Last 21 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q2 '25 | Q4 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -3.76 | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 2037.00 | — | 176.97 | — | — | 41.54 | 32.93 | 1.50 | 1.46 | 4.24 | 4.10 | 4.59 | 15.57 |
| — | — | +437.4% | — | — | +879.0% | +703.4% | -67.5% | -90.6% | -47.1% | -85.6% | -93.7% | -91.9% | |
| P/B Ratio | 2.55 | 1.94 | 1.45 | 1.91 | 1.75 | 0.96 | 0.76 | 0.62 | 0.61 | 0.55 | 0.53 | 0.64 | 1.08 |
| — | +101.8% | +89.9% | +205.9% | +185.7% | +75.1% | +43.7% | -2.4% | -43.5% | -69.5% | -83.5% | -69.8% | -61.4% | |
| P/FCF | — | — | — | — | — | — | — | — | — | 0.73 | 4.59 | 6.30 | — |
| — | — | — | — | — | — | — | — | — | -83.8% | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q2 '25 | Q4 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | -797.5% | — | -797.5% | — | — | -4.3% | 100.0% | — | 100.0% | 0.9% | 100.0% | 50.0% | 100.0% |
| — | — | -897.5% | — | — | -575.4% | 0.0% | — | 0.0% | -98.2% | 0.0% | 0.0% | 0.0% | |
| Operating Margin | -34835.4% | — | -25958.9% | — | — | -2288.8% | -2288.8% | -29.2% | -29.2% | -667.6% | -667.6% | -1225.4% | -1225.4% |
| — | — | -1034.2% | — | — | -242.8% | -242.8% | +97.6% | +97.6% | -68.8% | -68.8% | +55.6% | +55.6% | |
| Net Margin | -32386.4% | — | -24144.7% | — | — | -1818.9% | -1818.9% | -23.8% | -23.8% | -602.1% | -602.1% | -1214.4% | -1214.4% |
| — | — | -1227.4% | — | — | -202.1% | -202.1% | +98.0% | +98.0% | -47.5% | -47.5% | +55.6% | +55.7% |
| Metric | TTM | Q2 '25 | Q4 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -55.2% | -30.6% | -46.5% | -15.0% | -13.4% | -10.5% | -9.7% | -2.5% | -2.5% | -19.5% | -16.5% | -42.3% | -17.7% |
| — | -190.6% | -380.9% | -505.8% | -440.2% | +46.0% | +41.4% | +94.1% | +86.0% | +15.1% | -57.3% | -111.7% | +54.0% | |
| ROA | -32.6% | -17.3% | -26.2% | -8.4% | -7.9% | -6.4% | -5.9% | -1.5% | -1.4% | -10.6% | -9.8% | -26.7% | -12.9% |
| — | -170.6% | -343.7% | -455.9% | -450.2% | +39.6% | +39.5% | +94.3% | +89.0% | +44.0% | -10.6% | -56.3% | -5.1% | |
| ROIC | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
The current ratio has weakened 36.4% YoY to 2.29x, tightening the short-term liquidity position. Debt/Equity has declined for 3 consecutive quarters, reflecting a deleveraging trend.
| Metric | TTM | Q2 '25 | Q4 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.37 | 0.18 | 0.37 | 0.37 | 0.37 | 0.32 | 0.32 | 0.30 | 0.30 | 0.34 | 0.34 | 0.15 | 0.15 |
| — | -42.8% | +15.8% | +20.5% | +20.5% | -6.1% | -6.1% | +102.1% | +102.1% | +603.7% | +603.7% | +266.0% | +266.0% | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 2.30 | 2.29 | 2.30 | 2.50 | 2.50 | 3.61 | 3.61 | 3.40 | 3.40 | 2.71 | 2.71 | 3.10 | 3.10 |
| — | -36.4% | -36.3% | -26.5% | -26.5% | +33.0% | +33.0% | +9.8% | +9.8% | -56.5% | -56.5% | -57.4% | -57.4% | |
| Quick Ratio | 2.30 | 2.29 | 2.30 | 2.50 | 2.50 | 3.61 | 3.61 | 3.40 | 3.40 | 2.71 | 2.71 | 3.10 | 3.10 |
| — | -36.4% | -36.3% | -26.5% | -26.5% | +33.0% | +33.0% | +9.8% | +9.8% | -56.5% | -56.5% | -57.4% | -57.4% | |
| Interest Coverage | -42.20 | -49.27 | -63.25 | -21.39 | — | -17.10 | — | -4.40 | — | -37.36 | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 21 years · Updated daily
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Adagene Inc.'s current P/E is -3.8x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Adagene Inc.'s current operating margin is -34835.4%. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Adagene Inc.'s business trajectory between earnings reports.