ORIC
ORIC Pharmaceuticals, Inc.
Biotechnology
Market Cap$912M
5Y Perf.-64.8%
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Stock Comparison
ORIC vs KYMR
Revenue, margins, valuation, and 5-year total return — side by side.
KYMR
Kymera Therapeutics, Inc.
Biotechnology
Market Cap$6.91B
5Y Perf.+165.3%
ORIC vs KYMR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ORIC | KYMR |
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $912M | $6.91B |
| Revenue (TTM) | $0.00 | $51M |
| Net Income (TTM) | $-135M | $-315M |
| Gross Margin | — | 33.2% |
| Operating Margin | — | -7.0% |
| Total Debt | $12M | $82M |
| Cash & Equiv. | $46M | $357M |
ORIC vs KYMR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
ORIC
KYMR
| Stock | Aug 20 | May 26 | Return |
|---|---|---|---|
| ORIC Pharmaceutical… (ORIC) | 100 | 35.2 | -64.8% |
| Kymera Therapeutics… (KYMR) | 100 | 265.3 | +165.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ORIC vs KYMR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Bottom line: ORIC and KYMR are tied at the top with 2 categories each — the right choice depends on your priorities. Kymera Therapeutics, Inc. is the stronger pick specifically for recent price momentum and sentiment and operational efficiency and capital deployment. As sector peers, any of these can serve as alternatives in the same allocation.
ORIC
ORIC Pharmaceuticals, Inc.
The Income Pick
ORIC has the current edge in this matchup, primarily because of its strength in income & stability and growth exposure.
- beta 1.12
- EPS growth 19.7%
- Lower volatility, beta 1.12, Low D/E 3.0%, current ratio 14.13x
Best for: income & stability and growth exposure
KYMR
Kymera Therapeutics, Inc.
The Long-Run Compounder
KYMR is the clearest fit if your priority is long-term compounding.
- 154.4% 10Y total return vs ORIC's -65.8%
- +190.7% vs ORIC's +87.4%
- -22.3% ROA vs ORIC's -33.3%, ROIC -24.9% vs -39.9%
Best for: long-term compounding
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | ORIC | -1.8% revenue growth vs KYMR's -16.7% |
| Stability / Safety | ORIC | Beta 1.12 vs KYMR's 1.15, lower leverage |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | KYMR | +190.7% vs ORIC's +87.4% |
| Efficiency (ROA) | KYMR | -22.3% ROA vs ORIC's -33.3%, ROIC -24.9% vs -39.9% |
ORIC vs KYMR — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
BEST OVERALLKYMRLAGGINGORIC
ORICORIC Pharmaceuticals,…
1leads
KYMRKymera Therapeutics, …
2leads
6 Total Categories
CATEGORYLEADERvs ORICMETRICS WON
Income & Cash FlowRevenue, margins, and cash flow strength
ORIC1/1
Valuation MetricsMultiples, price ratios, and targets
Tied
—
Profitability & EfficiencyROE, ROIC, leverage, and quality scores
KYMR6/8
Total Returns1Y, 3Y, 5Y total returns with dividends
KYMR6/6
Risk & VolatilityBeta, volatility, and downside exposure
Tied
—
Analyst OutlookRatings, price targets, and dividends
—
—
Income & Cash Flow (Last 12 Months)
ORIC leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
KYMR and ORIC operate at a comparable scale, with $51M and $0 in trailing revenue.
| Metric | ORICORIC Pharmaceutic… | KYMRKymera Therapeuti… |
|---|---|---|
| RevenueTrailing 12 months | $0 | $51M |
| EBITDAEarnings before interest/tax | -$149M | -$352M |
| Net IncomeAfter-tax profit | -$135M | -$315M |
| Free Cash FlowCash after capex | -$111M | -$244M |
| Gross MarginGross profit ÷ Revenue | — | +33.2% |
| Operating MarginEBIT ÷ Revenue | — | -7.0% |
| Net MarginNet income ÷ Revenue | — | -6.1% |
| FCF MarginFCF ÷ Revenue | — | -4.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +55.5% |
| EPS Growth (YoY)Latest quarter vs prior year | +19.0% | +13.4% |
ORIC leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
Evenly matched — ORIC and KYMR each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ORICORIC Pharmaceutic… | KYMRKymera Therapeuti… |
|---|---|---|
| Market CapShares × price | $912M | $6.9B |
| Enterprise ValueMkt cap + debt − cash | $878M | $6.6B |
| Trailing P/EPrice ÷ TTM EPS | -5.99x | -22.93x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 176.26x |
| Price / BookPrice ÷ Book value/share | 2.01x | 4.52x |
| Price / FCFMarket cap ÷ FCF | — | — |
Evenly matched — ORIC and KYMR each lead in 1 of 2 comparable metrics.
Profitability & Efficiency
KYMR leads this category, winning 6 of 8 comparable metrics.
Profitability & Efficiency
KYMR delivers a -25.0% return on equity — every $100 of shareholder capital generates $-25 in annual profit, vs $-35 for ORIC. ORIC carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to KYMR's 0.05x. On the Piotroski fundamental quality scale (0–9), KYMR scores 4/9 vs ORIC's 3/9, reflecting mixed financial health.
| Metric | ORICORIC Pharmaceutic… | KYMRKymera Therapeuti… |
|---|---|---|
| ROE (TTM)Return on equity | -35.3% | -25.0% |
| ROA (TTM)Return on assets | -33.3% | -22.3% |
| ROICReturn on invested capital | -39.9% | -24.9% |
| ROCEReturn on capital employed | -44.7% | -27.2% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 |
| Debt / EquityFinancial leverage | 0.03x | 0.05x |
| Net DebtTotal debt minus cash | -$34M | -$275M |
| Cash & Equiv.Liquid assets | $46M | $357M |
| Total DebtShort + long-term debt | $12M | $82M |
| Interest CoverageEBIT ÷ Interest expense | — | -2119.53x |
KYMR leads this category, winning 6 of 8 comparable metrics.
Total Returns (Dividends Reinvested)
KYMR leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in KYMR five years ago would be worth $19,212 today (with dividends reinvested), compared to $3,689 for ORIC. Over the past 12 months, KYMR leads with a +190.7% total return vs ORIC's +87.4%. The 3-year compound annual growth rate (CAGR) favors KYMR at 45.0% vs ORIC's 19.1% — a key indicator of consistent wealth creation.
| Metric | ORICORIC Pharmaceutic… | KYMRKymera Therapeuti… |
|---|---|---|
| YTD ReturnYear-to-date | +7.8% | +16.3% |
| 1-Year ReturnPast 12 months | +87.4% | +190.7% |
| 3-Year ReturnCumulative with dividends | +68.8% | +205.1% |
| 5-Year ReturnCumulative with dividends | -63.1% | +92.1% |
| 10-Year ReturnCumulative with dividends | -65.8% | +154.4% |
| CAGR (3Y)Annualised 3-year return | +19.1% | +45.0% |
KYMR leads this category, winning 6 of 6 comparable metrics.
Risk & Volatility
Evenly matched — ORIC and KYMR each lead in 1 of 2 comparable metrics.
Risk & Volatility
ORIC is the less volatile stock with a 1.12 beta — it tends to amplify market swings less than KYMR's 1.15 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KYMR currently trades 82.2% from its 52-week high vs ORIC's 59.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ORICORIC Pharmaceutic… | KYMRKymera Therapeuti… |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.12x | 1.15x |
| 52-Week HighHighest price in past year | $14.93 | $103.00 |
| 52-Week LowLowest price in past year | $4.52 | $28.06 |
| % of 52W HighCurrent price vs 52-week peak | +59.0% | +82.2% |
| RSI (14)Momentum oscillator 0–100 | 39.7 | 54.1 |
| Avg Volume (50D)Average daily shares traded | 1.9M | 602K |
Evenly matched — ORIC and KYMR each lead in 1 of 2 comparable metrics.
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates ORIC as "Buy" and KYMR as "Buy". Consensus price targets imply 146.9% upside for ORIC (target: $22) vs 38.3% for KYMR (target: $117).
| Metric | ORICORIC Pharmaceutic… | KYMRKymera Therapeuti… |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $21.75 | $117.06 |
| # AnalystsCovering analysts | 10 | 26 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
Insufficient data to determine a leader in this category.
Key Takeaway
KYMR leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). ORIC leads in 1 (Income & Cash Flow). 2 tied.
Best OverallKymera Therapeutics, Inc. (KYMR)Leads 2 of 6 categories
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ORIC vs KYMR: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is ORIC or KYMR a better buy right now?
Analysts rate ORIC Pharmaceuticals, Inc.
(ORIC) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ORIC or KYMR?
Over the past 5 years, Kymera Therapeutics, Inc.
(KYMR) delivered a total return of +92. 1%, compared to -63. 1% for ORIC Pharmaceuticals, Inc. (ORIC). Over 10 years, the gap is even starker: KYMR returned +154. 4% versus ORIC's -65. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ORIC or KYMR?
By beta (market sensitivity over 5 years), ORIC Pharmaceuticals, Inc.
(ORIC) is the lower-risk stock at 1. 12β versus Kymera Therapeutics, Inc. 's 1. 15β — meaning KYMR is approximately 3% more volatile than ORIC relative to the S&P 500. On balance sheet safety, ORIC Pharmaceuticals, Inc. (ORIC) carries a lower debt/equity ratio of 3% versus 5% for Kymera Therapeutics, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — ORIC or KYMR?
On earnings-per-share growth, the picture is similar: ORIC Pharmaceuticals, Inc.
grew EPS 19. 7% year-over-year, compared to -23. 8% for Kymera Therapeutics, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ORIC or KYMR?
ORIC Pharmaceuticals, Inc.
(ORIC) is the more profitable company, earning 0. 0% net margin versus -794. 4% for Kymera Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ORIC leads at 0. 0% versus -891. 3% for KYMR. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — ORIC or KYMR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is ORIC or KYMR better for a retirement portfolio?
For long-horizon retirement investors, Kymera Therapeutics, Inc.
(KYMR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 15), +154. 4% 10Y return). Both have compounded well over 10 years (KYMR: +154. 4%, ORIC: -65. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between ORIC and KYMR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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