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SMMT logoSummit Therapeutics Inc.(SMMT)Earnings, Financials & Key Ratios

SMMT•NASDAQ
$17.85
$13.84B mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryVaccines and Infectious Disease
AboutSummit Therapeutics Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines to treat infectious diseases in the United States and Latin America. It conducts clinical programs focusing on Clostridioides difficile infection (CDI). The company's lead product candidate is ridinilazole, an orally administered small molecule antibiotic that is in Phase III clinical trials for the treatment of CDI. It also offers SMT-738, for combating multidrug resistant infections primarily carbapenem-resistant Enterobacteriaceae infections; and DDS-04 series for the potential treatment of infections caused by the Enterobacteriaceae. The company was founded in 2003 and is based in Cambridge, Massachusetts.Show more
  • Revenue$0
  • EBITDA-$1.09B-463.6%
  • Net Income-$1.08B-387.8%
  • EPS (Diluted)-1.44-364.5%
  • ROE-206.1%-117.2%
  • ROIC-220.17%-180.3%
  • Debt/Equity0.03+70.8%
Analysis→Technical→

SMMT Key Insights

Summit Therapeutics Inc. (SMMT) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free

✗Weaknesses

  • ✗Profits declining 82.9% over 5 years
  • ✗Weak Piotroski F-Score: 1/9
  • ✗Low quality earnings: Net income not backed by cash flow
  • ✗Trading more than 30% below 52-week high
  • ✗Expensive at 20.3x book value
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

SMMT Price & Volume

Summit Therapeutics Inc. (SMMT) stock price & volume — 10-year historical chart

Loading chart...

SMMT Growth Metrics

Summit Therapeutics Inc. (SMMT) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-400.96%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-376.62%

Return on Capital

10 Years-72.79%
5 Years-84.63%
3 Years-99.9%
Last Year-204.17%

SMMT Recent Earnings

Summit Therapeutics Inc. (SMMT) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 4/12 qtrs (44%)
Q2 2026Latest
Apr 30, 2026
EPS
$0.24
Est $0.27
+10.9%
Revenue
—
Est $54,420
Q1 2026
Feb 23, 2026
EPS
$0.29
Est $0.10
-182.5%
Revenue
—
Est $57M
Q4 2025
Oct 20, 2025
EPS
$0.31
Est $0.18
-76.4%
Revenue
—
Est $77M
Q3 2025
Aug 11, 2025
EPS
$0.76
Est $0.09
-736.9%
Revenue
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestApr 30, 2026
$0.24vs $0.27+10.9%
—vs $54,420
Q1 2026Feb 23, 2026
$0.29vs $0.10-182.5%
—vs $57M
Q4 2025Oct 20, 2025
$0.31vs $0.18-76.4%
—vs $77M
Q3 2025Aug 11, 2025
$0.76vs $0.09-736.9%
—
Based on last 12 quarters of dataView full earnings history →

SMMT Peer Comparison

Summit Therapeutics Inc. (SMMT) competitors in Vaccines and Infectious Disease — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
KYMR logoKYMRKymera Therapeutics, Inc.Direct Competitor7.04B86.26-23.38-16.72%-6.12%-25.02%0.05
RVMD logoRVMDRevolution Medicines, Inc.Direct Competitor29.76B151.07-25.39-69.35%0.10
TNGX logoTNGXTango Therapeutics, Inc.Direct Competitor3.21B23.62-27.1548.29%-162.85%-50.3%0.10
NUVL logoNUVLNuvalent, Inc.Direct Competitor6.92B104.26-26.53-45.12%
KRYS logoKRYSKrystal Biotech, Inc.Direct Competitor8.5B288.9042.2433.94%53.92%19.25%2.22%0.01
EXEL logoEXELExelixis, Inc.Product Competitor12.37B48.7017.526.98%35.08%40.21%6.83%0.08
MGNX logoMGNXMacroGenics, Inc.Product Competitor190.59M3.01-2.550.78%-49.91%-120.2%0.66
IMVT logoIMVTImmunovant, Inc.Product Competitor5.83B28.67-10.50-47.07%0.00

Compare SMMT vs Peers

Summit Therapeutics Inc. (SMMT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs KYMR

Most directly comparable listed peer for SMMT.

Scale Benchmark

vs AZN

Larger-name benchmark to compare SMMT against a more recognizable public peer.

Peer Set

Compare Top 5

vs KYMR, RVMD, TNGX, NUVL

SMMT Income Statement

Summit Therapeutics Inc. (SMMT) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemJan'18Jan'19Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue14.17M57.09M632.02K860K1.81M704.29K0000
Revenue Growth %391.94%302.94%-98.89%36.07%110.35%-61.07%-100%---
Cost of Goods Sold97.67K24.92K155.4K002.51M2.05M15.01M037K
COGS % of Revenue0.69%0.04%24.59%--356.95%----
Gross Profit
14.17M▲ 0%
56.39M▲ 298.0%
611.87K▼ 98.9%
860K▲ 40.6%
1.81M▲ 110.3%
-1.81M▼ 200.1%
-2.05M▼ 13.3%
-15.01M▼ 632.0%
0▲ 100.0%
-37K▲ 0%
Gross Margin %100%98.77%96.81%100%100%-256.99%----
Gross Profit Growth %391.94%298%-98.91%40.55%110.35%-200.06%-13.26%-632.05%100%-
Operating Expenses54.13M51.67M23.24M54.05M88M77.49M87.69M226M1.09B1.22B
OpEx % of Revenue382.08%90.52%3676.54%6285.23%4864.29%11002.92%----
Selling, General & Admin13.71M17.01M9.3M19.23M23.61M26.7M28.21M60.53M556.7M603.67M
SG&A % of Revenue96.8%29.8%1471.32%2236.28%1305.2%3791.03%----
Research & Development41.01M49.07M32.78M52.02M85.35M52.35M59.47M150.78M537.67M619.03M
R&D % of Revenue289.43%85.95%5187.1%6049.3%4718.19%7432.96%----
Other Operating Expenses-587.47K-14.41M-18.85M-17.2M-20.97M-1.56M014.69M00
Operating Income
-25.83M▲ 0%
5.39M▲ 120.9%
-42.76M▼ 893.6%
-71.65M▼ 67.5%
-86.19M▼ 20.3%
-79.3M▲ 8.0%
-89.74M▼ 13.2%
-211.3M▼ 135.5%
-1.09B▼ 417.9%
-1.03B▲ 0%
Operating Margin %-182.31%9.44%-6766.4%-8330.93%-4764.29%-11259.77%----
Operating Income Growth %16.86%120.86%-893.56%-67.54%-20.29%7.99%-13.16%-135.47%-417.91%-
EBITDA-25.43M7.34M-41.37M-69.64M-83.73M-78.04M-89.58M-194.16M-1.09B-1.03B
EBITDA Margin %-179.48%12.86%-6546.15%-8098.02%-4628.58%-11080.44%----
EBITDA Growth %17.95%128.87%-663.58%-68.33%-20.23%6.8%-14.79%-116.74%-463.58%-310.64%
D&A (Non-Cash Add-back)400K1.95M1.39M2M2.46M1.26M155.32K17.15M146K121K
EBIT-26.74M9.7M-22.62M-52.66M-88.36M-79.3M-69.61M-230M-1.08B-1.02B
Net Interest Income10.1K-615K-28.18K-251K-242K-2.89M-6.06M4.78M02.98M
Interest Income10.1K5K4.34K4K178.95K1.51M10.4M13.47M02.98M
Interest Expense0620K32.52K255K281K4.4M16.46M8.69M00
Other Income/Expense1.91M3.69M14.36M9.37M-2.42M-4M-526.14M4.7M14.84M10.9M
Pretax Income
-23.92M▲ 0%
9.08M▲ 138.0%
-28.41M▼ 412.8%
-62.27M▼ 119.2%
-88.6M▼ 42.3%
-83.31M▲ 6.0%
-615.87M▼ 639.3%
-221.31M▲ 64.1%
-1.08B▼ 387.8%
-1.21B▲ 0%
Pretax Margin %-168.83%15.91%-4494.82%-7241.05%-4897.84%-11828.14%----
Income Tax-3.47M-1.79M29.65K-213K-15.21M-4.52M-946K000
Effective Tax Rate %14.53%-19.66%-0.1%0.34%17.16%5.43%0.15%0%0%0%
Net Income
-28.53M▲ 0%
10.87M▲ 138.1%
-23.88M▼ 319.7%
-52.7M▼ 120.6%
-88.6M▼ 68.1%
-78.78M▲ 11.1%
-614.93M▼ 680.5%
-221.31M▲ 64.0%
-1.08B▼ 387.8%
-1.21B▲ 0%
Net Margin %-201.39%19.04%-3779.01%-6127.56%-4897.84%-11185.94%----
Net Income Growth %-25.61%138.09%-319.74%-120.64%-68.13%11.08%-680.54%64.01%-387.81%-400.96%
Net Income (Continuing)-20.16M10.87M-23.99M-52.7M-88.6M-78.78M-614.93M-221.31M-1.08B-1.21B
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)
-0.28▲ 0%
0.11▲ 139.3%
-0.73▼ 763.6%
-0.76▼ 4.1%
-0.96▼ 26.3%
-0.41▲ 57.3%
-0.99▼ 141.5%
-0.31▲ 68.7%
-1.44▼ 364.5%
-1.56▲ 0%
EPS Growth %20%139.29%-763.64%-4.11%-26.32%57.29%-141.46%68.69%-364.52%-376.62%
EPS (Basic)-0.310.11-0.73-0.76-0.96-0.41-0.99-0.31-1.44-
Diluted Shares Outstanding65.43M86.14M32.83M69.52M92.24M193.34M619.65M718.54M747.7M775.46M
Basic Shares Outstanding65.03M86.14M32.73M69.52M92.24M193.34M619.65M718.54M747.7M775.46M
Dividend Payout Ratio----------

SMMT Balance Sheet

Summit Therapeutics Inc. (SMMT) balance sheet — assets, liabilities & shareholders' equity

Line itemJan'18Jan'19Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets35.84M61.29M62.11M66.42M97.31M656.71M189.71M423.75M720.3M616.6M
Cash & Short-Term Investments20.1M35.23M49.96M66.42M71.79M348.61M186.24M412.35M713.45M598.73M
Cash Only28.45M35.23M49.96M66.42M71.79M348.61M71.42M104.86M225.27M106.52M
Short-Term Investments000000114.82M307.49M488.18M492.22M
Accounts Receivable9.33M7.95M318.12K10.19M8.63M6.12M848K557K00
Days Sales Outstanding240.3750.8183.724.32K1.74K3.17K----
Inventory000-11.71M000000
Days Inventory Outstanding----------
Other Current Assets-87.49K8.37M4.98M1.52M9.73M300.49M181K10.84M6.85M17.87M
Total Non-Current Assets25.58M17.09M13.34M36.08M16.06M7.46M13.24M11.81M30.88M31.26M
Property, Plant & Equipment1.15M807.92K1.2M1.28M3.48M5.08M6.06M7.4M21.68M21.06M
Fixed Asset Turnover12.37x70.66x0.52x0.67x0.52x0.14x---0.00x
Goodwill3.51M2.38M1.15M2.03M2.01M1.8M1.89M1.86M2M1.97M
Intangible Assets20.93M13.91M7.71M11.52M10.4M00000
Long-Term Investments0000000000
Other Non-Current Assets003.27M21.26M170K577K5.28M2.55M7.21M28.99M
Total Assets
76.38M▲ 0%
78.39M▲ 2.6%
75.46M▼ 3.7%
102.5M▲ 35.8%
113.37M▲ 10.6%
664.17M▲ 485.8%
202.95M▼ 69.4%
435.56M▲ 114.6%
751.18M▲ 72.5%
647.86M▲ 0%
Asset Turnover0.19x0.73x0.01x0.01x0.02x0.00x---0.00x
Asset Growth %62.58%2.63%-3.74%35.84%10.61%485.82%-69.44%114.62%72.46%88.09%
Total Current Liabilities22.98M16.88M9.9M19.89M25.62M38.78M20.41M41.73M72.99M83.27M
Accounts Payable12.49M5.8M3.38M6.14M4.37M355K2.67M4.64M20.29M27.55M
Days Payables Outstanding46.68K84.95K7.93K--51.54474.86112.76-229.53K
Short-Term Debt00632.64K0284.24K19.77M0003.18M
Deferred Revenue (Current)13.89M01.17M8.37M7.94M00000
Other Current Liabilities-60.29K10.62M32.33K1.71M641.22K6.3M9.5M33.33M17.21M52.54M
Current Ratio1.56x3.63x6.27x3.34x3.80x16.93x9.30x10.15x9.87x9.87x
Quick Ratio1.56x3.63x6.27x3.93x3.80x16.93x9.30x10.15x9.87x9.87x
Cash Conversion Cycle----------
Total Non-Current Liabilities35.59M6.56M4.44M3.15M4.47M498.73M104.85M5.08M19.33M18.66M
Long-Term Debt00000494.54M100M0016.86M
Capital Lease Obligations962K0330.21K75K1.69M2.76M3.29M3.45M17.5M22.64M
Deferred Tax Liabilities3.37M2.2M1.61M0000000
Other Non-Current Liabilities5.73M3.28M2.12M2.51M2.78M1.43M1.56M1.63M1.83M7.3M
Total Liabilities62.4M22.59M14.34M23.05M30.09M537.51M125.26M46.81M92.32M101.92M
Total Debt00674.12K465K2.78M518.76M106.1M7.22M20.89M20.04M
Net Debt-28.45M-35.23M-49.26M-65.95M-69.01M170.16M34.67M-97.64M-204.38M-86.48M
Debt / Equity--0.01x0.01x0.03x4.10x1.37x0.02x0.03x0.03x
Debt / EBITDA----------0.02x
Net Debt / EBITDA--4.80x-------0.08x
Interest Coverage-15.65x-695.65x-206.49x-314.45x-18.02x-4.23x-26.48x--
Total Equity
13.98M▲ 0%
55.8M▲ 299.2%
61.12M▲ 9.5%
79.45M▲ 30.0%
83.28M▲ 4.8%
126.65M▲ 52.1%
77.69M▼ 38.7%
388.75M▲ 400.4%
658.86M▲ 69.5%
545.93M▲ 0%
Equity Growth %420.14%299.18%9.53%30.01%4.82%52.07%-38.66%400.37%69.48%104.93%
Book Value per Share0.210.651.861.140.900.660.130.540.880.70
Total Shareholders' Equity9.88M55.8M61.12M79.45M83.28M126.65M77.69M388.75M658.86M545.93M
Common Stock736K2.1M507.29K826K980K2.11M7.02M7.38M7.75M7.76M
Retained Earnings-132.95M-99.8M-119.46M-214.74M-299.55M-378.33M-993.26M-1.21B-2.29B-2.48B
Treasury Stock0000000000
Accumulated OCI23.91M0-3.6M-3.79M-2.2M-1.89M-2.45M-2.29M-2.54M-2.63M
Minority Interest0000000000

SMMT Cash Flow Statement

Summit Therapeutics Inc. (SMMT) cash flow — operating, investing & free cash flow history

Line itemJan'18Jan'19Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations-20.79M-35.14M-26.66M-48.11M-72.59M-41.58M-76.76M-142.11M-322.93M-322.93M
Operating CF Margin %-146.75%-61.56%-4218.72%-5594.3%-4012.55%-5904.06%----
Operating CF Growth %-237.01%-69.02%24.13%-80.44%-50.87%42.71%-84.6%-85.13%-127.25%-520.61%
Net Income-15.42M6.6M-23.88M-52.7M-88.6M-78.78M-614.93M-221.31M-1.08B-1.21B
Depreciation & Amortization348.2K1.49M1.39M2M2.46M2.51M2.05M89K-6.86M-8.09M
Stock-Based Compensation2.27M6.22M542.05K1.29M12.8M12.15M14.11M50.98M732.42M794.12M
Deferred Taxes00309.13K583K326K00000
Other Non-Cash Items3.47M1.73M-5.98M89.61K497K13.92M524.38M12.66M7.78M662.42K
Working Capital Changes-11.47M-51.18M955.98K619K-67K8.62M-2.37M15.48M23.32M35.36M
Change in Receivables-8.95M04.63M212K-1.14M975K4.53M535K00
Change in Inventory000-6.61M3.6M00000
Change in Payables00-997.71K1.64M-1.71M-4.13M2.26M2.02M11.36M21.97M
Cash from Investing-7.42M-410.52K-265.33K-421K-306K-624K-587.77M-205.34M-174.31M-334.66M
Capital Expenditures-678.01K-163.94K-265.33K-421K-306K-624K-128K-139K-657K-480K
CapEx % of Revenue4.79%0.29%41.98%48.95%16.92%88.6%----
Acquisitions-6.76M-251.82K00000000
Investments----------
Other Investing16.98K5.25K0000-474.79M-15.01M01
Cash from Financing12.77M43.85M33.11M50.55M77.92M620.24M86.51M381.23M617.53M613.65M
Debt Issued (Net)-128K-368.55K000520M-24.69M-100M00
Equity Issued (Net)21.13M46.08M37.82M50M75M100.4M5M477.89M458.31M466.36M
Dividends Paid0000000000
Share Repurchases0000000000
Other Financing-8.24M-1.86M-4.71M551K2.92M-155K106.2M3.33M159.22M147.29M
Net Change in Cash
-11.27M▲ 0%
8.86M▲ 178.6%
6.76M▼ 23.8%
2.58M▼ 61.9%
5.37M▲ 108.7%
576.82M▲ 10633.5%
-577.18M▼ 200.1%
33.76M▲ 105.8%
120.39M▲ 256.6%
-105.01M▲ 0%
Free Cash Flow
-21.47M▲ 0%
-35.31M▼ 64.5%
-15.83M▲ 55.2%
-48.53M▼ 206.6%
-72.89M▼ 50.2%
-42.21M▲ 42.1%
-76.89M▼ 82.2%
-142.25M▼ 85.0%
-323.59M▼ 127.5%
-384.53M▲ 0%
FCF Margin %-151.54%-61.85%-2504.72%-5643.26%-4029.46%-5992.66%----
FCF Growth %-242.51%-64.45%55.16%-206.58%-50.2%42.1%-82.17%-85%-127.49%-121.58%
FCF per Share-0.33-0.41-0.48-0.70-0.79-0.22-0.12-0.20-0.43-0.43
FCF Conversion (FCF/Net Income)0.73x-3.23x1.12x0.91x0.82x0.53x0.12x0.64x0.30x0.32x
Interest Paid000062.85K010.65M000
Taxes Paid00007K052K000

SMMT Key Ratios

Summit Therapeutics Inc. (SMMT) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)-593.72%31.15%-40.86%-74.98%-108.89%-75.05%-601.85%-94.9%-206.1%-291.24%
Return on Invested Capital (ROIC)-132.64%-198%-424.31%-465.43%-38.24%-32.9%-78.56%-220.17%-220.17%
Gross Margin100%98.77%96.81%100%100%-256.99%----
Net Margin-201.39%19.04%-3779.01%-6127.56%-4897.84%-11185.94%----
Debt / Equity--0.01x0.01x0.03x4.10x1.37x0.02x0.03x0.03x
Interest Coverage-15.65x-695.65x-206.49x-314.45x-18.02x-4.23x-26.48x--
FCF Conversion0.73x-3.23x1.12x0.91x0.82x0.53x0.12x0.64x0.30x0.32x
Revenue Growth391.94%302.94%-98.89%36.07%110.35%-61.07%-100%---

SMMT SEC Filings & Documents

Summit Therapeutics Inc. (SMMT) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 30, 2026·SEC

Material company update

Feb 23, 2026·SEC

Material company update

Jan 29, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 23, 2026·SEC

FY 2025

Feb 24, 2025·SEC

FY 2024

Feb 20, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Apr 30, 2026·SEC

FY 2025

Aug 11, 2025·SEC

FY 2025

May 1, 2025·SEC

SMMT Frequently Asked Questions

Summit Therapeutics Inc. (SMMT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Summit Therapeutics Inc. (SMMT) grew revenue by 0.0% over the past year. Growth has been modest.

Summit Therapeutics Inc. (SMMT) reported a net loss of $1.21B for fiscal year 2025.

Dividend & Returns

Summit Therapeutics Inc. (SMMT) has a return on equity (ROE) of -206.1%. Negative ROE indicates the company is unprofitable.

Summit Therapeutics Inc. (SMMT) had negative free cash flow of $384.5M in fiscal year 2025, likely due to heavy capital investments.

Explore More SMMT

Summit Therapeutics Inc. (SMMT) financial analysis — history, returns, DCA and operating performance tools

Full SMMT Stock Analysis

Analyst verdict, bull/bear case, risk factors and peer comparison

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Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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