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BCYCBicycle Therapeutics plc
$3.60$250M
Overview & Tools
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Valuation & Forecasts
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Price & Analyst Data
Analyst TargetsPrice History
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BCYC logo

Bicycle Therapeutics plc

BCYC
NASDAQ · Biotechnology
$3.60
At close - Sep 23, 4:00 PM EDT - USD
Market Cap$250M
P/E-1.1x
52W High$9.16
Volume374.05K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q1

Clinical Development Costs Outpace Milestone Revenue

Bicycle Therapeutics remains a high-risk, binary-outcome biotechnology play heavily reliant on its proprietary peptide platform to drive future value. While the company maintains a robust liquidity position, the lack of sustainable commercial revenue and persi...

GrowthMixed
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

BCYC price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

7/12 Beats

EPS beat 7 of last 12 quarters

02

Valuation risk

-106% Peers

P/E is 106% below peer median

03

Market leadership

RS 18 · Lag

Laggard (Underperforming 82% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Oct 30

Market performance

Price History →

Trailing total returns as of 9/24/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
BCYC-46.11%
S&P 500 (^GSPC)+12.39%
1-Year Return
BCYC-49.22%
S&P 500 (^GSPC)+15.77%
3-Year Return
BCYC-82.13%
S&P 500 (^GSPC)+74.46%
5-Year Return
BCYC-91.72%
S&P 500 (^GSPC)+69.47%

Growth & profitability

Annual revenue & EPS trend
Revenue
$73M+105.8% YoY
Net income
-$219M-29.5% YoY
Free cash flow
-$253M-52.2% YoY
Operating margin
-341.3%+253.7 pts YoY
ROIC (TTM)-
Avg ROIC 5Y-
ROE (TTM)-31.2%
Piotroski Score2 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate7/12 (58%)
Revenue Beat Rate5/12 (42%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Jul 30, 2026
-$0.72-27.6%
vs -$0.56
$629,000-85.1%
vs $4M
Q2 2026
Apr 30, 2026
-$0.87-67.3%
vs -$0.52
$887,000-88.2%
vs $8M
Q2 2026
Mar 17, 2026
-$0.29+69.1%
vs -$0.94
$48M+581.6%
vs $7M
Q4 2025
Oct 30, 2025
-$0.85+22.0%
vs -$1.09
$12M+65.8%
vs $7M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

2 Stories
PYMNTS·Aug 3, 2026
Visa Inks $2.4 Billion Deal to Acquire Fraud Prevention Firm BioCatch

Visa is set to acquire Israel-based fraud intelligence company BioCatch for $2.4 billion. The all-cash deal, announced Monday (Aug. 3) aims to complement Visa's cyber, fraud, risk and security solutions and help clients protect themselves and customers from a growing range of fraud-related threats.

Business Wire·Jul 30, 2026
Bicycle Therapeutics Reports Recent Business Progress and Second Quarter 2026 Financial Results

CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) technology, today reported financial results for the second quarter ended June 30, 2026, and provided recent corporate updates. “We are pleased with the progress we made during the second quarter. Our financial discipline with refined focus on nuzefatide pevedotin and our nex.

Filtered for Bicycle Therapeutics plcMore Headlines
04

Compare before deciding

Benchmark BCYC against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Bicycle Therapeutics plc (BCYC)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
BCYC logoBCYCBicycle Therapeutics plcCurrent
$3.60$249.82M-1.14105.77%-301.66%-31.21%—
PEPG logoPEPGPepGen Inc.
$2.72$188.14M-1.28——-51.01%—
CYCN logoCYCNCyclerion Therapeutics, Inc.
$23.52$15.73M-3.083.7%-353%-87.96%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$282.12$7.87B-20.93-100%—-34.15%—
TERN logoTERNTerns Pharmaceuticals, Inc.
$52.95$4.77B-51.41——-20.02%—
AGIO logoAGIOAgios Pharmaceuticals, Inc.
$34.19$2.03B-4.8048.03%-418.24%-35.67%—

Compare BCYC vs Peers

Bicycle Therapeutics plc (BCYC) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PEPG

Most directly comparable listed peer for BCYC.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare BCYC against a more recognizable public peer.

Peer Set

Compare Top 5

vs PEPG, CYCN, PRAX, TERN

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

BCYC SEC Filings & Documents

Bicycle Therapeutics plc (BCYC) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jul 30, 2026·SEC

Material company update

Jun 18, 2026·SEC

Material company update

May 21, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 17, 2026·SEC

FY 2025

Feb 25, 2025·SEC

FY 2024

Feb 20, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Jul 30, 2026·SEC

FY 2026

Apr 30, 2026·SEC

FY 2025

Oct 30, 2025·SEC

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BCYC Frequently Asked Questions

Bicycle Therapeutics plc (BCYC) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Bicycle Therapeutics plc's revenue?

Bicycle Therapeutics plc (BCYC) reported $61.2M in revenue for fiscal year 2025.

How fast is Bicycle Therapeutics plc growing?

Bicycle Therapeutics plc (BCYC) grew revenue by 105.8% over the past year. This is strong growth.

Is BCYC profitable?

Bicycle Therapeutics plc (BCYC) reported a net loss of $190.4M for fiscal year 2025.

Dividend & Returns
What is BCYC's return on equity?

Bicycle Therapeutics plc (BCYC) has a return on equity (ROE) of -31.2%. Negative ROE indicates the company is unprofitable.

What is Bicycle Therapeutics plc's free cash flow?

Bicycle Therapeutics plc (BCYC) had negative free cash flow of $205.6M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in BCYC back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →