Biotechnology
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Side-by-side financial analysisStock Comparison
ADAG vs ABBV vs JPM vs MRK vs BMY
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Banks - Diversified
Drug Manufacturers - General
Drug Manufacturers - General
ADAG vs ABBV vs JPM vs MRK vs BMY — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Banks - Diversified | Drug Manufacturers - General | Drug Manufacturers - General |
| Market Cap | $210M | $402.80B | $896.00B | $294.04B | $116.64B |
| Revenue (TTM) | $103K | $61.16B | $280.33B | $64.93B | $48.48B |
| Net Income (TTM) | $-55M | $4.23B | $57.05B | $18.25B | $7.28B |
| Gross Margin | -10.9% | 70.2% | 60.0% | 74.2% | 68.7% |
| Operating Margin | -589.5% | 26.7% | 25.9% | 41.1% | 25.7% |
| Forward P/E | — | 16.0x | 14.4x | 23.2x | 9.0x |
| Total Debt | $18M | $69.07B | $942.38B | $50.53B | $47.14B |
| Cash & Equiv. | $85M | $5.23B | $343.34B | $14.56B | $10.21B |
ADAG vs ABBV vs JPM vs MRK vs BMY — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 21 | Jun 26 | Return |
|---|---|---|---|
| Adagene Inc. (ADAG) | 100 | 14.6 | -85.4% |
| AbbVie Inc. (ABBV) | 100 | 211.4 | +111.4% |
| JPMorgan Chase & Co. (JPM) | 100 | 217.9 | +117.9% |
| Merck & Co., Inc. (MRK) | 100 | 171.9 | +71.9% |
| Bristol-Myers Squib… (BMY) | 100 | 93.2 | -6.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ADAG vs ABBV vs JPM vs MRK vs BMY
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ADAG ranks third and is worth considering specifically for momentum.
- +82.1% vs BMY's +17.6%
ABBV has the current edge in this matchup, primarily because of its strength in income & stability and growth exposure.
- Dividend streak 43 yrs, beta 0.14, yield 2.9%
- Rev growth 8.6%, EPS growth -0.8%, 3Y rev CAGR 1.8%
- Beta 0.14, yield 2.9%, current ratio 0.67x
- 8.6% revenue growth vs ADAG's -99.4%
JPM is the clearest fit if your priority is long-term compounding and valuation efficiency.
- 465.8% 10Y total return vs ABBV's 362.2%
- PEG 0.81 vs MRK's 1.09
- Lower P/E (14.4x vs 23.2x), PEG 0.81 vs 1.09
MRK is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.
- Lower volatility, beta 0.32, Low D/E 96.0%, current ratio 1.54x
- 28.1% margin vs ADAG's -537.2%
- 14.6% ROA vs ADAG's -83.3%
BMY is the clearest fit if your priority is dividends.
- 4.3% yield, 4-year raise streak, vs ABBV's 2.9%, (1 stock pays no dividend)
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.6% revenue growth vs ADAG's -99.4% | |
| Value | Lower P/E (14.4x vs 23.2x), PEG 0.81 vs 1.09 | |
| Quality / Margins | 28.1% margin vs ADAG's -537.2% | |
| Stability / Safety | Beta 0.14 vs JPM's 0.94 | |
| Dividends | 4.3% yield, 4-year raise streak, vs ABBV's 2.9%, (1 stock pays no dividend) | |
| Momentum (1Y) | +82.1% vs BMY's +17.6% | |
| Efficiency (ROA) | 14.6% ROA vs ADAG's -83.3% |
ADAG vs ABBV vs JPM vs MRK vs BMY — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
ADAG vs ABBV vs JPM vs MRK vs BMY — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
MRK leads in 1 of 6 categories
BMY leads 1 • ADAG leads 1 • ABBV leads 0 • JPM leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
MRK leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
JPM is the larger business by revenue, generating $280.3B annually — 2716299.8x ADAG's $103,204. MRK is the more profitable business, keeping 28.1% of every revenue dollar as net income compared to ADAG's -537.2%. On growth, ABBV holds the edge at +10.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $103,204 | $61.2B | $280.3B | $64.9B | $48.5B |
| EBITDAEarnings before interest/tax | -$59M | $24.5B | $81.4B | $32.4B | $15.7B |
| Net IncomeAfter-tax profit | -$55M | $4.2B | $57.0B | $18.3B | $7.3B |
| Free Cash FlowCash after capex | -$48M | $18.7B | $100.9B | $12.4B | $11.9B |
| Gross MarginGross profit ÷ Revenue | -10.9% | +70.2% | +60.0% | +74.2% | +68.7% |
| Operating MarginEBIT ÷ Revenue | -589.5% | +26.7% | +25.9% | +41.1% | +25.7% |
| Net MarginNet income ÷ Revenue | -537.2% | +6.9% | +20.4% | +28.1% | +15.0% |
| FCF MarginFCF ÷ Revenue | -461.1% | +30.6% | +36.0% | +19.0% | +24.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +10.0% | — | +4.5% | +2.6% |
| EPS Growth (YoY)Latest quarter vs prior year | -50.0% | +57.4% | +16.0% | -19.6% | +9.2% |
Valuation Metrics
BMY leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 16.0x trailing earnings, JPM trades at a 83% valuation discount to ABBV's 96.1x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.77x vs JPM's 0.90x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $210M | $402.8B | $896.0B | $294.0B | $116.6B |
| Enterprise ValueMkt cap + debt − cash | $144M | $466.6B | $1.50T | $330.0B | $153.6B |
| Trailing P/EPrice ÷ TTM EPS | -3.76x | 96.09x | 16.00x | 16.35x | 16.56x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 15.96x | 14.40x | 23.17x | 9.04x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 0.90x | 0.77x | — |
| EV / EBITDAEnterprise value multiple | — | 16.53x | 18.36x | 11.25x | 9.28x |
| Price / SalesMarket cap ÷ Revenue | 2037.00x | 6.59x | 3.20x | 4.53x | 2.42x |
| Price / BookPrice ÷ Book value/share | 2.55x | — | 2.47x | 5.67x | 6.30x |
| Price / FCFMarket cap ÷ FCF | — | 22.61x | 8.88x | 23.79x | 9.08x |
Profitability & Efficiency
Evenly matched — ADAG and MRK each lead in 3 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-146 for ADAG. ADAG carries lower financial leverage with a 0.37x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), BMY scores 8/9 vs ADAG's 1/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -146.2% | +62.1% | +15.9% | +36.1% | +39.0% |
| ROA (TTM)Return on assets | -83.3% | +3.1% | +1.3% | +14.6% | +7.9% |
| ROICReturn on invested capital | — | +23.9% | +4.5% | +22.0% | +16.9% |
| ROCEReturn on capital employed | -53.1% | +21.5% | +8.9% | +23.8% | +18.7% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 6 | 5 | 4 | 8 |
| Debt / EquityFinancial leverage | 0.37x | — | 2.60x | 0.96x | 2.55x |
| Net DebtTotal debt minus cash | -$67M | $63.8B | $599.0B | $36.0B | $36.9B |
| Cash & Equiv.Liquid assets | $85M | $5.2B | $343.3B | $14.6B | $10.2B |
| Total DebtShort + long-term debt | $18M | $69.1B | $942.4B | $50.5B | $47.1B |
| Interest CoverageEBIT ÷ Interest expense | -46.92x | 3.28x | 0.74x | 19.68x | 10.33x |
Total Returns (Dividends Reinvested)
ADAG leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $22,367 today (with dividends reinvested), compared to $2,627 for ADAG. Over the past 12 months, ADAG leads with a +82.1% total return vs BMY's +17.6%. The 3-year compound annual growth rate (CAGR) favors ADAG at 42.3% vs BMY's -0.2% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +94.0% | +0.8% | -0.5% | +12.6% | +9.2% |
| 1-Year ReturnPast 12 months | +82.1% | +21.9% | +21.8% | +49.6% | +17.6% |
| 3-Year ReturnCumulative with dividends | +187.9% | +79.3% | +138.2% | +17.0% | -0.5% |
| 5-Year ReturnCumulative with dividends | -73.7% | +123.7% | +118.2% | +77.7% | +2.1% |
| 10-Year ReturnCumulative with dividends | -88.1% | +362.2% | +465.8% | +169.6% | +6.7% |
| CAGR (3Y)Annualised 3-year return | +42.3% | +21.5% | +33.6% | +5.4% | -0.2% |
Risk & Volatility
Evenly matched — ABBV and MRK each lead in 1 of 2 comparable metrics.
Risk & Volatility
ABBV is the less volatile stock with a 0.14 beta — it tends to amplify market swings less than JPM's 0.94 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRK currently trades 95.1% from its 52-week high vs ADAG's 75.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.73x | 0.14x | 0.94x | 0.32x | 0.34x |
| 52-Week HighHighest price in past year | $4.75 | $244.81 | $337.25 | $125.14 | $62.89 |
| 52-Week LowLowest price in past year | $1.30 | $181.73 | $262.71 | $76.66 | $42.52 |
| % of 52W HighCurrent price vs 52-week peak | +75.2% | +93.0% | +95.1% | +95.1% | +90.8% |
| RSI (14)Momentum oscillator 0–100 | 49.9 | 62.8 | 59.1 | 58.9 | 49.9 |
| Avg Volume (50D)Average daily shares traded | 214K | 4.6M | 7.0M | 7.2M | 8.9M |
Analyst Outlook
Evenly matched — ABBV and BMY each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: ADAG as "Buy", ABBV as "Buy", JPM as "Buy", MRK as "Buy", BMY as "Hold". Consensus price targets imply 40.1% upside for ADAG (target: $5) vs 5.9% for JPM (target: $340). For income investors, BMY offers the higher dividend yield at 4.33% vs JPM's 1.86%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Hold |
| Price TargetConsensus 12-month target | $5.00 | $256.92 | $339.75 | $131.58 | $62.60 |
| # AnalystsCovering analysts | 5 | 41 | 61 | 37 | 41 |
| Dividend YieldAnnual dividend ÷ price | — | +2.9% | +1.9% | +2.7% | +4.3% |
| Dividend StreakConsecutive years of raises | — | 43 | 15 | 15 | 4 |
| Dividend / ShareAnnual DPS | — | $6.57 | $5.95 | $3.26 | $2.47 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.2% | +3.9% | +1.7% | 0.0% |
MRK leads in 1 of 6 categories (Income & Cash Flow). BMY leads in 1 (Valuation Metrics). 3 tied.
ADAG vs ABBV vs JPM vs MRK vs BMY: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ADAG or ABBV or JPM or MRK or BMY a better buy right now?
For growth investors, AbbVie Inc.
(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -99. 4% for Adagene Inc. (ADAG). JPMorgan Chase & Co. (JPM) offers the better valuation at 16. 0x trailing P/E (14. 4x forward), making it the more compelling value choice. Analysts rate Adagene Inc. (ADAG) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ADAG or ABBV or JPM or MRK or BMY?
On trailing P/E, JPMorgan Chase & Co.
(JPM) is the cheapest at 16. 0x versus AbbVie Inc. at 96. 1x. On forward P/E, Bristol-Myers Squibb Company is actually cheaper at 9. 0x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: JPMorgan Chase & Co. wins at 0. 81x versus Merck & Co. , Inc. 's 1. 09x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — ADAG or ABBV or JPM or MRK or BMY?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +123. 7%, compared to -73. 7% for Adagene Inc. (ADAG). Over 10 years, the gap is even starker: JPM returned +465. 8% versus ADAG's -88. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ADAG or ABBV or JPM or MRK or BMY?
By beta (market sensitivity over 5 years), AbbVie Inc.
(ABBV) is the lower-risk stock at 0. 14β versus JPMorgan Chase & Co. 's 0. 94β — meaning JPM is approximately 593% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Adagene Inc. (ADAG) carries a lower debt/equity ratio of 37% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.
05Which is growing faster — ADAG or ABBV or JPM or MRK or BMY?
By revenue growth (latest reported year), AbbVie Inc.
(ABBV) is pulling ahead at 8. 6% versus -99. 4% for Adagene Inc. (ADAG). On earnings-per-share growth, the picture is similar: Bristol-Myers Squibb Company grew EPS 178. 2% year-over-year, compared to -75. 9% for Adagene Inc.. Over a 3-year CAGR, MRK leads at 3. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ADAG or ABBV or JPM or MRK or BMY?
Merck & Co.
, Inc. (MRK) is the more profitable company, earning 28. 1% net margin versus -323. 9% for Adagene Inc. — meaning it keeps 28. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 36. 2% versus -348. 4% for ADAG. At the gross margin level — before operating expenses — MRK leads at 72. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ADAG or ABBV or JPM or MRK or BMY more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, JPMorgan Chase & Co. (JPM) is the more undervalued stock at a PEG of 0. 81x versus Merck & Co. , Inc. 's 1. 09x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Bristol-Myers Squibb Company (BMY) trades at 9. 0x forward P/E versus 23. 2x for Merck & Co. , Inc. — 14. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ADAG: 40. 1% to $5. 00.
08Which pays a better dividend — ADAG or ABBV or JPM or MRK or BMY?
In this comparison, BMY (4.
3% yield), ABBV (2. 9% yield), MRK (2. 7% yield), JPM (1. 9% yield) pay a dividend. ADAG does not pay a meaningful dividend and should not be held primarily for income.
09Is ADAG or ABBV or JPM or MRK or BMY better for a retirement portfolio?
For long-horizon retirement investors, AbbVie Inc.
(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 14), 2. 9% yield, +362. 2% 10Y return). Both have compounded well over 10 years (ABBV: +362. 2%, ADAG: -88. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ADAG and ABBV and JPM and MRK and BMY?
These companies operate in different sectors (ADAG (Healthcare) and ABBV (Healthcare) and JPM (Financial Services) and MRK (Healthcare) and BMY (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: ADAG is a small-cap quality compounder stock; ABBV is a large-cap quality compounder stock; JPM is a large-cap deep-value stock; MRK is a large-cap deep-value stock; BMY is a mid-cap deep-value stock. ABBV, JPM, MRK, BMY pay a dividend while ADAG does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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