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Stock Comparison

ATHA vs AVXL

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ATHA
Athira Pharma, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$17M
5Y Perf.-97.6%
AVXL
Anavex Life Sciences Corp.

Biotechnology

HealthcareNASDAQ • US
Market Cap$289M
5Y Perf.+3.3%

ATHA vs AVXL — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ATHA logoATHA
AVXL logoAVXL
IndustryBiotechnologyBiotechnology
Market Cap$17M$289M
Revenue (TTM)$0.00$0.00
Net Income (TTM)$-129M$-40M
Total Debt$803K$0.00
Cash & Equiv.$69M$103M

ATHA vs AVXLLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ATHA
AVXL
StockSep 20Feb 26Return
Athira Pharma, Inc. (ATHA)1002.4-97.6%
Anavex Life Science… (AVXL)100103.3+3.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: ATHA vs AVXL

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ATHA and AVXL are tied at the top with 2 categories each — the right choice depends on your priorities. Anavex Life Sciences Corp. is the stronger pick specifically for growth and revenue expansion and operational efficiency and capital deployment. As sector peers, any of these can serve as alternatives in the same allocation.
ATHA
Athira Pharma, Inc.
The Income Pick

ATHA has the current edge in this matchup, primarily because of its strength in income & stability and growth exposure.

  • beta 1.47
  • EPS growth 2.0%
  • Lower volatility, beta 1.47, Low D/E 2.9%, current ratio 1.88x
Best for: income & stability and growth exposure
AVXL
Anavex Life Sciences Corp.
The Long-Run Compounder

AVXL is the clearest fit if your priority is long-term compounding.

  • -25.7% 10Y total return vs ATHA's -97.5%
  • -34.9% revenue growth vs ATHA's -64.6%
  • -30.0% ROA vs ATHA's -225.7%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthAVXL logoAVXL-34.9% revenue growth vs ATHA's -64.6%
Stability / SafetyATHA logoATHABeta 1.47 vs AVXL's 1.51
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)ATHA logoATHA+81.6% vs AVXL's -63.2%
Efficiency (ROA)AVXL logoAVXL-30.0% ROA vs ATHA's -225.7%

ATHA vs AVXL — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLAVXLLAGGINGATHA

Income & Cash Flow (Last 12 Months)

AVXL leads this category, winning 1 of 1 comparable metric.

ATHA and AVXL operate at a comparable scale, with $0 and $0 in trailing revenue.

MetricATHA logoATHAAthira Pharma, In…AVXL logoAVXLAnavex Life Scien…
RevenueTrailing 12 months$0$0
EBITDAEarnings before interest/tax-$110M-$30M
Net IncomeAfter-tax profit-$129M-$40M
Free Cash FlowCash after capex-$52M-$34M
Gross MarginGross profit ÷ Revenue
Operating MarginEBIT ÷ Revenue
Net MarginNet income ÷ Revenue
FCF MarginFCF ÷ Revenue
Rev. Growth (YoY)Latest quarter vs prior year
EPS Growth (YoY)Latest quarter vs prior year+24.8%+54.4%
AVXL leads this category, winning 1 of 1 comparable metric.

Valuation Metrics

Evenly matched — ATHA and AVXL each lead in 1 of 2 comparable metrics.
MetricATHA logoATHAAthira Pharma, In…AVXL logoAVXLAnavex Life Scien…
Market CapShares × price$17M$289M
Enterprise ValueMkt cap + debt − cash-$30M$187M
Trailing P/EPrice ÷ TTM EPS-0.17x-5.78x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue
Price / BookPrice ÷ Book value/share0.37x2.81x
Price / FCFMarket cap ÷ FCF
Evenly matched — ATHA and AVXL each lead in 1 of 2 comparable metrics.

Profitability & Efficiency

AVXL leads this category, winning 5 of 5 comparable metrics.

AVXL delivers a -31.5% return on equity — every $100 of shareholder capital generates $-32 in annual profit, vs $-4 for ATHA.

MetricATHA logoATHAAthira Pharma, In…AVXL logoAVXLAnavex Life Scien…
ROE (TTM)Return on equity-3.8%-31.5%
ROA (TTM)Return on assets-2.3%-30.0%
ROICReturn on invested capital
ROCEReturn on capital employed-2.3%-47.8%
Piotroski ScoreFundamental quality 0–922
Debt / EquityFinancial leverage0.03x
Net DebtTotal debt minus cash-$68M-$103M
Cash & Equiv.Liquid assets$69M$103M
Total DebtShort + long-term debt$803,000$0
Interest CoverageEBIT ÷ Interest expense
AVXL leads this category, winning 5 of 5 comparable metrics.

Total Returns (Dividends Reinvested)

AVXL leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in AVXL five years ago would be worth $2,759 today (with dividends reinvested), compared to $235 for ATHA. Over the past 12 months, ATHA leads with a +81.6% total return vs AVXL's -63.2%. The 3-year compound annual growth rate (CAGR) favors AVXL at -28.1% vs ATHA's -46.7% — a key indicator of consistent wealth creation.

MetricATHA logoATHAAthira Pharma, In…AVXL logoAVXLAnavex Life Scien…
YTD ReturnYear-to-date-37.6%-15.2%
1-Year ReturnPast 12 months+81.6%-63.2%
3-Year ReturnCumulative with dividends-84.8%-62.9%
5-Year ReturnCumulative with dividends-97.7%-72.4%
10-Year ReturnCumulative with dividends-97.5%-25.7%
CAGR (3Y)Annualised 3-year return-46.7%-28.1%
AVXL leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

ATHA leads this category, winning 2 of 2 comparable metrics.

ATHA is the less volatile stock with a 1.47 beta — it tends to amplify market swings less than AVXL's 1.51 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ATHA currently trades 51.9% from its 52-week high vs AVXL's 22.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricATHA logoATHAAthira Pharma, In…AVXL logoAVXLAnavex Life Scien…
Beta (5Y)Sensitivity to S&P 5001.47x1.51x
52-Week HighHighest price in past year$8.36$13.99
52-Week LowLowest price in past year$2.30$2.61
% of 52W HighCurrent price vs 52-week peak+51.9%+22.3%
RSI (14)Momentum oscillator 0–10038.447.0
Avg Volume (50D)Average daily shares traded46K1.4M
ATHA leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.
MetricATHA logoATHAAthira Pharma, In…AVXL logoAVXLAnavex Life Scien…
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target$11.00
# AnalystsCovering analysts13
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

AVXL leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ATHA leads in 1 (Risk & Volatility). 1 tied.

Best OverallAnavex Life Sciences Corp. (AVXL)Leads 3 of 6 categories
Loading custom metrics...

ATHA vs AVXL: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is ATHA or AVXL a better buy right now?

Analysts rate Anavex Life Sciences Corp.

(AVXL) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — ATHA or AVXL?

Over the past 5 years, Anavex Life Sciences Corp.

(AVXL) delivered a total return of -72. 4%, compared to -97. 7% for Athira Pharma, Inc. (ATHA). Over 10 years, the gap is even starker: AVXL returned -25. 7% versus ATHA's -97. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — ATHA or AVXL?

By beta (market sensitivity over 5 years), Athira Pharma, Inc.

(ATHA) is the lower-risk stock at 1. 47β versus Anavex Life Sciences Corp. 's 1. 51β — meaning AVXL is approximately 3% more volatile than ATHA relative to the S&P 500.

04

Which is growing faster — ATHA or AVXL?

On earnings-per-share growth, the picture is similar: Athira Pharma, Inc.

grew EPS 2. 0% year-over-year, compared to -3. 8% for Anavex Life Sciences Corp.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — ATHA or AVXL?

Athira Pharma, Inc.

(ATHA) is the more profitable company, earning 0. 0% net margin versus 0. 0% for Anavex Life Sciences Corp. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ATHA leads at 0. 0% versus 0. 0% for AVXL. At the gross margin level — before operating expenses — ATHA leads at 0. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — ATHA or AVXL?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is ATHA or AVXL better for a retirement portfolio?

For long-horizon retirement investors, Anavex Life Sciences Corp.

(AVXL) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Both have compounded well over 10 years (AVXL: -25. 7%, ATHA: -97. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between ATHA and AVXL?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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