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Stock Comparison

A vs BRKR vs WAT vs TMO

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
A
Agilent Technologies, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$33.31B
5Y Perf.+74.9%
BRKR
Bruker Corporation

Medical - Devices

HealthcareNASDAQ • US
Market Cap$6.44B
5Y Perf.-2.3%
WAT
Waters Corporation

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$22.78B
5Y Perf.+2.5%
TMO
Thermo Fisher Scientific Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$175.76B
5Y Perf.+35.4%

A vs BRKR vs WAT vs TMO — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
A logoA
BRKR logoBRKR
WAT logoWAT
TMO logoTMO
IndustryMedical - Diagnostics & ResearchMedical - DevicesMedical - Diagnostics & ResearchMedical - Diagnostics & Research
Market Cap$33.31B$6.44B$22.78B$175.76B
Revenue (TTM)$7.07B$3.46B$3.77B$45.20B
Net Income (TTM)$1.29B$-26M$449M$6.86B
Gross Margin38.8%45.3%55.0%39.4%
Operating Margin20.6%4.9%17.1%17.8%
Forward P/E19.7x20.0x24.3x19.0x
Total Debt$3.35B$2.04B$1.41B$40.85B
Cash & Equiv.$1.79B$299M$588M$9.86B

A vs BRKR vs WAT vs TMOLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

A
BRKR
WAT
TMO
StockMay 20May 26Return
Agilent Technologie… (A)100133.5+33.5%
Bruker Corporation (BRKR)10097.7-2.3%
Waters Corporation (WAT)100174.9+74.9%
Thermo Fisher Scien… (TMO)100135.4+35.4%

Price return only. Dividends and distributions are not included.

Quick Verdict: A vs BRKR vs WAT vs TMO

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: A leads in 3 of 7 categories, making it the strongest pick for profitability and margin quality and dividend income and shareholder returns. Waters Corporation is the stronger pick specifically for growth and revenue expansion and capital preservation and lower volatility. TMO also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
A
Agilent Technologies, Inc.
The Income Pick

A carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.

  • Dividend streak 10 yrs, beta 1.23, yield 0.8%
  • Lower volatility, beta 1.23, Low D/E 49.8%, current ratio 1.96x
  • PEG 1.34 vs TMO's 9.02
  • Beta 1.23, yield 0.8%, current ratio 1.96x
Best for: income & stability and sleep-well-at-night
BRKR
Bruker Corporation
The Secondary Option

BRKR lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
WAT
Waters Corporation
The Growth Play

WAT is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 7.0%, EPS growth 0.5%, 3Y rev CAGR 2.1%
  • 7.0% revenue growth vs BRKR's 2.1%
  • Beta 1.07 vs BRKR's 1.59, lower leverage
Best for: growth exposure
TMO
Thermo Fisher Scientific Inc.
The Long-Run Compounder

TMO is the clearest fit if your priority is long-term compounding.

  • 229.1% 10Y total return vs WAT's 163.2%
  • Lower P/E (19.0x vs 24.3x)
  • +16.6% vs WAT's +3.1%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthWAT logoWAT7.0% revenue growth vs BRKR's 2.1%
ValueTMO logoTMOLower P/E (19.0x vs 24.3x)
Quality / MarginsA logoA18.3% margin vs BRKR's -0.8%
Stability / SafetyWAT logoWATBeta 1.07 vs BRKR's 1.59, lower leverage
DividendsA logoA0.8% yield, 10-year raise streak, vs TMO's 0.4%, (1 stock pays no dividend)
Momentum (1Y)TMO logoTMO+16.6% vs WAT's +3.1%
Efficiency (ROA)A logoA10.1% ROA vs BRKR's -0.4%, ROIC 13.5% vs 4.4%

A vs BRKR vs WAT vs TMO — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

AAgilent Technologies, Inc.
FY 2025
Agilent CrossLab
41.9%$2.9B
Life Sciences and Applied Markets
39.2%$2.7B
Applied Markets
18.9%$1.3B
BRKRBruker Corporation
FY 2025
Product
80.5%$2.8B
Product and Service, Other
19.5%$670M
WATWaters Corporation
FY 2025
Waters Instrument Systems
34.8%$1.1B
Waters Service
34.1%$1.1B
Chemistry Consumables
19.9%$631M
Ta Instrument Systems
7.7%$244M
Ta Service
3.4%$108M
TMOThermo Fisher Scientific Inc.
FY 2025
Consumables
41.9%$18.7B
Service
41.7%$18.6B
Instruments
16.4%$7.3B

A vs BRKR vs WAT vs TMO — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLWATLAGGINGTMO

Income & Cash Flow (Last 12 Months)

Evenly matched — A and WAT and TMO each lead in 2 of 6 comparable metrics.

TMO is the larger business by revenue, generating $45.2B annually — 13.1x BRKR's $3.5B. A is the more profitable business, keeping 18.3% of every revenue dollar as net income compared to BRKR's -0.8%. On growth, WAT holds the edge at +91.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricA logoAAgilent Technolog…BRKR logoBRKRBruker CorporationWAT logoWATWaters CorporationTMO logoTMOThermo Fisher Sci…
RevenueTrailing 12 months$7.1B$3.5B$3.8B$45.2B
EBITDAEarnings before interest/tax$1.7B$339M$953M$10.5B
Net IncomeAfter-tax profit$1.3B-$26M$449M$6.9B
Free Cash FlowCash after capex$993M$51M$264M$6.7B
Gross MarginGross profit ÷ Revenue+38.8%+45.3%+55.0%+39.4%
Operating MarginEBIT ÷ Revenue+20.6%+4.9%+17.1%+17.8%
Net MarginNet income ÷ Revenue+18.3%-0.8%+11.9%+15.2%
FCF MarginFCF ÷ Revenue+14.1%+1.5%+7.0%+14.9%
Rev. Growth (YoY)Latest quarter vs prior year+7.0%+2.7%+91.5%+6.2%
EPS Growth (YoY)Latest quarter vs prior year-3.6%-81.8%-142.9%+11.3%
Evenly matched — A and WAT and TMO each lead in 2 of 6 comparable metrics.

Valuation Metrics

BRKR leads this category, winning 4 of 7 comparable metrics.

At 25.8x trailing earnings, A trades at a 21% valuation discount to WAT's 32.5x P/E. Adjusting for growth (PEG ratio), A offers better value at 1.75x vs TMO's 12.62x — a lower PEG means you pay less per unit of expected earnings growth.

MetricA logoAAgilent Technolog…BRKR logoBRKRBruker CorporationWAT logoWATWaters CorporationTMO logoTMOThermo Fisher Sci…
Market CapShares × price$33.3B$6.4B$22.8B$175.8B
Enterprise ValueMkt cap + debt − cash$34.9B$8.2B$23.6B$206.8B
Trailing P/EPrice ÷ TTM EPS25.75x-282.00x32.48x26.66x
Forward P/EPrice ÷ next-FY EPS est.19.71x20.01x24.30x19.04x
PEG RatioP/E ÷ EPS growth rate1.75x6.27x12.62x
EV / EBITDAEnterprise value multiple19.74x17.93x21.47x18.99x
Price / SalesMarket cap ÷ Revenue4.79x1.87x7.20x3.94x
Price / BookPrice ÷ Book value/share4.96x2.56x8.15x3.33x
Price / FCFMarket cap ÷ FCF28.92x148.71x42.21x27.93x
BRKR leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

Evenly matched — A and WAT each lead in 4 of 9 comparable metrics.

A delivers a 18.7% return on equity — every $100 of shareholder capital generates $19 in annual profit, vs $-1 for BRKR. A carries lower financial leverage with a 0.50x debt-to-equity ratio, signaling a more conservative balance sheet compared to BRKR's 0.81x. On the Piotroski fundamental quality scale (0–9), TMO scores 6/9 vs WAT's 4/9, reflecting solid financial health.

MetricA logoAAgilent Technolog…BRKR logoBRKRBruker CorporationWAT logoWATWaters CorporationTMO logoTMOThermo Fisher Sci…
ROE (TTM)Return on equity+18.7%-1.1%+8.0%+13.2%
ROA (TTM)Return on assets+10.1%-0.4%+4.6%+6.4%
ROICReturn on invested capital+13.5%+4.4%+20.3%+7.5%
ROCEReturn on capital employed+14.5%+5.0%+18.5%+9.1%
Piotroski ScoreFundamental quality 0–95446
Debt / EquityFinancial leverage0.50x0.81x0.55x0.76x
Net DebtTotal debt minus cash$1.6B$1.7B$820M$31.0B
Cash & Equiv.Liquid assets$1.8B$299M$588M$9.9B
Total DebtShort + long-term debt$3.4B$2.0B$1.4B$40.9B
Interest CoverageEBIT ÷ Interest expense19.53x0.75x6.72x5.89x
Evenly matched — A and WAT each lead in 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

WAT leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in WAT five years ago would be worth $11,311 today (with dividends reinvested), compared to $6,345 for BRKR. Over the past 12 months, TMO leads with a +16.6% total return vs WAT's +3.1%. The 3-year compound annual growth rate (CAGR) favors WAT at 5.6% vs BRKR's -17.8% — a key indicator of consistent wealth creation.

MetricA logoAAgilent Technolog…BRKR logoBRKRBruker CorporationWAT logoWATWaters CorporationTMO logoTMOThermo Fisher Sci…
YTD ReturnYear-to-date-14.3%-12.0%-8.5%-20.1%
1-Year ReturnPast 12 months+12.8%+7.7%+3.1%+16.6%
3-Year ReturnCumulative with dividends-9.0%-44.4%+17.9%-11.9%
5-Year ReturnCumulative with dividends-7.7%-36.6%+13.1%+2.1%
10-Year ReturnCumulative with dividends+202.6%+59.6%+163.2%+229.1%
CAGR (3Y)Annualised 3-year return-3.1%-17.8%+5.6%-4.2%
WAT leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

WAT leads this category, winning 2 of 2 comparable metrics.

WAT is the less volatile stock with a 1.07 beta — it tends to amplify market swings less than BRKR's 1.59 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. WAT currently trades 84.4% from its 52-week high vs A's 73.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricA logoAAgilent Technolog…BRKR logoBRKRBruker CorporationWAT logoWATWaters CorporationTMO logoTMOThermo Fisher Sci…
Beta (5Y)Sensitivity to S&P 5001.23x1.59x1.07x1.10x
52-Week HighHighest price in past year$160.27$56.22$414.15$643.99
52-Week LowLowest price in past year$104.36$28.53$275.05$385.46
% of 52W HighCurrent price vs 52-week peak+73.4%+75.2%+84.4%+73.4%
RSI (14)Momentum oscillator 0–10052.252.662.739.8
Avg Volume (50D)Average daily shares traded2.0M1.9M989K1.9M
WAT leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

A leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: A as "Buy", BRKR as "Buy", WAT as "Hold", TMO as "Buy". Consensus price targets imply 41.0% upside for A (target: $166) vs 15.2% for WAT (target: $403). For income investors, A offers the higher dividend yield at 0.84% vs BRKR's 0.36%.

MetricA logoAAgilent Technolog…BRKR logoBRKRBruker CorporationWAT logoWATWaters CorporationTMO logoTMOThermo Fisher Sci…
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuy
Price TargetConsensus 12-month target$166.00$52.13$402.57$654.67
# AnalystsCovering analysts38323442
Dividend YieldAnnual dividend ÷ price+0.8%+0.4%+0.4%
Dividend StreakConsecutive years of raises10018
Dividend / ShareAnnual DPS$0.99$0.15$1.69
Buyback YieldShare repurchases ÷ mkt cap+1.3%+0.2%+0.1%+1.7%
A leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

WAT leads in 2 of 6 categories (Total Returns, Risk & Volatility). BRKR leads in 1 (Valuation Metrics). 2 tied.

Best OverallWaters Corporation (WAT)Leads 2 of 6 categories
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A vs BRKR vs WAT vs TMO: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is A or BRKR or WAT or TMO a better buy right now?

For growth investors, Waters Corporation (WAT) is the stronger pick with 7.

0% revenue growth year-over-year, versus 2. 1% for Bruker Corporation (BRKR). Agilent Technologies, Inc. (A) offers the better valuation at 25. 8x trailing P/E (19. 7x forward), making it the more compelling value choice. Analysts rate Agilent Technologies, Inc. (A) a "Buy" — based on 38 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — A or BRKR or WAT or TMO?

On trailing P/E, Agilent Technologies, Inc.

(A) is the cheapest at 25. 8x versus Waters Corporation at 32. 5x. On forward P/E, Thermo Fisher Scientific Inc. is actually cheaper at 19. 0x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Agilent Technologies, Inc. wins at 1. 34x versus Thermo Fisher Scientific Inc. 's 9. 02x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — A or BRKR or WAT or TMO?

Over the past 5 years, Waters Corporation (WAT) delivered a total return of +13.

1%, compared to -36. 6% for Bruker Corporation (BRKR). Over 10 years, the gap is even starker: TMO returned +229. 1% versus BRKR's +59. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — A or BRKR or WAT or TMO?

By beta (market sensitivity over 5 years), Waters Corporation (WAT) is the lower-risk stock at 1.

07β versus Bruker Corporation's 1. 59β — meaning BRKR is approximately 48% more volatile than WAT relative to the S&P 500. On balance sheet safety, Agilent Technologies, Inc. (A) carries a lower debt/equity ratio of 50% versus 81% for Bruker Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — A or BRKR or WAT or TMO?

By revenue growth (latest reported year), Waters Corporation (WAT) is pulling ahead at 7.

0% versus 2. 1% for Bruker Corporation (BRKR). On earnings-per-share growth, the picture is similar: Thermo Fisher Scientific Inc. grew EPS 7. 3% year-over-year, compared to -119. 7% for Bruker Corporation. Over a 3-year CAGR, BRKR leads at 10. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — A or BRKR or WAT or TMO?

Waters Corporation (WAT) is the more profitable company, earning 20.

3% net margin versus -0. 3% for Bruker Corporation — meaning it keeps 20. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: WAT leads at 28. 2% versus 6. 9% for BRKR. At the gross margin level — before operating expenses — WAT leads at 57. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is A or BRKR or WAT or TMO more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Agilent Technologies, Inc. (A) is the more undervalued stock at a PEG of 1. 34x versus Thermo Fisher Scientific Inc. 's 9. 02x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Thermo Fisher Scientific Inc. (TMO) trades at 19. 0x forward P/E versus 24. 3x for Waters Corporation — 5. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for A: 41. 0% to $166. 00.

08

Which pays a better dividend — A or BRKR or WAT or TMO?

In this comparison, A (0.

8% yield), TMO (0. 4% yield), BRKR (0. 4% yield) pay a dividend. WAT does not pay a meaningful dividend and should not be held primarily for income.

09

Is A or BRKR or WAT or TMO better for a retirement portfolio?

For long-horizon retirement investors, Agilent Technologies, Inc.

(A) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 23), 0. 8% yield, +202. 6% 10Y return). Bruker Corporation (BRKR) carries a higher beta of 1. 59 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (A: +202. 6%, BRKR: +59. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between A and BRKR and WAT and TMO?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

A pays a dividend while BRKR, WAT, TMO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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