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Stock Comparison

APLS vs BCAB

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
APLS
Apellis Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.25B
5Y Perf.-28.3%
BCAB
BioAtla, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5M
5Y Perf.-99.7%

APLS vs BCAB — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
APLS logoAPLS
BCAB logoBCAB
IndustryBiotechnologyBiotechnology
Market Cap$5.25B$5M
Revenue (TTM)$1.03B$2M
Net Income (TTM)$133M$-60M
Gross Margin89.4%100.0%
Operating Margin16.1%-29.7%
Forward P/E227.8x
Total Debt$486M$6M
Cash & Equiv.$468M$7M

APLS vs BCABLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

APLS
BCAB
StockDec 20May 26Return
Apellis Pharmaceuti… (APLS)10071.7-28.3%
BioAtla, Inc. (BCAB)1000.3-99.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: APLS vs BCAB

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: APLS leads in 4 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. BioAtla, Inc. is the stronger pick specifically for capital preservation and lower volatility. As sector peers, any of these can serve as alternatives in the same allocation.
APLS
Apellis Pharmaceuticals, Inc.
The Growth Play

APLS carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.

  • Rev growth 28.5%, EPS growth 111.3%, 3Y rev CAGR 137.0%
  • 192.3% 10Y total return vs BCAB's -99.7%
  • 28.5% revenue growth vs BCAB's -81.8%
Best for: growth exposure and long-term compounding
BCAB
BioAtla, Inc.
The Income Pick

BCAB is the clearest fit if your priority is income & stability and sleep-well-at-night.

  • beta 0.51
  • Lower volatility, beta 0.51, current ratio 0.37x
  • Beta 0.51, current ratio 0.37x
Best for: income & stability and sleep-well-at-night
See the full category breakdown
CategoryWinnerWhy
GrowthAPLS logoAPLS28.5% revenue growth vs BCAB's -81.8%
Quality / MarginsAPLS logoAPLS13.0% margin vs BCAB's -29.8%
Stability / SafetyBCAB logoBCABBeta 0.51 vs APLS's 1.06
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)APLS logoAPLS+128.0% vs BCAB's -80.6%
Efficiency (ROA)APLS logoAPLS13.2% ROA vs BCAB's -250.6%

APLS vs BCAB — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

APLSApellis Pharmaceuticals, Inc.
FY 2025
Product
68.7%$689M
Licensing And Other Revenue
31.3%$314M
BCABBioAtla, Inc.

Segment breakdown not available.

APLS vs BCAB — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLAPLSLAGGINGBCAB

Income & Cash Flow (Last 12 Months)

APLS leads this category, winning 4 of 5 comparable metrics.

APLS is the larger business by revenue, generating $1.0B annually — 514.5x BCAB's $2M. APLS is the more profitable business, keeping 13.0% of every revenue dollar as net income compared to BCAB's -29.8%.

MetricAPLS logoAPLSApellis Pharmaceu…BCAB logoBCABBioAtla, Inc.
RevenueTrailing 12 months$1.0B$2M
EBITDAEarnings before interest/tax$166M-$59M
Net IncomeAfter-tax profit$133M-$60M
Free Cash FlowCash after capex$38M-$34M
Gross MarginGross profit ÷ Revenue+89.4%+100.0%
Operating MarginEBIT ÷ Revenue+16.1%-29.7%
Net MarginNet income ÷ Revenue+13.0%-29.8%
FCF MarginFCF ÷ Revenue+3.7%-17.0%
Rev. Growth (YoY)Latest quarter vs prior year+15.1%
EPS Growth (YoY)Latest quarter vs prior year+100.0%+46.7%
APLS leads this category, winning 4 of 5 comparable metrics.

Valuation Metrics

BCAB leads this category, winning 2 of 2 comparable metrics.
MetricAPLS logoAPLSApellis Pharmaceu…BCAB logoBCABBioAtla, Inc.
Market CapShares × price$5.3B$5M
Enterprise ValueMkt cap + debt − cash$5.3B$4M
Trailing P/EPrice ÷ TTM EPS227.83x-0.09x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple92.46x
Price / SalesMarket cap ÷ Revenue5.23x2.56x
Price / BookPrice ÷ Book value/share13.96x
Price / FCFMarket cap ÷ FCF116.63x
BCAB leads this category, winning 2 of 2 comparable metrics.

Profitability & Efficiency

APLS leads this category, winning 3 of 5 comparable metrics.

On the Piotroski fundamental quality scale (0–9), APLS scores 7/9 vs BCAB's 2/9, reflecting strong financial health.

MetricAPLS logoAPLSApellis Pharmaceu…BCAB logoBCABBioAtla, Inc.
ROE (TTM)Return on equity+39.7%
ROA (TTM)Return on assets+13.2%-2.5%
ROICReturn on invested capital+12.3%
ROCEReturn on capital employed+7.6%-4.0%
Piotroski ScoreFundamental quality 0–972
Debt / EquityFinancial leverage1.31x
Net DebtTotal debt minus cash$19M-$918,000
Cash & Equiv.Liquid assets$468M$7M
Total DebtShort + long-term debt$486M$6M
Interest CoverageEBIT ÷ Interest expense6.50x
APLS leads this category, winning 3 of 5 comparable metrics.

Total Returns (Dividends Reinvested)

APLS leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in APLS five years ago would be worth $8,713 today (with dividends reinvested), compared to $19 for BCAB. Over the past 12 months, APLS leads with a +128.0% total return vs BCAB's -80.6%. The 3-year compound annual growth rate (CAGR) favors APLS at -23.4% vs BCAB's -70.1% — a key indicator of consistent wealth creation.

MetricAPLS logoAPLSApellis Pharmaceu…BCAB logoBCABBioAtla, Inc.
YTD ReturnYear-to-date+58.6%-83.7%
1-Year ReturnPast 12 months+128.0%-80.6%
3-Year ReturnCumulative with dividends-55.1%-97.3%
5-Year ReturnCumulative with dividends-12.9%-99.8%
10-Year ReturnCumulative with dividends+192.3%-99.7%
CAGR (3Y)Annualised 3-year return-23.4%-70.1%
APLS leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

Evenly matched — APLS and BCAB each lead in 1 of 2 comparable metrics.

BCAB is the less volatile stock with a 0.51 beta — it tends to amplify market swings less than APLS's 1.06 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. APLS currently trades 99.7% from its 52-week high vs BCAB's 6.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricAPLS logoAPLSApellis Pharmaceu…BCAB logoBCABBioAtla, Inc.
Beta (5Y)Sensitivity to S&P 5001.06x0.51x
52-Week HighHighest price in past year$41.12$71.50
52-Week LowLowest price in past year$16.10$0.33
% of 52W HighCurrent price vs 52-week peak+99.7%+6.1%
RSI (14)Momentum oscillator 0–10087.240.5
Avg Volume (50D)Average daily shares traded5.4M40K
Evenly matched — APLS and BCAB each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates APLS as "Buy" and BCAB as "Buy". Consensus price targets imply 5647.1% upside for BCAB (target: $250) vs -24.4% for APLS (target: $31).

MetricAPLS logoAPLSApellis Pharmaceu…BCAB logoBCABBioAtla, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$31.00$250.00
# AnalystsCovering analysts259
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

APLS leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BCAB leads in 1 (Valuation Metrics). 1 tied.

Best OverallApellis Pharmaceuticals, In… (APLS)Leads 3 of 6 categories
Loading custom metrics...

APLS vs BCAB: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is APLS or BCAB a better buy right now?

For growth investors, Apellis Pharmaceuticals, Inc.

(APLS) is the stronger pick with 28. 5% revenue growth year-over-year, versus -81. 8% for BioAtla, Inc. (BCAB). Apellis Pharmaceuticals, Inc. (APLS) offers the better valuation at 227. 8x trailing P/E, making it the more compelling value choice. Analysts rate Apellis Pharmaceuticals, Inc. (APLS) a "Buy" — based on 25 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — APLS or BCAB?

Over the past 5 years, Apellis Pharmaceuticals, Inc.

(APLS) delivered a total return of -12. 9%, compared to -99. 8% for BioAtla, Inc. (BCAB). Over 10 years, the gap is even starker: APLS returned +192. 3% versus BCAB's -99. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — APLS or BCAB?

By beta (market sensitivity over 5 years), BioAtla, Inc.

(BCAB) is the lower-risk stock at 0. 51β versus Apellis Pharmaceuticals, Inc. 's 1. 06β — meaning APLS is approximately 109% more volatile than BCAB relative to the S&P 500.

04

Which is growing faster — APLS or BCAB?

By revenue growth (latest reported year), Apellis Pharmaceuticals, Inc.

(APLS) is pulling ahead at 28. 5% versus -81. 8% for BioAtla, Inc. (BCAB). On earnings-per-share growth, the picture is similar: Apellis Pharmaceuticals, Inc. grew EPS 111. 3% year-over-year, compared to 29. 9% for BioAtla, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — APLS or BCAB?

Apellis Pharmaceuticals, Inc.

(APLS) is the more profitable company, earning 2. 2% net margin versus -29. 8% for BioAtla, Inc. — meaning it keeps 2. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: APLS leads at 5. 5% versus -29. 7% for BCAB. At the gross margin level — before operating expenses — BCAB leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — APLS or BCAB?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is APLS or BCAB better for a retirement portfolio?

For long-horizon retirement investors, BioAtla, Inc.

(BCAB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 51)). Both have compounded well over 10 years (BCAB: -99. 7%, APLS: +192. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between APLS and BCAB?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: APLS is a small-cap high-growth stock; BCAB is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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APLS

High-Growth Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 7%
  • Net Margin > 7%
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BCAB

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 60%
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(APLS: 15.1% · BCAB: -81.8%)

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