Biotechnology
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5 / 10Stock Comparison
ACLX vs KYMR vs BEAM vs IMVT vs EDIT
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
ACLX vs KYMR vs BEAM vs IMVT vs EDIT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $6.73B | $6.91B | $3.23B | $5.53B | $297M |
| Revenue (TTM) | $22M | $51M | $132M | $0.00 | $0.00 |
| Net Income (TTM) | $-229M | $-315M | $-65M | $-464M | $-160M |
| Gross Margin | -64.8% | 33.2% | -64.2% | — | — |
| Operating Margin | -11.4% | -7.0% | -281.0% | — | — |
| Total Debt | $96M | $82M | $294M | $98K | $18M |
| Cash & Equiv. | $80M | $357M | $295M | $714M | $147M |
ACLX vs KYMR vs BEAM vs IMVT vs EDIT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 22 | Apr 26 | Return |
|---|---|---|---|
| Arcellx, Inc. (ACLX) | 100 | 601.2 | +501.2% |
| Kymera Therapeutics… (KYMR) | 100 | 209.5 | +109.5% |
| Beam Therapeutics I… (BEAM) | 100 | 30.4 | -69.6% |
| Immunovant, Inc. (IMVT) | 100 | 445.2 | +345.2% |
| Editas Medicine, In… (EDIT) | 100 | 14.4 | -85.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ACLX vs KYMR vs BEAM vs IMVT vs EDIT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ACLX is the clearest fit if your priority is long-term compounding.
- 5.8% 10Y total return vs IMVT's 173.6%
KYMR carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- beta 1.15
- Lower volatility, beta 1.15, Low D/E 5.2%, current ratio 10.47x
- Beta 1.15, current ratio 10.47x
- Beta 1.15 vs EDIT's 2.52, lower leverage
BEAM is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 120.0%, EPS growth 82.3%, 3Y rev CAGR 31.9%
- 120.0% revenue growth vs EDIT's -100.0%
- -4.6% ROA vs EDIT's -74.2%
IMVT ranks third and is worth considering specifically for quality.
- 3.2% margin vs ACLX's -10.3%
Among these 5 stocks, EDIT doesn't own a clear edge in any measured category.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 120.0% revenue growth vs EDIT's -100.0% | |
| Quality / Margins | 3.2% margin vs ACLX's -10.3% | |
| Stability / Safety | Beta 1.15 vs EDIT's 2.52, lower leverage | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +190.7% vs BEAM's +93.9% | |
| Efficiency (ROA) | -4.6% ROA vs EDIT's -74.2% |
ACLX vs KYMR vs BEAM vs IMVT vs EDIT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
ACLX vs KYMR vs BEAM vs IMVT vs EDIT — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
BEAM leads in 3 of 6 categories
ACLX leads 1 • KYMR leads 0 • IMVT leads 0 • EDIT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
BEAM leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
BEAM and EDIT operate at a comparable scale, with $132M and $0 in trailing revenue. Profitability is closely matched — net margins range from -49.2% (BEAM) to -10.3% (ACLX). On growth, KYMR holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $22M | $51M | $132M | $0 | $0 |
| EBITDAEarnings before interest/tax | -$246M | -$352M | -$355M | -$487M | $0 |
| Net IncomeAfter-tax profit | -$229M | -$315M | -$65M | -$464M | -$160M |
| Free Cash FlowCash after capex | -$213M | -$244M | -$384M | -$423M | -$166M |
| Gross MarginGross profit ÷ Revenue | -64.8% | +33.2% | -64.2% | — | — |
| Operating MarginEBIT ÷ Revenue | -11.4% | -7.0% | -2.8% | — | — |
| Net MarginNet income ÷ Revenue | -10.3% | -6.1% | -49.2% | — | — |
| FCF MarginFCF ÷ Revenue | -9.5% | -4.7% | -2.9% | — | — |
| Rev. Growth (YoY)Latest quarter vs prior year | -89.2% | +55.5% | -100.0% | — | -151.6% |
| EPS Growth (YoY)Latest quarter vs prior year | -13.6% | +13.4% | +26.6% | +19.7% | +105.5% |
Valuation Metrics
BEAM leads this category, winning 3 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $6.7B | $6.9B | $3.2B | $5.5B | $297M |
| Enterprise ValueMkt cap + debt − cash | $6.7B | $6.6B | $3.2B | $4.8B | $168M |
| Trailing P/EPrice ÷ TTM EPS | -28.27x | -22.93x | -38.85x | -9.97x | -1.68x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 302.09x | 176.26x | 23.14x | — | — |
| Price / BookPrice ÷ Book value/share | 16.10x | 4.52x | 2.51x | 5.83x | 9.85x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | — |
Profitability & Efficiency
BEAM leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
BEAM delivers a -5.9% return on equity — every $100 of shareholder capital generates $-6 in annual profit, vs $-5 for EDIT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to EDIT's 0.66x. On the Piotroski fundamental quality scale (0–9), KYMR scores 4/9 vs EDIT's 1/9, reflecting mixed financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -55.4% | -25.0% | -5.9% | -47.1% | -5.2% |
| ROA (TTM)Return on assets | -36.2% | -22.3% | -4.6% | -44.1% | -74.2% |
| ROICReturn on invested capital | -46.2% | -24.9% | -31.1% | — | — |
| ROCEReturn on capital employed | -46.6% | -27.2% | -33.3% | -66.1% | — |
| Piotroski ScoreFundamental quality 0–9 | 1 | 4 | 4 | 2 | 1 |
| Debt / EquityFinancial leverage | 0.24x | 0.05x | 0.24x | 0.00x | 0.66x |
| Net DebtTotal debt minus cash | $16M | -$275M | -$1M | -$714M | -$129M |
| Cash & Equiv.Liquid assets | $80M | $357M | $295M | $714M | $147M |
| Total DebtShort + long-term debt | $96M | $82M | $294M | $98,000 | $18M |
| Interest CoverageEBIT ÷ Interest expense | -8.45x | -2119.53x | 1.08x | — | — |
Total Returns (Dividends Reinvested)
Evenly matched — ACLX and KYMR each lead in 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ACLX five years ago would be worth $68,494 today (with dividends reinvested), compared to $888 for EDIT. Over the past 12 months, KYMR leads with a +190.7% total return vs BEAM's +93.9%. The 3-year compound annual growth rate (CAGR) favors KYMR at 45.0% vs EDIT's -32.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +81.7% | +16.3% | +16.0% | +5.1% | +47.8% |
| 1-Year ReturnPast 12 months | +117.4% | +190.7% | +93.9% | +96.1% | +127.8% |
| 3-Year ReturnCumulative with dividends | +166.2% | +205.1% | -5.6% | +40.9% | -68.5% |
| 5-Year ReturnCumulative with dividends | +584.9% | +92.1% | -55.6% | +62.4% | -91.1% |
| 10-Year ReturnCumulative with dividends | +584.9% | +154.4% | +67.8% | +173.6% | -90.0% |
| CAGR (3Y)Annualised 3-year return | +38.6% | +45.0% | -1.9% | +12.1% | -32.0% |
Risk & Volatility
ACLX leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
ACLX is the less volatile stock with a -0.34 beta — it tends to amplify market swings less than EDIT's 2.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ACLX currently trades 99.9% from its 52-week high vs EDIT's 66.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | -0.34x | 1.03x | 2.08x | 1.36x | 2.45x |
| 52-Week HighHighest price in past year | $115.13 | $103.00 | $36.44 | $30.09 | $4.54 |
| 52-Week LowLowest price in past year | $47.86 | $28.06 | $15.35 | $13.36 | $1.29 |
| % of 52W HighCurrent price vs 52-week peak | +99.9% | +82.2% | +86.4% | +90.5% | +66.7% |
| RSI (14)Momentum oscillator 0–100 | 79.9 | 54.1 | 60.9 | 60.2 | 57.5 |
| Avg Volume (50D)Average daily shares traded | 1.6M | 602K | 2.0M | 1.4M | 1.6M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: ACLX as "Hold", KYMR as "Buy", BEAM as "Buy", IMVT as "Buy", EDIT as "Buy". Consensus price targets imply 67.2% upside for IMVT (target: $46) vs -2.3% for ACLX (target: $112).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $112.45 | $118.06 | $40.83 | $45.50 | $5.00 |
| # AnalystsCovering analysts | 18 | 26 | 27 | 23 | 25 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
BEAM leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). ACLX leads in 1 (Risk & Volatility). 1 tied.
ACLX vs KYMR vs BEAM vs IMVT vs EDIT: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is ACLX or KYMR or BEAM or IMVT or EDIT a better buy right now?
For growth investors, Beam Therapeutics Inc.
(BEAM) is the stronger pick with 120. 0% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Analysts rate Kymera Therapeutics, Inc. (KYMR) a "Buy" — based on 26 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ACLX or KYMR or BEAM or IMVT or EDIT?
Over the past 5 years, Arcellx, Inc.
(ACLX) delivered a total return of +584. 9%, compared to -91. 1% for Editas Medicine, Inc. (EDIT). Over 10 years, the gap is even starker: ACLX returned +584. 9% versus EDIT's -89. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ACLX or KYMR or BEAM or IMVT or EDIT?
By beta (market sensitivity over 5 years), Arcellx, Inc.
(ACLX) is the lower-risk stock at -0. 34β versus Editas Medicine, Inc. 's 2. 45β — meaning EDIT is approximately -824% more volatile than ACLX relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 66% for Editas Medicine, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — ACLX or KYMR or BEAM or IMVT or EDIT?
By revenue growth (latest reported year), Beam Therapeutics Inc.
(BEAM) is pulling ahead at 120. 0% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Beam Therapeutics Inc. grew EPS 82. 3% year-over-year, compared to -103. 5% for Arcellx, Inc.. Over a 3-year CAGR, BEAM leads at 31. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ACLX or KYMR or BEAM or IMVT or EDIT?
Immunovant, Inc.
(IMVT) is the more profitable company, earning 0. 0% net margin versus -1027. 3% for Arcellx, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -1135. 6% for ACLX. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — ACLX or KYMR or BEAM or IMVT or EDIT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is ACLX or KYMR or BEAM or IMVT or EDIT better for a retirement portfolio?
For long-horizon retirement investors, Arcellx, Inc.
(ACLX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0. 34), +584. 9% 10Y return). Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 45 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ACLX: +584. 9%, EDIT: -89. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between ACLX and KYMR and BEAM and IMVT and EDIT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ACLX is a small-cap quality compounder stock; KYMR is a small-cap quality compounder stock; BEAM is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; EDIT is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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