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ALEC vs INMB
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
ALEC vs INMB — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $269M | $38M |
| Revenue (TTM) | $21M | $0.00 |
| Net Income (TTM) | $-143M | $-42M |
| Gross Margin | — | 100.0% |
| Operating Margin | -7.4% | -617.4% |
| Total Debt | $36M | $1M |
| Cash & Equiv. | $66M | $25M |
ALEC vs INMB — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Alector, Inc. (ALEC) | 100 | 7.5 | -92.5% |
| INmune Bio, Inc. (INMB) | 100 | 25.1 | -74.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ALEC vs INMB
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ALEC carries the broadest edge in this set and is the clearest fit for quality and momentum.
- -6.8% margin vs INMB's -918.7%
- +139.2% vs INMB's -80.0%
- -48.7% ROA vs INMB's -128.8%, ROIC -170.3% vs -407.4%
INMB is the clearest fit if your priority is income & stability and growth exposure.
- beta 2.45
- Rev growth 257.1%, EPS growth 11.8%, 3Y rev CAGR -48.9%
- -82.1% 10Y total return vs ALEC's -86.4%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 257.1% revenue growth vs ALEC's -79.1% | |
| Quality / Margins | -6.8% margin vs INMB's -918.7% | |
| Stability / Safety | Beta 2.45 vs ALEC's 2.47, lower leverage | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +139.2% vs INMB's -80.0% | |
| Efficiency (ROA) | -48.7% ROA vs INMB's -128.8%, ROIC -170.3% vs -407.4% |
ALEC vs INMB — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
ALEC vs INMB — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
ALEC leads this category, winning 4 of 5 comparable metrics.
Income & Cash Flow (Last 12 Months)
ALEC and INMB operate at a comparable scale, with $21M and $0 in trailing revenue. ALEC is the more profitable business, keeping -6.8% of every revenue dollar as net income compared to INMB's -918.7%. On growth, ALEC holds the edge at -88.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $21M | $0 |
| EBITDAEarnings before interest/tax | -$156M | -$27M |
| Net IncomeAfter-tax profit | -$143M | -$42M |
| Free Cash FlowCash after capex | -$184M | -$21M |
| Gross MarginGross profit ÷ Revenue | — | +100.0% |
| Operating MarginEBIT ÷ Revenue | -7.4% | -617.4% |
| Net MarginNet income ÷ Revenue | -6.8% | -918.7% |
| FCF MarginFCF ÷ Revenue | -8.7% | -472.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | -88.5% | -100.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -15.1% | +53.5% |
Valuation Metrics
ALEC leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $269M | $38M |
| Enterprise ValueMkt cap + debt − cash | $240M | $14M |
| Trailing P/EPrice ÷ TTM EPS | -1.76x | -0.77x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 12.80x | 760.34x |
| Price / BookPrice ÷ Book value/share | 8.20x | 1.62x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
Evenly matched — ALEC and INMB each lead in 4 of 8 comparable metrics.
Profitability & Efficiency
INMB delivers a -170.9% return on equity — every $100 of shareholder capital generates $-171 in annual profit, vs $-5 for ALEC. INMB carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to ALEC's 1.18x. On the Piotroski fundamental quality scale (0–9), INMB scores 3/9 vs ALEC's 1/9, reflecting mixed financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -4.7% | -170.9% |
| ROA (TTM)Return on assets | -48.7% | -128.8% |
| ROICReturn on invested capital | -170.3% | -4.1% |
| ROCEReturn on capital employed | -55.0% | -109.7% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 3 |
| Debt / EquityFinancial leverage | 1.18x | 0.04x |
| Net DebtTotal debt minus cash | -$30M | -$24M |
| Cash & Equiv.Liquid assets | $66M | $25M |
| Total DebtShort + long-term debt | $36M | $1M |
| Interest CoverageEBIT ÷ Interest expense | — | — |
Total Returns (Dividends Reinvested)
ALEC leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ALEC five years ago would be worth $1,492 today (with dividends reinvested), compared to $1,338 for INMB. Over the past 12 months, ALEC leads with a +139.2% total return vs INMB's -80.0%. The 3-year compound annual growth rate (CAGR) favors ALEC at -32.5% vs INMB's -44.5% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +59.5% | -7.1% |
| 1-Year ReturnPast 12 months | +139.2% | -80.0% |
| 3-Year ReturnCumulative with dividends | -69.2% | -82.9% |
| 5-Year ReturnCumulative with dividends | -85.1% | -86.6% |
| 10-Year ReturnCumulative with dividends | -86.4% | -82.1% |
| CAGR (3Y)Annualised 3-year return | -32.5% | -44.5% |
Risk & Volatility
Evenly matched — ALEC and INMB each lead in 1 of 2 comparable metrics.
Risk & Volatility
INMB is the less volatile stock with a 2.45 beta — it tends to amplify market swings less than ALEC's 2.47 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALEC currently trades 71.8% from its 52-week high vs INMB's 12.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.47x | 2.45x |
| 52-Week HighHighest price in past year | $3.40 | $11.64 |
| 52-Week LowLowest price in past year | $0.97 | $1.09 |
| % of 52W HighCurrent price vs 52-week peak | +71.8% | +12.3% |
| RSI (14)Momentum oscillator 0–100 | 59.1 | 59.2 |
| Avg Volume (50D)Average daily shares traded | 684K | 384K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | — |
| Price TargetConsensus 12-month target | $3.50 | — |
| # AnalystsCovering analysts | 14 | — |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
ALEC leads in 3 of 6 categories — strongest in Income & Cash Flow and Valuation Metrics. 2 categories are tied.
ALEC vs INMB: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is ALEC or INMB a better buy right now?
For growth investors, INmune Bio, Inc.
(INMB) is the stronger pick with 257. 1% revenue growth year-over-year, versus -79. 1% for Alector, Inc. (ALEC). Analysts rate Alector, Inc. (ALEC) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ALEC or INMB?
Over the past 5 years, Alector, Inc.
(ALEC) delivered a total return of -85. 1%, compared to -86. 6% for INmune Bio, Inc. (INMB). Over 10 years, the gap is even starker: INMB returned -82. 1% versus ALEC's -86. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ALEC or INMB?
By beta (market sensitivity over 5 years), INmune Bio, Inc.
(INMB) is the lower-risk stock at 2. 45β versus Alector, Inc. 's 2. 47β — meaning ALEC is approximately 1% more volatile than INMB relative to the S&P 500. On balance sheet safety, INmune Bio, Inc. (INMB) carries a lower debt/equity ratio of 4% versus 118% for Alector, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — ALEC or INMB?
By revenue growth (latest reported year), INmune Bio, Inc.
(INMB) is pulling ahead at 257. 1% versus -79. 1% for Alector, Inc. (ALEC). On earnings-per-share growth, the picture is similar: INmune Bio, Inc. grew EPS 11. 8% year-over-year, compared to -13. 0% for Alector, Inc.. Over a 3-year CAGR, ALEC leads at -46. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ALEC or INMB?
Alector, Inc.
(ALEC) is the more profitable company, earning -679. 2% net margin versus -918. 7% for INmune Bio, Inc. — meaning it keeps -679. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ALEC leads at -741. 3% versus -617. 4% for INMB. At the gross margin level — before operating expenses — INMB leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — ALEC or INMB?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is ALEC or INMB better for a retirement portfolio?
For long-horizon retirement investors, INmune Bio, Inc.
(INMB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Alector, Inc. (ALEC) carries a higher beta of 2. 47 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (INMB: -82. 1%, ALEC: -86. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between ALEC and INMB?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ALEC is a small-cap quality compounder stock; INMB is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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