23 years of historical data (2003–2025) · Healthcare · Biotechnology
Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
Summit Therapeutics Inc. currently has a negative P/E ratio, indicating the company is operating at a loss on a trailing-twelve-month basis.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $13.3B | $13.1B | $12.8B | $1.6B | $822M | $248M | $327M | $53M | $115M | $898M | $644M |
| Enterprise Value | $13.1B | $12.9B | $12.7B | $1.7B | $992M | $179M | $261M | $3M | $79M | $870M | $609M |
| P/E Ratio → | -11.91 | — | — | — | — | — | — | — | 12.09 | — | — |
| P/S Ratio | — | — | — | — | 1166.67 | 137.16 | 379.96 | 83.11 | 2.01 | 63.41 | 223.76 |
| P/B Ratio | 19.46 | 19.85 | 32.99 | 20.82 | 6.49 | 2.98 | 4.11 | 0.86 | 2.05 | 64.27 | — |
| P/FCF | — | — | — | — | — | — | — | — | — | — | 42.77 |
| P/OCF | — | — | — | — | — | — | — | — | — | — | 42.46 |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | — | — | — | 1408.27 | 99.01 | 303.27 | 5.16 | 1.39 | 61.40 | 211.58 |
| EV / EBITDA | — | — | — | — | — | — | — | — | 10.81 | — | — |
| EV / EBIT | — | — | — | — | — | — | — | — | 8.18 | — | — |
| EV / FCF | — | — | — | — | — | — | — | — | — | — | 40.45 |
Margins and return-on-capital ratios measuring operating efficiency
A negative ROE of -206.1% indicates the company is currently destroying shareholder equity.
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | — | — | — | — | -257.0% | 100.0% | 100.0% | 96.8% | 98.8% | 100.0% | 100.0% |
| Operating Margin | — | — | — | — | -11259.8% | -4764.3% | -8330.9% | -6766.4% | 9.4% | -182.3% | -1078.6% |
| Net Profit Margin | — | — | — | — | -11185.9% | -4897.8% | -6127.6% | -3779.0% | 19.0% | -201.4% | -788.8% |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -206.1% | -206.1% | -94.9% | -601.8% | -75.1% | -108.9% | -75.0% | -40.9% | 31.2% | -593.7% | -176.6% |
| ROA | -181.9% | -181.9% | -69.3% | -141.8% | -20.3% | -82.1% | -59.2% | -31.0% | 14.0% | -46.3% | -54.9% |
| ROIC | -220.2% | -220.2% | -78.6% | -32.9% | -38.2% | -465.4% | -424.3% | -198.0% | 132.6% | — | — |
| ROCE | -204.2% | -204.2% | -73.3% | -22.2% | -22.2% | -101.2% | -96.7% | -67.3% | 9.4% | -57.7% | -92.4% |
Solvency and debt-coverage ratios — lower is generally safer
The company holds a net cash position — cash of $225M exceeds total debt of $21M, providing substantial financial flexibility for buybacks, acquisitions, or weathering downturns.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.03 | 0.03 | 0.02 | 1.37 | 4.10 | 0.03 | 0.01 | 0.01 | — | — | — |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| Net Debt / Equity | — | -0.31 | -0.25 | 0.45 | 1.34 | -0.83 | -0.83 | -0.81 | -0.63 | -2.04 | — |
| Net Debt / EBITDA | — | — | — | — | — | — | — | — | -4.80 | — | — |
| Debt / FCF | — | — | — | — | — | — | — | — | — | — | -2.33 |
| Interest Coverage | — | — | -26.48 | -4.23 | -18.02 | -314.45 | -206.49 | -695.65 | 15.65 | — | -28.83 |
Net cash position: cash ($225M) exceeds total debt ($21M)
Short-term solvency ratios and asset-utilisation metrics
Summit Therapeutics Inc.'s current ratio of 9.87x is well above the 1.0 safety threshold, indicating strong short-term liquidity with ample room to cover current liabilities. The current ratio has improved from 9.30x to 9.87x over the past 3 years.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 9.87 | 9.87 | 10.15 | 9.30 | 16.93 | 3.80 | 3.34 | 6.27 | 3.63 | 1.56 | 3.06 |
| Quick Ratio | 9.87 | 9.87 | 10.15 | 9.30 | 16.93 | 3.80 | 3.93 | 6.27 | 3.63 | 1.56 | 3.06 |
| Cash Ratio | 9.77 | 9.77 | 9.88 | 9.13 | 8.99 | 2.80 | 3.34 | 5.05 | 2.09 | 1.24 | 3.22 |
| Asset Turnover | — | — | — | — | 0.00 | 0.02 | 0.01 | 0.01 | 0.73 | 0.19 | 0.06 |
| Inventory Turnover | — | — | — | — | — | — | — | — | — | — | — |
| Days Sales Outstanding | — | — | — | — | 3169.09 | 1740.26 | 4323.55 | 183.72 | 50.80 | 240.37 | 583.63 |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Summit Therapeutics Inc. does not currently pay a dividend and has no material buyback yield, reinvesting earnings back into the business.
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | — | — | — | — | 8.3% | — | — |
| FCF Yield | — | — | — | — | — | — | — | — | — | — | 2.3% |
| Buyback Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Shares Outstanding | — | $748M | $719M | $620M | $193M | $92M | $70M | $33M | $86M | $65M | $62M |
Compare SMMT with 10 similar companies in its peer group
| Company | Market Cap | P/E | EV/EBITDA | P/FCF | Gross Margin | Op Margin | ROE | ROIC | Debt/EBITDA |
|---|---|---|---|---|---|---|---|---|---|
| $13B | -11.9 | — | — | — | — | -206.1% | -220.2% | — | |
| $7B | -22.9 | — | — | 100.0% | -891.3% | -25.8% | -24.9% | — | |
| $30B | -24.0 | — | — | — | — | -58.1% | -54.3% | — | |
| $3B | -27.0 | — | — | 96.3% | -178.4% | -37.2% | -38.5% | — | |
| $8B | -17.5 | — | — | — | — | -36.7% | -32.5% | — | |
| $9B | 43.4 | 49.2 | 46.3 | 92.6% | 41.5% | 18.9% | 18.0% | 0.1 | |
| $12B | 16.6 | 12.7 | 13.9 | 96.4% | 37.6% | 35.5% | 32.1% | 0.2 | |
| $186M | -2.5 | — | — | — | -48.7% | -86.9% | -1879.3% | — | |
| $6B | -10.0 | — | — | — | — | -62.5% | — | — | |
| $2B | -7.5 | — | — | 96.0% | -156.3% | -63.3% | -64.1% | — | |
| $132M | -1102.9 | — | — | 90.3% | -18.0% | — | — | — | |
| Healthcare Median | — | 22.3 | 14.4 | 18.5 | 63.9% | -5.2% | -33.7% | -11.2% | 3.3 |
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Summit Therapeutics Inc.'s current P/E ratio is -11.9x. The historical average is 12.1x.
Summit Therapeutics Inc.'s return on equity (ROE) is -206.1%. The historical average is -76.9%.
Based on historical data, Summit Therapeutics Inc. is trading at a P/E of -11.9x. Compare with industry peers and growth rates for a complete picture.