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Stock Comparison

VCYT vs NTRA

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
VCYT
Veracyte, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.25B
5Y Perf.+63.4%
NTRA
Natera, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$31.16B
5Y Perf.+401.3%

VCYT vs NTRA — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
VCYT logoVCYT
NTRA logoNTRA
IndustryBiotechnologyMedical - Diagnostics & Research
Market Cap$3.25B$31.16B
Revenue (TTM)$542M$2.31B
Net Income (TTM)$88M$-208M
Gross Margin71.4%64.8%
Operating Margin12.2%-13.4%
Forward P/E24.6x
Total Debt$40M$214M
Cash & Equiv.$363M$1.08B

VCYT vs NTRALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

VCYT
NTRA
StockMay 20May 26Return
Veracyte, Inc. (VCYT)100163.4+63.4%
Natera, Inc. (NTRA)100501.3+401.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: VCYT vs NTRA

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: VCYT and NTRA are tied at the top with 3 categories each — the right choice depends on your priorities. Natera, Inc. is the stronger pick specifically for growth and revenue expansion and capital preservation and lower volatility. As sector peers, any of these can serve as alternatives in the same allocation.
VCYT
Veracyte, Inc.
The Defensive Pick

VCYT has the current edge in this matchup, primarily because of its strength in sleep-well-at-night.

  • Lower volatility, beta 1.52, Low D/E 3.0%, current ratio 8.15x
  • Better valuation composite
  • 16.2% margin vs NTRA's -9.0%
Best for: sleep-well-at-night
NTRA
Natera, Inc.
The Income Pick

NTRA is the clearest fit if your priority is income & stability and growth exposure.

  • beta 1.26
  • Rev growth 35.9%, EPS growth 0.7%, 3Y rev CAGR 41.1%
  • 20.9% 10Y total return vs VCYT's 6.4%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthNTRA logoNTRA35.9% revenue growth vs VCYT's 16.0%
ValueVCYT logoVCYTBetter valuation composite
Quality / MarginsVCYT logoVCYT16.2% margin vs NTRA's -9.0%
Stability / SafetyNTRA logoNTRABeta 1.26 vs VCYT's 1.52
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)NTRA logoNTRA+37.3% vs VCYT's +32.2%
Efficiency (ROA)VCYT logoVCYT6.3% ROA vs NTRA's -10.6%, ROIC 5.6% vs -36.1%

VCYT vs NTRA — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

VCYTVeracyte, Inc.
FY 2025
Testing
95.4%$493M
Product
2.8%$14M
Biopharmaceutical And Other
1.9%$10M
NTRANatera, Inc.
FY 2025
Product
99.6%$2.3B
Licensing and other
0.4%$10M

VCYT vs NTRA — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLVCYTLAGGINGNTRA

Income & Cash Flow (Last 12 Months)

VCYT leads this category, winning 5 of 6 comparable metrics.

NTRA is the larger business by revenue, generating $2.3B annually — 4.3x VCYT's $542M. VCYT is the more profitable business, keeping 16.2% of every revenue dollar as net income compared to NTRA's -9.0%. On growth, NTRA holds the edge at +39.8% YoY revenue growth, suggesting stronger near-term business momentum.

MetricVCYT logoVCYTVeracyte, Inc.NTRA logoNTRANatera, Inc.
RevenueTrailing 12 months$542M$2.3B
EBITDAEarnings before interest/tax$82M-$310M
Net IncomeAfter-tax profit$88M-$208M
Free Cash FlowCash after capex$155M$97M
Gross MarginGross profit ÷ Revenue+71.4%+64.8%
Operating MarginEBIT ÷ Revenue+12.2%-13.4%
Net MarginNet income ÷ Revenue+16.2%-9.0%
FCF MarginFCF ÷ Revenue+28.6%+4.2%
Rev. Growth (YoY)Latest quarter vs prior year+21.5%+39.8%
EPS Growth (YoY)Latest quarter vs prior year+3.0%+185.4%
VCYT leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

VCYT leads this category, winning 3 of 4 comparable metrics.
MetricVCYT logoVCYTVeracyte, Inc.NTRA logoNTRANatera, Inc.
Market CapShares × price$3.3B$31.2B
Enterprise ValueMkt cap + debt − cash$2.9B$30.3B
Trailing P/EPrice ÷ TTM EPS49.71x-144.62x
Forward P/EPrice ÷ next-FY EPS est.24.57x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple30.65x
Price / SalesMarket cap ÷ Revenue6.29x13.51x
Price / BookPrice ÷ Book value/share2.51x17.55x
Price / FCFMarket cap ÷ FCF25.68x285.53x
VCYT leads this category, winning 3 of 4 comparable metrics.

Profitability & Efficiency

VCYT leads this category, winning 7 of 8 comparable metrics.

VCYT delivers a 6.9% return on equity — every $100 of shareholder capital generates $7 in annual profit, vs $-15 for NTRA. VCYT carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to NTRA's 0.13x. On the Piotroski fundamental quality scale (0–9), VCYT scores 8/9 vs NTRA's 5/9, reflecting strong financial health.

MetricVCYT logoVCYTVeracyte, Inc.NTRA logoNTRANatera, Inc.
ROE (TTM)Return on equity+6.9%-15.3%
ROA (TTM)Return on assets+6.3%-10.6%
ROICReturn on invested capital+5.6%-36.1%
ROCEReturn on capital employed+5.8%-18.3%
Piotroski ScoreFundamental quality 0–985
Debt / EquityFinancial leverage0.03x0.13x
Net DebtTotal debt minus cash-$323M-$862M
Cash & Equiv.Liquid assets$363M$1.1B
Total DebtShort + long-term debt$40M$214M
Interest CoverageEBIT ÷ Interest expense-25.21x
VCYT leads this category, winning 7 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

NTRA leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in NTRA five years ago would be worth $21,587 today (with dividends reinvested), compared to $9,191 for VCYT. Over the past 12 months, NTRA leads with a +37.3% total return vs VCYT's +32.2%. The 3-year compound annual growth rate (CAGR) favors NTRA at 60.6% vs VCYT's 21.7% — a key indicator of consistent wealth creation.

MetricVCYT logoVCYTVeracyte, Inc.NTRA logoNTRANatera, Inc.
YTD ReturnYear-to-date-3.8%-3.9%
1-Year ReturnPast 12 months+32.2%+37.3%
3-Year ReturnCumulative with dividends+80.1%+314.0%
5-Year ReturnCumulative with dividends-8.1%+115.9%
10-Year ReturnCumulative with dividends+638.4%+2089.4%
CAGR (3Y)Annualised 3-year return+21.7%+60.6%
NTRA leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

NTRA leads this category, winning 2 of 2 comparable metrics.

NTRA is the less volatile stock with a 1.26 beta — it tends to amplify market swings less than VCYT's 1.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NTRA currently trades 85.7% from its 52-week high vs VCYT's 80.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricVCYT logoVCYTVeracyte, Inc.NTRA logoNTRANatera, Inc.
Beta (5Y)Sensitivity to S&P 5001.52x1.26x
52-Week HighHighest price in past year$50.71$256.36
52-Week LowLowest price in past year$22.61$131.81
% of 52W HighCurrent price vs 52-week peak+80.4%+85.7%
RSI (14)Momentum oscillator 0–10073.357.1
Avg Volume (50D)Average daily shares traded887K1.3M
NTRA leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates VCYT as "Buy" and NTRA as "Buy". Consensus price targets imply 19.4% upside for NTRA (target: $263) vs 9.2% for VCYT (target: $45).

MetricVCYT logoVCYTVeracyte, Inc.NTRA logoNTRANatera, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$44.50$262.50
# AnalystsCovering analysts2027
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

VCYT leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). NTRA leads in 2 (Total Returns, Risk & Volatility).

Best OverallVeracyte, Inc. (VCYT)Leads 3 of 6 categories
Loading custom metrics...

VCYT vs NTRA: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is VCYT or NTRA a better buy right now?

For growth investors, Natera, Inc.

(NTRA) is the stronger pick with 35. 9% revenue growth year-over-year, versus 16. 0% for Veracyte, Inc. (VCYT). Veracyte, Inc. (VCYT) offers the better valuation at 49. 7x trailing P/E (24. 6x forward), making it the more compelling value choice. Analysts rate Veracyte, Inc. (VCYT) a "Buy" — based on 20 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — VCYT or NTRA?

Over the past 5 years, Natera, Inc.

(NTRA) delivered a total return of +115. 9%, compared to -8. 1% for Veracyte, Inc. (VCYT). Over 10 years, the gap is even starker: NTRA returned +20. 9% versus VCYT's +638. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — VCYT or NTRA?

By beta (market sensitivity over 5 years), Natera, Inc.

(NTRA) is the lower-risk stock at 1. 26β versus Veracyte, Inc. 's 1. 52β — meaning VCYT is approximately 21% more volatile than NTRA relative to the S&P 500. On balance sheet safety, Veracyte, Inc. (VCYT) carries a lower debt/equity ratio of 3% versus 13% for Natera, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — VCYT or NTRA?

By revenue growth (latest reported year), Natera, Inc.

(NTRA) is pulling ahead at 35. 9% versus 16. 0% for Veracyte, Inc. (VCYT). On earnings-per-share growth, the picture is similar: Veracyte, Inc. grew EPS 164. 5% year-over-year, compared to 0. 7% for Natera, Inc.. Over a 3-year CAGR, NTRA leads at 41. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — VCYT or NTRA?

Veracyte, Inc.

(VCYT) is the more profitable company, earning 12. 8% net margin versus -9. 0% for Natera, Inc. — meaning it keeps 12. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: VCYT leads at 14. 3% versus -13. 4% for NTRA. At the gross margin level — before operating expenses — VCYT leads at 69. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is VCYT or NTRA more undervalued right now?

Analyst consensus price targets imply the most upside for NTRA: 19.

4% to $262. 50.

07

Which pays a better dividend — VCYT or NTRA?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is VCYT or NTRA better for a retirement portfolio?

For long-horizon retirement investors, Veracyte, Inc.

(VCYT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+638. 4% 10Y return). Both have compounded well over 10 years (VCYT: +638. 4%, NTRA: +20. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between VCYT and NTRA?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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VCYT

High-Growth Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 10%
  • Net Margin > 9%
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NTRA

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 19%
  • Gross Margin > 38%
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