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ABSI vs RXRX vs SDGR

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ABSI
Absci Corporation

Biotechnology

HealthcareNASDAQ • US
Market Cap$925M
5Y Perf.-79.1%
RXRX
Recursion Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.53B
5Y Perf.-88.7%
SDGR
Schrödinger, Inc.

Medical - Healthcare Information Services

HealthcareNASDAQ • US
Market Cap$970M
5Y Perf.-80.8%

ABSI vs RXRX vs SDGR — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ABSI logoABSI
RXRX logoRXRX
SDGR logoSDGR
IndustryBiotechnologyBiotechnologyMedical - Healthcare Information Services
Market Cap$925M$1.53B$970M
Revenue (TTM)$3M$66M$255M
Net Income (TTM)$-115M$-560M$-103M
Gross Margin-13.2%-34.4%55.3%
Operating Margin-44.8%-8.8%-64.7%
Total Debt$5M$78M$109M
Cash & Equiv.$20M$743M$231M

ABSI vs RXRX vs SDGRLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ABSI
RXRX
SDGR
StockJul 21May 26Return
Absci Corporation (ABSI)10020.9-79.1%
Recursion Pharmaceu… (RXRX)10011.3-88.7%
Schrödinger, Inc. (SDGR)10019.2-80.8%

Price return only. Dividends and distributions are not included.

Quick Verdict: ABSI vs RXRX vs SDGR

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: SDGR leads in 3 of 6 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Absci Corporation is the stronger pick specifically for recent price momentum and sentiment. As sector peers, any of these can serve as alternatives in the same allocation.
ABSI
Absci Corporation
The Defensive Pick

ABSI is the clearest fit if your priority is sleep-well-at-night and defensive.

  • Lower volatility, beta 2.82, Low D/E 2.8%, current ratio 6.57x
  • Beta 2.82, current ratio 6.57x
  • +124.5% vs SDGR's -44.9%
Best for: sleep-well-at-night and defensive
RXRX
Recursion Pharmaceuticals, Inc.
The Growth Play

RXRX is the clearest fit if your priority is growth exposure.

  • Rev growth 26.9%, EPS growth 14.8%, 3Y rev CAGR 23.5%
  • 26.9% revenue growth vs ABSI's -38.2%
Best for: growth exposure
SDGR
Schrödinger, Inc.
The Income Pick

SDGR carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • beta 1.72
  • -54.7% 10Y total return vs ABSI's -72.4%
  • -40.6% margin vs ABSI's -41.1%
Best for: income & stability and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthRXRX logoRXRX26.9% revenue growth vs ABSI's -38.2%
Quality / MarginsSDGR logoSDGR-40.6% margin vs ABSI's -41.1%
Stability / SafetySDGR logoSDGRBeta 1.72 vs RXRX's 3.18
DividendsTieNone of these 3 stocks pay a meaningful dividend
Momentum (1Y)ABSI logoABSI+124.5% vs SDGR's -44.9%
Efficiency (ROA)SDGR logoSDGR-15.3% ROA vs ABSI's -51.0%, ROIC -39.4% vs -58.0%

ABSI vs RXRX vs SDGR — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ABSIAbsci Corporation

Segment breakdown not available.

RXRXRecursion Pharmaceuticals, Inc.
FY 2025
License and Service
99.4%$74M
Grant
0.6%$425,000
SDGRSchrödinger, Inc.
FY 2025
Software Products And Services
34.2%$200M
Revenue From Contract With Customer Before Software Contribution
31.5%$184M
On Premise Software
17.4%$101M
Hosted Software
7.7%$45M
Maintenance
4.7%$27M
Software Contribution
2.7%$16M
Professional Services
1.7%$10M

ABSI vs RXRX vs SDGR — Financial Metrics

Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLSDGRLAGGINGRXRX

Income & Cash Flow (Last 12 Months)

SDGR leads this category, winning 5 of 6 comparable metrics.

SDGR is the larger business by revenue, generating $255M annually — 91.0x ABSI's $3M. Profitability is closely matched — net margins range from -40.6% (SDGR) to -41.1% (ABSI). On growth, SDGR holds the edge at -1.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricABSI logoABSIAbsci CorporationRXRX logoRXRXRecursion Pharmac…SDGR logoSDGRSchrödinger, Inc.
RevenueTrailing 12 months$3M$66M$255M
EBITDAEarnings before interest/tax-$114M-$521M-$159M
Net IncomeAfter-tax profit-$115M-$560M-$103M
Free Cash FlowCash after capex-$94M-$326M-$148M
Gross MarginGross profit ÷ Revenue-13.2%-34.4%+55.3%
Operating MarginEBIT ÷ Revenue-44.8%-8.8%-64.7%
Net MarginNet income ÷ Revenue-41.1%-8.4%-40.6%
FCF MarginFCF ÷ Revenue-33.6%-4.9%-58.2%
Rev. Growth (YoY)Latest quarter vs prior year-2.3%-56.1%-1.6%
EPS Growth (YoY)Latest quarter vs prior year+20.0%+56.0%+1.2%
SDGR leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

SDGR leads this category, winning 2 of 3 comparable metrics.
MetricABSI logoABSIAbsci CorporationRXRX logoRXRXRecursion Pharmac…SDGR logoSDGRSchrödinger, Inc.
Market CapShares × price$925M$1.5B$970M
Enterprise ValueMkt cap + debt − cash$910M$869M$849M
Trailing P/EPrice ÷ TTM EPS-7.08x-2.38x-9.21x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue330.32x20.54x3.79x
Price / BookPrice ÷ Book value/share4.30x1.36x2.62x
Price / FCFMarket cap ÷ FCF77.86x
SDGR leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

SDGR leads this category, winning 4 of 8 comparable metrics.

SDGR delivers a -30.8% return on equity — every $100 of shareholder capital generates $-31 in annual profit, vs $-60 for ABSI. ABSI carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to SDGR's 0.30x.

MetricABSI logoABSIAbsci CorporationRXRX logoRXRXRecursion Pharmac…SDGR logoSDGRSchrödinger, Inc.
ROE (TTM)Return on equity-59.7%-54.3%-30.8%
ROA (TTM)Return on assets-51.0%-40.6%-15.3%
ROICReturn on invested capital-58.0%-95.8%-39.4%
ROCEReturn on capital employed-65.9%-50.1%-28.6%
Piotroski ScoreFundamental quality 0–9444
Debt / EquityFinancial leverage0.03x0.07x0.30x
Net DebtTotal debt minus cash-$15M-$665M-$121M
Cash & Equiv.Liquid assets$20M$743M$231M
Total DebtShort + long-term debt$5M$78M$109M
Interest CoverageEBIT ÷ Interest expense-592.44x-336.46x
SDGR leads this category, winning 4 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

ABSI leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in ABSI five years ago would be worth $2,756 today (with dividends reinvested), compared to $1,225 for RXRX. Over the past 12 months, ABSI leads with a +124.5% total return vs SDGR's -44.9%. The 3-year compound annual growth rate (CAGR) favors ABSI at 61.2% vs SDGR's -22.4% — a key indicator of consistent wealth creation.

MetricABSI logoABSIAbsci CorporationRXRX logoRXRXRecursion Pharmac…SDGR logoSDGRSchrödinger, Inc.
YTD ReturnYear-to-date+64.8%-18.3%-27.8%
1-Year ReturnPast 12 months+124.5%-17.5%-44.9%
3-Year ReturnCumulative with dividends+319.0%-38.7%-53.2%
5-Year ReturnCumulative with dividends-72.4%-87.8%-80.7%
10-Year ReturnCumulative with dividends-72.4%-80.9%-54.7%
CAGR (3Y)Annualised 3-year return+61.2%-15.1%-22.4%
ABSI leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ABSI and SDGR each lead in 1 of 2 comparable metrics.

SDGR is the less volatile stock with a 1.72 beta — it tends to amplify market swings less than RXRX's 3.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ABSI currently trades 95.4% from its 52-week high vs SDGR's 47.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricABSI logoABSIAbsci CorporationRXRX logoRXRXRecursion Pharmac…SDGR logoSDGRSchrödinger, Inc.
Beta (5Y)Sensitivity to S&P 5002.82x3.18x1.72x
52-Week HighHighest price in past year$6.24$7.18$27.63
52-Week LowLowest price in past year$2.24$2.80$10.95
% of 52W HighCurrent price vs 52-week peak+95.4%+47.8%+47.0%
RSI (14)Momentum oscillator 0–10081.447.458.8
Avg Volume (50D)Average daily shares traded4.3M13.2M1.3M
Evenly matched — ABSI and SDGR each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: ABSI as "Buy", RXRX as "Hold", SDGR as "Buy". Consensus price targets imply 220.7% upside for RXRX (target: $11) vs 3.5% for ABSI (target: $6).

MetricABSI logoABSIAbsci CorporationRXRX logoRXRXRecursion Pharmac…SDGR logoSDGRSchrödinger, Inc.
Analyst RatingConsensus buy/hold/sellBuyHoldBuy
Price TargetConsensus 12-month target$6.16$11.00$18.00
# AnalystsCovering analysts121012
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

SDGR leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). ABSI leads in 1 (Total Returns). 1 tied.

Best OverallSchrödinger, Inc. (SDGR)Leads 3 of 6 categories
Loading custom metrics...

ABSI vs RXRX vs SDGR: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is ABSI or RXRX or SDGR a better buy right now?

For growth investors, Recursion Pharmaceuticals, Inc.

(RXRX) is the stronger pick with 26. 9% revenue growth year-over-year, versus -38. 2% for Absci Corporation (ABSI). Analysts rate Absci Corporation (ABSI) a "Buy" — based on 12 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — ABSI or RXRX or SDGR?

Over the past 5 years, Absci Corporation (ABSI) delivered a total return of -72.

4%, compared to -87. 8% for Recursion Pharmaceuticals, Inc. (RXRX). Over 10 years, the gap is even starker: SDGR returned -54. 7% versus RXRX's -80. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — ABSI or RXRX or SDGR?

By beta (market sensitivity over 5 years), Schrödinger, Inc.

(SDGR) is the lower-risk stock at 1. 72β versus Recursion Pharmaceuticals, Inc. 's 3. 18β — meaning RXRX is approximately 84% more volatile than SDGR relative to the S&P 500. On balance sheet safety, Absci Corporation (ABSI) carries a lower debt/equity ratio of 3% versus 30% for Schrödinger, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — ABSI or RXRX or SDGR?

By revenue growth (latest reported year), Recursion Pharmaceuticals, Inc.

(RXRX) is pulling ahead at 26. 9% versus -38. 2% for Absci Corporation (ABSI). On earnings-per-share growth, the picture is similar: Schrödinger, Inc. grew EPS 45. 1% year-over-year, compared to 10. 6% for Absci Corporation. Over a 3-year CAGR, RXRX leads at 23. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — ABSI or RXRX or SDGR?

Schrödinger, Inc.

(SDGR) is the more profitable company, earning -40. 4% net margin versus -41. 1% for Absci Corporation — meaning it keeps -40. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: SDGR leads at -65. 2% versus -44. 5% for ABSI. At the gross margin level — before operating expenses — SDGR leads at 55. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — ABSI or RXRX or SDGR?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is ABSI or RXRX or SDGR better for a retirement portfolio?

For long-horizon retirement investors, Schrödinger, Inc.

(SDGR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Recursion Pharmaceuticals, Inc. (RXRX) carries a higher beta of 3. 18 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SDGR: -54. 7%, RXRX: -80. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between ABSI and RXRX and SDGR?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ABSI is a small-cap quality compounder stock; RXRX is a small-cap high-growth stock; SDGR is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
  • Gross Margin > 33%
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