ALXO
ALX Oncology Holdings Inc.
Biotechnology
Market Cap$112M
5Y Perf.-93.6%
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Stock Comparison
ALXO vs IMVT
Revenue, margins, valuation, and 5-year total return — side by side.
IMVT
Immunovant, Inc.
Biotechnology
Market Cap$5.83B
5Y Perf.+26.8%
ALXO vs IMVT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ALXO | IMVT |
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $112M | $5.83B |
| Revenue (TTM) | $0.00 | $0.00 |
| Net Income (TTM) | $-108M | $-464M |
| Total Debt | $17M | $98K |
| Cash & Equiv. | $18M | $714M |
ALXO vs IMVT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
ALXO
IMVT
| Stock | Jul 20 | May 26 | Return |
|---|---|---|---|
| ALX Oncology Holdin… (ALXO) | 100 | 6.4 | -93.6% |
| Immunovant, Inc. (IMVT) | 100 | 126.8 | +26.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ALXO vs IMVT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Bottom line: ALXO leads in 3 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Immunovant, Inc. is the stronger pick specifically for capital preservation and lower volatility and operational efficiency and capital deployment. As sector peers, any of these can serve as alternatives in the same allocation.
ALXO
ALX Oncology Holdings Inc.
The Growth Play
ALXO carries the broadest edge in this set and is the clearest fit for growth exposure.
- EPS growth 31.0%
- 28.6% revenue growth vs IMVT's -21.3%
- 5.2% margin vs IMVT's 3.2%
Best for: growth exposure
IMVT
Immunovant, Inc.
The Income Pick
IMVT is the clearest fit if your priority is income & stability and long-term compounding.
- beta 1.37
- 188.1% 10Y total return vs ALXO's -93.0%
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
Best for: income & stability and long-term compounding
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | ALXO | 28.6% revenue growth vs IMVT's -21.3% |
| Quality / Margins | ALXO | 5.2% margin vs IMVT's 3.2% |
| Stability / Safety | IMVT | Beta 1.37 vs ALXO's 1.44, lower leverage |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | ALXO | +314.9% vs IMVT's +107.2% |
| Efficiency (ROA) | IMVT | -44.1% ROA vs ALXO's -130.6% |
ALXO vs IMVT — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
BEST OVERALLIMVTLAGGINGALXO
ALXOALX Oncology Holdings…
1leads
IMVTImmunovant, Inc.
3leads
6 Total Categories
CATEGORYLEADERvs ALXOMETRICS WON
Income & Cash FlowRevenue, margins, and cash flow strength
ALXO1/1
Valuation MetricsMultiples, price ratios, and targets
Tied
—
Profitability & EfficiencyROE, ROIC, leverage, and quality scores
IMVT6/6
Total Returns1Y, 3Y, 5Y total returns with dividends
IMVT4/6
Risk & VolatilityBeta, volatility, and downside exposure
IMVT2/2
Analyst OutlookRatings, price targets, and dividends
—
—
Income & Cash Flow (Last 12 Months)
ALXO leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
ALXO and IMVT operate at a comparable scale, with $0 and $0 in trailing revenue.
| Metric | ALXOALX Oncology Hold… | IMVTImmunovant, Inc. |
|---|---|---|
| RevenueTrailing 12 months | $0 | $0 |
| EBITDAEarnings before interest/tax | -$111M | -$487M |
| Net IncomeAfter-tax profit | -$108M | -$464M |
| Free Cash FlowCash after capex | -$97M | -$423M |
| Gross MarginGross profit ÷ Revenue | — | — |
| Operating MarginEBIT ÷ Revenue | — | — |
| Net MarginNet income ÷ Revenue | — | — |
| FCF MarginFCF ÷ Revenue | — | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — |
| EPS Growth (YoY)Latest quarter vs prior year | +29.3% | +19.7% |
ALXO leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
Evenly matched — ALXO and IMVT each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ALXOALX Oncology Hold… | IMVTImmunovant, Inc. |
|---|---|---|
| Market CapShares × price | $112M | $5.8B |
| Enterprise ValueMkt cap + debt − cash | $111M | $5.1B |
| Trailing P/EPrice ÷ TTM EPS | -0.81x | -10.50x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | — | — |
| Price / BookPrice ÷ Book value/share | 0.96x | 6.14x |
| Price / FCFMarket cap ÷ FCF | — | — |
Evenly matched — ALXO and IMVT each lead in 1 of 2 comparable metrics.
Profitability & Efficiency
IMVT leads this category, winning 6 of 6 comparable metrics.
Profitability & Efficiency
IMVT delivers a -47.1% return on equity — every $100 of shareholder capital generates $-47 in annual profit, vs $-2 for ALXO. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ALXO's 0.15x.
| Metric | ALXOALX Oncology Hold… | IMVTImmunovant, Inc. |
|---|---|---|
| ROE (TTM)Return on equity | -2.4% | -47.1% |
| ROA (TTM)Return on assets | -130.6% | -44.1% |
| ROICReturn on invested capital | -71.8% | — |
| ROCEReturn on capital employed | -84.8% | -66.1% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 2 |
| Debt / EquityFinancial leverage | 0.15x | 0.00x |
| Net DebtTotal debt minus cash | -$589,000 | -$714M |
| Cash & Equiv.Liquid assets | $18M | $714M |
| Total DebtShort + long-term debt | $17M | $98,000 |
| Interest CoverageEBIT ÷ Interest expense | -64.62x | — |
IMVT leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
IMVT leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $17,386 today (with dividends reinvested), compared to $333 for ALXO. Over the past 12 months, ALXO leads with a +314.9% total return vs IMVT's +107.2%. The 3-year compound annual growth rate (CAGR) favors IMVT at 14.1% vs ALXO's -30.1% — a key indicator of consistent wealth creation.
| Metric | ALXOALX Oncology Hold… | IMVTImmunovant, Inc. |
|---|---|---|
| YTD ReturnYear-to-date | +81.7% | +10.7% |
| 1-Year ReturnPast 12 months | +314.9% | +107.2% |
| 3-Year ReturnCumulative with dividends | -65.9% | +48.4% |
| 5-Year ReturnCumulative with dividends | -96.7% | +73.9% |
| 10-Year ReturnCumulative with dividends | -93.0% | +188.1% |
| CAGR (3Y)Annualised 3-year return | -30.1% | +14.1% |
IMVT leads this category, winning 4 of 6 comparable metrics.
Risk & Volatility
IMVT leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
IMVT is the less volatile stock with a 1.37 beta — it tends to amplify market swings less than ALXO's 1.44 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 95.3% from its 52-week high vs ALXO's 78.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ALXOALX Oncology Hold… | IMVTImmunovant, Inc. |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.44x | 1.37x |
| 52-Week HighHighest price in past year | $2.66 | $30.09 |
| 52-Week LowLowest price in past year | $0.40 | $13.36 |
| % of 52W HighCurrent price vs 52-week peak | +78.6% | +95.3% |
| RSI (14)Momentum oscillator 0–100 | 57.7 | 55.7 |
| Avg Volume (50D)Average daily shares traded | 930K | 1.4M |
IMVT leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates ALXO as "Buy" and IMVT as "Buy". Consensus price targets imply 91.4% upside for ALXO (target: $4) vs 58.7% for IMVT (target: $46).
| Metric | ALXOALX Oncology Hold… | IMVTImmunovant, Inc. |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $4.00 | $45.50 |
| # AnalystsCovering analysts | 7 | 23 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
Insufficient data to determine a leader in this category.
Key Takeaway
IMVT leads in 3 of 6 categories (Profitability & Efficiency, Total Returns). ALXO leads in 1 (Income & Cash Flow). 1 tied.
Best OverallImmunovant, Inc. (IMVT)Leads 3 of 6 categories
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ALXO vs IMVT: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is ALXO or IMVT a better buy right now?
Analysts rate ALX Oncology Holdings Inc.
(ALXO) a "Buy" — based on 7 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ALXO or IMVT?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +73. 9%, compared to -96. 7% for ALX Oncology Holdings Inc. (ALXO). Over 10 years, the gap is even starker: IMVT returned +188. 1% versus ALXO's -93. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ALXO or IMVT?
By beta (market sensitivity over 5 years), Immunovant, Inc.
(IMVT) is the lower-risk stock at 1. 37β versus ALX Oncology Holdings Inc. 's 1. 44β — meaning ALXO is approximately 5% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 15% for ALX Oncology Holdings Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — ALXO or IMVT?
On earnings-per-share growth, the picture is similar: ALX Oncology Holdings Inc.
grew EPS 31. 0% year-over-year, compared to -45. 2% for Immunovant, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ALXO or IMVT?
ALX Oncology Holdings Inc.
(ALXO) is the more profitable company, earning 0. 0% net margin versus 0. 0% for Immunovant, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ALXO leads at 0. 0% versus 0. 0% for IMVT. At the gross margin level — before operating expenses — ALXO leads at 0. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — ALXO or IMVT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is ALXO or IMVT better for a retirement portfolio?
For long-horizon retirement investors, Immunovant, Inc.
(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+188. 1% 10Y return). Both have compounded well over 10 years (IMVT: +188. 1%, ALXO: -93. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between ALXO and IMVT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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