Biotechnology
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ALKS vs INVA vs PRGO vs TEVA
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - Specialty & Generic
ALKS vs INVA vs PRGO vs TEVA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic |
| Market Cap | $6.12B | $1.69B | $1.60B | $41.76B |
| Revenue (TTM) | $1.48B | $415M | $4.25B | $17.35B |
| Net Income (TTM) | $242M | $271M | $-1.43B | $1.56B |
| Gross Margin | 86.3% | 78.9% | 35.1% | 52.1% |
| Operating Margin | 17.2% | -4.0% | -26.4% | 13.2% |
| Forward P/E | 25.3x | 11.8x | 5.5x | 14.7x |
| Total Debt | $70M | $0.00 | $37M | $17.38B |
| Cash & Equiv. | $1.12B | $551M | $532M | $3.56B |
ALKS vs INVA vs PRGO vs TEVA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Alkermes plc (ALKS) | 100 | 215.9 | +115.9% |
| Innoviva, Inc. (INVA) | 100 | 161.2 | +61.2% |
| Perrigo Company plc (PRGO) | 100 | 22.4 | -77.6% |
| Teva Pharmaceutical… (TEVA) | 100 | 290.0 | +190.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ALKS vs INVA vs PRGO vs TEVA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ALKS is the clearest fit if your priority is income & stability.
- Dividend streak 0 yrs, beta 1.06
INVA carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
- 96.4% 10Y total return vs TEVA's -30.0%
- Lower volatility, beta 0.13, current ratio 14.64x
- Beta 0.13, current ratio 14.64x
PRGO is the #2 pick in this set and the best alternative if value and dividends is your priority.
- Lower P/E (5.5x vs 14.7x)
- 9.9% yield; 10-year raise streak; the other 3 pay no meaningful dividend
TEVA is the clearest fit if your priority is momentum.
- +118.8% vs PRGO's -49.3%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 18.5% revenue growth vs ALKS's -5.2% | |
| Value | Lower P/E (5.5x vs 14.7x) | |
| Quality / Margins | 65.4% margin vs PRGO's -33.5% | |
| Stability / Safety | Beta 0.13 vs PRGO's 1.18 | |
| Dividends | 9.9% yield; 10-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +118.8% vs PRGO's -49.3% | |
| Efficiency (ROA) | 16.6% ROA vs PRGO's -16.7%, ROIC 16.8% vs -17.1% |
ALKS vs INVA vs PRGO vs TEVA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
ALKS vs INVA vs PRGO vs TEVA — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
PRGO leads in 2 of 6 categories
INVA leads 1 • ALKS leads 1 • TEVA leads 1 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
INVA leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
TEVA is the larger business by revenue, generating $17.3B annually — 41.8x INVA's $415M. INVA is the more profitable business, keeping 65.4% of every revenue dollar as net income compared to PRGO's -33.5%. On growth, INVA holds the edge at +28.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $1.5B | $415M | $4.3B | $17.3B |
| EBITDAEarnings before interest/tax | $281M | $13M | -$1.1B | $3.3B |
| Net IncomeAfter-tax profit | $242M | $271M | -$1.4B | $1.6B |
| Free Cash FlowCash after capex | $480M | $195M | $145M | $1.2B |
| Gross MarginGross profit ÷ Revenue | +86.3% | +78.9% | +35.1% | +52.1% |
| Operating MarginEBIT ÷ Revenue | +17.2% | -4.0% | -26.4% | +13.2% |
| Net MarginNet income ÷ Revenue | +16.4% | +65.4% | -33.5% | +9.0% |
| FCF MarginFCF ÷ Revenue | +32.5% | +46.9% | +3.4% | +6.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | -10.6% | +28.6% | -2.5% | +2.3% |
| EPS Growth (YoY)Latest quarter vs prior year | -67.0% | +7.1% | -31.0% | +72.2% |
Valuation Metrics
PRGO leads this category, winning 4 of 6 comparable metrics.
Valuation Metrics
At 6.9x trailing earnings, INVA trades at a 77% valuation discount to TEVA's 29.9x P/E. On an enterprise value basis, INVA's 5.6x EV/EBITDA is more attractive than ALKS's 18.0x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $6.1B | $1.7B | $1.6B | $41.8B |
| Enterprise ValueMkt cap + debt − cash | $5.1B | $1.1B | $1.1B | $55.6B |
| Trailing P/EPrice ÷ TTM EPS | 25.35x | 6.86x | -1.13x | 29.88x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 11.77x | 5.52x | 14.68x |
| PEG RatioP/E ÷ EPS growth rate | — | 0.67x | — | — |
| EV / EBITDAEnterprise value multiple | 18.02x | 5.59x | — | 17.59x |
| Price / SalesMarket cap ÷ Revenue | 4.14x | 3.98x | 0.38x | 2.42x |
| Price / BookPrice ÷ Book value/share | 3.36x | 1.64x | 0.55x | 5.32x |
| Price / FCFMarket cap ÷ FCF | 12.73x | 8.63x | 11.04x | 36.37x |
Profitability & Efficiency
ALKS leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
INVA delivers a 23.1% return on equity — every $100 of shareholder capital generates $23 in annual profit, vs $-49 for PRGO. PRGO carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to TEVA's 2.20x. On the Piotroski fundamental quality scale (0–9), TEVA scores 8/9 vs INVA's 4/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | +14.5% | +23.1% | -48.6% | +20.7% |
| ROA (TTM)Return on assets | +10.5% | +16.6% | -16.7% | +3.9% |
| ROICReturn on invested capital | +18.9% | +16.8% | -17.1% | +7.7% |
| ROCEReturn on capital employed | +14.2% | +12.4% | -13.9% | +8.0% |
| Piotroski ScoreFundamental quality 0–9 | 7 | 4 | 5 | 8 |
| Debt / EquityFinancial leverage | 0.04x | — | 0.01x | 2.20x |
| Net DebtTotal debt minus cash | -$1.0B | -$551M | -$495M | $13.8B |
| Cash & Equiv.Liquid assets | $1.1B | $551M | $532M | $3.6B |
| Total DebtShort + long-term debt | $70M | $0 | $37M | $17.4B |
| Interest CoverageEBIT ÷ Interest expense | 24.74x | 11.03x | -6.91x | 2.51x |
Total Returns (Dividends Reinvested)
TEVA leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in TEVA five years ago would be worth $34,614 today (with dividends reinvested), compared to $4,057 for PRGO. Over the past 12 months, TEVA leads with a +118.8% total return vs PRGO's -49.3%. The 3-year compound annual growth rate (CAGR) favors TEVA at 59.9% vs PRGO's -25.1% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +28.3% | +14.0% | -14.1% | +15.9% |
| 1-Year ReturnPast 12 months | +15.4% | +20.9% | -49.3% | +118.8% |
| 3-Year ReturnCumulative with dividends | +23.1% | +92.8% | -58.0% | +308.9% |
| 5-Year ReturnCumulative with dividends | +64.4% | +96.3% | -59.4% | +246.1% |
| 10-Year ReturnCumulative with dividends | -4.6% | +96.4% | -78.5% | -30.0% |
| CAGR (3Y)Annualised 3-year return | +7.2% | +24.5% | -25.1% | +59.9% |
Risk & Volatility
Evenly matched — ALKS and INVA each lead in 1 of 2 comparable metrics.
Risk & Volatility
INVA is the less volatile stock with a 0.13 beta — it tends to amplify market swings less than PRGO's 1.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALKS currently trades 99.2% from its 52-week high vs PRGO's 40.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.06x | 0.13x | 1.18x | 1.13x |
| 52-Week HighHighest price in past year | $36.55 | $25.15 | $28.44 | $37.35 |
| 52-Week LowLowest price in past year | $25.17 | $16.52 | $9.23 | $14.99 |
| % of 52W HighCurrent price vs 52-week peak | +99.2% | +90.1% | +40.9% | +96.0% |
| RSI (14)Momentum oscillator 0–100 | 57.1 | 45.8 | 50.2 | 70.2 |
| Avg Volume (50D)Average daily shares traded | 2.3M | 620K | 3.3M | 6.4M |
Analyst Outlook
PRGO leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: ALKS as "Buy", INVA as "Buy", PRGO as "Hold", TEVA as "Buy". Consensus price targets imply 71.8% upside for PRGO (target: $20) vs 8.8% for TEVA (target: $39). PRGO is the only dividend payer here at 9.88% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Hold | Buy |
| Price TargetConsensus 12-month target | $44.00 | $37.67 | $20.00 | $39.00 |
| # AnalystsCovering analysts | 28 | 10 | 36 | 46 |
| Dividend YieldAnnual dividend ÷ price | — | — | +9.9% | — |
| Dividend StreakConsecutive years of raises | 0 | 0 | 10 | 1 |
| Dividend / ShareAnnual DPS | — | — | $1.15 | — |
| Buyback YieldShare repurchases ÷ mkt cap | +0.5% | +0.3% | 0.0% | 0.0% |
PRGO leads in 2 of 6 categories (Valuation Metrics, Analyst Outlook). INVA leads in 1 (Income & Cash Flow). 1 tied.
ALKS vs INVA vs PRGO vs TEVA: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ALKS or INVA or PRGO or TEVA a better buy right now?
For growth investors, Innoviva, Inc.
(INVA) is the stronger pick with 18. 5% revenue growth year-over-year, versus -5. 2% for Alkermes plc (ALKS). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (11. 8x forward), making it the more compelling value choice. Analysts rate Alkermes plc (ALKS) a "Buy" — based on 28 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ALKS or INVA or PRGO or TEVA?
On trailing P/E, Innoviva, Inc.
(INVA) is the cheapest at 6. 9x versus Teva Pharmaceutical Industries Limited at 29. 9x. On forward P/E, Perrigo Company plc is actually cheaper at 5. 5x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — ALKS or INVA or PRGO or TEVA?
Over the past 5 years, Teva Pharmaceutical Industries Limited (TEVA) delivered a total return of +246.
1%, compared to -59. 4% for Perrigo Company plc (PRGO). Over 10 years, the gap is even starker: INVA returned +90. 5% versus PRGO's -78. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ALKS or INVA or PRGO or TEVA?
By beta (market sensitivity over 5 years), Innoviva, Inc.
(INVA) is the lower-risk stock at 0. 13β versus Perrigo Company plc's 1. 18β — meaning PRGO is approximately 837% more volatile than INVA relative to the S&P 500. On balance sheet safety, Perrigo Company plc (PRGO) carries a lower debt/equity ratio of 1% versus 2% for Teva Pharmaceutical Industries Limited — giving it more financial flexibility in a downturn.
05Which is growing faster — ALKS or INVA or PRGO or TEVA?
By revenue growth (latest reported year), Innoviva, Inc.
(INVA) is pulling ahead at 18. 5% versus -5. 2% for Alkermes plc (ALKS). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, ALKS leads at 9. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ALKS or INVA or PRGO or TEVA?
Innoviva, Inc.
(INVA) is the more profitable company, earning 63. 8% net margin versus -33. 5% for Perrigo Company plc — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -26. 4% for PRGO. At the gross margin level — before operating expenses — ALKS leads at 86. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ALKS or INVA or PRGO or TEVA more undervalued right now?
On forward earnings alone, Perrigo Company plc (PRGO) trades at 5.
5x forward P/E versus 14. 7x for Teva Pharmaceutical Industries Limited — 9. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PRGO: 71. 8% to $20. 00.
08Which pays a better dividend — ALKS or INVA or PRGO or TEVA?
In this comparison, PRGO (9.
9% yield) pays a dividend. ALKS, INVA, TEVA do not pay a meaningful dividend and should not be held primarily for income.
09Is ALKS or INVA or PRGO or TEVA better for a retirement portfolio?
For long-horizon retirement investors, Innoviva, Inc.
(INVA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 13)). Both have compounded well over 10 years (INVA: +90. 5%, TEVA: -24. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ALKS and INVA and PRGO and TEVA?
Both stocks operate in the null sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ALKS is a small-cap quality compounder stock; INVA is a small-cap high-growth stock; PRGO is a small-cap income-oriented stock; TEVA is a mid-cap quality compounder stock. PRGO pays a dividend while ALKS, INVA, TEVA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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