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Stock Comparison

XGN vs NTRA

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
XGN
Exagen Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$71M
5Y Perf.-74.6%
NTRA
Natera, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$29.58B
5Y Perf.+401.3%

XGN vs NTRA — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
XGN logoXGN
NTRA logoNTRA
IndustryMedical - Diagnostics & ResearchMedical - Diagnostics & Research
Market Cap$71M$29.58B
Revenue (TTM)$67M$2.12B
Net Income (TTM)$-20M$-309M
Gross Margin58.3%63.7%
Operating Margin-21.1%-16.6%
Total Debt$5M$187M
Cash & Equiv.$32M$946M

XGN vs NTRALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

XGN
NTRA
StockMay 20May 26Return
Exagen Inc. (XGN)10025.4-74.6%
Natera, Inc. (NTRA)100501.3+401.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: XGN vs NTRA

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: NTRA leads in 5 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. As sector peers, any of these can serve as alternatives in the same allocation.
XGN
Exagen Inc.
The Specific-Use Pick

In this particular matchup, XGN is outpaced on most metrics by others in the set.

Best for: healthcare exposure
NTRA
Natera, Inc.
The Income Pick

NTRA carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 1.26
  • Rev growth 56.7%, EPS growth 59.5%, 3Y rev CAGR 39.5%
  • 21.5% 10Y total return vs XGN's -83.4%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthNTRA logoNTRA56.7% revenue growth vs XGN's 19.7%
Quality / MarginsNTRA logoNTRA-14.6% margin vs XGN's -30.0%
Stability / SafetyNTRA logoNTRABeta 1.26 vs XGN's 1.37, lower leverage
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)NTRA logoNTRA+38.3% vs XGN's -51.9%
Efficiency (ROA)NTRA logoNTRA-17.0% ROA vs XGN's -36.3%, ROIC -33.3% vs -18.5%

XGN vs NTRA — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

XGNExagen Inc.
FY 2025
Reportable Segment
100.0%$67M
NTRANatera, Inc.
FY 2025
Product
99.6%$2.3B
Licensing and other
0.4%$10M

XGN vs NTRA — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLNTRALAGGINGXGN

Income & Cash Flow (Last 12 Months)

NTRA leads this category, winning 5 of 6 comparable metrics.

NTRA is the larger business by revenue, generating $2.1B annually — 31.8x XGN's $67M. NTRA is the more profitable business, keeping -14.6% of every revenue dollar as net income compared to XGN's -30.0%. On growth, NTRA holds the edge at +34.7% YoY revenue growth, suggesting stronger near-term business momentum.

MetricXGN logoXGNExagen Inc.NTRA logoNTRANatera, Inc.
RevenueTrailing 12 months$67M$2.1B
EBITDAEarnings before interest/tax-$12M-$315M
Net IncomeAfter-tax profit-$20M-$309M
Free Cash FlowCash after capex-$14M$94M
Gross MarginGross profit ÷ Revenue+58.3%+63.7%
Operating MarginEBIT ÷ Revenue-21.1%-16.6%
Net MarginNet income ÷ Revenue-30.0%-14.6%
FCF MarginFCF ÷ Revenue-21.4%+4.4%
Rev. Growth (YoY)Latest quarter vs prior year+21.8%+34.7%
EPS Growth (YoY)Latest quarter vs prior year-5.0%-146.2%
NTRA leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

XGN leads this category, winning 2 of 3 comparable metrics.
MetricXGN logoXGNExagen Inc.NTRA logoNTRANatera, Inc.
Market CapShares × price$71M$29.6B
Enterprise ValueMkt cap + debt − cash$44M$28.8B
Trailing P/EPrice ÷ TTM EPS-3.32x-140.58x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue1.06x17.43x
Price / BookPrice ÷ Book value/share3.82x22.44x
Price / FCFMarket cap ÷ FCF427.23x
XGN leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

NTRA leads this category, winning 7 of 9 comparable metrics.

NTRA delivers a -24.7% return on equity — every $100 of shareholder capital generates $-25 in annual profit, vs $-127 for XGN. NTRA carries lower financial leverage with a 0.16x debt-to-equity ratio, signaling a more conservative balance sheet compared to XGN's 0.31x. On the Piotroski fundamental quality scale (0–9), NTRA scores 6/9 vs XGN's 3/9, reflecting solid financial health.

MetricXGN logoXGNExagen Inc.NTRA logoNTRANatera, Inc.
ROE (TTM)Return on equity-126.6%-24.7%
ROA (TTM)Return on assets-36.3%-17.0%
ROICReturn on invested capital-18.5%-33.3%
ROCEReturn on capital employed-37.5%-18.1%
Piotroski ScoreFundamental quality 0–936
Debt / EquityFinancial leverage0.31x0.16x
Net DebtTotal debt minus cash-$27M-$758M
Cash & Equiv.Liquid assets$32M$946M
Total DebtShort + long-term debt$5M$187M
Interest CoverageEBIT ÷ Interest expense-3.26x-69.90x
NTRA leads this category, winning 7 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NTRA leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in NTRA five years ago would be worth $22,333 today (with dividends reinvested), compared to $2,070 for XGN. Over the past 12 months, NTRA leads with a +38.3% total return vs XGN's -51.9%. The 3-year compound annual growth rate (CAGR) favors NTRA at 59.4% vs XGN's 3.3% — a key indicator of consistent wealth creation.

MetricXGN logoXGNExagen Inc.NTRA logoNTRANatera, Inc.
YTD ReturnYear-to-date-48.8%-6.0%
1-Year ReturnPast 12 months-51.9%+38.3%
3-Year ReturnCumulative with dividends+10.3%+305.1%
5-Year ReturnCumulative with dividends-79.3%+123.3%
10-Year ReturnCumulative with dividends-83.4%+2147.5%
CAGR (3Y)Annualised 3-year return+3.3%+59.4%
NTRA leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

NTRA leads this category, winning 2 of 2 comparable metrics.

NTRA is the less volatile stock with a 1.26 beta — it tends to amplify market swings less than XGN's 1.37 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NTRA currently trades 83.9% from its 52-week high vs XGN's 25.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricXGN logoXGNExagen Inc.NTRA logoNTRANatera, Inc.
Beta (5Y)Sensitivity to S&P 5001.37x1.26x
52-Week HighHighest price in past year$12.23$256.36
52-Week LowLowest price in past year$2.61$131.81
% of 52W HighCurrent price vs 52-week peak+25.3%+83.9%
RSI (14)Momentum oscillator 0–10055.951.9
Avg Volume (50D)Average daily shares traded251K1.3M
NTRA leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.
MetricXGN logoXGNExagen Inc.NTRA logoNTRANatera, Inc.
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target$262.50
# AnalystsCovering analysts27
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

NTRA leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). XGN leads in 1 (Valuation Metrics).

Best OverallNatera, Inc. (NTRA)Leads 4 of 6 categories
Loading custom metrics...

XGN vs NTRA: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is XGN or NTRA a better buy right now?

For growth investors, Natera, Inc.

(NTRA) is the stronger pick with 56. 7% revenue growth year-over-year, versus 19. 7% for Exagen Inc. (XGN). Analysts rate Natera, Inc. (NTRA) a "Buy" — based on 27 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — XGN or NTRA?

Over the past 5 years, Natera, Inc.

(NTRA) delivered a total return of +123. 3%, compared to -79. 3% for Exagen Inc. (XGN). Over 10 years, the gap is even starker: NTRA returned +20. 9% versus XGN's -84. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — XGN or NTRA?

By beta (market sensitivity over 5 years), Natera, Inc.

(NTRA) is the lower-risk stock at 1. 26β versus Exagen Inc. 's 1. 37β — meaning XGN is approximately 9% more volatile than NTRA relative to the S&P 500. On balance sheet safety, Natera, Inc. (NTRA) carries a lower debt/equity ratio of 16% versus 31% for Exagen Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — XGN or NTRA?

By revenue growth (latest reported year), Natera, Inc.

(NTRA) is pulling ahead at 56. 7% versus 19. 7% for Exagen Inc. (XGN). On earnings-per-share growth, the picture is similar: Natera, Inc. grew EPS 59. 5% year-over-year, compared to -12. 0% for Exagen Inc.. Over a 3-year CAGR, NTRA leads at 39. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — XGN or NTRA?

Natera, Inc.

(NTRA) is the more profitable company, earning -11. 2% net margin versus -30. 0% for Exagen Inc. — meaning it keeps -11. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NTRA leads at -13. 1% versus -21. 1% for XGN. At the gross margin level — before operating expenses — NTRA leads at 60. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — XGN or NTRA?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is XGN or NTRA better for a retirement portfolio?

For long-horizon retirement investors, Natera, Inc.

(NTRA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 26)). Both have compounded well over 10 years (NTRA: +20. 9%, XGN: -84. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between XGN and NTRA?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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XGN

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 10%
  • Gross Margin > 34%
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High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 17%
  • Gross Margin > 38%
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