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PTC Therapeutics, Inc. (PTCT) 10-Year Financial Performance & Capital Metrics

PTCT •
HealthcareBiotechnologyCommercial Rare Disease Biopharma
AboutPTC Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of medicines to patients with rare disorders. Its portfolio pipeline includes commercial products and product candidates in various stages of development, including clinical, pre-clinical and research and discovery stages, focuses on the development of treatments for multiple therapeutic areas, such as rare diseases. The company offers Translarna and Emflaza for the treatment of Duchenne muscular dystrophy in the European Economic Area and the United States, as well as to treat nonsense mutation Duchenne muscular dystrophy in Brazil and Russia; commercializes Tegsedi and Waylivra for the treatment of rare diseases in Latin America and the Caribbean; and markets Evrysdi for the treatment of spinal muscular atrophy in adults and children two months and older in Brazil. The company's splicing platform includes PTC518, which is being developed for the treatment of Huntington's disease. PTC Therapeutics, Inc. has collaborations with F. Hoffman-La Roche Ltd and Hoffman-La Roche Inc., as well as the Spinal Muscular Atrophy Foundation to advance drug discovery and development research in regenerative medicine; and Akcea Therapeutics, Inc. to commercialize Tegsedi and Waylivra for the treatment of rare diseases in Latin America and the Caribbean. PTC Therapeutics, Inc. was incorporated in 1998 and is headquartered in South Plainfield, New Jersey.Show more
  • Revenue $1.73B +114.5%
  • EBITDA $867M +482.1%
  • Net Income $683M +287.9%
  • EPS (Diluted) 7.78 +264.5%
  • Gross Margin -
  • EBITDA Margin 50.09% +278.1%
  • Operating Margin 50.09% +233.6%
  • Net Margin 39.44% +187.6%
  • ROE -
  • ROIC -
  • Debt/Equity -
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Strong 5Y sales CAGR of 35.4%

✗Weaknesses

  • ✗Shares diluted 14.9% in last year

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y46.99%
5Y35.37%
3Y35.3%
TTM97.54%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM265.87%

EPS CAGR

10Y-
5Y-
3Y-
TTM244.11%

ROCE

10Y Avg-19.52%
5Y Avg-11.46%
3Y Avg-0.73%
Latest56.77%

Peer Comparison

Commercial Rare Disease Biopharma
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
CORTCorcept Therapeutics Incorporated3.78B35.7043.5412.79%13.01%15.3%3.75%0.01
BMRNBioMarin Pharmaceutical Inc.11.86B61.7334.2910.83%5.73%6.11%0.10
VRTXVertex Pharmaceuticals Incorporated126.19B496.8332.438.9%31.35%21.22%2.53%0.20
CPRXCatalyst Pharmaceuticals, Inc.2.83B23.0813.7419.78%36.39%22.46%7.38%0.00
HRMYHarmony Biosciences Holdings, Inc.1.65B28.5410.5321.51%18.27%18.24%21.12%0.02
PTCTPTC Therapeutics, Inc.5.45B68.198.76114.51%42.25%
BCRXBioCryst Pharmaceuticals, Inc.1.86B8.757.2394.1%30.16%18.63%
RAREUltragenyx Pharmaceutical Inc.2.26B23.39-3.7229.01%-91.95%-35.88%0.15

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Profit & Loss

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Sales/Revenue+82.7M194.39M264.73M306.98M380.77M538.59M698.8M937.82M806.78M1.73B
Revenue Growth %124.95%135.04%36.19%15.96%24.04%41.45%29.75%34.2%-13.97%114.51%
Cost of Goods Sold+117.63M4.58M12.67M12.13M18.94M32.33M44.68M65.49M57.4M0
COGS % of Revenue142.23%2.35%4.79%3.95%4.97%6%6.39%6.98%7.11%-
Gross Profit+-34.93M189.81M252.06M294.85M361.82M506.26M654.12M872.34M749.38M0
Gross Margin %-42.23%97.65%95.21%96.05%95.03%94%93.61%93.02%92.89%-
Gross Profit Growth %58.93%643.45%32.79%16.97%22.72%39.92%29.21%33.36%-14.09%-100%
Operating Expenses+214.76M254.11M348.41M536M793.59M880.71M1.1B1.31B1.05B863.72M
OpEx % of Revenue259.67%130.72%131.61%174.61%208.42%163.52%157.63%139.88%130.39%49.91%
Selling, General & Admin97.13M121.27M153.55M202.54M245.16M285.77M326M332.54M300.91M347.14M
SG&A % of Revenue117.44%62.38%58%65.98%64.39%53.06%46.65%35.46%37.3%20.06%
Research & Development117.63M117.46M171.98M257.45M477.64M540.68M651.5M666.56M534.48M455.25M
R&D % of Revenue142.23%60.42%64.96%83.87%125.44%100.39%93.23%71.08%66.25%26.3%
Other Operating Expenses-1.21M-1.28M129K76.01M70.78M54.25M124.04M312.74M216.56M61.33M
Operating Income+-132.06M-64.29M-115.69M-241.16M-431.77M-374.44M-447.41M-439.5M-302.57M866.93M
Operating Margin %-159.67%-33.07%-43.7%-78.56%-113.39%-69.52%-64.03%-46.86%-37.5%50.09%
Operating Income Growth %20.98%51.32%-79.94%-108.46%-79.04%13.28%-19.49%1.77%31.16%386.52%
EBITDA+-128.77M-46.61M-89.6M-208.98M-388.28M-310.31M-318.57M-202.91M-226.91M866.93M
EBITDA Margin %-155.7%-23.98%-33.84%-68.08%-101.97%-57.61%-45.59%-21.64%-28.13%50.09%
EBITDA Growth %21.6%63.8%-92.23%-133.24%-85.8%20.08%-2.66%36.31%-11.83%482.07%
D&A (Non-Cash Add-back)3.29M17.68M26.09M32.18M43.49M64.13M128.84M236.59M75.66M0
EBIT-132.06M-64.29M-115.56M-227.44M-346.58M-432.32M-496.62M-566.93M-196.13M0
Net Interest Income+-8.28M-12.09M-12.55M-12.49M-56.35M-86.02M-90.87M-129.18M-166.99M0
Interest Income0000000000
Interest Expense8.28M12.09M12.55M12.49M56.35M86.02M90.87M129.18M166.99M-152.23M
Other Income/Expense-9.48M-13.37M-12.43M1.23M28.84M-143.9M-140.08M-256.61M-60.55M-170.32M
Pretax Income+-141.54M-77.67M-128.11M-239.93M-402.93M-518.34M-587.49M-696.11M-363.12M696.62M
Pretax Margin %-171.14%-39.95%-48.39%-78.16%-105.82%-96.24%-84.07%-74.23%-45.01%40.25%
Income Tax+569K1.33M-29K11.65M35.23M5.56M-28.47M-69.51M176K-13.97M
Effective Tax Rate %100.4%101.72%99.98%104.86%108.74%101.07%95.15%90.02%100.05%97.99%
Net Income+-142.11M-79M-128.08M-251.58M-438.16M-523.9M-559.02M-626.6M-363.3M682.64M
Net Margin %-171.83%-40.64%-48.38%-81.95%-115.07%-97.27%-80%-66.81%-45.03%39.44%
Net Income Growth %16.63%44.41%-62.13%-96.42%-74.17%-19.57%-6.7%-12.09%42.02%287.9%
Net Income (Continuing)-142.11M-79M-128.08M-251.58M-438.16M-523.9M-559.02M-626.6M-363.3M682.64M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-4.17-2.02-2.75-4.27-6.64-7.43-7.79-8.37-4.737.78
EPS Growth %17.75%51.56%-36.14%-55.27%-55.5%-11.9%-4.85%-7.45%43.49%264.48%
EPS (Basic)-4.17-2.02-2.75-4.27-6.64-7.43-7.79-8.37-4.738.58
Diluted Shares Outstanding34.04M39.18M46.58M58.86M66.03M70.47M71.73M74.84M76.85M88.31M
Basic Shares Outstanding34.04M39.11M46.58M58.86M66.03M70.47M71.73M74.84M76.85M79.53M
Dividend Payout Ratio----------

Balance Sheet

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Current Assets+261.29M249.06M320.86M779.28M1.23B954.37M693.78M1.22B1.37B2.27B
Cash & Short-Term Investments231.67M191.25M227.59M686.56M1.1B773.38M410.7M876.74M1.14B1.95B
Cash Only231.67M191.25M227.59M288.03M208.81M189.72M279.83M594M779.71M984.65M
Short-Term Investments000398.54M894.84M583.66M130.87M282.74M359.99M960.72M
Accounts Receivable24.93M40.39M67.91M55.54M69.93M110.45M155.61M160.82M158.55M181.62M
Days Sales Outstanding110.0275.8593.6366.0367.0374.8581.2862.5971.7338.3
Inventory010.75M16.12M19.29M18.7M15.86M21.81M30.58M23.19M79.65M
Days Inventory Outstanding-857.59464.3580.06360.28179.02178.16170.43147.49-
Other Current Assets4.69M6.67M9.25M000105.66M150.49M44.09M67.31M
Total Non-Current Assets+8.06M142.59M798.37M844.5M976.53M983.69M1.01B677.07M339.49M624.82M
Property, Plant & Equipment7.43M8.38M12.69M35.24M118.24M130.01M175.02M178.99M117.66M135.42M
Fixed Asset Turnover11.13x23.21x20.86x8.71x3.22x4.14x3.99x5.24x6.86x12.78x
Goodwill0082.34M82.34M82.34M82.34M82.34M82.34M82.34M82.34M
Intangible Assets0132.99M701.03M710.5M715.33M724.84M705.89M379.5M118.79M388.75M
Long-Term Investments0000000000
Other Non-Current Assets630K1.22M2.3M16.41M60.62M46.5M48.58M36.25M20.7M18.3M
Total Assets+269.35M391.65M1.12B1.62B2.21B1.94B1.71B1.9B1.71B2.9B
Asset Turnover0.31x0.50x0.24x0.19x0.17x0.28x0.41x0.49x0.47x0.60x
Asset Growth %-26.82%45.41%185.77%45.08%36%-12.24%-11.99%11.14%-10.06%70.01%
Total Current Liabilities+49.62M82.05M166.8M235.86M277.33M509.35M406.24M603.1M580.98M968.43M
Accounts Payable6.3M15.28M6M10.32M18.66M23.03M27.27M6.04M17.27M0
Days Payables Outstanding19.541.22K172.88310.53359.66260.05222.7733.69109.85-
Short-Term Debt0011.67M20M0208.83M72.15M194.31M257.82M302.12M
Deferred Revenue (Current)1.59M3.94M3.72M8.24M4.15M01.35M801K5.5M2.04M
Other Current Liabilities29.68M45.12M117.78M120.16M129.89M118.86M126.46M139.82M120.22M664.27M
Current Ratio5.27x3.04x1.92x3.30x4.44x1.87x1.71x2.02x2.35x2.35x
Quick Ratio5.27x2.90x1.83x3.22x4.37x1.84x1.65x1.97x2.31x2.27x
Cash Conversion Cycle--285.25385.05335.5767.65-6.1836.67199.33109.38-
Total Non-Current Liabilities+100.14M153.17M601.7M793.6M1.45B1.43B1.65B2.11B2.22B2.14B
Long-Term Debt98.22M144.97M141.35M293.86M309.14M956.59M1.26B1.9B2.11B96.58M
Capital Lease Obligations0009.02M102.55M93.67M119.53M114.81M90.52M0
Deferred Tax Liabilities0-3.94M122.03M130.86M136.74M137.11M102.83M55.91M00
Other Non-Current Liabilities335K243K328.6M356.44M900.53M239.9M166.64M36.44M22.23M2.04B
Total Liabilities149.76M235.22M768.5M1.03B1.73B1.94B2.05B2.71B2.8B3.1B
Total Debt+98.22M144.97M153.01M328.03M420.44M1.27B1.46B2.23B2.47B398.7M
Net Debt-133.45M-46.27M-74.57M40M211.63M1.08B1.18B1.64B1.69B-585.95M
Debt / Equity0.82x0.93x0.44x0.55x0.87x882.73x----
Debt / EBITDA---------0.46x
Net Debt / EBITDA----------0.68x
Interest Coverage-15.96x-5.32x-9.21x-19.31x-7.66x-4.35x-4.92x-3.40x-1.81x-
Total Equity+119.58M156.44M350.73M594.33M481.98M1.44M-347.09M-818.55M-1.1B-205.31M
Equity Growth %-59.93%30.82%124.2%69.46%-18.9%-99.7%-24236.72%-135.84%-34.15%81.3%
Book Value per Share3.513.997.5310.107.300.02-4.84-10.94-14.29-2.32
Total Shareholders' Equity119.58M156.44M350.73M594.33M481.98M1.44M-347.09M-818.55M-1.1B-205.31M
Common Stock34K42K51K62K70K71K72K75K77K80K
Retained Earnings-735.11M-814.11M-938.92M-1.19B-1.63B-2.1B-2.66B-3.28B-3.65B-2.96B
Treasury Stock0000000000
Accumulated OCI-1.49M3.97M1.46M-10.58M-60.96M-24.28M4.8M-1.28M-25.89M10.5M
Minority Interest0000000000

Cash Flow

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Cash from Operations+-103.57M-10.06M-27.64M-98.64M-194.07M-251.33M-356.65M-158.42M-107.69M0
Operating CF Margin %-125.22%-5.18%-10.44%-32.13%-50.97%-46.66%-51.04%-16.89%-13.35%-
Operating CF Growth %16.71%90.28%-174.68%-256.86%-96.75%-29.51%-41.91%55.58%32.02%100%
Net Income-142.11M-79M-128.08M-251.58M-438.16M-523.9M-559.02M-626.6M-363.3M0
Depreciation & Amortization3.29M17.68M26.09M32.18M84.87M64.13M128.84M236.59M75.66M0
Stock-Based Compensation35.01M30.56M33.25M42.13M70.33M103.51M110.33M131.21M74.61M73.74M
Deferred Taxes-199K199K-490K8.83M5.87M377K-34.28M-46.93M-55.91M0
Other Non-Cash Items9.41M7.27M27.38M49.37M46.11M128.33M82.81M151.32M58.7M-73.74M
Working Capital Changes-8.96M13.23M14.21M20.43M36.91M-23.79M-85.33M-4M102.54M0
Change in Receivables-14.84M-12.2M-29.59M11.53M-10.48M-44.99M-48.47M-1.54M1.73M0
Change in Inventory893K-6.45M-5.82M-3.46M1.84M1.8M-6.67M-8.18M6.16M0
Change in Payables4.26M24.01M43.11M13.75M53.59M23.41M27.54M0045.49M
Cash from Investing+104.48M13.12M-42.61M-387.24M-561.55M219.18M290.18M-176.74M44.18M0
Capital Expenditures-1.78M-3.1M-15.53M-45.44M-55.98M-85.33M-152.46M-28.44M-6.5M0
CapEx % of Revenue2.15%1.6%5.87%14.8%14.7%15.84%21.82%3.03%0.81%-
Acquisitions0-77.16M-48.89M-4M38.13M57.12M128.44M000
Investments----------
Other Investing106.26M16.22M13.38M0-38.13M-57.12M-128.44M-92.18M110.31M0
Cash from Financing+968K44.22M131.57M613.21M668.72M20.88M167.95M646.4M255.87M0
Debt Issued (Net)040M0267.6M-46.16M-2.22M148.72M-301.38M-1.49M0
Equity Issued (Net)001000K1000K1000K1000K1000K000
Dividends Paid0000000000
Share Repurchases0000000000
Other Financing968K4.22M13.65M21.85M686.78M0-30.77M947.78M257.36M0
Net Change in Cash299K53.47M57.71M126.03M-79.22M-19.09M98.71M314.36M185.03M0
Free Cash Flow+-105.34M-13.16M-43.17M-144.08M-250.05M-336.66M-509.11M-279.04M-181.94M0
FCF Margin %-127.37%-6.77%-16.31%-46.93%-65.67%-62.51%-72.86%-29.75%-22.55%-
FCF Growth %17.09%87.5%-227.95%-233.74%-73.55%-34.64%-51.22%45.19%34.8%100%
FCF per Share-3.09-0.34-0.93-2.45-3.79-4.78-7.10-3.73-2.37-
FCF Conversion (FCF/Net Income)0.73x0.13x0.22x0.39x0.44x0.48x0.64x0.25x0.30x-
Interest Paid4.51M6.27M7.77M7.69M9.8M9.59M18.46M36.13M5.82M0
Taxes Paid943K1.1M1.58M2.11M26.4M7.71M4.92M14.15M17.55M0

Key Ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-67.99%-57.24%-50.51%-53.24%-81.42%-216.75%----
Return on Invested Capital (ROIC)-491.74%-100.15%-44.92%-39.73%-48.77%-31.65%-35.03%-39.93%-32.19%-
Gross Margin-42.23%97.65%95.21%96.05%95.03%94%93.61%93.02%92.89%-
Net Margin-171.83%-40.64%-48.38%-81.95%-115.07%-97.27%-80%-66.81%-45.03%39.44%
Debt / Equity0.82x0.93x0.44x0.55x0.87x882.73x----
Interest Coverage-15.96x-5.32x-9.21x-19.31x-7.66x-4.35x-4.92x-3.40x-1.81x-
FCF Conversion0.73x0.13x0.22x0.39x0.44x0.48x0.64x0.25x0.30x-
Revenue Growth124.95%135.04%36.19%15.96%24.04%41.45%29.75%34.2%-13.97%114.51%

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