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ANIK vs MDXG vs NVCR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Medical - Instruments & Supplies
ANIK vs MDXG vs NVCR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||
|---|---|---|---|
| Industry | Medical - Devices | Biotechnology | Medical - Instruments & Supplies |
| Market Cap | $203M | $548M | $1.92B |
| Revenue (TTM) | $116M | $389M | $674M |
| Net Income (TTM) | $-11M | $31M | $-173M |
| Gross Margin | 58.6% | 81.0% | 75.2% |
| Operating Margin | -10.5% | 10.2% | -27.2% |
| Forward P/E | — | 295.2x | — |
| Total Debt | $24M | $23M | $290M |
| Cash & Equiv. | $57M | $166M | $103M |
ANIK vs MDXG vs NVCR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Anika Therapeutics,… (ANIK) | 100 | 45.2 | -54.8% |
| MiMedx Group, Inc. (MDXG) | 100 | 102.8 | +2.8% |
| NovoCure Limited (NVCR) | 100 | 25.0 | -75.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ANIK vs MDXG vs NVCR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ANIK is the clearest fit if your priority is income & stability and sleep-well-at-night.
- beta 1.14
- Lower volatility, beta 1.14, Low D/E 16.9%, current ratio 4.72x
- Beta 1.14, current ratio 4.72x
MDXG carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 20.0%, EPS growth 14.3%, 3Y rev CAGR 16.1%
- -48.5% 10Y total return vs NVCR's 30.3%
- 20.0% revenue growth vs ANIK's -5.9%
NVCR plays a supporting role in this comparison — it may shine differently against other peers.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 20.0% revenue growth vs ANIK's -5.9% | |
| Value | Better valuation composite | |
| Quality / Margins | 7.9% margin vs NVCR's -25.7% | |
| Stability / Safety | Beta 1.14 vs NVCR's 2.20, lower leverage | |
| Dividends | Tie | None of these 3 stocks pay a meaningful dividend |
| Momentum (1Y) | +4.5% vs MDXG's -47.1% | |
| Efficiency (ROA) | 9.7% ROA vs NVCR's -16.5%, ROIC 42.3% vs -16.4% |
ANIK vs MDXG vs NVCR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
ANIK vs MDXG vs NVCR — Financial Metrics
Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
MDXG leads in 3 of 6 categories
ANIK leads 1 • NVCR leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
MDXG leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVCR is the larger business by revenue, generating $674M annually — 5.8x ANIK's $116M. MDXG is the more profitable business, keeping 7.9% of every revenue dollar as net income compared to NVCR's -25.7%. On growth, ANIK holds the edge at +13.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||
|---|---|---|---|
| RevenueTrailing 12 months | $116M | $389M | $674M |
| EBITDAEarnings before interest/tax | -$7M | $53M | -$165M |
| Net IncomeAfter-tax profit | -$11M | $31M | -$173M |
| Free Cash FlowCash after capex | $1M | $66M | -$48M |
| Gross MarginGross profit ÷ Revenue | +58.6% | +81.0% | +75.2% |
| Operating MarginEBIT ÷ Revenue | -10.5% | +10.2% | -27.2% |
| Net MarginNet income ÷ Revenue | -9.5% | +7.9% | -25.7% |
| FCF MarginFCF ÷ Revenue | +0.9% | +17.0% | -7.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | +13.2% | -33.1% | +12.3% |
| EPS Growth (YoY)Latest quarter vs prior year | -8.8% | -2.4% | -100.0% |
Valuation Metrics
Evenly matched — ANIK and MDXG each lead in 2 of 4 comparable metrics.
Valuation Metrics
| Metric | |||
|---|---|---|---|
| Market CapShares × price | $203M | $548M | $1.9B |
| Enterprise ValueMkt cap + debt − cash | $170M | $405M | $2.1B |
| Trailing P/EPrice ÷ TTM EPS | -19.92x | 11.53x | -13.80x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 295.20x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — |
| EV / EBITDAEnterprise value multiple | — | 5.14x | — |
| Price / SalesMarket cap ÷ Revenue | 1.80x | 1.31x | 2.92x |
| Price / BookPrice ÷ Book value/share | 1.51x | 2.15x | 5.51x |
| Price / FCFMarket cap ÷ FCF | 46.51x | 7.51x | — |
Profitability & Efficiency
MDXG leads this category, winning 8 of 9 comparable metrics.
Profitability & Efficiency
MDXG delivers a 12.9% return on equity — every $100 of shareholder capital generates $13 in annual profit, vs $-51 for NVCR. MDXG carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), ANIK scores 6/9 vs NVCR's 5/9, reflecting solid financial health.
| Metric | |||
|---|---|---|---|
| ROE (TTM)Return on equity | -7.7% | +12.9% | -50.8% |
| ROA (TTM)Return on assets | -5.9% | +9.7% | -16.5% |
| ROICReturn on invested capital | -7.1% | +42.3% | -16.4% |
| ROCEReturn on capital employed | -6.4% | +25.7% | -28.9% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 5 | 5 |
| Debt / EquityFinancial leverage | 0.17x | 0.09x | 0.85x |
| Net DebtTotal debt minus cash | -$33M | -$144M | $187M |
| Cash & Equiv.Liquid assets | $57M | $166M | $103M |
| Total DebtShort + long-term debt | $24M | $23M | $290M |
| Interest CoverageEBIT ÷ Interest expense | — | 25.32x | -96.80x |
Total Returns (Dividends Reinvested)
MDXG leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in MDXG five years ago would be worth $3,712 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, ANIK leads with a +4.5% total return vs MDXG's -47.1%. The 3-year compound annual growth rate (CAGR) favors MDXG at -14.1% vs NVCR's -37.6% — a key indicator of consistent wealth creation.
| Metric | |||
|---|---|---|---|
| YTD ReturnYear-to-date | +61.9% | -43.1% | +28.3% |
| 1-Year ReturnPast 12 months | +4.5% | -47.1% | +1.1% |
| 3-Year ReturnCumulative with dividends | -41.7% | -36.6% | -75.7% |
| 5-Year ReturnCumulative with dividends | -63.9% | -62.9% | -91.3% |
| 10-Year ReturnCumulative with dividends | -65.9% | -48.5% | +30.3% |
| CAGR (3Y)Annualised 3-year return | -16.5% | -14.1% | -37.6% |
Risk & Volatility
ANIK leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
ANIK is the less volatile stock with a 1.14 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ANIK currently trades 93.2% from its 52-week high vs MDXG's 46.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||
|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.14x | 1.22x | 2.20x |
| 52-Week HighHighest price in past year | $16.24 | $7.99 | $20.06 |
| 52-Week LowLowest price in past year | $7.87 | $3.02 | $9.82 |
| % of 52W HighCurrent price vs 52-week peak | +93.2% | +46.2% | +83.9% |
| RSI (14)Momentum oscillator 0–100 | 53.3 | 49.3 | 69.8 |
| Avg Volume (50D)Average daily shares traded | 135K | 1.4M | 1.5M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: ANIK as "Buy", MDXG as "Buy", NVCR as "Buy". Consensus price targets imply 171.0% upside for MDXG (target: $10) vs 99.0% for NVCR (target: $34).
| Metric | |||
|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $10.00 | $33.50 |
| # AnalystsCovering analysts | 6 | 15 | 15 |
| Dividend YieldAnnual dividend ÷ price | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +4.7% | +0.6% | 0.0% |
MDXG leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ANIK leads in 1 (Risk & Volatility). 1 tied.
ANIK vs MDXG vs NVCR: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is ANIK or MDXG or NVCR a better buy right now?
For growth investors, MiMedx Group, Inc.
(MDXG) is the stronger pick with 20. 0% revenue growth year-over-year, versus -5. 9% for Anika Therapeutics, Inc. (ANIK). MiMedx Group, Inc. (MDXG) offers the better valuation at 11. 5x trailing P/E (295. 2x forward), making it the more compelling value choice. Analysts rate Anika Therapeutics, Inc. (ANIK) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ANIK or MDXG or NVCR?
Over the past 5 years, MiMedx Group, Inc.
(MDXG) delivered a total return of -62. 9%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: NVCR returned +30. 3% versus ANIK's -65. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ANIK or MDXG or NVCR?
By beta (market sensitivity over 5 years), Anika Therapeutics, Inc.
(ANIK) is the lower-risk stock at 1. 14β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 93% more volatile than ANIK relative to the S&P 500. On balance sheet safety, MiMedx Group, Inc. (MDXG) carries a lower debt/equity ratio of 9% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.
04Which is growing faster — ANIK or MDXG or NVCR?
By revenue growth (latest reported year), MiMedx Group, Inc.
(MDXG) is pulling ahead at 20. 0% versus -5. 9% for Anika Therapeutics, Inc. (ANIK). On earnings-per-share growth, the picture is similar: Anika Therapeutics, Inc. grew EPS 80. 2% year-over-year, compared to 14. 3% for MiMedx Group, Inc.. Over a 3-year CAGR, MDXG leads at 16. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ANIK or MDXG or NVCR?
MiMedx Group, Inc.
(MDXG) is the more profitable company, earning 11. 6% net margin versus -20. 8% for NovoCure Limited — meaning it keeps 11. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MDXG leads at 15. 3% versus -23. 5% for NVCR. At the gross margin level — before operating expenses — MDXG leads at 82. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is ANIK or MDXG or NVCR more undervalued right now?
Analyst consensus price targets imply the most upside for MDXG: 171.
0% to $10. 00.
07Which pays a better dividend — ANIK or MDXG or NVCR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is ANIK or MDXG or NVCR better for a retirement portfolio?
For long-horizon retirement investors, Anika Therapeutics, Inc.
(ANIK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 14)). NovoCure Limited (NVCR) carries a higher beta of 2. 20 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ANIK: -65. 9%, NVCR: +30. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between ANIK and MDXG and NVCR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ANIK is a small-cap quality compounder stock; MDXG is a small-cap high-growth stock; NVCR is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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