14 | $13.24 | $337.25 | $84.04 |
| 52-Week LowLowest price in past year | $2.14 | $7.21 | $7.26 | $1.50 | $262.71 | $65.35 |
| % of 52W HighCurrent price vs 52-week peak | +36.4% | +37.0% | +68.6% | +67.1% | +95.1% | +98.3% |
| RSI (14)Momentum oscillator 0–100 | 39.7 | 44.9 | 41.6 | 63.4 | 59.1 | 60.6 |
| Avg Volume (50D)Average daily shares traded | 86K | 5.0M | 551K | 8.9M | 7.0M | 12.7M |
Analyst Outlook
Evenly matched — GRFS and KO each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: ADMA as "Buy", GRFS as "Buy", REPL as "Buy", JPM as "Buy", KO as "Buy". Consensus price targets imply 331.2% upside for KLRS (target: $19) vs 4.2% for KO (target: $86). For income investors, GRFS offers the higher dividend yield at 2.73% vs JPM's 1.86%.
| Metric | ||||||
|---|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $18.67 | $21.00 | — | $14.00 | $339.75 | $86.13 |
| # AnalystsCovering analysts | — | 10 | 8 | 15 | 61 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | — | +2.7% | — | +1.9% | +2.5% |
| Dividend StreakConsecutive years of raises | — | 1 | 0 | 0 | 15 | 56 |
| Dividend / ShareAnnual DPS | — | — | $0.18 | — | $5.95 | $2.04 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +1.7% | +2.2% | 0.0% | +3.9% | +0.2% |
GRFS leads in 1 of 6 categories (Valuation Metrics). ADMA leads in 1 (Profitability & Efficiency). 2 tied.
KLRS vs ADMA vs GRFS vs REPL vs JPM vs KO: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is KLRS or ADMA or GRFS or REPL or JPM or KO a better buy right now?
For growth investors, ADMA Biologics, Inc.
(ADMA) is the stronger pick with 19. 6% revenue growth year-over-year, versus 0. 2% for Grifols, S. A. (GRFS). Grifols, S. A. (GRFS) offers the better valuation at 11. 6x trailing P/E (8. 9x forward), making it the more compelling value choice. Analysts rate ADMA Biologics, Inc. (ADMA) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — KLRS or ADMA or GRFS or REPL or JPM or KO?
On trailing P/E, Grifols, S.
A. (GRFS) is the cheapest at 11. 6x versus The Coca-Cola Company at 27. 2x. On forward P/E, Grifols, S. A. is actually cheaper at 8. 9x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: JPMorgan Chase & Co. wins at 0. 81x versus The Coca-Cola Company's 2. 26x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — KLRS or ADMA or GRFS or REPL or JPM or KO?
Over the past 5 years, ADMA Biologics, Inc.
(ADMA) delivered a total return of +346. 2%, compared to -74. 4% for Replimune Group, Inc. (REPL). Over 10 years, the gap is even starker: JPM returned +465. 8% versus KLRS's -52. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — KLRS or ADMA or GRFS or REPL or JPM or KO?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
20β versus ADMA Biologics, Inc. 's 1. 11β — meaning ADMA is approximately -656% more volatile than KO relative to the S&P 500. On balance sheet safety, Kalaris Therapeutics Inc (KLRS) carries a lower debt/equity ratio of 2% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.
05Which is growing faster — KLRS or ADMA or GRFS or REPL or JPM or KO?
By revenue growth (latest reported year), ADMA Biologics, Inc.
(ADMA) is pulling ahead at 19. 6% versus 0. 2% for Grifols, S. A. (GRFS). On earnings-per-share growth, the picture is similar: Grifols, S. A. grew EPS 147. 8% year-over-year, compared to -25. 9% for ADMA Biologics, Inc.. Over a 3-year CAGR, ADMA leads at 49. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — KLRS or ADMA or GRFS or REPL or JPM or KO?
ADMA Biologics, Inc.
(ADMA) is the more profitable company, earning 28. 8% net margin versus 0. 0% for Replimune Group, Inc. — meaning it keeps 28. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ADMA leads at 37. 5% versus 0. 0% for REPL. At the gross margin level — before operating expenses — KO leads at 61. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is KLRS or ADMA or GRFS or REPL or JPM or KO more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, JPMorgan Chase & Co. (JPM) is the more undervalued stock at a PEG of 0. 81x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Grifols, S. A. (GRFS) trades at 8. 9x forward P/E versus 25. 3x for The Coca-Cola Company — 16. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for KLRS: 331. 2% to $18. 67.
08Which pays a better dividend — KLRS or ADMA or GRFS or REPL or JPM or KO?
In this comparison, GRFS (2.
7% yield), KO (2. 5% yield), JPM (1. 9% yield) pay a dividend. KLRS, ADMA, REPL do not pay a meaningful dividend and should not be held primarily for income.
09Is KLRS or ADMA or GRFS or REPL or JPM or KO better for a retirement portfolio?
For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
20), 2. 5% yield, +121. 1% 10Y return). Both have compounded well over 10 years (KO: +121. 1%, ADMA: +15. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between KLRS and ADMA and GRFS and REPL and JPM and KO?
These companies operate in different sectors (KLRS (Healthcare) and ADMA (Healthcare) and GRFS (Healthcare) and REPL (Healthcare) and JPM (Financial Services) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: KLRS is a small-cap quality compounder stock; ADMA is a small-cap high-growth stock; GRFS is a small-cap deep-value stock; REPL is a small-cap quality compounder stock; JPM is a large-cap deep-value stock; KO is a large-cap quality compounder stock. GRFS, JPM, KO pay a dividend while KLRS, ADMA, REPL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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