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PTCT logoPTC Therapeutics, Inc.(PTCT)Earnings, Financials & Key Ratios

PTCT•NASDAQ
$66.61
$5.52B mkt cap·8.6× P/E·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Rare Disease Biopharma
AboutPTC Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of medicines to patients with rare disorders. Its portfolio pipeline includes commercial products and product candidates in various stages of development, including clinical, pre-clinical and research and discovery stages, focuses on the development of treatments for multiple therapeutic areas, such as rare diseases. The company offers Translarna and Emflaza for the treatment of Duchenne muscular dystrophy in the European Economic Area and the United States, as well as to treat nonsense mutation Duchenne muscular dystrophy in Brazil and Russia; commercializes Tegsedi and Waylivra for the treatment of rare diseases in Latin America and the Caribbean; and markets Evrysdi for the treatment of spinal muscular atrophy in adults and children two months and older in Brazil. The company's splicing platform includes PTC518, which is being developed for the treatment of Huntington's disease. PTC Therapeutics, Inc. has collaborations with F. Hoffman-La Roche Ltd and Hoffman-La Roche Inc., as well as the Spinal Muscular Atrophy Foundation to advance drug discovery and development research in regenerative medicine; and Akcea Therapeutics, Inc. to commercialize Tegsedi and Waylivra for the treatment of rare diseases in Latin America and the Caribbean. PTC Therapeutics, Inc. was incorporated in 1998 and is headquartered in South Plainfield, New Jersey.Show more
  • Revenue$1.73B+114.5%
  • EBITDA$895M+494.6%
  • Net Income$683M+287.9%
  • EPS (Diluted)7.78+264.5%
  • Gross Margin95.85%+3.2%
  • EBITDA Margin51.73%+283.9%
  • Operating Margin49.49%+232.0%
  • Net Margin39.44%+187.6%
  • Interest Coverage5.58+574.8%
Technical→

PTCT Key Insights

PTC Therapeutics, Inc. (PTCT) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Strong Piotroski F-Score: 7/9
  • ✓FCF machine: 40.6% free cash flow margin
  • ✓Strong 5Y sales CAGR of 35.4%

✗Weaknesses

  • ✗Shares diluted 14.9% in last year

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

PTCT Price & Volume

PTC Therapeutics, Inc. (PTCT) stock price & volume — 10-year historical chart

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PTCT Growth Metrics

PTC Therapeutics, Inc. (PTCT) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years46.99%
5 Years35.37%
3 Years35.3%
TTM114.51%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM287.9%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM263.64%

Return on Capital

10 Years-19.61%
5 Years-11.64%
3 Years-1.03%
Last Year55.86%

PTCT Recent Earnings

PTC Therapeutics, Inc. (PTCT) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 6/12 qtrs (50%)
Q1 2026Latest
Feb 19, 2026
EPS
$1.67
Est $0.21
-695.2%
Revenue
$165M
Est $279M
-41.1%
Q4 2025
Nov 4, 2025
EPS
$0.20
Est $1.19
+116.8%
Revenue
$211M
Est $281M
-25.0%
Q3 2025
Aug 7, 2025
EPS
$0.83
Est $1.07
+22.4%
Revenue
$179M
Est $191M
-6.6%
Q2 2025
May 6, 2025
EPS
$10.04
Est $1.08
+1029.6%
Revenue
$1.2B
Est $373M
+215.6%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q1 2026LatestFeb 19, 2026
$1.67vs $0.21-695.2%
$165Mvs $279M-41.1%
Q4 2025Nov 4, 2025
$0.20vs $1.19+116.8%
$211Mvs $281M-25.0%
Q3 2025Aug 7, 2025
$0.83vs $1.07+22.4%
$179Mvs $191M-6.6%
Q2 2025May 6, 2025
$10.04vs $1.08+1029.6%
$1.2Bvs $373M+215.6%
Based on last 12 quarters of dataView full earnings history →

PTCT Peer Comparison

PTC Therapeutics, Inc. (PTCT) competitors in Commercial Rare Disease Biopharma — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
SRPT logoSRPTSarepta Therapeutics, Inc.Direct Competitor2.42B23.03-3.2315.58%2.98%4.89%0.91
BMRN logoBMRNBioMarin Pharmaceutical Inc.Direct Competitor10.5B54.6030.3312.87%8.29%4.41%0.11
RARE logoRAREUltragenyx Pharmaceutical Inc.Direct Competitor2.55B25.93-4.4520.13%-91.03%-6.08%
ALNY logoALNYAlnylam Pharmaceuticals, Inc.Direct Competitor40.43B303.00130.0465.19%13.46%98.29%1.62
ACAD logoACADACADIA Pharmaceuticals Inc.Direct Competitor3.68B21.489.3811.87%36.49%41.9%0.04
FOLD logoFOLDAmicus Therapeutics, Inc.Product Competitor4.47B14.49-80.5032.29%-2.35%-6.1%2.29
KRYS logoKRYSKrystal Biotech, Inc.Product Competitor8.52B288.9042.2433.94%53.92%19.25%0.01
RYTM logoRYTMRhythm Pharmaceuticals, Inc.Product Competitor6.6B96.61-31.0645.83%-93.84%-204.35%1.77

Compare PTCT vs Peers

PTC Therapeutics, Inc. (PTCT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SRPT

Most directly comparable listed peer for PTCT.

Scale Benchmark

vs VRTX

Larger-name benchmark to compare PTCT against a more recognizable public peer.

Peer Set

Compare Top 5

vs SRPT, BMRN, RARE, ALNY

PTCT Income Statement

PTC Therapeutics, Inc. (PTCT) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue194.39M264.73M306.98M380.77M538.59M698.8M937.82M806.78M1.73B
Revenue Growth %135.04%36.19%15.96%24.04%41.45%29.75%34.2%-13.97%114.51%
Cost of Goods Sold4.58M12.67M12.13M18.94M32.33M44.68M65.49M57.4M71.75M
COGS % of Revenue2.35%4.79%3.95%4.97%6%6.39%6.98%7.11%4.15%
Gross Profit
189.81M▲ 0%
252.06M▲ 32.8%
294.85M▲ 17.0%
361.82M▲ 22.7%
506.26M▲ 39.9%
654.12M▲ 29.2%
872.34M▲ 33.4%
749.38M▼ 14.1%
1.66B▲ 121.4%
Gross Margin %97.65%95.21%96.05%95.03%94%93.61%93.02%92.89%95.85%
Gross Profit Growth %643.45%32.79%16.97%22.72%39.92%29.21%33.36%-14.09%121.37%
Operating Expenses254.11M348.41M536M793.59M880.71M1.1B1.31B1.05B802.39M
OpEx % of Revenue130.72%131.61%174.61%208.42%163.52%157.63%139.88%130.39%46.36%
Selling, General & Admin121.27M153.55M202.54M245.16M285.77M326M332.54M300.91M347.14M
SG&A % of Revenue62.38%58%65.98%64.39%53.06%46.65%35.46%37.3%20.06%
Research & Development117.46M171.98M257.45M477.64M540.68M651.5M666.56M534.48M455.25M
R&D % of Revenue60.42%64.96%83.87%125.44%100.39%93.23%71.08%66.25%26.3%
Other Operating Expenses-1.28M129K76.01M70.78M54.25M124.04M312.74M216.56M0
Operating Income
-64.29M▲ 0%
-115.69M▼ 79.9%
-241.16M▼ 108.5%
-431.77M▼ 79.0%
-374.44M▲ 13.3%
-447.41M▼ 19.5%
-439.5M▲ 1.8%
-302.57M▲ 31.2%
856.51M▲ 383.1%
Operating Margin %-33.07%-43.7%-78.56%-113.39%-69.52%-64.03%-46.86%-37.5%49.49%
Operating Income Growth %51.32%-79.94%-108.46%-79.04%13.28%-19.49%1.77%31.16%383.08%
EBITDA-46.61M-89.6M-208.98M-388.28M-310.31M-318.57M-202.91M-226.91M895.32M
EBITDA Margin %-23.98%-33.84%-68.08%-101.97%-57.61%-45.59%-21.64%-28.13%51.73%
EBITDA Growth %63.8%-92.23%-133.24%-85.8%20.08%-2.66%36.31%-11.83%494.58%
D&A (Non-Cash Add-back)17.68M26.09M32.18M43.49M64.13M128.84M236.59M75.66M38.81M
EBIT-64.29M-115.56M-227.44M-346.58M-432.32M-496.62M-566.93M-196.13M848.85M
Net Interest Income-12.09M-12.55M-12.49M-56.35M-86.02M-90.87M-129.18M-166.99M-152.23M
Interest Income000000000
Interest Expense12.09M12.55M12.49M56.35M86.02M90.87M129.18M166.99M152.23M
Other Income/Expense-13.37M-12.43M1.23M28.84M-143.9M-140.08M-256.61M-60.55M-159.89M
Pretax Income
-77.67M▲ 0%
-128.11M▼ 65.0%
-239.93M▼ 87.3%
-402.93M▼ 67.9%
-518.34M▼ 28.6%
-587.49M▼ 13.3%
-696.11M▼ 18.5%
-363.12M▲ 47.8%
696.62M▲ 291.8%
Pretax Margin %-39.95%-48.39%-78.16%-105.82%-96.24%-84.07%-74.23%-45.01%40.25%
Income Tax1.33M-29K11.65M35.23M5.56M-28.47M-69.51M176K13.97M
Effective Tax Rate %-1.72%0.02%-4.86%-8.74%-1.07%4.85%9.98%-0.05%2.01%
Net Income
-79M▲ 0%
-128.08M▼ 62.1%
-251.58M▼ 96.4%
-438.16M▼ 74.2%
-523.9M▼ 19.6%
-559.02M▼ 6.7%
-626.6M▼ 12.1%
-363.3M▲ 42.0%
682.64M▲ 287.9%
Net Margin %-40.64%-48.38%-81.95%-115.07%-97.27%-80%-66.81%-45.03%39.44%
Net Income Growth %44.41%-62.13%-96.42%-74.17%-19.57%-6.7%-12.09%42.02%287.9%
Net Income (Continuing)-79M-128.08M-251.58M-438.16M-523.9M-559.02M-626.6M-363.3M682.64M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)
-2.02▲ 0%
-2.75▼ 36.1%
-4.27▼ 55.3%
-6.64▼ 55.5%
-7.43▼ 11.9%
-7.79▼ 4.8%
-8.37▼ 7.4%
-4.73▲ 43.5%
7.78▲ 264.5%
EPS Growth %51.56%-36.14%-55.27%-55.5%-11.9%-4.85%-7.45%43.49%264.48%
EPS (Basic)-2.02-2.75-4.27-6.64-7.43-7.79-8.37-4.738.58
Diluted Shares Outstanding39.18M46.58M58.86M66.03M70.47M71.73M74.84M76.85M88.31M
Basic Shares Outstanding39.11M46.58M58.86M66.03M70.47M71.73M74.84M76.85M79.53M
Dividend Payout Ratio---------

PTCT Balance Sheet

PTC Therapeutics, Inc. (PTCT) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets249.06M320.86M779.28M1.23B954.37M693.78M1.22B1.37B2.27B
Cash & Short-Term Investments191.25M227.59M686.56M1.1B773.38M410.7M876.74M1.14B1.95B
Cash Only191.25M227.59M288.03M208.81M189.72M279.83M594M779.71M984.65M
Short-Term Investments00398.54M894.84M583.66M130.87M282.74M359.99M960.72M
Accounts Receivable40.39M67.91M55.54M69.93M110.45M155.61M160.82M158.55M181.62M
Days Sales Outstanding75.8593.6366.0367.0374.8581.2862.5971.7338.3
Inventory10.75M16.12M19.29M18.7M15.86M21.81M30.58M23.19M79.65M
Days Inventory Outstanding857.59464.3580.06360.28179.02178.16170.43147.49405.14
Other Current Assets6.67M9.25M000105.66M150.49M44.09M67.31M
Total Non-Current Assets142.59M798.37M844.5M976.53M983.69M1.01B677.07M339.49M637.3M
Property, Plant & Equipment8.38M12.69M35.24M118.24M130.01M175.02M178.99M117.66M135.42M
Fixed Asset Turnover23.21x20.86x8.71x3.22x4.14x3.99x5.24x6.86x12.78x
Goodwill082.34M82.34M82.34M82.34M82.34M82.34M82.34M82.34M
Intangible Assets132.99M701.03M710.5M715.33M724.84M705.89M379.5M118.79M388.75M
Long-Term Investments0000000013.69M
Other Non-Current Assets1.22M2.3M16.41M60.62M46.5M48.58M36.25M20.7M4.62M
Total Assets
391.65M▲ 0%
1.12B▲ 185.8%
1.62B▲ 45.1%
2.21B▲ 36.0%
1.94B▼ 12.2%
1.71B▼ 12.0%
1.9B▲ 11.1%
1.71B▼ 10.1%
2.91B▲ 70.7%
Asset Turnover0.50x0.24x0.19x0.17x0.28x0.41x0.49x0.47x0.59x
Asset Growth %45.41%185.77%45.08%36%-12.24%-11.99%11.14%-10.06%70.75%
Total Current Liabilities82.05M166.8M235.86M277.33M509.35M406.24M603.1M580.98M968.43M
Accounts Payable15.28M6M10.32M18.66M23.03M27.27M6.04M17.27M45.49M
Days Payables Outstanding1.22K172.88310.53359.66260.05222.7733.69109.85231.38
Short-Term Debt011.67M20M0208.83M72.15M194.31M257.82M302.12M
Deferred Revenue (Current)3.94M3.72M8.24M4.15M01.35M801K5.5M2.04M
Other Current Liabilities45.12M117.78M120.16M129.89M118.86M126.46M139.82M120.22M540.37M
Current Ratio3.04x1.92x3.30x4.44x1.87x1.71x2.02x2.35x2.35x
Quick Ratio2.90x1.83x3.22x4.37x1.84x1.65x1.97x2.31x2.27x
Cash Conversion Cycle-285.25385.05335.5767.65-6.1836.67199.33109.38212.07
Total Non-Current Liabilities153.17M601.7M793.6M1.45B1.43B1.65B2.11B2.22B2.15B
Long-Term Debt144.97M141.35M293.86M309.14M956.59M1.26B1.9B2.11B93.58M
Capital Lease Obligations009.02M102.55M93.67M119.53M114.81M90.52M96.58M
Deferred Tax Liabilities-3.94M122.03M130.86M136.74M137.11M102.83M55.91M012.48M
Other Non-Current Liabilities243K328.6M356.44M900.53M239.9M166.64M36.44M22.23M1.95B
Total Liabilities235.22M768.5M1.03B1.73B1.94B2.05B2.71B2.8B3.12B
Total Debt144.97M153.01M328.03M420.44M1.27B1.46B2.23B2.47B492.28M
Net Debt-46.27M-74.57M40M211.63M1.08B1.18B1.64B1.69B-492.37M
Debt / Equity0.93x0.44x0.55x0.87x882.73x----
Debt / EBITDA--------0.55x
Net Debt / EBITDA---------0.55x
Interest Coverage-5.32x-9.20x-18.21x-6.15x-5.03x-5.47x-4.39x-1.17x5.58x
Total Equity
156.44M▲ 0%
350.73M▲ 124.2%
594.33M▲ 69.5%
481.98M▼ 18.9%
1.44M▼ 99.7%
-347.09M▼ 24236.7%
-818.55M▼ 135.8%
-1.1B▼ 34.1%
-205.31M▲ 81.3%
Equity Growth %30.82%124.2%69.46%-18.9%-99.7%-24236.72%-135.84%-34.15%81.3%
Book Value per Share3.997.5310.107.300.02-4.84-10.94-14.29-2.32
Total Shareholders' Equity156.44M350.73M594.33M481.98M1.44M-347.09M-818.55M-1.1B-205.31M
Common Stock42K51K62K70K71K72K75K77K80K
Retained Earnings-814.11M-938.92M-1.19B-1.63B-2.1B-2.66B-3.28B-3.65B-2.96B
Treasury Stock000000000
Accumulated OCI3.97M1.46M-10.58M-60.96M-24.28M4.8M-1.28M-25.89M10.5M
Minority Interest000000000

PTCT Cash Flow Statement

PTC Therapeutics, Inc. (PTCT) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations-10.06M-27.64M-98.64M-194.07M-251.33M-356.65M-158.42M-107.69M711.2M
Operating CF Margin %-5.18%-10.44%-32.13%-50.97%-46.66%-51.04%-16.89%-13.35%41.09%
Operating CF Growth %90.28%-174.68%-256.86%-96.75%-29.51%-41.91%55.58%32.02%760.42%
Net Income-79M-128.08M-251.58M-438.16M-523.9M-559.02M-626.6M-363.3M682.64M
Depreciation & Amortization17.68M26.09M32.18M84.87M64.13M128.84M236.59M75.66M38.81M
Stock-Based Compensation30.56M33.25M42.13M70.33M103.51M110.33M131.21M74.61M0
Deferred Taxes199K-490K8.83M5.87M377K-34.28M-46.93M-55.91M-3K
Other Non-Cash Items7.27M27.38M49.37M46.11M128.33M82.81M151.32M58.7M42.3M
Working Capital Changes13.23M14.21M20.43M36.91M-23.79M-85.33M-4M102.54M-52.56M
Change in Receivables-12.2M-29.59M11.53M-10.48M-44.99M-48.47M-1.54M1.73M-10.15M
Change in Inventory-6.45M-5.82M-3.46M1.84M1.8M-6.67M-8.18M6.16M-53.9M
Change in Payables24.01M43.11M13.75M53.59M23.41M27.54M000
Cash from Investing13.12M-42.61M-387.24M-561.55M219.18M290.18M-176.74M44.18M-861.98M
Capital Expenditures-3.1M-15.53M-45.44M-55.98M-85.33M-152.46M-28.44M-6.5M-300.01M
CapEx % of Revenue1.6%5.87%14.8%14.7%15.84%21.82%3.03%0.81%17.34%
Acquisitions-77.16M-48.89M-4M38.13M57.12M128.44M0070K
Investments---------
Other Investing16.22M13.38M0-38.13M-57.12M-128.44M-92.18M110.31M0
Cash from Financing44.22M131.57M613.21M668.72M20.88M167.95M646.4M255.87M331.09M
Debt Issued (Net)40M0267.6M-46.16M-2.22M148.72M-301.38M-1.49M0
Equity Issued (Net)0117.92M323.76M28.09M23.1M50M0099.05M
Dividends Paid000000000
Share Repurchases000000000
Other Financing4.22M13.65M21.85M686.78M0-30.77M947.78M257.36M232.05M
Net Change in Cash
53.47M▲ 0%
57.71M▲ 7.9%
126.03M▲ 118.4%
-79.22M▼ 162.9%
-19.09M▲ 75.9%
98.71M▲ 617.0%
314.36M▲ 218.5%
185.03M▼ 41.1%
204.94M▲ 10.8%
Free Cash Flow
-13.16M▲ 0%
-43.17M▼ 227.9%
-144.08M▼ 233.7%
-250.05M▼ 73.6%
-336.66M▼ 34.6%
-509.11M▼ 51.2%
-279.04M▲ 45.2%
-181.94M▲ 34.8%
702.34M▲ 486.0%
FCF Margin %-6.77%-16.31%-46.93%-65.67%-62.51%-72.86%-29.75%-22.55%40.58%
FCF Growth %87.5%-227.95%-233.74%-73.55%-34.64%-51.22%45.19%34.8%486.03%
FCF per Share-0.34-0.93-2.45-3.79-4.78-7.10-3.73-2.377.95
FCF Conversion (FCF/Net Income)0.13x0.22x0.39x0.44x0.48x0.64x0.25x0.30x1.04x
Interest Paid6.27M7.77M7.69M9.8M9.59M18.46M36.13M5.82M0
Taxes Paid1.1M1.58M2.11M26.4M7.71M4.92M14.15M17.55M0

PTCT Key Ratios

PTC Therapeutics, Inc. (PTCT) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-67.99%-57.24%-50.51%-53.24%-81.42%-216.75%----
Return on Invested Capital (ROIC)-491.74%-100.15%-44.92%-39.73%-48.77%-31.65%-35.03%-39.93%-32.19%-
Gross Margin-42.23%97.65%95.21%96.05%95.03%94%93.61%93.02%92.89%95.85%
Net Margin-171.83%-40.64%-48.38%-81.95%-115.07%-97.27%-80%-66.81%-45.03%39.44%
Debt / Equity0.82x0.93x0.44x0.55x0.87x882.73x----
Interest Coverage-15.96x-5.32x-9.20x-18.21x-6.15x-5.03x-5.47x-4.39x-1.17x5.58x
FCF Conversion0.73x0.13x0.22x0.39x0.44x0.48x0.64x0.25x0.30x1.04x
Revenue Growth124.95%135.04%36.19%15.96%24.04%41.45%29.75%34.2%-13.97%114.51%

PTCT SEC Filings & Documents

PTC Therapeutics, Inc. (PTCT) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 28, 2026·SEC

Material company update

Mar 25, 2026·SEC

Material company update

Feb 19, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 19, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 29, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 4, 2025·SEC

FY 2025

Aug 7, 2025·SEC

FY 2025

May 6, 2025·SEC

PTCT Frequently Asked Questions

PTC Therapeutics, Inc. (PTCT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

PTC Therapeutics, Inc. (PTCT) reported $1.73B in revenue for fiscal year 2025. This represents a 1649% increase from $99.0M in 2011.

PTC Therapeutics, Inc. (PTCT) grew revenue by 114.5% over the past year. This is strong growth.

Yes, PTC Therapeutics, Inc. (PTCT) is profitable, generating $682.6M in net income for fiscal year 2025 (39.4% net margin).

Dividend & Returns

PTC Therapeutics, Inc. (PTCT) generated $698.9M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

Explore More PTCT

PTC Therapeutics, Inc. (PTCT) financial analysis — history, returns, DCA and operating performance tools

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Valuation

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