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NVCR vs NKTR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
NVCR vs NKTR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Medical - Instruments & Supplies | Biotechnology |
| Market Cap | $1.81B | $1.65B |
| Revenue (TTM) | $674M | $63M |
| Net Income (TTM) | $-173M | $-121M |
| Gross Margin | 75.2% | 86.9% |
| Operating Margin | -27.2% | -156.5% |
| Total Debt | $290M | $86M |
| Cash & Equiv. | $103M | $15M |
NVCR vs NKTR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| NovoCure Limited (NVCR) | 100 | 23.6 | -76.4% |
| Nektar Therapeutics (NKTR) | 100 | 25.9 | -74.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: NVCR vs NKTR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
NVCR carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 8.3%, EPS growth 21.8%, 3Y rev CAGR 6.8%
- 40.0% 10Y total return vs NKTR's -58.9%
- 8.3% revenue growth vs NKTR's -43.9%
NKTR is the clearest fit if your priority is income & stability and sleep-well-at-night.
- beta 1.85
- Lower volatility, beta 1.85, Low D/E 95.5%, current ratio 4.97x
- Beta 1.85, current ratio 4.97x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.3% revenue growth vs NKTR's -43.9% | |
| Quality / Margins | -25.7% margin vs NKTR's -192.9% | |
| Stability / Safety | Beta 1.85 vs NVCR's 2.20 | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +7.2% vs NVCR's -10.6% | |
| Efficiency (ROA) | -16.5% ROA vs NKTR's -45.2%, ROIC -16.4% vs -75.2% |
NVCR vs NKTR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
NVCR vs NKTR — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
NVCR leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVCR is the larger business by revenue, generating $674M annually — 10.8x NKTR's $63M. NVCR is the more profitable business, keeping -25.7% of every revenue dollar as net income compared to NKTR's -192.9%. On growth, NVCR holds the edge at +12.3% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $674M | $63M |
| EBITDAEarnings before interest/tax | -$165M | -$97M |
| Net IncomeAfter-tax profit | -$173M | -$121M |
| Free Cash FlowCash after capex | -$48M | -$190M |
| Gross MarginGross profit ÷ Revenue | +75.2% | +86.9% |
| Operating MarginEBIT ÷ Revenue | -27.2% | -156.5% |
| Net MarginNet income ÷ Revenue | -25.7% | -192.9% |
| FCF MarginFCF ÷ Revenue | -7.1% | -3.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | +12.3% | -51.1% |
| EPS Growth (YoY)Latest quarter vs prior year | -100.0% | +29.7% |
Valuation Metrics
NVCR leads this category, winning 3 of 3 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $1.8B | $1.7B |
| Enterprise ValueMkt cap + debt − cash | $2.0B | $1.7B |
| Trailing P/EPrice ÷ TTM EPS | -13.02x | -8.65x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 2.76x | 29.95x |
| Price / BookPrice ÷ Book value/share | 5.20x | 15.81x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
NVCR leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
NVCR delivers a -50.8% return on equity — every $100 of shareholder capital generates $-51 in annual profit, vs $-4 for NKTR. NVCR carries lower financial leverage with a 0.85x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 0.95x. On the Piotroski fundamental quality scale (0–9), NVCR scores 5/9 vs NKTR's 2/9, reflecting solid financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -50.8% | -3.6% |
| ROA (TTM)Return on assets | -16.5% | -45.2% |
| ROICReturn on invested capital | -16.4% | -75.2% |
| ROCEReturn on capital employed | -28.9% | -59.7% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 2 |
| Debt / EquityFinancial leverage | 0.85x | 0.95x |
| Net DebtTotal debt minus cash | $187M | $71M |
| Cash & Equiv.Liquid assets | $103M | $15M |
| Total DebtShort + long-term debt | $290M | $86M |
| Interest CoverageEBIT ÷ Interest expense | -96.80x | -3.30x |
Total Returns (Dividends Reinvested)
NKTR leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in NKTR five years ago would be worth $3,004 today (with dividends reinvested), compared to $787 for NVCR. Over the past 12 months, NKTR leads with a +716.3% total return vs NVCR's -10.6%. The 3-year compound annual growth rate (CAGR) favors NKTR at 89.8% vs NVCR's -38.5% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +21.0% | +93.8% |
| 1-Year ReturnPast 12 months | -10.6% | +716.3% |
| 3-Year ReturnCumulative with dividends | -76.7% | +584.2% |
| 5-Year ReturnCumulative with dividends | -92.1% | -70.0% |
| 10-Year ReturnCumulative with dividends | +40.0% | -58.9% |
| CAGR (3Y)Annualised 3-year return | -38.5% | +89.8% |
Risk & Volatility
Evenly matched — NVCR and NKTR each lead in 1 of 2 comparable metrics.
Risk & Volatility
NKTR is the less volatile stock with a 1.85 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.20x | 1.85x |
| 52-Week HighHighest price in past year | $20.06 | $109.00 |
| 52-Week LowLowest price in past year | $9.82 | $7.99 |
| % of 52W HighCurrent price vs 52-week peak | +79.2% | +77.2% |
| RSI (14)Momentum oscillator 0–100 | 76.7 | 56.5 |
| Avg Volume (50D)Average daily shares traded | 1.6M | 1.0M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates NVCR as "Buy" and NKTR as "Buy". Consensus price targets imply 111.0% upside for NVCR (target: $34) vs 57.8% for NKTR (target: $133).
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $33.50 | $132.83 |
| # AnalystsCovering analysts | 15 | 33 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
NVCR leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). NKTR leads in 1 (Total Returns). 1 tied.
NVCR vs NKTR: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is NVCR or NKTR a better buy right now?
For growth investors, NovoCure Limited (NVCR) is the stronger pick with 8.
3% revenue growth year-over-year, versus -43. 9% for Nektar Therapeutics (NKTR). Analysts rate NovoCure Limited (NVCR) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — NVCR or NKTR?
Over the past 5 years, Nektar Therapeutics (NKTR) delivered a total return of -70.
0%, compared to -92. 1% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: NVCR returned +40. 0% versus NKTR's -58. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — NVCR or NKTR?
By beta (market sensitivity over 5 years), Nektar Therapeutics (NKTR) is the lower-risk stock at 1.
85β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 19% more volatile than NKTR relative to the S&P 500. On balance sheet safety, NovoCure Limited (NVCR) carries a lower debt/equity ratio of 85% versus 95% for Nektar Therapeutics — giving it more financial flexibility in a downturn.
04Which is growing faster — NVCR or NKTR?
By revenue growth (latest reported year), NovoCure Limited (NVCR) is pulling ahead at 8.
3% versus -43. 9% for Nektar Therapeutics (NKTR). On earnings-per-share growth, the picture is similar: NovoCure Limited grew EPS 21. 8% year-over-year, compared to -12. 1% for Nektar Therapeutics. Over a 3-year CAGR, NVCR leads at 6. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — NVCR or NKTR?
NovoCure Limited (NVCR) is the more profitable company, earning -20.
8% net margin versus -297. 1% for Nektar Therapeutics — meaning it keeps -20. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVCR leads at -23. 5% versus -253. 7% for NKTR. At the gross margin level — before operating expenses — NKTR leads at 86. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — NVCR or NKTR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is NVCR or NKTR better for a retirement portfolio?
For long-horizon retirement investors, Nektar Therapeutics (NKTR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding.
NovoCure Limited (NVCR) carries a higher beta of 2. 20 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (NKTR: -58. 9%, NVCR: +40. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between NVCR and NKTR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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