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AEMD vs XTLB vs SIGA vs NRXP vs AEYE

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
AEMD
Aethlon Medical, Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$359K
5Y Perf.-99.8%
XTLB
XTL Biopharmaceuticals Ltd.

Biotechnology

HealthcareNASDAQ • IL
Market Cap$294K
5Y Perf.-50.2%
SIGA
SIGA Technologies, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$339M
5Y Perf.-21.0%
NRXP
NRx Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$85M
5Y Perf.-97.2%
AEYE
AudioEye, Inc.

Software - Application

TechnologyNASDAQ • US
Market Cap$100M
5Y Perf.-4.5%

AEMD vs XTLB vs SIGA vs NRXP vs AEYE — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
AEMD logoAEMD
XTLB logoXTLB
SIGA logoSIGA
NRXP logoNRXP
AEYE logoAEYE
IndustryMedical - DevicesBiotechnologyDrug Manufacturers - Specialty & GenericBiotechnologySoftware - Application
Market Cap$359K$294K$339M$85M$100M
Revenue (TTM)$0.00$451K$94M$242K$40M
Net Income (TTM)$-2.03B$-1M$-4.04T$-38M$-3M
Gross Margin26.4%61.8%59.5%78.3%
Operating Margin-481.6%27.7%-63.0%-7.9%
Forward P/E2.8x
Total Debt$650K$138K$595K$631K$721K
Cash & Equiv.$6M$371K$155M$8M$5M

AEMD vs XTLB vs SIGA vs NRXP vs AEYELong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

AEMD
XTLB
SIGA
NRXP
AEYE
StockMay 20May 26Return
Aethlon Medical, In… (AEMD)1000.2-99.8%
XTL Biopharmaceutic… (XTLB)10049.8-50.2%
SIGA Technologies, … (SIGA)10079.0-21.0%
NRx Pharmaceuticals… (NRXP)1002.8-97.2%
AudioEye, Inc. (AEYE)10095.5-4.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: AEMD vs XTLB vs SIGA vs NRXP vs AEYE

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: SIGA leads in 3 of 6 categories (5-stock set), making it the strongest pick for capital preservation and lower volatility and dividend income and shareholder returns. NRx Pharmaceuticals, Inc. is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. AEMD also leads in specific categories worth noting. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
AEMD
Aethlon Medical, Inc.
The Quality Compounder

AEMD ranks third and is worth considering specifically for quality.

  • 3.9% margin vs SIGA's -43K%
Best for: quality
XTLB
XTL Biopharmaceuticals Ltd.
The Healthcare Pick

XTLB lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
SIGA
SIGA Technologies, Inc.
The Income Pick

SIGA carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • Dividend streak 4 yrs, beta 1.15, yield 12.7%
  • 7.6% 10Y total return vs AEYE's 102.2%
  • Lower volatility, beta 1.15, Low D/E 0.3%, current ratio 11.83x
  • Beta 1.15, yield 12.7%, current ratio 11.83x
Best for: income & stability and long-term compounding
NRXP
NRx Pharmaceuticals, Inc.
The Growth Leader

NRXP is the #2 pick in this set and the best alternative if growth and momentum is your priority.

  • 101.1% revenue growth vs AEMD's -177.7%
  • +55.3% vs AEMD's -92.3%
Best for: growth and momentum
AEYE
AudioEye, Inc.
The Growth Play

AEYE is the clearest fit if your priority is growth exposure.

  • Rev growth 14.5%, EPS growth 30.6%, 3Y rev CAGR 10.5%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthNRXP logoNRXP101.1% revenue growth vs AEMD's -177.7%
Quality / MarginsAEMD logoAEMD3.9% margin vs SIGA's -43K%
Stability / SafetySIGA logoSIGABeta 1.15 vs AEYE's 2.29, lower leverage
DividendsSIGA logoSIGA12.7% yield; 4-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)NRXP logoNRXP+55.3% vs AEMD's -92.3%
Efficiency (ROA)SIGA logoSIGA-7.4% ROA vs NRXP's -489.9%

AEMD vs XTLB vs SIGA vs NRXP vs AEYE — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

AEMDAethlon Medical, Inc.
FY 2022
Govt Contract And Grant Revenue
100.0%$294,165
XTLBXTL Biopharmaceuticals Ltd.

Segment breakdown not available.

SIGASIGA Technologies, Inc.
FY 2025
Product Sales and Supportive Services
93.1%$88M
Research and Development
6.9%$7M
NRXPNRx Pharmaceuticals, Inc.
FY 2025
Therapy
100.0%$854,000
AEYEAudioEye, Inc.
FY 2024
Enterprise
100.0%$15M

AEMD vs XTLB vs SIGA vs NRXP vs AEYE — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLSIGALAGGINGNRXP

Income & Cash Flow (Last 12 Months)

AEYE leads this category, winning 3 of 6 comparable metrics.

SIGA and AEMD operate at a comparable scale, with $94M and $0 in trailing revenue. AEYE is the more profitable business, keeping -7.6% of every revenue dollar as net income compared to SIGA's -43117.4%. On growth, AEYE holds the edge at +7.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricAEMD logoAEMDAethlon Medical, …XTLB logoXTLBXTL Biopharmaceut…SIGA logoSIGASIGA Technologies…NRXP logoNRXPNRx Pharmaceutica…AEYE logoAEYEAudioEye, Inc.
RevenueTrailing 12 months$0$451,000$94M$242,000$40M
EBITDAEarnings before interest/tax-$5M-$1M$26M-$31M-$504,000
Net IncomeAfter-tax profit-$2.0B-$1M-$4.04T-$38M-$3M
Free Cash FlowCash after capex-$5.3B$0$33M-$12M$2M
Gross MarginGross profit ÷ Revenue+26.4%+61.8%+59.5%+78.3%
Operating MarginEBIT ÷ Revenue-4.8%+27.7%-63.0%-7.9%
Net MarginNet income ÷ Revenue-2.3%-43117.4%-157.3%-7.6%
FCF MarginFCF ÷ Revenue-3.7%+35.2%-49.0%+5.5%
Rev. Growth (YoY)Latest quarter vs prior year-11.3%+7.9%
EPS Growth (YoY)Latest quarter vs prior year+71.5%+20.0%-80.0%+29.0%
AEYE leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

XTLB leads this category, winning 2 of 3 comparable metrics.
MetricAEMD logoAEMDAethlon Medical, …XTLB logoXTLBXTL Biopharmaceut…SIGA logoSIGASIGA Technologies…NRXP logoNRXPNRx Pharmaceutica…AEYE logoAEYEAudioEye, Inc.
Market CapShares × price$358,993$293,767$339M$85M$100M
Enterprise ValueMkt cap + debt − cash-$4M$60,767$185M$78M$96M
Trailing P/EPrice ÷ TTM EPS-0.03x-0.28x14.33x-2.28x-32.36x
Forward P/EPrice ÷ next-FY EPS est.2.78x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple7.60x
Price / SalesMarket cap ÷ Revenue0.65x3.58x69.15x2.49x
Price / BookPrice ÷ Book value/share0.07x0.05x1.70x20.91x
Price / FCFMarket cap ÷ FCF6.96x
XTLB leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

SIGA leads this category, winning 7 of 9 comparable metrics.

SIGA delivers a -10.7% return on equity — every $100 of shareholder capital generates $-11 in annual profit, vs $-48 for AEYE. SIGA carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to AEYE's 0.15x. On the Piotroski fundamental quality scale (0–9), SIGA scores 5/9 vs XTLB's 3/9, reflecting solid financial health.

MetricAEMD logoAEMDAethlon Medical, …XTLB logoXTLBXTL Biopharmaceut…SIGA logoSIGASIGA Technologies…NRXP logoNRXPNRx Pharmaceutica…AEYE logoAEYEAudioEye, Inc.
ROE (TTM)Return on equity-30.2%-25.5%-10.7%-47.8%
ROA (TTM)Return on assets-25.2%-17.7%-7.4%-4.9%-9.5%
ROICReturn on invested capital-9.1%-54.1%+33.7%-42.4%
ROCEReturn on capital employed-157.3%-50.7%+11.3%-17.7%
Piotroski ScoreFundamental quality 0–933554
Debt / EquityFinancial leverage0.13x0.03x0.00x0.15x
Net DebtTotal debt minus cash-$5M-$233,000-$154M-$7M-$5M
Cash & Equiv.Liquid assets$6M$371,000$155M$8M$5M
Total DebtShort + long-term debt$649,751$138,000$595,169$631,000$721,000
Interest CoverageEBIT ÷ Interest expense-939.14x-13.31x-24.18x-2.79x
SIGA leads this category, winning 7 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

SIGA leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in SIGA five years ago would be worth $10,136 today (with dividends reinvested), compared to $17 for AEMD. Over the past 12 months, NRXP leads with a +55.3% total return vs AEMD's -92.3%. The 3-year compound annual growth rate (CAGR) favors SIGA at 6.9% vs AEMD's -79.8% — a key indicator of consistent wealth creation.

MetricAEMD logoAEMDAethlon Medical, …XTLB logoXTLBXTL Biopharmaceut…SIGA logoSIGASIGA Technologies…NRXP logoNRXPNRx Pharmaceutica…AEYE logoAEYEAudioEye, Inc.
YTD ReturnYear-to-date-18.4%+11.3%-15.0%+16.8%-18.7%
1-Year ReturnPast 12 months-92.3%-50.9%+1.5%+55.3%-27.9%
3-Year ReturnCumulative with dividends-99.2%-45.7%+22.2%-50.6%+20.6%
5-Year ReturnCumulative with dividends-99.8%-80.4%+1.4%-99.1%-60.2%
10-Year ReturnCumulative with dividends-100.0%-87.3%+764.0%-96.8%+102.2%
CAGR (3Y)Annualised 3-year return-79.8%-18.4%+6.9%-21.0%+6.4%
SIGA leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — SIGA and NRXP each lead in 1 of 2 comparable metrics.

SIGA is the less volatile stock with a 1.15 beta — it tends to amplify market swings less than AEYE's 2.29 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NRXP currently trades 79.7% from its 52-week high vs AEMD's 6.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricAEMD logoAEMDAethlon Medical, …XTLB logoXTLBXTL Biopharmaceut…SIGA logoSIGASIGA Technologies…NRXP logoNRXPNRx Pharmaceutica…AEYE logoAEYEAudioEye, Inc.
Beta (5Y)Sensitivity to S&P 5001.46x1.71x1.15x1.91x2.29x
52-Week HighHighest price in past year$35.20$10.28$9.62$3.84$16.39
52-Week LowLowest price in past year$1.36$1.05$4.29$1.62$5.31
% of 52W HighCurrent price vs 52-week peak+6.5%+26.0%+49.2%+79.7%+49.4%
RSI (14)Momentum oscillator 0–10061.357.047.064.761.3
Avg Volume (50D)Average daily shares traded42K2.4M688K913K194K
Evenly matched — SIGA and NRXP each lead in 1 of 2 comparable metrics.

Analyst Outlook

SIGA leads this category, winning 1 of 1 comparable metric.

SIGA is the only dividend payer here at 12.73% yield — a key consideration for income-focused portfolios.

MetricAEMD logoAEMDAethlon Medical, …XTLB logoXTLBXTL Biopharmaceut…SIGA logoSIGASIGA Technologies…NRXP logoNRXPNRx Pharmaceutica…AEYE logoAEYEAudioEye, Inc.
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target
# AnalystsCovering analysts1
Dividend YieldAnnual dividend ÷ price+12.7%
Dividend StreakConsecutive years of raises41
Dividend / ShareAnnual DPS$0.60
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%0.0%
SIGA leads this category, winning 1 of 1 comparable metric.
Key Takeaway

SIGA leads in 3 of 6 categories (Profitability & Efficiency, Total Returns). AEYE leads in 1 (Income & Cash Flow). 1 tied.

Best OverallSIGA Technologies, Inc. (SIGA)Leads 3 of 6 categories
Loading custom metrics...

AEMD vs XTLB vs SIGA vs NRXP vs AEYE: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is AEMD or XTLB or SIGA or NRXP or AEYE a better buy right now?

For growth investors, AudioEye, Inc.

(AEYE) is the stronger pick with 14. 5% revenue growth year-over-year, versus -31. 8% for SIGA Technologies, Inc. (SIGA). SIGA Technologies, Inc. (SIGA) offers the better valuation at 14. 3x trailing P/E (2. 8x forward), making it the more compelling value choice. Analysts rate SIGA Technologies, Inc. (SIGA) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — AEMD or XTLB or SIGA or NRXP or AEYE?

Over the past 5 years, SIGA Technologies, Inc.

(SIGA) delivered a total return of +1. 4%, compared to -99. 8% for Aethlon Medical, Inc. (AEMD). Over 10 years, the gap is even starker: SIGA returned +764. 0% versus AEMD's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — AEMD or XTLB or SIGA or NRXP or AEYE?

By beta (market sensitivity over 5 years), SIGA Technologies, Inc.

(SIGA) is the lower-risk stock at 1. 15β versus AudioEye, Inc. 's 2. 29β — meaning AEYE is approximately 99% more volatile than SIGA relative to the S&P 500. On balance sheet safety, SIGA Technologies, Inc. (SIGA) carries a lower debt/equity ratio of 0% versus 15% for AudioEye, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — AEMD or XTLB or SIGA or NRXP or AEYE?

By revenue growth (latest reported year), AudioEye, Inc.

(AEYE) is pulling ahead at 14. 5% versus -31. 8% for SIGA Technologies, Inc. (SIGA). On earnings-per-share growth, the picture is similar: NRx Pharmaceuticals, Inc. grew EPS 43. 9% year-over-year, compared to -76. 5% for Aethlon Medical, Inc.. Over a 3-year CAGR, AEYE leads at 10. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — AEMD or XTLB or SIGA or NRXP or AEYE?

SIGA Technologies, Inc.

(SIGA) is the more profitable company, earning 24. 6% net margin versus -23. 4% for NRx Pharmaceuticals, Inc. — meaning it keeps 24. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: SIGA leads at 25. 1% versus -1324. 4% for NRXP. At the gross margin level — before operating expenses — AEYE leads at 78. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — AEMD or XTLB or SIGA or NRXP or AEYE?

In this comparison, SIGA (12.

7% yield) pays a dividend. AEMD, XTLB, NRXP, AEYE do not pay a meaningful dividend and should not be held primarily for income.

07

Is AEMD or XTLB or SIGA or NRXP or AEYE better for a retirement portfolio?

For long-horizon retirement investors, SIGA Technologies, Inc.

(SIGA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 15), 12. 7% yield, +764. 0% 10Y return). NRx Pharmaceuticals, Inc. (NRXP) carries a higher beta of 1. 91 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SIGA: +764. 0%, NRXP: -96. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between AEMD and XTLB and SIGA and NRXP and AEYE?

These companies operate in different sectors (AEMD (Healthcare) and XTLB (Healthcare) and SIGA (Healthcare) and NRXP (Healthcare) and AEYE (Technology)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: AEMD is a small-cap quality compounder stock; XTLB is a small-cap quality compounder stock; SIGA is a small-cap deep-value stock; NRXP is a small-cap quality compounder stock; AEYE is a small-cap quality compounder stock. SIGA pays a dividend while AEMD, XTLB, NRXP, AEYE do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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