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Stock Comparison

IRWD vs CPIX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
IRWD
Ironwood Pharmaceuticals, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$788M
5Y Perf.-50.4%
CPIX
Cumberland Pharmaceuticals Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$65M
5Y Perf.+32.0%

IRWD vs CPIX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
IRWD logoIRWD
CPIX logoCPIX
IndustryDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & Generic
Market Cap$788M$65M
Revenue (TTM)$296M$42M
Net Income (TTM)$24M$-7M
Gross Margin90.6%82.9%
Operating Margin33.2%-17.2%
Forward P/E3.6x
Total Debt$598M$10M
Cash & Equiv.$215M$11M

IRWD vs CPIXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

IRWD
CPIX
StockMay 20May 26Return
Ironwood Pharmaceut… (IRWD)10049.6-50.4%
Cumberland Pharmace… (CPIX)100132.0+32.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: IRWD vs CPIX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: IRWD leads in 4 of 7 categories, making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Cumberland Pharmaceuticals Inc. is the stronger pick specifically for growth and revenue expansion and capital preservation and lower volatility. As sector peers, any of these can serve as alternatives in the same allocation.
IRWD
Ironwood Pharmaceuticals, Inc.
The Value Play

IRWD carries the broadest edge in this set and is the clearest fit for value and quality.

  • Better valuation composite
  • 8.1% margin vs CPIX's -17.6%
  • +421.1% vs CPIX's -0.9%
Best for: value and quality
CPIX
Cumberland Pharmaceuticals Inc.
The Income Pick

CPIX is the clearest fit if your priority is income & stability and growth exposure.

  • beta 1.09
  • Rev growth 17.6%, EPS growth 58.7%, 3Y rev CAGR 2.0%
  • -7.0% 10Y total return vs IRWD's -51.8%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthCPIX logoCPIX17.6% revenue growth vs IRWD's -15.7%
ValueIRWD logoIRWDBetter valuation composite
Quality / MarginsIRWD logoIRWD8.1% margin vs CPIX's -17.6%
Stability / SafetyCPIX logoCPIXBeta 1.09 vs IRWD's 2.50
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)IRWD logoIRWD+421.1% vs CPIX's -0.9%
Efficiency (ROA)IRWD logoIRWD6.6% ROA vs CPIX's -10.5%, ROIC 54.0% vs -8.6%

IRWD vs CPIX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

IRWDIronwood Pharmaceuticals, Inc.
FY 2025
Collaborative Arrangements
99.3%$296M
Collaborative arrangement, collaboration and license agreements
0.6%$2M
Royalty
0.1%$300,000
Collaborative arrangement, other agreements
0.0%$87,000
CPIXCumberland Pharmaceuticals Inc.
FY 2025
Product
74.8%$40M
Product - Vibativ
17.6%$9M
Product - Other
7.6%$4M

IRWD vs CPIX — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLIRWDLAGGINGCPIX

Income & Cash Flow (Last 12 Months)

IRWD leads this category, winning 5 of 6 comparable metrics.

IRWD is the larger business by revenue, generating $296M annually — 7.1x CPIX's $42M. IRWD is the more profitable business, keeping 8.1% of every revenue dollar as net income compared to CPIX's -17.6%. On growth, CPIX holds the edge at -22.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricIRWD logoIRWDIronwood Pharmace…CPIX logoCPIXCumberland Pharma…
RevenueTrailing 12 months$296M$42M
EBITDAEarnings before interest/tax$100M-$4M
Net IncomeAfter-tax profit$24M-$7M
Free Cash FlowCash after capex$127M$1M
Gross MarginGross profit ÷ Revenue+90.6%+82.9%
Operating MarginEBIT ÷ Revenue+33.2%-17.2%
Net MarginNet income ÷ Revenue+8.1%-17.6%
FCF MarginFCF ÷ Revenue+42.9%+3.2%
Rev. Growth (YoY)Latest quarter vs prior year-47.3%-22.0%
EPS Growth (YoY)Latest quarter vs prior year-190.8%-3.8%
IRWD leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

Evenly matched — IRWD and CPIX each lead in 2 of 4 comparable metrics.

On an enterprise value basis, IRWD's 9.7x EV/EBITDA is more attractive than CPIX's 25.7x.

MetricIRWD logoIRWDIronwood Pharmace…CPIX logoCPIXCumberland Pharma…
Market CapShares × price$788M$65M
Enterprise ValueMkt cap + debt − cash$1.2B$64M
Trailing P/EPrice ÷ TTM EPS32.20x-23.00x
Forward P/EPrice ÷ next-FY EPS est.3.64x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple9.70x25.70x
Price / SalesMarket cap ÷ Revenue2.66x1.47x
Price / BookPrice ÷ Book value/share2.66x
Price / FCFMarket cap ÷ FCF6.20x13.52x
Evenly matched — IRWD and CPIX each lead in 2 of 4 comparable metrics.

Profitability & Efficiency

IRWD leads this category, winning 4 of 6 comparable metrics.
MetricIRWD logoIRWDIronwood Pharmace…CPIX logoCPIXCumberland Pharma…
ROE (TTM)Return on equity-29.7%
ROA (TTM)Return on assets+6.6%-10.5%
ROICReturn on invested capital+54.0%-8.6%
ROCEReturn on capital employed+50.9%-6.6%
Piotroski ScoreFundamental quality 0–966
Debt / EquityFinancial leverage0.41x
Net DebtTotal debt minus cash$382M-$1M
Cash & Equiv.Liquid assets$215M$11M
Total DebtShort + long-term debt$598M$10M
Interest CoverageEBIT ÷ Interest expense3.68x-15.15x
IRWD leads this category, winning 4 of 6 comparable metrics.

Total Returns (Dividends Reinvested)

CPIX leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in CPIX five years ago would be worth $16,185 today (with dividends reinvested), compared to $4,604 for IRWD. Over the past 12 months, IRWD leads with a +421.1% total return vs CPIX's -0.9%. The 3-year compound annual growth rate (CAGR) favors CPIX at 37.5% vs IRWD's -22.8% — a key indicator of consistent wealth creation.

MetricIRWD logoIRWDIronwood Pharmace…CPIX logoCPIXCumberland Pharma…
YTD ReturnYear-to-date+13.1%+9.8%
1-Year ReturnPast 12 months+421.1%-0.9%
3-Year ReturnCumulative with dividends-54.0%+160.1%
5-Year ReturnCumulative with dividends-54.0%+61.9%
10-Year ReturnCumulative with dividends-51.8%-7.0%
CAGR (3Y)Annualised 3-year return-22.8%+37.5%
CPIX leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — IRWD and CPIX each lead in 1 of 2 comparable metrics.

CPIX is the less volatile stock with a 1.09 beta — it tends to amplify market swings less than IRWD's 2.50 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IRWD currently trades 83.6% from its 52-week high vs CPIX's 69.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricIRWD logoIRWDIronwood Pharmace…CPIX logoCPIXCumberland Pharma…
Beta (5Y)Sensitivity to S&P 5002.50x1.09x
52-Week HighHighest price in past year$5.78$6.27
52-Week LowLowest price in past year$0.53$1.85
% of 52W HighCurrent price vs 52-week peak+83.6%+69.7%
RSI (14)Momentum oscillator 0–10065.975.5
Avg Volume (50D)Average daily shares traded2.7M1.2M
Evenly matched — IRWD and CPIX each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.
MetricIRWD logoIRWDIronwood Pharmace…CPIX logoCPIXCumberland Pharma…
Analyst RatingConsensus buy/hold/sellHold
Price TargetConsensus 12-month target$4.80
# AnalystsCovering analysts30
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.4%
Insufficient data to determine a leader in this category.
Key Takeaway

IRWD leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). CPIX leads in 1 (Total Returns). 2 tied.

Best OverallIronwood Pharmaceuticals, I… (IRWD)Leads 2 of 6 categories
Loading custom metrics...

IRWD vs CPIX: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is IRWD or CPIX a better buy right now?

For growth investors, Cumberland Pharmaceuticals Inc.

(CPIX) is the stronger pick with 17. 6% revenue growth year-over-year, versus -15. 7% for Ironwood Pharmaceuticals, Inc. (IRWD). Ironwood Pharmaceuticals, Inc. (IRWD) offers the better valuation at 32. 2x trailing P/E (3. 6x forward), making it the more compelling value choice. Analysts rate Ironwood Pharmaceuticals, Inc. (IRWD) a "Hold" — based on 30 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — IRWD or CPIX?

Over the past 5 years, Cumberland Pharmaceuticals Inc.

(CPIX) delivered a total return of +61. 9%, compared to -54. 0% for Ironwood Pharmaceuticals, Inc. (IRWD). Over 10 years, the gap is even starker: CPIX returned -7. 0% versus IRWD's -51. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — IRWD or CPIX?

By beta (market sensitivity over 5 years), Cumberland Pharmaceuticals Inc.

(CPIX) is the lower-risk stock at 1. 09β versus Ironwood Pharmaceuticals, Inc. 's 2. 50β — meaning IRWD is approximately 129% more volatile than CPIX relative to the S&P 500.

04

Which is growing faster — IRWD or CPIX?

By revenue growth (latest reported year), Cumberland Pharmaceuticals Inc.

(CPIX) is pulling ahead at 17. 6% versus -15. 7% for Ironwood Pharmaceuticals, Inc. (IRWD). Over a 3-year CAGR, CPIX leads at 2. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — IRWD or CPIX?

Ironwood Pharmaceuticals, Inc.

(IRWD) is the more profitable company, earning 8. 1% net margin versus -6. 4% for Cumberland Pharmaceuticals Inc. — meaning it keeps 8. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IRWD leads at 40. 1% versus -6. 3% for CPIX. At the gross margin level — before operating expenses — IRWD leads at 99. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — IRWD or CPIX?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is IRWD or CPIX better for a retirement portfolio?

For long-horizon retirement investors, Cumberland Pharmaceuticals Inc.

(CPIX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 09)). Ironwood Pharmaceuticals, Inc. (IRWD) carries a higher beta of 2. 50 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CPIX: -7. 0%, IRWD: -51. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between IRWD and CPIX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: IRWD is a small-cap quality compounder stock; CPIX is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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IRWD

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  • Market Cap > $100B
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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 49%
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(IRWD: -47.3% · CPIX: -22.0%)

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