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VCYT vs NTRA
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Diagnostics & Research
VCYT vs NTRA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Medical - Diagnostics & Research |
| Market Cap | $3.25B | $31.16B |
| Revenue (TTM) | $542M | $2.31B |
| Net Income (TTM) | $88M | $-208M |
| Gross Margin | 71.4% | 64.8% |
| Operating Margin | 12.2% | -13.4% |
| Forward P/E | 24.6x | — |
| Total Debt | $40M | $214M |
| Cash & Equiv. | $363M | $1.08B |
VCYT vs NTRA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Veracyte, Inc. (VCYT) | 100 | 163.4 | +63.4% |
| Natera, Inc. (NTRA) | 100 | 501.3 | +401.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: VCYT vs NTRA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
VCYT has the current edge in this matchup, primarily because of its strength in sleep-well-at-night.
- Lower volatility, beta 1.52, Low D/E 3.0%, current ratio 8.15x
- Better valuation composite
- 16.2% margin vs NTRA's -9.0%
NTRA is the clearest fit if your priority is income & stability and growth exposure.
- beta 1.26
- Rev growth 35.9%, EPS growth 0.7%, 3Y rev CAGR 41.1%
- 20.9% 10Y total return vs VCYT's 6.4%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 35.9% revenue growth vs VCYT's 16.0% | |
| Value | Better valuation composite | |
| Quality / Margins | 16.2% margin vs NTRA's -9.0% | |
| Stability / Safety | Beta 1.26 vs VCYT's 1.52 | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +37.3% vs VCYT's +32.2% | |
| Efficiency (ROA) | 6.3% ROA vs NTRA's -10.6%, ROIC 5.6% vs -36.1% |
VCYT vs NTRA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
VCYT vs NTRA — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
VCYT leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NTRA is the larger business by revenue, generating $2.3B annually — 4.3x VCYT's $542M. VCYT is the more profitable business, keeping 16.2% of every revenue dollar as net income compared to NTRA's -9.0%. On growth, NTRA holds the edge at +39.8% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $542M | $2.3B |
| EBITDAEarnings before interest/tax | $82M | -$310M |
| Net IncomeAfter-tax profit | $88M | -$208M |
| Free Cash FlowCash after capex | $155M | $97M |
| Gross MarginGross profit ÷ Revenue | +71.4% | +64.8% |
| Operating MarginEBIT ÷ Revenue | +12.2% | -13.4% |
| Net MarginNet income ÷ Revenue | +16.2% | -9.0% |
| FCF MarginFCF ÷ Revenue | +28.6% | +4.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | +21.5% | +39.8% |
| EPS Growth (YoY)Latest quarter vs prior year | +3.0% | +185.4% |
Valuation Metrics
VCYT leads this category, winning 3 of 4 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $3.3B | $31.2B |
| Enterprise ValueMkt cap + debt − cash | $2.9B | $30.3B |
| Trailing P/EPrice ÷ TTM EPS | 49.71x | -144.62x |
| Forward P/EPrice ÷ next-FY EPS est. | 24.57x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | 30.65x | — |
| Price / SalesMarket cap ÷ Revenue | 6.29x | 13.51x |
| Price / BookPrice ÷ Book value/share | 2.51x | 17.55x |
| Price / FCFMarket cap ÷ FCF | 25.68x | 285.53x |
Profitability & Efficiency
VCYT leads this category, winning 7 of 8 comparable metrics.
Profitability & Efficiency
VCYT delivers a 6.9% return on equity — every $100 of shareholder capital generates $7 in annual profit, vs $-15 for NTRA. VCYT carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to NTRA's 0.13x. On the Piotroski fundamental quality scale (0–9), VCYT scores 8/9 vs NTRA's 5/9, reflecting strong financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | +6.9% | -15.3% |
| ROA (TTM)Return on assets | +6.3% | -10.6% |
| ROICReturn on invested capital | +5.6% | -36.1% |
| ROCEReturn on capital employed | +5.8% | -18.3% |
| Piotroski ScoreFundamental quality 0–9 | 8 | 5 |
| Debt / EquityFinancial leverage | 0.03x | 0.13x |
| Net DebtTotal debt minus cash | -$323M | -$862M |
| Cash & Equiv.Liquid assets | $363M | $1.1B |
| Total DebtShort + long-term debt | $40M | $214M |
| Interest CoverageEBIT ÷ Interest expense | — | -25.21x |
Total Returns (Dividends Reinvested)
NTRA leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in NTRA five years ago would be worth $21,587 today (with dividends reinvested), compared to $9,191 for VCYT. Over the past 12 months, NTRA leads with a +37.3% total return vs VCYT's +32.2%. The 3-year compound annual growth rate (CAGR) favors NTRA at 60.6% vs VCYT's 21.7% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -3.8% | -3.9% |
| 1-Year ReturnPast 12 months | +32.2% | +37.3% |
| 3-Year ReturnCumulative with dividends | +80.1% | +314.0% |
| 5-Year ReturnCumulative with dividends | -8.1% | +115.9% |
| 10-Year ReturnCumulative with dividends | +638.4% | +2089.4% |
| CAGR (3Y)Annualised 3-year return | +21.7% | +60.6% |
Risk & Volatility
NTRA leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
NTRA is the less volatile stock with a 1.26 beta — it tends to amplify market swings less than VCYT's 1.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NTRA currently trades 85.7% from its 52-week high vs VCYT's 80.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.52x | 1.26x |
| 52-Week HighHighest price in past year | $50.71 | $256.36 |
| 52-Week LowLowest price in past year | $22.61 | $131.81 |
| % of 52W HighCurrent price vs 52-week peak | +80.4% | +85.7% |
| RSI (14)Momentum oscillator 0–100 | 73.3 | 57.1 |
| Avg Volume (50D)Average daily shares traded | 887K | 1.3M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates VCYT as "Buy" and NTRA as "Buy". Consensus price targets imply 19.4% upside for NTRA (target: $263) vs 9.2% for VCYT (target: $45).
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $44.50 | $262.50 |
| # AnalystsCovering analysts | 20 | 27 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
VCYT leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). NTRA leads in 2 (Total Returns, Risk & Volatility).
VCYT vs NTRA: Frequently Asked Questions
9 questions · data-driven answers · updated daily
01Is VCYT or NTRA a better buy right now?
For growth investors, Natera, Inc.
(NTRA) is the stronger pick with 35. 9% revenue growth year-over-year, versus 16. 0% for Veracyte, Inc. (VCYT). Veracyte, Inc. (VCYT) offers the better valuation at 49. 7x trailing P/E (24. 6x forward), making it the more compelling value choice. Analysts rate Veracyte, Inc. (VCYT) a "Buy" — based on 20 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — VCYT or NTRA?
Over the past 5 years, Natera, Inc.
(NTRA) delivered a total return of +115. 9%, compared to -8. 1% for Veracyte, Inc. (VCYT). Over 10 years, the gap is even starker: NTRA returned +20. 9% versus VCYT's +638. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — VCYT or NTRA?
By beta (market sensitivity over 5 years), Natera, Inc.
(NTRA) is the lower-risk stock at 1. 26β versus Veracyte, Inc. 's 1. 52β — meaning VCYT is approximately 21% more volatile than NTRA relative to the S&P 500. On balance sheet safety, Veracyte, Inc. (VCYT) carries a lower debt/equity ratio of 3% versus 13% for Natera, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — VCYT or NTRA?
By revenue growth (latest reported year), Natera, Inc.
(NTRA) is pulling ahead at 35. 9% versus 16. 0% for Veracyte, Inc. (VCYT). On earnings-per-share growth, the picture is similar: Veracyte, Inc. grew EPS 164. 5% year-over-year, compared to 0. 7% for Natera, Inc.. Over a 3-year CAGR, NTRA leads at 41. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — VCYT or NTRA?
Veracyte, Inc.
(VCYT) is the more profitable company, earning 12. 8% net margin versus -9. 0% for Natera, Inc. — meaning it keeps 12. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: VCYT leads at 14. 3% versus -13. 4% for NTRA. At the gross margin level — before operating expenses — VCYT leads at 69. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is VCYT or NTRA more undervalued right now?
Analyst consensus price targets imply the most upside for NTRA: 19.
4% to $262. 50.
07Which pays a better dividend — VCYT or NTRA?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is VCYT or NTRA better for a retirement portfolio?
For long-horizon retirement investors, Veracyte, Inc.
(VCYT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+638. 4% 10Y return). Both have compounded well over 10 years (VCYT: +638. 4%, NTRA: +20. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between VCYT and NTRA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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