Biotechnology
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RAPP vs PTCT
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
RAPP vs PTCT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $1.46B | $5.35B |
| Revenue (TTM) | $20M | $827M |
| Net Income (TTM) | $-107M | $-187M |
| Gross Margin | -1.3% | 49.7% |
| Operating Margin | -6.1% | -8.3% |
| Forward P/E | — | 8.3x |
| Total Debt | $11M | $492M |
| Cash & Equiv. | $53M | $985M |
RAPP vs PTCT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jun 24 | May 26 | Return |
|---|---|---|---|
| Rapport Therapeutic… (RAPP) | 100 | 171.7 | +71.7% |
| PTC Therapeutics, I… (PTCT) | 100 | 210.9 | +110.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: RAPP vs PTCT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
RAPP is the clearest fit if your priority is momentum.
- +290.7% vs PTCT's +58.2%
PTCT carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 1.13
- Rev growth 114.5%, EPS growth 264.5%, 3Y rev CAGR 35.3%
- 7.3% 10Y total return vs RAPP's 92.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 114.5% revenue growth vs RAPP's -20.9% | |
| Quality / Margins | -22.6% margin vs RAPP's -5.4% | |
| Stability / Safety | Beta 1.13 vs RAPP's 1.55 | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +290.7% vs PTCT's +58.2% | |
| Efficiency (ROA) | -6.8% ROA vs RAPP's -23.4% |
RAPP vs PTCT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
RAPP vs PTCT — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
PTCT leads this category, winning 4 of 5 comparable metrics.
Income & Cash Flow (Last 12 Months)
PTCT is the larger business by revenue, generating $827M annually — 41.4x RAPP's $20M. Profitability is closely matched — net margins range from -22.6% (PTCT) to -5.4% (RAPP).
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $20M | $827M |
| EBITDAEarnings before interest/tax | -$121M | -$37M |
| Net IncomeAfter-tax profit | -$107M | -$187M |
| Free Cash FlowCash after capex | -$80M | -$229M |
| Gross MarginGross profit ÷ Revenue | -1.3% | +49.7% |
| Operating MarginEBIT ÷ Revenue | -6.1% | -8.3% |
| Net MarginNet income ÷ Revenue | -5.4% | -22.6% |
| FCF MarginFCF ÷ Revenue | -4.0% | -27.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -76.8% |
| EPS Growth (YoY)Latest quarter vs prior year | +38.2% | -100.3% |
Valuation Metrics
RAPP leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $1.5B | $5.3B |
| Enterprise ValueMkt cap + debt − cash | $1.4B | $4.9B |
| Trailing P/EPrice ÷ TTM EPS | -13.96x | 8.29x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | 5.42x |
| Price / SalesMarket cap ÷ Revenue | — | 3.09x |
| Price / BookPrice ÷ Book value/share | 3.87x | — |
| Price / FCFMarket cap ÷ FCF | — | 7.61x |
Profitability & Efficiency
PTCT leads this category, winning 4 of 5 comparable metrics.
Profitability & Efficiency
On the Piotroski fundamental quality scale (0–9), PTCT scores 7/9 vs RAPP's 2/9, reflecting strong financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -24.8% | — |
| ROA (TTM)Return on assets | -23.4% | -6.8% |
| ROICReturn on invested capital | -27.1% | — |
| ROCEReturn on capital employed | -31.3% | +55.9% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 7 |
| Debt / EquityFinancial leverage | 0.02x | — |
| Net DebtTotal debt minus cash | -$41M | -$492M |
| Cash & Equiv.Liquid assets | $53M | $985M |
| Total DebtShort + long-term debt | $11M | $492M |
| Interest CoverageEBIT ÷ Interest expense | — | -1.67x |
Total Returns (Dividends Reinvested)
RAPP leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in RAPP five years ago would be worth $19,197 today (with dividends reinvested), compared to $16,026 for PTCT. Over the past 12 months, RAPP leads with a +290.7% total return vs PTCT's +58.2%. The 3-year compound annual growth rate (CAGR) favors RAPP at 24.3% vs PTCT's 5.1% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +42.0% | -16.0% |
| 1-Year ReturnPast 12 months | +290.7% | +58.2% |
| 3-Year ReturnCumulative with dividends | +92.0% | +16.1% |
| 5-Year ReturnCumulative with dividends | +92.0% | +60.3% |
| 10-Year ReturnCumulative with dividends | +92.0% | +733.2% |
| CAGR (3Y)Annualised 3-year return | +24.3% | +5.1% |
Risk & Volatility
Evenly matched — RAPP and PTCT each lead in 1 of 2 comparable metrics.
Risk & Volatility
PTCT is the less volatile stock with a 1.13 beta — it tends to amplify market swings less than RAPP's 1.55 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. RAPP currently trades 94.5% from its 52-week high vs PTCT's 73.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.55x | 1.13x |
| 52-Week HighHighest price in past year | $42.27 | $87.50 |
| 52-Week LowLowest price in past year | $7.73 | $37.94 |
| % of 52W HighCurrent price vs 52-week peak | +94.5% | +73.7% |
| RSI (14)Momentum oscillator 0–100 | 61.9 | 45.3 |
| Avg Volume (50D)Average daily shares traded | 335K | 1.0M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates RAPP as "Buy" and PTCT as "Buy". Consensus price targets imply 39.0% upside for PTCT (target: $90) vs 22.7% for RAPP (target: $49).
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $49.00 | $89.67 |
| # AnalystsCovering analysts | 5 | 26 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
PTCT leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). RAPP leads in 2 (Valuation Metrics, Total Returns). 1 tied.
RAPP vs PTCT: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is RAPP or PTCT a better buy right now?
PTC Therapeutics, Inc.
(PTCT) offers the better valuation at 8. 3x trailing P/E, making it the more compelling value choice. Analysts rate Rapport Therapeutics, Inc. Common Stock (RAPP) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — RAPP or PTCT?
Over the past 5 years, Rapport Therapeutics, Inc.
Common Stock (RAPP) delivered a total return of +92. 0%, compared to +60. 3% for PTC Therapeutics, Inc. (PTCT). Over 10 years, the gap is even starker: PTCT returned +733. 2% versus RAPP's +92. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — RAPP or PTCT?
By beta (market sensitivity over 5 years), PTC Therapeutics, Inc.
(PTCT) is the lower-risk stock at 1. 13β versus Rapport Therapeutics, Inc. Common Stock's 1. 55β — meaning RAPP is approximately 37% more volatile than PTCT relative to the S&P 500.
04Which is growing faster — RAPP or PTCT?
On earnings-per-share growth, the picture is similar: PTC Therapeutics, Inc.
grew EPS 264. 5% year-over-year, compared to 24. 3% for Rapport Therapeutics, Inc. Common Stock. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — RAPP or PTCT?
PTC Therapeutics, Inc.
(PTCT) is the more profitable company, earning 39. 4% net margin versus -536. 4% for Rapport Therapeutics, Inc. Common Stock — meaning it keeps 39. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: PTCT leads at 49. 5% versus -611. 0% for RAPP. At the gross margin level — before operating expenses — PTCT leads at 95. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — RAPP or PTCT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is RAPP or PTCT better for a retirement portfolio?
For long-horizon retirement investors, PTC Therapeutics, Inc.
(PTCT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 13), +733. 2% 10Y return). Rapport Therapeutics, Inc. Common Stock (RAPP) carries a higher beta of 1. 55 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (PTCT: +733. 2%, RAPP: +92. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between RAPP and PTCT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: RAPP is a small-cap quality compounder stock; PTCT is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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