Biotechnology
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ACLX vs DBVT vs SANA vs IMVT vs FATE
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
ACLX vs DBVT vs SANA vs IMVT vs FATE — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $6.73B | $1712.35T | $918M | $5.53B | $280M |
| Revenue (TTM) | $22M | $0.00 | $0.00 | $0.00 | $7M |
| Net Income (TTM) | $-229M | $-168M | $-234M | $-464M | $-136M |
| Gross Margin | -64.8% | — | — | — | — |
| Operating Margin | -11.4% | — | — | — | -22.2% |
| Total Debt | $96M | $22M | $94M | $98K | $78M |
| Cash & Equiv. | $80M | $194M | $128M | $714M | $47M |
ACLX vs DBVT vs SANA vs IMVT vs FATE — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 22 | Apr 26 | Return |
|---|---|---|---|
| Arcellx, Inc. (ACLX) | 100 | 601.2 | +501.2% |
| DBV Technologies S.… (DBVT) | 100 | 155.9 | +55.9% |
| Sana Biotechnology,… (SANA) | 100 | 44.6 | -55.4% |
| Immunovant, Inc. (IMVT) | 100 | 445.2 | +345.2% |
| Fate Therapeutics, … (FATE) | 100 | 3.5 | -96.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ACLX vs DBVT vs SANA vs IMVT vs FATE
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ACLX has the current edge in this matchup, primarily because of its strength in long-term compounding.
- 5.8% 10Y total return vs IMVT's 173.6%
- -36.2% ROA vs DBVT's -89.0%
DBVT is the #2 pick in this set and the best alternative if income & stability is your priority.
- Dividend streak 0 yrs, beta 1.26
- Beta 1.26 vs SANA's 2.69, lower leverage
SANA ranks third and is worth considering specifically for growth.
- 22.6% revenue growth vs DBVT's -100.0%
IMVT is the clearest fit if your priority is sleep-well-at-night and defensive.
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- Beta 1.37, current ratio 11.16x
- 3.2% margin vs FATE's -20.5%
FATE is the clearest fit if your priority is growth exposure.
- Rev growth -51.2%, EPS growth 29.9%, 3Y rev CAGR -59.0%
- +143.0% vs IMVT's +96.1%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 22.6% revenue growth vs DBVT's -100.0% | |
| Quality / Margins | 3.2% margin vs FATE's -20.5% | |
| Stability / Safety | Beta 1.26 vs SANA's 2.69, lower leverage | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +143.0% vs IMVT's +96.1% | |
| Efficiency (ROA) | -36.2% ROA vs DBVT's -89.0% |
ACLX vs DBVT vs SANA vs IMVT vs FATE — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
ACLX vs DBVT vs SANA vs IMVT vs FATE — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ACLX leads in 3 of 6 categories
IMVT leads 1 • DBVT leads 0 • SANA leads 0 • FATE leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ACLX leads this category, winning 3 of 5 comparable metrics.
Income & Cash Flow (Last 12 Months)
ACLX and IMVT operate at a comparable scale, with $22M and $0 in trailing revenue. ACLX is the more profitable business, keeping -10.3% of every revenue dollar as net income compared to FATE's -20.5%. On growth, FATE holds the edge at -26.4% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $22M | $0 | $0 | $0 | $7M |
| EBITDAEarnings before interest/tax | -$246M | -$112M | -$225M | -$487M | -$148M |
| Net IncomeAfter-tax profit | -$229M | -$168M | -$234M | -$464M | -$136M |
| Free Cash FlowCash after capex | -$213M | -$151M | -$159M | -$423M | -$88M |
| Gross MarginGross profit ÷ Revenue | -64.8% | — | — | — | — |
| Operating MarginEBIT ÷ Revenue | -11.4% | — | — | — | -22.2% |
| Net MarginNet income ÷ Revenue | -10.3% | — | — | — | -20.5% |
| FCF MarginFCF ÷ Revenue | -9.5% | — | — | — | -13.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | -89.2% | — | — | — | -26.4% |
| EPS Growth (YoY)Latest quarter vs prior year | -13.6% | +91.5% | +36.0% | +19.7% | +38.6% |
Valuation Metrics
Evenly matched — ACLX and DBVT and FATE each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $6.7B | $1712.35T | $918M | $5.5B | $280M |
| Enterprise ValueMkt cap + debt − cash | $6.7B | $1712.35T | $885M | $4.8B | $312M |
| Trailing P/EPrice ÷ TTM EPS | -28.27x | -0.76x | -3.02x | -9.97x | -2.11x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 302.09x | — | — | — | 42.18x |
| Price / BookPrice ÷ Book value/share | 16.10x | 0.66x | 3.23x | 5.83x | 1.39x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | — |
Profitability & Efficiency
IMVT leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
IMVT delivers a -47.1% return on equity — every $100 of shareholder capital generates $-47 in annual profit, vs $-130 for DBVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to SANA's 0.38x. On the Piotroski fundamental quality scale (0–9), DBVT scores 4/9 vs ACLX's 1/9, reflecting mixed financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -55.4% | -130.2% | -120.0% | -47.1% | -65.8% |
| ROA (TTM)Return on assets | -36.2% | -89.0% | -53.8% | -44.1% | -42.7% |
| ROICReturn on invested capital | -46.2% | — | -86.1% | — | -36.5% |
| ROCEReturn on capital employed | -46.6% | -145.7% | -57.0% | -66.1% | -43.1% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 4 | 2 | 2 | 2 |
| Debt / EquityFinancial leverage | 0.24x | 0.13x | 0.38x | 0.00x | 0.38x |
| Net DebtTotal debt minus cash | $16M | -$172M | -$33M | -$714M | $31M |
| Cash & Equiv.Liquid assets | $80M | $194M | $128M | $714M | $47M |
| Total DebtShort + long-term debt | $96M | $22M | $94M | $98,000 | $78M |
| Interest CoverageEBIT ÷ Interest expense | -8.45x | -189.82x | — | — | — |
Total Returns (Dividends Reinvested)
ACLX leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ACLX five years ago would be worth $68,494 today (with dividends reinvested), compared to $318 for FATE. Over the past 12 months, FATE leads with a +143.0% total return vs IMVT's +96.1%. The 3-year compound annual growth rate (CAGR) favors ACLX at 38.6% vs FATE's -23.6% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +81.7% | +4.9% | -16.5% | +5.1% | +145.5% |
| 1-Year ReturnPast 12 months | +117.4% | +110.4% | +105.9% | +96.1% | +143.0% |
| 3-Year ReturnCumulative with dividends | +166.2% | +19.7% | -36.8% | +40.9% | -55.4% |
| 5-Year ReturnCumulative with dividends | +584.9% | -69.1% | -80.7% | +62.4% | -96.8% |
| 10-Year ReturnCumulative with dividends | +584.9% | -87.0% | -90.0% | +173.6% | +40.5% |
| CAGR (3Y)Annualised 3-year return | +38.6% | +6.2% | -14.2% | +12.1% | -23.6% |
Risk & Volatility
ACLX leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
ACLX is the less volatile stock with a -0.34 beta — it tends to amplify market swings less than SANA's 2.69 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ACLX currently trades 99.9% from its 52-week high vs SANA's 53.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | -0.34x | 1.26x | 2.69x | 1.37x | 2.17x |
| 52-Week HighHighest price in past year | $115.13 | $26.18 | $6.55 | $30.09 | $2.46 |
| 52-Week LowLowest price in past year | $47.86 | $7.53 | $1.60 | $13.36 | $0.91 |
| % of 52W HighCurrent price vs 52-week peak | +99.9% | +76.3% | +53.4% | +90.5% | +98.6% |
| RSI (14)Momentum oscillator 0–100 | 79.9 | 48.1 | 59.0 | 60.2 | 81.0 |
| Avg Volume (50D)Average daily shares traded | 1.6M | 252K | 3.1M | 1.4M | 1.9M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: ACLX as "Hold", DBVT as "Buy", SANA as "Buy", IMVT as "Buy", FATE as "Buy". Consensus price targets imply 1525.5% upside for FATE (target: $40) vs -2.3% for ACLX (target: $112).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $112.45 | $46.33 | $8.67 | $45.50 | $39.50 |
| # AnalystsCovering analysts | 18 | 15 | 11 | 23 | 31 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | 0 | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
ACLX leads in 3 of 6 categories (Income & Cash Flow, Total Returns). IMVT leads in 1 (Profitability & Efficiency). 1 tied.
ACLX vs DBVT vs SANA vs IMVT vs FATE: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is ACLX or DBVT or SANA or IMVT or FATE a better buy right now?
For growth investors, Fate Therapeutics, Inc.
(FATE) is the stronger pick with -51. 2% revenue growth year-over-year, versus -79. 4% for Arcellx, Inc. (ACLX). Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ACLX or DBVT or SANA or IMVT or FATE?
Over the past 5 years, Arcellx, Inc.
(ACLX) delivered a total return of +584. 9%, compared to -96. 8% for Fate Therapeutics, Inc. (FATE). Over 10 years, the gap is even starker: ACLX returned +584. 9% versus SANA's -90. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ACLX or DBVT or SANA or IMVT or FATE?
By beta (market sensitivity over 5 years), Arcellx, Inc.
(ACLX) is the lower-risk stock at -0. 34β versus Sana Biotechnology, Inc. 's 2. 69β — meaning SANA is approximately -894% more volatile than ACLX relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 38% for Sana Biotechnology, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — ACLX or DBVT or SANA or IMVT or FATE?
By revenue growth (latest reported year), Fate Therapeutics, Inc.
(FATE) is pulling ahead at -51. 2% versus -79. 4% for Arcellx, Inc. (ACLX). On earnings-per-share growth, the picture is similar: Fate Therapeutics, Inc. grew EPS 29. 9% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ACLX or DBVT or SANA or IMVT or FATE?
DBV Technologies S.
A. (DBVT) is the more profitable company, earning 0. 0% net margin versus -20. 5% for Fate Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DBVT leads at 0. 0% versus -22. 2% for FATE. At the gross margin level — before operating expenses — ACLX leads at 70. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — ACLX or DBVT or SANA or IMVT or FATE?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is ACLX or DBVT or SANA or IMVT or FATE better for a retirement portfolio?
For long-horizon retirement investors, Arcellx, Inc.
(ACLX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0. 34), +584. 9% 10Y return). Sana Biotechnology, Inc. (SANA) carries a higher beta of 2. 69 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ACLX: +584. 9%, SANA: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between ACLX and DBVT and SANA and IMVT and FATE?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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