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PFE
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Stock Comparison

ANL vs ABBV vs JPM vs MRK vs PFE

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ANL
Adlai Nortye Ltd.

Biotechnology

HealthcareNASDAQ • KY
Market Cap$322M
5Y Perf.-31.2%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$402.80B
5Y Perf.+52.8%
JPM
JPMorgan Chase & Co.

Banks - Diversified

Financial ServicesNYSE • US
Market Cap$896.00B
5Y Perf.+121.2%
MRK
Merck & Co., Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$294.04B
5Y Perf.+15.6%
PFE
Pfizer Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$149.09B
5Y Perf.-21.0%

ANL vs ABBV vs JPM vs MRK vs PFE — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ANL logoANL
ABBV logoABBV
JPM logoJPM
MRK logoMRK
PFE logoPFE
IndustryBiotechnologyDrug Manufacturers - GeneralBanks - DiversifiedDrug Manufacturers - GeneralDrug Manufacturers - General
Market Cap$322M$402.80B$896.00B$294.04B$149.09B
Revenue (TTM)$6M$61.16B$280.33B$64.93B$63.31B
Net Income (TTM)$-54M$4.23B$57.05B$18.25B$7.49B
Gross Margin100.0%70.2%60.0%74.2%69.3%
Operating Margin-10.0%26.7%25.9%41.1%23.4%
Forward P/E16.0x14.4x23.2x8.9x
Total Debt$27M$69.07B$942.38B$50.53B$67.42B
Cash & Equiv.$61M$5.23B$343.34B$14.56B$1.14B

ANL vs ABBV vs JPM vs MRK vs PFELong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ANL
ABBV
JPM
MRK
PFE
StockSep 23Jun 26Return
Adlai Nortye Ltd. (ANL)10068.8-31.2%
AbbVie Inc. (ABBV)100152.8+52.8%
JPMorgan Chase & Co. (JPM)100221.2+121.2%
Merck & Co., Inc. (MRK)100115.6+15.6%
Pfizer Inc. (PFE)10079.0-21.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: ANL vs ABBV vs JPM vs MRK vs PFE

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ABBV and MRK are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Merck & Co., Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. ANL, JPM, and PFE also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
ANL
Adlai Nortye Ltd.
The Momentum Pick

ANL ranks third and is worth considering specifically for momentum.

  • +5.5% vs PFE's +12.4%
Best for: momentum
ABBV
AbbVie Inc.
The Income Pick

ABBV has the current edge in this matchup, primarily because of its strength in income & stability and growth exposure.

  • Dividend streak 43 yrs, beta 0.14, yield 2.9%
  • Rev growth 8.6%, EPS growth -0.8%, 3Y rev CAGR 1.8%
  • 8.6% revenue growth vs ANL's -100.0%
  • Beta 0.14 vs ANL's 1.39
Best for: income & stability and growth exposure
JPM
JPMorgan Chase & Co.
The Banking Pick

JPM is the clearest fit if your priority is long-term compounding and valuation efficiency.

  • 465.8% 10Y total return vs ABBV's 362.2%
  • PEG 0.81 vs MRK's 1.09
  • Lower P/E (14.4x vs 23.2x), PEG 0.81 vs 1.09
Best for: long-term compounding and valuation efficiency
MRK
Merck & Co., Inc.
The Defensive Pick

MRK is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.

  • Lower volatility, beta 0.32, Low D/E 96.0%, current ratio 1.54x
  • Beta 0.32, yield 2.7%, current ratio 1.54x
  • 28.1% margin vs ANL's -8.3%
  • 14.6% ROA vs ANL's -50.2%, ROIC 22.0% vs -7.3%
Best for: sleep-well-at-night and defensive
PFE
Pfizer Inc.
The Income Pick

PFE is the clearest fit if your priority is dividends.

  • 6.6% yield, 15-year raise streak, vs ABBV's 2.9%, (1 stock pays no dividend)
Best for: dividends
See the full category breakdown
CategoryWinnerWhy
GrowthABBV logoABBV8.6% revenue growth vs ANL's -100.0%
ValueJPM logoJPMLower P/E (14.4x vs 23.2x), PEG 0.81 vs 1.09
Quality / MarginsMRK logoMRK28.1% margin vs ANL's -8.3%
Stability / SafetyABBV logoABBVBeta 0.14 vs ANL's 1.39
DividendsPFE logoPFE6.6% yield, 15-year raise streak, vs ABBV's 2.9%, (1 stock pays no dividend)
Momentum (1Y)ANL logoANL+5.5% vs PFE's +12.4%
Efficiency (ROA)MRK logoMRK14.6% ROA vs ANL's -50.2%, ROIC 22.0% vs -7.3%

ANL vs ABBV vs JPM vs MRK vs PFE — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

Discover the Biotech & Healthcare Stocks Theme

These companies are key players in the Biotech & Healthcare Stocks ecosystem. See how they stack up against the rest of the sector.

Explore Theme
ANLAdlai Nortye Ltd.

Segment breakdown not available.

ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B
JPMJPMorgan Chase & Co.
FY 2025
Commercial And Investment Bank
43.0%$78.5B
Consumer & Community Banking
41.7%$76.0B
Asset and Wealth Management Segment
13.2%$24.1B
Segment Reporting, Reconciling Item, Corporate Nonsegment
3.9%$7.0B
Segment Reconciling Items
-1.7%$-3,134,000,000
MRKMerck & Co., Inc.
FY 2025
Pharmaceutical segment
89.4%$58.1B
Animal Health segment
9.8%$6.4B
Other Segments
0.8%$515M
PFEPfizer Inc.
FY 2025
Biopharma Segment
97.8%$61.2B
Segment Reporting, Reconciling Item, Corporate Nonsegment
2.2%$1.4B

ANL vs ABBV vs JPM vs MRK vs PFE — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLJPMLAGGINGABBV

Income & Cash Flow (Last 12 Months)

Evenly matched — ABBV and MRK each lead in 2 of 6 comparable metrics.

JPM is the larger business by revenue, generating $280.3B annually — 43194.6x ANL's $6M. MRK is the more profitable business, keeping 28.1% of every revenue dollar as net income compared to ANL's -8.3%. On growth, ABBV holds the edge at +10.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricANL logoANLAdlai Nortye Ltd.ABBV logoABBVAbbVie Inc.JPM logoJPMJPMorgan Chase & …MRK logoMRKMerck & Co., Inc.PFE logoPFEPfizer Inc.
RevenueTrailing 12 months$6M$61.2B$280.3B$64.9B$63.3B
EBITDAEarnings before interest/tax-$64M$24.5B$81.4B$32.4B$21.0B
Net IncomeAfter-tax profit-$54M$4.2B$57.0B$18.3B$7.5B
Free Cash FlowCash after capex-$67M$18.7B$100.9B$12.4B$9.5B
Gross MarginGross profit ÷ Revenue+100.0%+70.2%+60.0%+74.2%+69.3%
Operating MarginEBIT ÷ Revenue-10.0%+26.7%+25.9%+41.1%+23.4%
Net MarginNet income ÷ Revenue-8.3%+6.9%+20.4%+28.1%+11.8%
FCF MarginFCF ÷ Revenue-10.3%+30.6%+36.0%+19.0%+15.0%
Rev. Growth (YoY)Latest quarter vs prior year+10.0%+4.5%+5.4%
EPS Growth (YoY)Latest quarter vs prior year+78.7%+57.4%+16.0%-19.6%-9.5%
Evenly matched — ABBV and MRK each lead in 2 of 6 comparable metrics.

Valuation Metrics

PFE leads this category, winning 4 of 7 comparable metrics.

At 16.0x trailing earnings, JPM trades at a 83% valuation discount to ABBV's 96.1x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.77x vs JPM's 0.90x — a lower PEG means you pay less per unit of expected earnings growth.

MetricANL logoANLAdlai Nortye Ltd.ABBV logoABBVAbbVie Inc.JPM logoJPMJPMorgan Chase & …MRK logoMRKMerck & Co., Inc.PFE logoPFEPfizer Inc.
Market CapShares × price$322M$402.8B$896.0B$294.0B$149.1B
Enterprise ValueMkt cap + debt − cash$289M$466.6B$1.50T$330.0B$215.4B
Trailing P/EPrice ÷ TTM EPS-2.11x96.09x16.00x16.35x19.27x
Forward P/EPrice ÷ next-FY EPS est.15.96x14.40x23.17x8.85x
PEG RatioP/E ÷ EPS growth rate0.90x0.77x
EV / EBITDAEnterprise value multiple16.53x18.36x11.25x10.59x
Price / SalesMarket cap ÷ Revenue6.59x3.20x4.53x2.38x
Price / BookPrice ÷ Book value/share4.31x2.47x5.67x1.72x
Price / FCFMarket cap ÷ FCF22.61x8.88x23.79x16.43x
PFE leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

MRK leads this category, winning 3 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-101 for ANL. PFE carries lower financial leverage with a 0.78x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), PFE scores 7/9 vs ANL's 2/9, reflecting strong financial health.

MetricANL logoANLAdlai Nortye Ltd.ABBV logoABBVAbbVie Inc.JPM logoJPMJPMorgan Chase & …MRK logoMRKMerck & Co., Inc.PFE logoPFEPfizer Inc.
ROE (TTM)Return on equity-101.3%+62.1%+15.9%+36.1%+8.3%
ROA (TTM)Return on assets-50.2%+3.1%+1.3%+14.6%+3.6%
ROICReturn on invested capital-7.3%+23.9%+4.5%+22.0%+7.5%
ROCEReturn on capital employed-103.8%+21.5%+8.9%+23.8%+9.0%
Piotroski ScoreFundamental quality 0–926547
Debt / EquityFinancial leverage1.07x2.60x0.96x0.78x
Net DebtTotal debt minus cash-$34M$63.8B$599.0B$36.0B$66.3B
Cash & Equiv.Liquid assets$61M$5.2B$343.3B$14.6B$1.1B
Total DebtShort + long-term debt$27M$69.1B$942.4B$50.5B$67.4B
Interest CoverageEBIT ÷ Interest expense-28.22x3.28x0.74x19.68x4.02x
MRK leads this category, winning 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

JPM leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in ABBV five years ago would be worth $22,367 today (with dividends reinvested), compared to $6,880 for ANL. Over the past 12 months, ANL leads with a +545.0% total return vs PFE's +12.4%. The 3-year compound annual growth rate (CAGR) favors JPM at 33.6% vs ANL's -11.7% — a key indicator of consistent wealth creation.

MetricANL logoANLAdlai Nortye Ltd.ABBV logoABBVAbbVie Inc.JPM logoJPMJPMorgan Chase & …MRK logoMRKMerck & Co., Inc.PFE logoPFEPfizer Inc.
YTD ReturnYear-to-date+647.8%+0.8%-0.5%+12.6%+7.5%
1-Year ReturnPast 12 months+545.0%+21.9%+21.8%+49.6%+12.4%
3-Year ReturnCumulative with dividends-31.2%+79.3%+138.2%+17.0%-21.6%
5-Year ReturnCumulative with dividends-31.2%+123.7%+118.2%+77.7%-13.0%
10-Year ReturnCumulative with dividends-31.2%+362.2%+465.8%+169.6%+25.8%
CAGR (3Y)Annualised 3-year return-11.7%+21.5%+33.6%+5.4%-7.8%
JPM leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ABBV and MRK each lead in 1 of 2 comparable metrics.

ABBV is the less volatile stock with a 0.14 beta — it tends to amplify market swings less than ANL's 1.39 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRK currently trades 95.1% from its 52-week high vs ANL's 59.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricANL logoANLAdlai Nortye Ltd.ABBV logoABBVAbbVie Inc.JPM logoJPMJPMorgan Chase & …MRK logoMRKMerck & Co., Inc.PFE logoPFEPfizer Inc.
Beta (5Y)Sensitivity to S&P 5001.39x0.14x0.94x0.32x0.38x
52-Week HighHighest price in past year$17.25$244.81$337.25$125.14$28.75
52-Week LowLowest price in past year$0.88$181.73$262.71$76.66$23.11
% of 52W HighCurrent price vs 52-week peak+59.8%+93.0%+95.1%+95.1%+91.2%
RSI (14)Momentum oscillator 0–10039.062.859.158.953.2
Avg Volume (50D)Average daily shares traded380K4.6M7.0M7.2M28.5M
Evenly matched — ABBV and MRK each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — ABBV and PFE each lead in 1 of 2 comparable metrics.

Analyst consensus: ANL as "Buy", ABBV as "Buy", JPM as "Buy", MRK as "Buy", PFE as "Hold". Consensus price targets imply 151.9% upside for ANL (target: $26) vs 2.1% for PFE (target: $27). For income investors, PFE offers the higher dividend yield at 6.56% vs JPM's 1.86%.

MetricANL logoANLAdlai Nortye Ltd.ABBV logoABBVAbbVie Inc.JPM logoJPMJPMorgan Chase & …MRK logoMRKMerck & Co., Inc.PFE logoPFEPfizer Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyHold
Price TargetConsensus 12-month target$26.00$256.92$339.75$131.58$26.75
# AnalystsCovering analysts141613739
Dividend YieldAnnual dividend ÷ price+2.9%+1.9%+2.7%+6.6%
Dividend StreakConsecutive years of raises43151515
Dividend / ShareAnnual DPS$6.57$5.95$3.26$1.72
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.2%+3.9%+1.7%0.0%
Evenly matched — ABBV and PFE each lead in 1 of 2 comparable metrics.
Key Takeaway

PFE leads in 1 of 6 categories (Valuation Metrics). MRK leads in 1 (Profitability & Efficiency). 3 tied.

Best OverallJPMorgan Chase & Co. (JPM)Leads 1 of 6 categories
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ANL vs ABBV vs JPM vs MRK vs PFE: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ANL or ABBV or JPM or MRK or PFE a better buy right now?

For growth investors, AbbVie Inc.

(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -100. 0% for Adlai Nortye Ltd. (ANL). JPMorgan Chase & Co. (JPM) offers the better valuation at 16. 0x trailing P/E (14. 4x forward), making it the more compelling value choice. Analysts rate Adlai Nortye Ltd. (ANL) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ANL or ABBV or JPM or MRK or PFE?

On trailing P/E, JPMorgan Chase & Co.

(JPM) is the cheapest at 16. 0x versus AbbVie Inc. at 96. 1x. On forward P/E, Pfizer Inc. is actually cheaper at 8. 9x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: JPMorgan Chase & Co. wins at 0. 81x versus Merck & Co. , Inc. 's 1. 09x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — ANL or ABBV or JPM or MRK or PFE?

Over the past 5 years, AbbVie Inc.

(ABBV) delivered a total return of +123. 7%, compared to -31. 2% for Adlai Nortye Ltd. (ANL). Over 10 years, the gap is even starker: JPM returned +465. 8% versus ANL's -31. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ANL or ABBV or JPM or MRK or PFE?

By beta (market sensitivity over 5 years), AbbVie Inc.

(ABBV) is the lower-risk stock at 0. 14β versus Adlai Nortye Ltd. 's 1. 39β — meaning ANL is approximately 923% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Pfizer Inc. (PFE) carries a lower debt/equity ratio of 78% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.

05

Which is growing faster — ANL or ABBV or JPM or MRK or PFE?

By revenue growth (latest reported year), AbbVie Inc.

(ABBV) is pulling ahead at 8. 6% versus -100. 0% for Adlai Nortye Ltd. (ANL). On earnings-per-share growth, the picture is similar: Adlai Nortye Ltd. grew EPS 68. 3% year-over-year, compared to -3. 5% for Pfizer Inc.. Over a 3-year CAGR, MRK leads at 3. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ANL or ABBV or JPM or MRK or PFE?

Merck & Co.

, Inc. (MRK) is the more profitable company, earning 28. 1% net margin versus -833. 1% for Adlai Nortye Ltd. — meaning it keeps 28. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 36. 2% versus -996. 4% for ANL. At the gross margin level — before operating expenses — ANL leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ANL or ABBV or JPM or MRK or PFE more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, JPMorgan Chase & Co. (JPM) is the more undervalued stock at a PEG of 0. 81x versus Merck & Co. , Inc. 's 1. 09x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Pfizer Inc. (PFE) trades at 8. 9x forward P/E versus 23. 2x for Merck & Co. , Inc. — 14. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ANL: 151. 9% to $26. 00.

08

Which pays a better dividend — ANL or ABBV or JPM or MRK or PFE?

In this comparison, PFE (6.

6% yield), ABBV (2. 9% yield), MRK (2. 7% yield), JPM (1. 9% yield) pay a dividend. ANL does not pay a meaningful dividend and should not be held primarily for income.

09

Is ANL or ABBV or JPM or MRK or PFE better for a retirement portfolio?

For long-horizon retirement investors, AbbVie Inc.

(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 14), 2. 9% yield, +362. 2% 10Y return). Both have compounded well over 10 years (ABBV: +362. 2%, ANL: -31. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ANL and ABBV and JPM and MRK and PFE?

These companies operate in different sectors (ANL (Healthcare) and ABBV (Healthcare) and JPM (Financial Services) and MRK (Healthcare) and PFE (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: ANL is a small-cap quality compounder stock; ABBV is a large-cap quality compounder stock; JPM is a large-cap deep-value stock; MRK is a large-cap deep-value stock; PFE is a mid-cap income-oriented stock. ABBV, JPM, MRK, PFE pay a dividend while ANL does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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