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BCYCBicycle Therapeutics plc
$3.61$251M
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
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Income StatementBalance SheetCash FlowRatios & Margins
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P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
Discovery & Screens
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BCYC logo

Bicycle Therapeutics plc

BCYC
NASDAQ · Oncology Biotech
$3.61
At close - Nov 6, 4:00 PM EST - USD
Market Cap$251M
P/E-1.8x
52W High$7.83
Volume235.65K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q3

Lumpy Collaboration Revenue Masks Persistent Cash Burn Risk

Bicycle Therapeutics' reported revenue is highly irregular, swinging from $887.0K in 2026Q1 to $34.1M in 2026Q3, which suggests the recent 190.2% growth may reflect a single collaboration event rather than a durable commercial trajectory.

GrowthMixed
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

BCYC price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

8/12 Beats

EPS beat 8 of last 12 quarters

02

Valuation risk

-104% Peers

P/E is 104% below peer median

03

Market leadership

RS 30 · Lag

Laggard (Underperforming 70% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Jan 29

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
BCYC-45.96%
S&P 500 (^GSPC)+7.63%
1-Year Return
BCYC-44.55%
S&P 500 (^GSPC)+9.69%
3-Year Return
BCYC-75.43%
S&P 500 (^GSPC)+72.02%
5-Year Return
BCYC-93.84%
S&P 500 (^GSPC)+59.82%

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
$73M+105.8% YoY
Net income FY25
-$219M-29.5% YoY
Free cash flow FY25
-$253M-52.2% YoY
Operating margin FY25
-341.3%+253.7 pts YoY
ROIC (FY25)-
Avg ROIC 5Y-
ROE (TTM)-26%
Piotroski Score2 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate8/12 (67%)
Revenue Beat Rate6/12 (50%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Oct 29, 2026
-$0.15+50.0%
vs -$0.30
$34M+178.7%
vs $12M
Q3 2026
Jul 30, 2026
-$0.72-27.6%
vs -$0.56
$629,000-85.1%
vs $4M
Q2 2026
Apr 30, 2026
-$0.87-67.3%
vs -$0.52
$887,000-88.2%
vs $8M
Q2 2026
Mar 17, 2026
-$0.29+69.1%
vs -$0.94
$48M+581.6%
vs $7M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

3 Stories
Defense World·Oct 22, 2026
Bicycle Therapeutics PLC Sponsored ADR (NASDAQ:BCYC) Stock Now Rated “Hold” by Wall Street Brokerages

Shares of Bicycle Therapeutics PLC Sponsored ADR (NASDAQ: BCYC - Get Free Report) have been assigned a consensus recommendation of "Hold" from the ten brokerages that are presently covering the firm, Marketbeat.com reports. Two research analysts have rated the stock with a sell recommendation, three have issued a hold recommendation and five have assigned a buy

Defense World·Sep 21, 2026
Head-To-Head Survey: Celldex Therapeutics (NASDAQ:CLDX) & Bicycle Therapeutics (NASDAQ:BCYC)

Celldex Therapeutics (NASDAQ: CLDX - Get Free Report) and Bicycle Therapeutics (NASDAQ: BCYC - Get Free Report) are both healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their analyst recommendations, risk, institutional ownership, profitability, earnings, dividends and valuation. Analyst Ratings This is a breakdown of recent

Defense World·Sep 21, 2026
Financial Review: Intellia Therapeutics (NASDAQ:NTLA) vs. Bicycle Therapeutics (NASDAQ:BCYC)

Bicycle Therapeutics (NASDAQ: BCYC - Get Free Report) and Intellia Therapeutics (NASDAQ: NTLA - Get Free Report) are both small-cap healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their valuation, analyst recommendations, institutional ownership, earnings, dividends, profitability and risk. Institutional and Insider Ownership 86.2% of Bicycle

Filtered for Bicycle Therapeutics plcMore Headlines
04

Compare before deciding

Benchmark BCYC against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Bicycle Therapeutics plc (BCYC)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
BCYC logoBCYCBicycle Therapeutics plcCurrent
$3.61$250.51M-1.78105.77%-169.75%-26.02%—
PEPG logoPEPGPepGen Inc.
$2.47$170.85M-2.38——-51.01%—
KRSA logoKRSAKorsana Biosciences, Inc.
$31.05$18.86M-2.813.7%-353%-87.96%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$277.62$7.74B-23.85-100%—-34.15%—
AGIO logoAGIOAgios Pharmaceuticals, Inc.
$29.41$1.75B-4.7148.03%-264.76%-34.63%—
IMVT logoIMVTImmunovant, Inc.
$30.53$6.3B-11.66—-7585.86%-69.59%—

Compare BCYC vs Peers

Bicycle Therapeutics plc (BCYC) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PEPG

Most directly comparable listed peer for BCYC.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare BCYC against a more recognizable public peer.

Peer Set

Compare Top 5

vs PEPG, KRSA, PRAX, AGIO

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

BCYC SEC Filings & Documents

Bicycle Therapeutics plc (BCYC) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Oct 29, 2026·SEC

Material company update

Jul 30, 2026·SEC

Material company update

Jun 18, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 17, 2026·SEC

FY 2025

Feb 25, 2025·SEC

FY 2024

Feb 20, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Oct 29, 2026·SEC

FY 2026

Jul 30, 2026·SEC

FY 2026

Apr 30, 2026·SEC

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BCYC Frequently Asked Questions

Bicycle Therapeutics plc (BCYC) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Bicycle Therapeutics plc's revenue?

Bicycle Therapeutics plc (BCYC) reported $83.5M in revenue over the trailing twelve months. Revenue was $72.6M in fiscal year 2025.

How fast is Bicycle Therapeutics plc growing?

Bicycle Therapeutics plc (BCYC) grew revenue by 194.7% over the trailing twelve months, compared with the twelve months before.

Is BCYC profitable?

No. Bicycle Therapeutics plc (BCYC) reported a net loss of $141.8M over the trailing twelve months.

Dividend & Returns
What is BCYC's return on equity?

Bicycle Therapeutics plc (BCYC) had a return on equity (ROE) of -26.0% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Bicycle Therapeutics plc's free cash flow?

Bicycle Therapeutics plc (BCYC) had negative free cash flow of $174.4M over the trailing twelve months.

What if you invested $1,000 in BCYC back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →