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Stock Comparison

ABUS vs HBIO vs ITRN vs REPL

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ABUS
Arbutus Biopharma Corporation

Biotechnology

HealthcareNASDAQ • US
Market Cap$838M
5Y Perf.+100.5%
HBIO
Harvard Bioscience, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$304M
5Y Perf.-74.3%
ITRN
Ituran Location and Control Ltd.

Communication Equipment

TechnologyNASDAQ • IL
Market Cap$1.38B
5Y Perf.+244.5%
REPL
Replimune Group, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$266M
5Y Perf.-82.2%

ABUS vs HBIO vs ITRN vs REPL — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ABUS logoABUS
HBIO logoHBIO
ITRN logoITRN
REPL logoREPL
IndustryBiotechnologyMedical - Instruments & SuppliesCommunication EquipmentBiotechnology
Market Cap$838M$304M$1.38B$266M
Revenue (TTM)$14M$87M$359M$0.00
Net Income (TTM)$-34M$-57M$58M$-315M
Gross Margin2.8%53.0%49.7%
Operating Margin-271.0%-0.7%21.4%
Forward P/E17.8x
Total Debt$746K$36M$5M$76M
Cash & Equiv.$18M$9M$108M$111M

ABUS vs HBIO vs ITRN vs REPLLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ABUS
HBIO
ITRN
REPL
StockMay 20May 26Return
Arbutus Biopharma C… (ABUS)100200.5+100.5%
Harvard Bioscience,… (HBIO)10025.7-74.3%
Ituran Location and… (ITRN)100344.5+244.5%
Replimune Group, In… (REPL)10017.8-82.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: ABUS vs HBIO vs ITRN vs REPL

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ITRN leads in 4 of 7 categories, making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Arbutus Biopharma Corporation is the stronger pick specifically for growth and revenue expansion. HBIO and REPL also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
ABUS
Arbutus Biopharma Corporation
The Growth Play

ABUS is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 128.2%, EPS growth 55.3%, 3Y rev CAGR -28.8%
  • 128.2% revenue growth vs REPL's -39.7%
Best for: growth exposure
HBIO
Harvard Bioscience, Inc.
The Momentum Pick

HBIO is the clearest fit if your priority is momentum.

  • +126.3% vs REPL's -53.4%
Best for: momentum
ITRN
Ituran Location and Control Ltd.
The Income Pick

ITRN carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • Dividend streak 3 yrs, beta 1.18, yield 3.2%
  • 233.6% 10Y total return vs ABUS's 1.4%
  • Better valuation composite
  • 16.1% margin vs ABUS's -237.9%
Best for: income & stability and long-term compounding
REPL
Replimune Group, Inc.
The Defensive Pick

REPL is the clearest fit if your priority is sleep-well-at-night and defensive.

  • Lower volatility, beta 0.83, Low D/E 18.3%, current ratio 7.95x
  • Beta 0.83, current ratio 7.95x
  • Beta 0.83 vs HBIO's 2.03, lower leverage
Best for: sleep-well-at-night and defensive
See the full category breakdown
CategoryWinnerWhy
GrowthABUS logoABUS128.2% revenue growth vs REPL's -39.7%
ValueITRN logoITRNBetter valuation composite
Quality / MarginsITRN logoITRN16.1% margin vs ABUS's -237.9%
Stability / SafetyREPL logoREPLBeta 0.83 vs HBIO's 2.03, lower leverage
DividendsITRN logoITRN3.2% yield; 3-year raise streak; the other 3 pay no meaningful dividend
Momentum (1Y)HBIO logoHBIO+126.3% vs REPL's -53.4%
Efficiency (ROA)ITRN logoITRN15.8% ROA vs REPL's -94.4%, ROIC 47.2% vs -51.9%

ABUS vs HBIO vs ITRN vs REPL — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ABUSArbutus Biopharma Corporation
FY 2025
License
82.1%$10M
Non-Cash Royalty
11.7%$1M
Service, Other
6.3%$800,000
HBIOHarvard Bioscience, Inc.
FY 2025
Instruments, Equipment, Software, and Accessories
90.4%$78M
Service, Maintenance, and Warranty Contracts
9.6%$8M
ITRNIturan Location and Control Ltd.
FY 2021
Telematics Services
70.0%$190M
Telematics Products
30.0%$81M
REPLReplimune Group, Inc.

Segment breakdown not available.

ABUS vs HBIO vs ITRN vs REPL — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLITRNLAGGINGREPL

Income & Cash Flow (Last 12 Months)

ITRN leads this category, winning 4 of 6 comparable metrics.

ITRN and REPL operate at a comparable scale, with $359M and $0 in trailing revenue. ITRN is the more profitable business, keeping 16.1% of every revenue dollar as net income compared to ABUS's -2.4%. On growth, ITRN holds the edge at +12.8% YoY revenue growth, suggesting stronger near-term business momentum.

MetricABUS logoABUSArbutus Biopharma…HBIO logoHBIOHarvard Bioscienc…ITRN logoITRNIturan Location a…REPL logoREPLReplimune Group, …
RevenueTrailing 12 months$14M$87M$359M$0
EBITDAEarnings before interest/tax-$37M$5M$96M-$323M
Net IncomeAfter-tax profit-$34M-$57M$58M-$315M
Free Cash FlowCash after capex-$40M$5M$71M-$283M
Gross MarginGross profit ÷ Revenue+2.8%+53.0%+49.7%
Operating MarginEBIT ÷ Revenue-2.7%-0.7%+21.4%
Net MarginNet income ÷ Revenue-2.4%-65.5%+16.1%
FCF MarginFCF ÷ Revenue-2.8%+5.9%+19.7%
Rev. Growth (YoY)Latest quarter vs prior year-33.2%-3.3%+12.8%
EPS Growth (YoY)Latest quarter vs prior year+80.6%+10.0%+2.5%
ITRN leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

ITRN leads this category, winning 2 of 5 comparable metrics.

On an enterprise value basis, ITRN's 13.3x EV/EBITDA is more attractive than HBIO's 62.2x.

MetricABUS logoABUSArbutus Biopharma…HBIO logoHBIOHarvard Bioscienc…ITRN logoITRNIturan Location a…REPL logoREPLReplimune Group, …
Market CapShares × price$838M$304M$1.4B$266M
Enterprise ValueMkt cap + debt − cash$820M$331M$1.3B$231M
Trailing P/EPrice ÷ TTM EPS-25.59x-5.30x20.19x-1.09x
Forward P/EPrice ÷ next-FY EPS est.17.84x
PEG RatioP/E ÷ EPS growth rate0.66x
EV / EBITDAEnterprise value multiple62.25x13.33x
Price / SalesMarket cap ÷ Revenue59.47x3.51x3.85x
Price / BookPrice ÷ Book value/share10.88x21.95x5.22x0.65x
Price / FCFMarket cap ÷ FCF54.08x20.72x
ITRN leads this category, winning 2 of 5 comparable metrics.

Profitability & Efficiency

ITRN leads this category, winning 7 of 9 comparable metrics.

ITRN delivers a 27.3% return on equity — every $100 of shareholder capital generates $27 in annual profit, vs $-4 for HBIO. ABUS carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to HBIO's 2.61x. On the Piotroski fundamental quality scale (0–9), ITRN scores 7/9 vs REPL's 2/9, reflecting strong financial health.

MetricABUS logoABUSArbutus Biopharma…HBIO logoHBIOHarvard Bioscienc…ITRN logoITRNIturan Location a…REPL logoREPLReplimune Group, …
ROE (TTM)Return on equity-42.4%-3.9%+27.3%-149.5%
ROA (TTM)Return on assets-32.5%-71.3%+15.8%-94.4%
ROICReturn on invested capital-47.1%-0.7%+47.2%-51.9%
ROCEReturn on capital employed-37.3%-1.0%+29.5%-55.9%
Piotroski ScoreFundamental quality 0–94472
Debt / EquityFinancial leverage0.01x2.61x0.02x0.18x
Net DebtTotal debt minus cash-$17M$27M-$103M-$35M
Cash & Equiv.Liquid assets$18M$9M$108M$111M
Total DebtShort + long-term debt$746,000$36M$5M$76M
Interest CoverageEBIT ÷ Interest expense-129.55x-0.13x32.28x-48.62x
ITRN leads this category, winning 7 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ITRN leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in ITRN five years ago would be worth $28,016 today (with dividends reinvested), compared to $925 for HBIO. Over the past 12 months, HBIO leads with a +126.3% total return vs REPL's -53.4%. The 3-year compound annual growth rate (CAGR) favors ITRN at 45.2% vs HBIO's -51.4% — a key indicator of consistent wealth creation.

MetricABUS logoABUSArbutus Biopharma…HBIO logoHBIOHarvard Bioscienc…ITRN logoITRNIturan Location a…REPL logoREPLReplimune Group, …
YTD ReturnYear-to-date-8.8%+4.1%+42.2%-62.5%
1-Year ReturnPast 12 months+32.2%+126.3%+76.7%-53.4%
3-Year ReturnCumulative with dividends+66.7%-88.5%+206.4%-81.5%
5-Year ReturnCumulative with dividends+54.8%-90.7%+180.2%-90.7%
10-Year ReturnCumulative with dividends+1.4%-76.2%+233.6%-78.0%
CAGR (3Y)Annualised 3-year return+18.6%-51.4%+45.2%-43.0%
ITRN leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ITRN and REPL each lead in 1 of 2 comparable metrics.

REPL is the less volatile stock with a 0.83 beta — it tends to amplify market swings less than HBIO's 2.03 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ITRN currently trades 98.5% from its 52-week high vs REPL's 25.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricABUS logoABUSArbutus Biopharma…HBIO logoHBIOHarvard Bioscienc…ITRN logoITRNIturan Location a…REPL logoREPLReplimune Group, …
Beta (5Y)Sensitivity to S&P 5001.39x2.03x1.18x0.83x
52-Week HighHighest price in past year$5.10$9.46$59.84$13.24
52-Week LowLowest price in past year$2.94$0.59$32.71$1.50
% of 52W HighCurrent price vs 52-week peak+85.3%+71.8%+98.5%+25.2%
RSI (14)Momentum oscillator 0–10052.665.868.346.3
Avg Volume (50D)Average daily shares traded2.3M59K118K5.6M
Evenly matched — ITRN and REPL each lead in 1 of 2 comparable metrics.

Analyst Outlook

ITRN leads this category, winning 1 of 1 comparable metric.

Analyst consensus: ABUS as "Buy", HBIO as "Buy", ITRN as "Hold", REPL as "Buy". Consensus price targets imply 274.3% upside for REPL (target: $13) vs -11.6% for HBIO (target: $6). ITRN is the only dividend payer here at 3.21% yield — a key consideration for income-focused portfolios.

MetricABUS logoABUSArbutus Biopharma…HBIO logoHBIOHarvard Bioscienc…ITRN logoITRNIturan Location a…REPL logoREPLReplimune Group, …
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuy
Price TargetConsensus 12-month target$8.50$6.00$56.00$12.50
# AnalystsCovering analysts105515
Dividend YieldAnnual dividend ÷ price+3.2%
Dividend StreakConsecutive years of raises003
Dividend / ShareAnnual DPS$1.89
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+0.2%0.0%
ITRN leads this category, winning 1 of 1 comparable metric.
Key Takeaway

ITRN leads in 5 of 6 categories — strongest in Income & Cash Flow and Valuation Metrics. 1 category is tied.

Best OverallIturan Location and Control… (ITRN)Leads 5 of 6 categories
Loading custom metrics...

ABUS vs HBIO vs ITRN vs REPL: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is ABUS or HBIO or ITRN or REPL a better buy right now?

For growth investors, Arbutus Biopharma Corporation (ABUS) is the stronger pick with 128.

2% revenue growth year-over-year, versus -8. 1% for Harvard Bioscience, Inc. (HBIO). Ituran Location and Control Ltd. (ITRN) offers the better valuation at 20. 2x trailing P/E (17. 8x forward), making it the more compelling value choice. Analysts rate Arbutus Biopharma Corporation (ABUS) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — ABUS or HBIO or ITRN or REPL?

Over the past 5 years, Ituran Location and Control Ltd.

(ITRN) delivered a total return of +180. 2%, compared to -90. 7% for Harvard Bioscience, Inc. (HBIO). Over 10 years, the gap is even starker: ITRN returned +233. 6% versus REPL's -78. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — ABUS or HBIO or ITRN or REPL?

By beta (market sensitivity over 5 years), Replimune Group, Inc.

(REPL) is the lower-risk stock at 0. 83β versus Harvard Bioscience, Inc. 's 2. 03β — meaning HBIO is approximately 144% more volatile than REPL relative to the S&P 500. On balance sheet safety, Arbutus Biopharma Corporation (ABUS) carries a lower debt/equity ratio of 1% versus 3% for Harvard Bioscience, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — ABUS or HBIO or ITRN or REPL?

By revenue growth (latest reported year), Arbutus Biopharma Corporation (ABUS) is pulling ahead at 128.

2% versus -8. 1% for Harvard Bioscience, Inc. (HBIO). On earnings-per-share growth, the picture is similar: Arbutus Biopharma Corporation grew EPS 55. 3% year-over-year, compared to -357. 1% for Harvard Bioscience, Inc.. Over a 3-year CAGR, ITRN leads at 7. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — ABUS or HBIO or ITRN or REPL?

Ituran Location and Control Ltd.

(ITRN) is the more profitable company, earning 16. 1% net margin versus -237. 9% for Arbutus Biopharma Corporation — meaning it keeps 16. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ITRN leads at 21. 4% versus -271. 0% for ABUS. At the gross margin level — before operating expenses — HBIO leads at 53. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is ABUS or HBIO or ITRN or REPL more undervalued right now?

Analyst consensus price targets imply the most upside for REPL: 274.

3% to $12. 50.

07

Which pays a better dividend — ABUS or HBIO or ITRN or REPL?

In this comparison, ITRN (3.

2% yield) pays a dividend. ABUS, HBIO, REPL do not pay a meaningful dividend and should not be held primarily for income.

08

Is ABUS or HBIO or ITRN or REPL better for a retirement portfolio?

For long-horizon retirement investors, Ituran Location and Control Ltd.

(ITRN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 18), 3. 2% yield, +233. 6% 10Y return). Harvard Bioscience, Inc. (HBIO) carries a higher beta of 2. 03 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ITRN: +233. 6%, HBIO: -76. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between ABUS and HBIO and ITRN and REPL?

These companies operate in different sectors (ABUS (Healthcare) and HBIO (Healthcare) and ITRN (Technology) and REPL (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: ABUS is a small-cap high-growth stock; HBIO is a small-cap quality compounder stock; ITRN is a small-cap income-oriented stock; REPL is a small-cap quality compounder stock. ITRN pays a dividend while ABUS, HBIO, REPL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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