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Side-by-side financial analysis
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ADAG
ABBV logo
ABBV
MRK logo
MRK
BMY logo
BMY
REGN logo
REGN
KO logo
KO
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Stock Comparison

ADAG vs ABBV vs MRK vs BMY vs REGN vs KO

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ADAG
Adagene Inc.

Biotechnology

HealthcareNASDAQ • CN
Market Cap$210M
5Y Perf.-85.4%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$402.80B
5Y Perf.+111.4%
MRK
Merck & Co., Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$294.04B
5Y Perf.+71.9%
BMY
Bristol-Myers Squibb Company

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$116.64B
5Y Perf.-6.8%
REGN
Regeneron Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$63.60B
5Y Perf.+35.9%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.61B
5Y Perf.+68.6%

ADAG vs ABBV vs MRK vs BMY vs REGN vs KO — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ADAG logoADAG
ABBV logoABBV
MRK logoMRK
BMY logoBMY
REGN logoREGN
KO logoKO
IndustryBiotechnologyDrug Manufacturers - GeneralDrug Manufacturers - GeneralDrug Manufacturers - GeneralBiotechnologyBeverages - Non-Alcoholic
Market Cap$210M$402.80B$294.04B$116.64B$63.60B$355.61B
Revenue (TTM)$103K$61.16B$64.93B$48.48B$14.92B$49.28B
Net Income (TTM)$-55M$4.23B$18.25B$7.28B$4.42B$13.70B
Gross Margin-10.9%70.2%74.2%68.7%84.5%61.7%
Operating Margin-589.5%26.7%41.1%25.7%24.3%29.3%
Forward P/E16.0x23.2x9.0x13.2x25.3x
Total Debt$18M$69.07B$50.53B$47.14B$2.71B$45.49B
Cash & Equiv.$85M$5.23B$14.56B$10.21B$3.12B$10.27B

ADAG vs ABBV vs MRK vs BMY vs REGN vs KOLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ADAG
ABBV
MRK
BMY
REGN
KO
StockFeb 21Jun 26Return
Adagene Inc. (ADAG)10014.6-85.4%
AbbVie Inc. (ABBV)100211.4+111.4%
Merck & Co., Inc. (MRK)100171.9+71.9%
Bristol-Myers Squib… (BMY)10093.2-6.8%
Regeneron Pharmaceu… (REGN)100135.9+35.9%
The Coca-Cola Compa… (KO)100168.6+68.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: ADAG vs ABBV vs MRK vs BMY vs REGN vs KO

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ABBV and BMY are tied at the top with 2 categories each (6-stock set) — the right choice depends on your priorities. Bristol-Myers Squibb Company is the stronger pick specifically for valuation and capital efficiency and dividend income and shareholder returns. ADAG, MRK, and REGN also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
ADAG
Adagene Inc.
The Momentum Pick

ADAG ranks third and is worth considering specifically for momentum.

  • +82.1% vs KO's +17.2%
Best for: momentum
ABBV
AbbVie Inc.
The Income Pick

ABBV has the current edge in this matchup, primarily because of its strength in income & stability and long-term compounding.

  • Dividend streak 43 yrs, beta 0.14, yield 2.9%
  • 362.2% 10Y total return vs MRK's 169.6%
  • 8.6% revenue growth vs ADAG's -99.4%
  • Beta 0.14 vs ADAG's 0.73
Best for: income & stability and long-term compounding
MRK
Merck & Co., Inc.
The Defensive Pick

MRK is the clearest fit if your priority is sleep-well-at-night and valuation efficiency.

  • Lower volatility, beta 0.32, Low D/E 96.0%, current ratio 1.54x
  • PEG 1.09 vs KO's 2.26
  • Beta 0.32, yield 2.7%, current ratio 1.54x
  • 14.6% ROA vs ADAG's -83.3%
Best for: sleep-well-at-night and valuation efficiency
BMY
Bristol-Myers Squibb Company
The Value Play

BMY is the #2 pick in this set and the best alternative if value and dividends is your priority.

  • Lower P/E (9.0x vs 25.3x)
  • 4.3% yield, 4-year raise streak, vs KO's 2.5%, (1 stock pays no dividend)
Best for: value and dividends
REGN
Regeneron Pharmaceuticals, Inc.
The Quality Compounder

REGN is the clearest fit if your priority is quality.

  • 29.6% margin vs ADAG's -537.2%
Best for: quality
KO
The Coca-Cola Company
The Growth Play

KO is the clearest fit if your priority is growth exposure.

  • Rev growth 1.9%, EPS growth 23.6%, 3Y rev CAGR 3.7%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthABBV logoABBV8.6% revenue growth vs ADAG's -99.4%
ValueBMY logoBMYLower P/E (9.0x vs 25.3x)
Quality / MarginsREGN logoREGN29.6% margin vs ADAG's -537.2%
Stability / SafetyABBV logoABBVBeta 0.14 vs ADAG's 0.73
DividendsBMY logoBMY4.3% yield, 4-year raise streak, vs KO's 2.5%, (1 stock pays no dividend)
Momentum (1Y)ADAG logoADAG+82.1% vs KO's +17.2%
Efficiency (ROA)MRK logoMRK14.6% ROA vs ADAG's -83.3%

ADAG vs ABBV vs MRK vs BMY vs REGN vs KO — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

Discover the Biotech & Healthcare Stocks Theme

These companies are key players in the Biotech & Healthcare Stocks ecosystem. See how they stack up against the rest of the sector.

Explore Theme
ADAGAdagene Inc.
FY 2020
Service
63.9%$398,883
License
36.1%$225,000
ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B
MRKMerck & Co., Inc.
FY 2025
Pharmaceutical segment
89.4%$58.1B
Animal Health segment
9.8%$6.4B
Other Segments
0.8%$515M
BMYBristol-Myers Squibb Company
FY 2025
Eliquis
30.0%$14.4B
Opdivo
20.9%$10.0B
Orencia
7.7%$3.7B
Revlimid
6.1%$3.0B
Yervoy
6.0%$2.9B
Pomalyst/Imnovid
5.7%$2.7B
Reblozyl
4.8%$2.3B
Other (13)
18.9%$9.1B
REGNRegeneron Pharmaceuticals, Inc.
FY 2025
Collaboration Revenue
51.1%$7.3B
Product
44.0%$6.3B
Product and Service, Other
4.9%$703M
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B

ADAG vs ABBV vs MRK vs BMY vs REGN vs KO — Financial Metrics

Side-by-side numbers across 6 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLREGNLAGGINGMRK

Income & Cash Flow (Last 12 Months)

REGN leads this category, winning 3 of 6 comparable metrics.

MRK is the larger business by revenue, generating $64.9B annually — 629103.5x ADAG's $103,204. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to ADAG's -537.2%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricADAG logoADAGAdagene Inc.ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.BMY logoBMYBristol-Myers Squ…REGN logoREGNRegeneron Pharmac…KO logoKOThe Coca-Cola Com…
RevenueTrailing 12 months$103,204$61.2B$64.9B$48.5B$14.9B$49.3B
EBITDAEarnings before interest/tax-$59M$24.5B$32.4B$15.7B$4.2B$15.5B
Net IncomeAfter-tax profit-$55M$4.2B$18.3B$7.3B$4.4B$13.7B
Free Cash FlowCash after capex-$48M$18.7B$12.4B$11.9B$4.2B$12.6B
Gross MarginGross profit ÷ Revenue-10.9%+70.2%+74.2%+68.7%+84.5%+61.7%
Operating MarginEBIT ÷ Revenue-589.5%+26.7%+41.1%+25.7%+24.3%+29.3%
Net MarginNet income ÷ Revenue-537.2%+6.9%+28.1%+15.0%+29.6%+27.8%
FCF MarginFCF ÷ Revenue-461.1%+30.6%+19.0%+24.6%+27.9%+25.5%
Rev. Growth (YoY)Latest quarter vs prior year+10.0%+4.5%+2.6%+19.0%+12.1%
EPS Growth (YoY)Latest quarter vs prior year-50.0%+57.4%-19.6%+9.2%-7.2%+18.2%
REGN leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

BMY leads this category, winning 4 of 7 comparable metrics.

At 14.8x trailing earnings, REGN trades at a 85% valuation discount to ABBV's 96.1x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.77x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.

MetricADAG logoADAGAdagene Inc.ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.BMY logoBMYBristol-Myers Squ…REGN logoREGNRegeneron Pharmac…KO logoKOThe Coca-Cola Com…
Market CapShares × price$210M$402.8B$294.0B$116.6B$63.6B$355.6B
Enterprise ValueMkt cap + debt − cash$144M$466.6B$330.0B$153.6B$63.2B$390.8B
Trailing P/EPrice ÷ TTM EPS-3.76x96.09x16.35x16.56x14.76x27.18x
Forward P/EPrice ÷ next-FY EPS est.15.96x23.17x9.04x13.18x25.27x
PEG RatioP/E ÷ EPS growth rate0.77x2.33x2.43x
EV / EBITDAEnterprise value multiple16.53x11.25x9.28x15.33x26.39x
Price / SalesMarket cap ÷ Revenue2037.00x6.59x4.53x2.42x4.43x7.42x
Price / BookPrice ÷ Book value/share2.55x5.67x6.30x2.13x10.40x
Price / FCFMarket cap ÷ FCF22.61x23.79x9.08x15.59x67.15x
BMY leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

REGN leads this category, winning 3 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-146 for ADAG. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to BMY's 2.55x. On the Piotroski fundamental quality scale (0–9), BMY scores 8/9 vs ADAG's 1/9, reflecting strong financial health.

MetricADAG logoADAGAdagene Inc.ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.BMY logoBMYBristol-Myers Squ…REGN logoREGNRegeneron Pharmac…KO logoKOThe Coca-Cola Com…
ROE (TTM)Return on equity-146.2%+62.1%+36.1%+39.0%+14.3%+41.1%
ROA (TTM)Return on assets-83.3%+3.1%+14.6%+7.9%+11.1%+13.1%
ROICReturn on invested capital+23.9%+22.0%+16.9%+8.9%+15.8%
ROCEReturn on capital employed-53.1%+21.5%+23.8%+18.7%+10.2%+17.3%
Piotroski ScoreFundamental quality 0–9164857
Debt / EquityFinancial leverage0.37x0.96x2.55x0.09x1.33x
Net DebtTotal debt minus cash-$67M$63.8B$36.0B$36.9B-$412M$35.2B
Cash & Equiv.Liquid assets$85M$5.2B$14.6B$10.2B$3.1B$10.3B
Total DebtShort + long-term debt$18M$69.1B$50.5B$47.1B$2.7B$45.5B
Interest CoverageEBIT ÷ Interest expense-46.92x3.28x19.68x10.33x108.44x10.70x
REGN leads this category, winning 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ADAG leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in ABBV five years ago would be worth $22,367 today (with dividends reinvested), compared to $2,627 for ADAG. Over the past 12 months, ADAG leads with a +82.1% total return vs KO's +17.2%. The 3-year compound annual growth rate (CAGR) favors ADAG at 42.3% vs REGN's -6.4% — a key indicator of consistent wealth creation.

MetricADAG logoADAGAdagene Inc.ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.BMY logoBMYBristol-Myers Squ…REGN logoREGNRegeneron Pharmac…KO logoKOThe Coca-Cola Com…
YTD ReturnYear-to-date+94.0%+0.8%+12.6%+9.2%-20.9%+20.3%
1-Year ReturnPast 12 months+82.1%+21.9%+49.6%+17.6%+18.0%+17.2%
3-Year ReturnCumulative with dividends+187.9%+79.3%+17.0%-0.5%-18.1%+47.0%
5-Year ReturnCumulative with dividends-73.7%+123.7%+77.7%+2.1%+16.8%+65.6%
10-Year ReturnCumulative with dividends-88.1%+362.2%+169.6%+6.7%+68.2%+121.1%
CAGR (3Y)Annualised 3-year return+42.3%+21.5%+5.4%-0.2%-6.4%+13.7%
ADAG leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

KO leads this category, winning 2 of 2 comparable metrics.

KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than ADAG's 0.73 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs REGN's 74.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricADAG logoADAGAdagene Inc.ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.BMY logoBMYBristol-Myers Squ…REGN logoREGNRegeneron Pharmac…KO logoKOThe Coca-Cola Com…
Beta (5Y)Sensitivity to S&P 5000.73x0.14x0.32x0.34x0.51x-0.20x
52-Week HighHighest price in past year$4.75$244.81$125.14$62.89$821.11$84.04
52-Week LowLowest price in past year$1.30$181.73$76.66$42.52$503.25$65.35
% of 52W HighCurrent price vs 52-week peak+75.2%+93.0%+95.1%+90.8%+74.6%+98.3%
RSI (14)Momentum oscillator 0–10049.962.858.949.937.560.6
Avg Volume (50D)Average daily shares traded214K4.6M7.2M8.9M868K12.7M
KO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — BMY and KO each lead in 1 of 2 comparable metrics.

Analyst consensus: ADAG as "Buy", ABBV as "Buy", MRK as "Buy", BMY as "Hold", REGN as "Buy", KO as "Buy". Consensus price targets imply 40.1% upside for ADAG (target: $5) vs 4.2% for KO (target: $86). For income investors, BMY offers the higher dividend yield at 4.33% vs REGN's 0.56%.

MetricADAG logoADAGAdagene Inc.ABBV logoABBVAbbVie Inc.MRK logoMRKMerck & Co., Inc.BMY logoBMYBristol-Myers Squ…REGN logoREGNRegeneron Pharmac…KO logoKOThe Coca-Cola Com…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyHoldBuyBuy
Price TargetConsensus 12-month target$5.00$256.92$131.58$62.60$836.00$86.13
# AnalystsCovering analysts54137414848
Dividend YieldAnnual dividend ÷ price+2.9%+2.7%+4.3%+0.6%+2.5%
Dividend StreakConsecutive years of raises43154156
Dividend / ShareAnnual DPS$6.57$3.26$2.47$3.41$2.04
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.2%+1.7%0.0%+6.2%+0.2%
Evenly matched — BMY and KO each lead in 1 of 2 comparable metrics.
Key Takeaway

REGN leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BMY leads in 1 (Valuation Metrics). 1 tied.

Best OverallRegeneron Pharmaceuticals, … (REGN)Leads 2 of 6 categories
Loading custom metrics...

ADAG vs ABBV vs MRK vs BMY vs REGN vs KO: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ADAG or ABBV or MRK or BMY or REGN or KO a better buy right now?

For growth investors, AbbVie Inc.

(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -99. 4% for Adagene Inc. (ADAG). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 14. 8x trailing P/E (13. 2x forward), making it the more compelling value choice. Analysts rate Adagene Inc. (ADAG) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ADAG or ABBV or MRK or BMY or REGN or KO?

On trailing P/E, Regeneron Pharmaceuticals, Inc.

(REGN) is the cheapest at 14. 8x versus AbbVie Inc. at 96. 1x. On forward P/E, Bristol-Myers Squibb Company is actually cheaper at 9. 0x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Merck & Co. , Inc. wins at 1. 09x versus The Coca-Cola Company's 2. 26x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — ADAG or ABBV or MRK or BMY or REGN or KO?

Over the past 5 years, AbbVie Inc.

(ABBV) delivered a total return of +123. 7%, compared to -73. 7% for Adagene Inc. (ADAG). Over 10 years, the gap is even starker: ABBV returned +362. 2% versus ADAG's -88. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ADAG or ABBV or MRK or BMY or REGN or KO?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

20β versus Adagene Inc. 's 0. 73β — meaning ADAG is approximately -465% more volatile than KO relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 3% for Bristol-Myers Squibb Company — giving it more financial flexibility in a downturn.

05

Which is growing faster — ADAG or ABBV or MRK or BMY or REGN or KO?

By revenue growth (latest reported year), AbbVie Inc.

(ABBV) is pulling ahead at 8. 6% versus -99. 4% for Adagene Inc. (ADAG). On earnings-per-share growth, the picture is similar: Bristol-Myers Squibb Company grew EPS 178. 2% year-over-year, compared to -75. 9% for Adagene Inc.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ADAG or ABBV or MRK or BMY or REGN or KO?

Regeneron Pharmaceuticals, Inc.

(REGN) is the more profitable company, earning 31. 4% net margin versus -323. 9% for Adagene Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 36. 2% versus -348. 4% for ADAG. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ADAG or ABBV or MRK or BMY or REGN or KO more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Merck & Co. , Inc. (MRK) is the more undervalued stock at a PEG of 1. 09x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Bristol-Myers Squibb Company (BMY) trades at 9. 0x forward P/E versus 25. 3x for The Coca-Cola Company — 16. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ADAG: 40. 1% to $5. 00.

08

Which pays a better dividend — ADAG or ABBV or MRK or BMY or REGN or KO?

In this comparison, BMY (4.

3% yield), ABBV (2. 9% yield), MRK (2. 7% yield), KO (2. 5% yield), REGN (0. 6% yield) pay a dividend. ADAG does not pay a meaningful dividend and should not be held primarily for income.

09

Is ADAG or ABBV or MRK or BMY or REGN or KO better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

20), 2. 5% yield, +121. 1% 10Y return). Both have compounded well over 10 years (KO: +121. 1%, ADAG: -88. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ADAG and ABBV and MRK and BMY and REGN and KO?

These companies operate in different sectors (ADAG (Healthcare) and ABBV (Healthcare) and MRK (Healthcare) and BMY (Healthcare) and REGN (Healthcare) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: ADAG is a small-cap quality compounder stock; ABBV is a large-cap quality compounder stock; MRK is a large-cap deep-value stock; BMY is a mid-cap deep-value stock; REGN is a mid-cap deep-value stock; KO is a large-cap quality compounder stock. ABBV, MRK, BMY, REGN, KO pay a dividend while ADAG does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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