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ACLX vs KYMR vs BEAM vs IMVT
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
ACLX vs KYMR vs BEAM vs IMVT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $6.73B | $6.91B | $3.23B | $5.53B |
| Revenue (TTM) | $22M | $51M | $132M | $0.00 |
| Net Income (TTM) | $-229M | $-315M | $-65M | $-464M |
| Gross Margin | -64.8% | 33.2% | -64.2% | — |
| Operating Margin | -11.4% | -7.0% | -281.0% | — |
| Total Debt | $96M | $82M | $294M | $98K |
| Cash & Equiv. | $80M | $357M | $295M | $714M |
ACLX vs KYMR vs BEAM vs IMVT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 22 | Apr 26 | Return |
|---|---|---|---|
| Arcellx, Inc. (ACLX) | 100 | 601.2 | +501.2% |
| Kymera Therapeutics… (KYMR) | 100 | 209.5 | +109.5% |
| Beam Therapeutics I… (BEAM) | 100 | 30.4 | -69.6% |
| Immunovant, Inc. (IMVT) | 100 | 445.2 | +345.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ACLX vs KYMR vs BEAM vs IMVT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ACLX is the clearest fit if your priority is long-term compounding.
- 5.8% 10Y total return vs IMVT's 173.6%
KYMR carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- beta 1.15
- Lower volatility, beta 1.15, Low D/E 5.2%, current ratio 10.47x
- Beta 1.15, current ratio 10.47x
- Beta 1.15 vs BEAM's 2.14, lower leverage
BEAM is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 120.0%, EPS growth 82.3%, 3Y rev CAGR 31.9%
- 120.0% revenue growth vs ACLX's -79.4%
- -4.6% ROA vs IMVT's -44.1%
IMVT is the clearest fit if your priority is quality.
- 3.2% margin vs ACLX's -10.3%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 120.0% revenue growth vs ACLX's -79.4% | |
| Quality / Margins | 3.2% margin vs ACLX's -10.3% | |
| Stability / Safety | Beta 1.15 vs BEAM's 2.14, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +190.7% vs BEAM's +93.9% | |
| Efficiency (ROA) | -4.6% ROA vs IMVT's -44.1% |
ACLX vs KYMR vs BEAM vs IMVT — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
BEAM leads in 3 of 6 categories
ACLX leads 1 • KYMR leads 0 • IMVT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
BEAM leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
BEAM and IMVT operate at a comparable scale, with $132M and $0 in trailing revenue. Profitability is closely matched — net margins range from -49.2% (BEAM) to -10.3% (ACLX). On growth, KYMR holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $22M | $51M | $132M | $0 |
| EBITDAEarnings before interest/tax | -$246M | -$352M | -$355M | -$487M |
| Net IncomeAfter-tax profit | -$229M | -$315M | -$65M | -$464M |
| Free Cash FlowCash after capex | -$213M | -$244M | -$384M | -$423M |
| Gross MarginGross profit ÷ Revenue | -64.8% | +33.2% | -64.2% | — |
| Operating MarginEBIT ÷ Revenue | -11.4% | -7.0% | -2.8% | — |
| Net MarginNet income ÷ Revenue | -10.3% | -6.1% | -49.2% | — |
| FCF MarginFCF ÷ Revenue | -9.5% | -4.7% | -2.9% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | -89.2% | +55.5% | -100.0% | — |
| EPS Growth (YoY)Latest quarter vs prior year | -13.6% | +13.4% | +26.6% | +19.7% |
Valuation Metrics
BEAM leads this category, winning 3 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $6.7B | $6.9B | $3.2B | $5.5B |
| Enterprise ValueMkt cap + debt − cash | $6.7B | $6.6B | $3.2B | $4.8B |
| Trailing P/EPrice ÷ TTM EPS | -28.27x | -22.93x | -38.85x | -9.97x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 302.09x | 176.26x | 23.14x | — |
| Price / BookPrice ÷ Book value/share | 16.10x | 4.52x | 2.51x | 5.83x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
BEAM leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
BEAM delivers a -5.9% return on equity — every $100 of shareholder capital generates $-6 in annual profit, vs $-55 for ACLX. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ACLX's 0.24x. On the Piotroski fundamental quality scale (0–9), KYMR scores 4/9 vs ACLX's 1/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -55.4% | -25.0% | -5.9% | -47.1% |
| ROA (TTM)Return on assets | -36.2% | -22.3% | -4.6% | -44.1% |
| ROICReturn on invested capital | -46.2% | -24.9% | -31.1% | — |
| ROCEReturn on capital employed | -46.6% | -27.2% | -33.3% | -66.1% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 4 | 4 | 2 |
| Debt / EquityFinancial leverage | 0.24x | 0.05x | 0.24x | 0.00x |
| Net DebtTotal debt minus cash | $16M | -$275M | -$1M | -$714M |
| Cash & Equiv.Liquid assets | $80M | $357M | $295M | $714M |
| Total DebtShort + long-term debt | $96M | $82M | $294M | $98,000 |
| Interest CoverageEBIT ÷ Interest expense | -8.45x | -2119.53x | 1.08x | — |
Total Returns (Dividends Reinvested)
Evenly matched — ACLX and KYMR each lead in 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ACLX five years ago would be worth $68,494 today (with dividends reinvested), compared to $4,444 for BEAM. Over the past 12 months, KYMR leads with a +190.7% total return vs BEAM's +93.9%. The 3-year compound annual growth rate (CAGR) favors KYMR at 45.0% vs BEAM's -1.9% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +81.7% | +16.3% | +16.0% | +5.1% |
| 1-Year ReturnPast 12 months | +117.4% | +190.7% | +93.9% | +96.1% |
| 3-Year ReturnCumulative with dividends | +166.2% | +205.1% | -5.6% | +40.9% |
| 5-Year ReturnCumulative with dividends | +584.9% | +92.1% | -55.6% | +62.4% |
| 10-Year ReturnCumulative with dividends | +584.9% | +154.4% | +67.8% | +173.6% |
| CAGR (3Y)Annualised 3-year return | +38.6% | +45.0% | -1.9% | +12.1% |
Risk & Volatility
ACLX leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
ACLX is the less volatile stock with a -0.34 beta — it tends to amplify market swings less than BEAM's 2.14 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ACLX currently trades 99.9% from its 52-week high vs KYMR's 82.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | -0.34x | 1.15x | 2.14x | 1.37x |
| 52-Week HighHighest price in past year | $115.13 | $103.00 | $36.44 | $30.09 |
| 52-Week LowLowest price in past year | $47.86 | $28.06 | $15.35 | $13.36 |
| % of 52W HighCurrent price vs 52-week peak | +99.9% | +82.2% | +86.4% | +90.5% |
| RSI (14)Momentum oscillator 0–100 | 79.9 | 54.1 | 60.9 | 60.2 |
| Avg Volume (50D)Average daily shares traded | 1.6M | 602K | 2.0M | 1.4M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: ACLX as "Hold", KYMR as "Buy", BEAM as "Buy", IMVT as "Buy". Consensus price targets imply 67.2% upside for IMVT (target: $46) vs -2.3% for ACLX (target: $112).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $112.45 | $117.06 | $40.83 | $45.50 |
| # AnalystsCovering analysts | 18 | 26 | 27 | 23 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
BEAM leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). ACLX leads in 1 (Risk & Volatility). 1 tied.
ACLX vs KYMR vs BEAM vs IMVT: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is ACLX or KYMR or BEAM or IMVT a better buy right now?
For growth investors, Beam Therapeutics Inc.
(BEAM) is the stronger pick with 120. 0% revenue growth year-over-year, versus -79. 4% for Arcellx, Inc. (ACLX). Analysts rate Kymera Therapeutics, Inc. (KYMR) a "Buy" — based on 26 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ACLX or KYMR or BEAM or IMVT?
Over the past 5 years, Arcellx, Inc.
(ACLX) delivered a total return of +584. 9%, compared to -55. 6% for Beam Therapeutics Inc. (BEAM). Over 10 years, the gap is even starker: ACLX returned +584. 9% versus BEAM's +67. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ACLX or KYMR or BEAM or IMVT?
By beta (market sensitivity over 5 years), Arcellx, Inc.
(ACLX) is the lower-risk stock at -0. 34β versus Beam Therapeutics Inc. 's 2. 14β — meaning BEAM is approximately -733% more volatile than ACLX relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 24% for Arcellx, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — ACLX or KYMR or BEAM or IMVT?
By revenue growth (latest reported year), Beam Therapeutics Inc.
(BEAM) is pulling ahead at 120. 0% versus -79. 4% for Arcellx, Inc. (ACLX). On earnings-per-share growth, the picture is similar: Beam Therapeutics Inc. grew EPS 82. 3% year-over-year, compared to -103. 5% for Arcellx, Inc.. Over a 3-year CAGR, BEAM leads at 31. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ACLX or KYMR or BEAM or IMVT?
Immunovant, Inc.
(IMVT) is the more profitable company, earning 0. 0% net margin versus -1027. 3% for Arcellx, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -1135. 6% for ACLX. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — ACLX or KYMR or BEAM or IMVT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is ACLX or KYMR or BEAM or IMVT better for a retirement portfolio?
For long-horizon retirement investors, Arcellx, Inc.
(ACLX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0. 34), +584. 9% 10Y return). Beam Therapeutics Inc. (BEAM) carries a higher beta of 2. 14 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ACLX: +584. 9%, BEAM: +67. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between ACLX and KYMR and BEAM and IMVT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ACLX is a small-cap quality compounder stock; KYMR is a small-cap quality compounder stock; BEAM is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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