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Stock Comparison

ABUS vs HBIO

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ABUS
Arbutus Biopharma Corporation

Biotechnology

HealthcareNASDAQ • US
Market Cap$838M
5Y Perf.+100.5%
HBIO
Harvard Bioscience, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$304M
5Y Perf.-74.3%

ABUS vs HBIO — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ABUS logoABUS
HBIO logoHBIO
IndustryBiotechnologyMedical - Instruments & Supplies
Market Cap$838M$304M
Revenue (TTM)$14M$87M
Net Income (TTM)$-34M$-57M
Gross Margin2.8%53.0%
Operating Margin-271.0%-0.7%
Total Debt$746K$36M
Cash & Equiv.$18M$9M

ABUS vs HBIOLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ABUS
HBIO
StockMay 20May 26Return
Arbutus Biopharma C… (ABUS)100200.5+100.5%
Harvard Bioscience,… (HBIO)10025.7-74.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: ABUS vs HBIO

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ABUS leads in 3 of 6 categories, making it the strongest pick for growth and revenue expansion and capital preservation and lower volatility. Harvard Bioscience, Inc. is the stronger pick specifically for profitability and margin quality and recent price momentum and sentiment. As sector peers, any of these can serve as alternatives in the same allocation.
ABUS
Arbutus Biopharma Corporation
The Income Pick

ABUS carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 0 yrs, beta 1.39
  • Rev growth 128.2%, EPS growth 55.3%, 3Y rev CAGR -28.8%
  • 1.4% 10Y total return vs HBIO's -76.2%
Best for: income & stability and growth exposure
HBIO
Harvard Bioscience, Inc.
The Quality Compounder

HBIO is the clearest fit if your priority is quality and momentum.

  • -65.5% margin vs ABUS's -237.9%
  • +126.3% vs ABUS's +32.2%
Best for: quality and momentum
See the full category breakdown
CategoryWinnerWhy
GrowthABUS logoABUS128.2% revenue growth vs HBIO's -8.1%
Quality / MarginsHBIO logoHBIO-65.5% margin vs ABUS's -237.9%
Stability / SafetyABUS logoABUSBeta 1.39 vs HBIO's 2.03, lower leverage
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)HBIO logoHBIO+126.3% vs ABUS's +32.2%
Efficiency (ROA)ABUS logoABUS-32.5% ROA vs HBIO's -71.3%, ROIC -47.1% vs -0.7%

ABUS vs HBIO — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ABUSArbutus Biopharma Corporation
FY 2025
License
82.1%$10M
Non-Cash Royalty
11.7%$1M
Service, Other
6.3%$800,000
HBIOHarvard Bioscience, Inc.
FY 2025
Instruments, Equipment, Software, and Accessories
90.4%$78M
Service, Maintenance, and Warranty Contracts
9.6%$8M

ABUS vs HBIO — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLABUSLAGGINGHBIO

Income & Cash Flow (Last 12 Months)

HBIO leads this category, winning 5 of 5 comparable metrics.

HBIO is the larger business by revenue, generating $87M annually — 6.1x ABUS's $14M. Profitability is closely matched — net margins range from -65.5% (HBIO) to -2.4% (ABUS). On growth, HBIO holds the edge at -3.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricABUS logoABUSArbutus Biopharma…HBIO logoHBIOHarvard Bioscienc…
RevenueTrailing 12 months$14M$87M
EBITDAEarnings before interest/tax-$37M$5M
Net IncomeAfter-tax profit-$34M-$57M
Free Cash FlowCash after capex-$40M$5M
Gross MarginGross profit ÷ Revenue+2.8%+53.0%
Operating MarginEBIT ÷ Revenue-2.7%-0.7%
Net MarginNet income ÷ Revenue-2.4%-65.5%
FCF MarginFCF ÷ Revenue-2.8%+5.9%
Rev. Growth (YoY)Latest quarter vs prior year-33.2%-3.3%
EPS Growth (YoY)Latest quarter vs prior year+80.6%
HBIO leads this category, winning 5 of 5 comparable metrics.

Valuation Metrics

ABUS leads this category, winning 2 of 3 comparable metrics.
MetricABUS logoABUSArbutus Biopharma…HBIO logoHBIOHarvard Bioscienc…
Market CapShares × price$838M$304M
Enterprise ValueMkt cap + debt − cash$820M$331M
Trailing P/EPrice ÷ TTM EPS-25.59x-5.30x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple62.25x
Price / SalesMarket cap ÷ Revenue59.47x3.51x
Price / BookPrice ÷ Book value/share10.88x21.95x
Price / FCFMarket cap ÷ FCF54.08x
ABUS leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

ABUS leads this category, winning 5 of 8 comparable metrics.

ABUS delivers a -42.4% return on equity — every $100 of shareholder capital generates $-42 in annual profit, vs $-4 for HBIO. ABUS carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to HBIO's 2.61x.

MetricABUS logoABUSArbutus Biopharma…HBIO logoHBIOHarvard Bioscienc…
ROE (TTM)Return on equity-42.4%-3.9%
ROA (TTM)Return on assets-32.5%-71.3%
ROICReturn on invested capital-47.1%-0.7%
ROCEReturn on capital employed-37.3%-1.0%
Piotroski ScoreFundamental quality 0–944
Debt / EquityFinancial leverage0.01x2.61x
Net DebtTotal debt minus cash-$17M$27M
Cash & Equiv.Liquid assets$18M$9M
Total DebtShort + long-term debt$746,000$36M
Interest CoverageEBIT ÷ Interest expense-129.55x-0.13x
ABUS leads this category, winning 5 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

ABUS leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in ABUS five years ago would be worth $15,480 today (with dividends reinvested), compared to $925 for HBIO. Over the past 12 months, HBIO leads with a +126.3% total return vs ABUS's +32.2%. The 3-year compound annual growth rate (CAGR) favors ABUS at 18.6% vs HBIO's -51.4% — a key indicator of consistent wealth creation.

MetricABUS logoABUSArbutus Biopharma…HBIO logoHBIOHarvard Bioscienc…
YTD ReturnYear-to-date-8.8%+4.1%
1-Year ReturnPast 12 months+32.2%+126.3%
3-Year ReturnCumulative with dividends+66.7%-88.5%
5-Year ReturnCumulative with dividends+54.8%-90.7%
10-Year ReturnCumulative with dividends+1.4%-76.2%
CAGR (3Y)Annualised 3-year return+18.6%-51.4%
ABUS leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

ABUS leads this category, winning 2 of 2 comparable metrics.

ABUS is the less volatile stock with a 1.39 beta — it tends to amplify market swings less than HBIO's 2.03 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ABUS currently trades 85.3% from its 52-week high vs HBIO's 71.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricABUS logoABUSArbutus Biopharma…HBIO logoHBIOHarvard Bioscienc…
Beta (5Y)Sensitivity to S&P 5001.39x2.03x
52-Week HighHighest price in past year$5.10$9.46
52-Week LowLowest price in past year$2.94$0.59
% of 52W HighCurrent price vs 52-week peak+85.3%+71.8%
RSI (14)Momentum oscillator 0–10052.665.8
Avg Volume (50D)Average daily shares traded2.3M59K
ABUS leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates ABUS as "Buy" and HBIO as "Buy". Consensus price targets imply 95.4% upside for ABUS (target: $9) vs -11.6% for HBIO (target: $6).

MetricABUS logoABUSArbutus Biopharma…HBIO logoHBIOHarvard Bioscienc…
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$8.50$6.00
# AnalystsCovering analysts105
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises00
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

ABUS leads in 4 of 6 categories (Valuation Metrics, Profitability & Efficiency). HBIO leads in 1 (Income & Cash Flow).

Best OverallArbutus Biopharma Corporati… (ABUS)Leads 4 of 6 categories
Loading custom metrics...

ABUS vs HBIO: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is ABUS or HBIO a better buy right now?

For growth investors, Arbutus Biopharma Corporation (ABUS) is the stronger pick with 128.

2% revenue growth year-over-year, versus -8. 1% for Harvard Bioscience, Inc. (HBIO). Analysts rate Arbutus Biopharma Corporation (ABUS) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — ABUS or HBIO?

Over the past 5 years, Arbutus Biopharma Corporation (ABUS) delivered a total return of +54.

8%, compared to -90. 7% for Harvard Bioscience, Inc. (HBIO). Over 10 years, the gap is even starker: ABUS returned +1. 4% versus HBIO's -76. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — ABUS or HBIO?

By beta (market sensitivity over 5 years), Arbutus Biopharma Corporation (ABUS) is the lower-risk stock at 1.

39β versus Harvard Bioscience, Inc. 's 2. 03β — meaning HBIO is approximately 47% more volatile than ABUS relative to the S&P 500. On balance sheet safety, Arbutus Biopharma Corporation (ABUS) carries a lower debt/equity ratio of 1% versus 3% for Harvard Bioscience, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — ABUS or HBIO?

By revenue growth (latest reported year), Arbutus Biopharma Corporation (ABUS) is pulling ahead at 128.

2% versus -8. 1% for Harvard Bioscience, Inc. (HBIO). On earnings-per-share growth, the picture is similar: Arbutus Biopharma Corporation grew EPS 55. 3% year-over-year, compared to -357. 1% for Harvard Bioscience, Inc.. Over a 3-year CAGR, HBIO leads at -8. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — ABUS or HBIO?

Harvard Bioscience, Inc.

(HBIO) is the more profitable company, earning -65. 5% net margin versus -237. 9% for Arbutus Biopharma Corporation — meaning it keeps -65. 5% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HBIO leads at -0. 7% versus -271. 0% for ABUS. At the gross margin level — before operating expenses — HBIO leads at 53. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — ABUS or HBIO?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is ABUS or HBIO better for a retirement portfolio?

For long-horizon retirement investors, Arbutus Biopharma Corporation (ABUS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding.

Harvard Bioscience, Inc. (HBIO) carries a higher beta of 2. 03 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ABUS: +1. 4%, HBIO: -76. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between ABUS and HBIO?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ABUS is a small-cap high-growth stock; HBIO is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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ABUS

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  • Sector: Healthcare
  • Market Cap > $100B
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HBIO

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 31%
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Revenue Growth>
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(ABUS: -33.2% · HBIO: -3.3%)

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