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AUTL vs DBVT vs CABA vs SANA
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
AUTL vs DBVT vs CABA vs SANA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $410M | $1712.35T | $409M | $918M |
| Revenue (TTM) | $51M | $0.00 | $0.00 | $0.00 |
| Net Income (TTM) | $-225M | $-168M | $-168M | $-234M |
| Gross Margin | -309.4% | — | — | — |
| Operating Margin | -8.6% | — | — | — |
| Total Debt | $53M | $22M | $27M | $94M |
| Cash & Equiv. | $227M | $194M | $83M | $128M |
AUTL vs DBVT vs CABA vs SANA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 21 | May 26 | Return |
|---|---|---|---|
| Autolus Therapeutic… (AUTL) | 100 | 24.9 | -75.1% |
| DBV Technologies S.… (DBVT) | 100 | 37.4 | -62.6% |
| Cabaletta Bio, Inc. (CABA) | 100 | 36.8 | -63.2% |
| Sana Biotechnology,… (SANA) | 100 | 11.4 | -88.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: AUTL vs DBVT vs CABA vs SANA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
AUTL carries the broadest edge in this set and is the clearest fit for growth exposure and sleep-well-at-night.
- Rev growth 496.0%, EPS growth 27.5%, 3Y rev CAGR 88.7%
- Lower volatility, beta 1.95, Low D/E 12.3%, current ratio 10.88x
- 496.0% revenue growth vs DBVT's -100.0%
- -34.0% ROA vs CABA's -90.2%, ROIC -204.1% vs -429.6%
DBVT is the #2 pick in this set and the best alternative if income & stability and defensive is your priority.
- Dividend streak 0 yrs, beta 1.26
- Beta 1.26, current ratio 3.67x
- Beta 1.26 vs SANA's 2.69, lower leverage
CABA is the clearest fit if your priority is long-term compounding.
- -60.0% 10Y total return vs DBVT's -87.0%
- +244.8% vs AUTL's +30.5%
SANA is the clearest fit if your priority is quality.
- 2.1% margin vs AUTL's -439.7%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 496.0% revenue growth vs DBVT's -100.0% | |
| Quality / Margins | 2.1% margin vs AUTL's -439.7% | |
| Stability / Safety | Beta 1.26 vs SANA's 2.69, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +244.8% vs AUTL's +30.5% | |
| Efficiency (ROA) | -34.0% ROA vs CABA's -90.2%, ROIC -204.1% vs -429.6% |
AUTL vs DBVT vs CABA vs SANA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
AUTL vs DBVT vs CABA vs SANA — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
CABA leads in 2 of 6 categories
DBVT leads 1 • AUTL leads 1 • SANA leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
DBVT leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
AUTL and SANA operate at a comparable scale, with $51M and $0 in trailing revenue.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $51M | $0 | $0 | $0 |
| EBITDAEarnings before interest/tax | -$427M | -$112M | -$172M | -$225M |
| Net IncomeAfter-tax profit | -$225M | -$168M | -$168M | -$234M |
| Free Cash FlowCash after capex | -$278M | -$151M | -$132M | -$159M |
| Gross MarginGross profit ÷ Revenue | -3.1% | — | — | — |
| Operating MarginEBIT ÷ Revenue | -8.6% | — | — | — |
| Net MarginNet income ÷ Revenue | -4.4% | — | — | — |
| FCF MarginFCF ÷ Revenue | -5.4% | — | — | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | — | — |
| EPS Growth (YoY)Latest quarter vs prior year | +3.2% | +91.5% | +36.9% | +36.0% |
Valuation Metrics
Evenly matched — DBVT and SANA each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $410M | $1712.35T | $409M | $918M |
| Enterprise ValueMkt cap + debt − cash | $235M | $1712.35T | $353M | $885M |
| Trailing P/EPrice ÷ TTM EPS | -1.84x | -0.76x | -2.44x | -3.02x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 40.47x | — | — | — |
| Price / BookPrice ÷ Book value/share | 0.96x | 0.66x | 3.65x | 3.23x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
AUTL leads this category, winning 7 of 9 comparable metrics.
Profitability & Efficiency
AUTL delivers a -84.7% return on equity — every $100 of shareholder capital generates $-85 in annual profit, vs $-130 for DBVT. AUTL carries lower financial leverage with a 0.12x debt-to-equity ratio, signaling a more conservative balance sheet compared to SANA's 0.38x. On the Piotroski fundamental quality scale (0–9), AUTL scores 5/9 vs CABA's 1/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -84.7% | -130.2% | -121.7% | -120.0% |
| ROA (TTM)Return on assets | -34.0% | -89.0% | -90.2% | -53.8% |
| ROICReturn on invested capital | -2.0% | — | -4.3% | -86.1% |
| ROCEReturn on capital employed | -45.9% | -145.7% | -126.2% | -57.0% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 1 | 2 |
| Debt / EquityFinancial leverage | 0.12x | 0.13x | 0.24x | 0.38x |
| Net DebtTotal debt minus cash | -$175M | -$172M | -$56M | -$33M |
| Cash & Equiv.Liquid assets | $227M | $194M | $83M | $128M |
| Total DebtShort + long-term debt | $53M | $22M | $27M | $94M |
| Interest CoverageEBIT ÷ Interest expense | -25.98x | -189.82x | — | — |
Total Returns (Dividends Reinvested)
CABA leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in CABA five years ago would be worth $4,180 today (with dividends reinvested), compared to $1,926 for SANA. Over the past 12 months, CABA leads with a +244.8% total return vs AUTL's +30.5%. The 3-year compound annual growth rate (CAGR) favors DBVT at 6.2% vs CABA's -30.1% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -14.2% | +4.9% | +81.0% | -16.5% |
| 1-Year ReturnPast 12 months | +30.5% | +110.4% | +244.8% | +105.9% |
| 3-Year ReturnCumulative with dividends | -14.6% | +19.7% | -65.8% | -36.8% |
| 5-Year ReturnCumulative with dividends | -70.1% | -69.1% | -58.2% | -80.7% |
| 10-Year ReturnCumulative with dividends | -93.6% | -87.0% | -60.0% | -90.0% |
| CAGR (3Y)Annualised 3-year return | -5.1% | +6.2% | -30.1% | -14.2% |
Risk & Volatility
Evenly matched — DBVT and CABA each lead in 1 of 2 comparable metrics.
Risk & Volatility
DBVT is the less volatile stock with a 1.26 beta — it tends to amplify market swings less than SANA's 2.69 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CABA currently trades 94.6% from its 52-week high vs SANA's 53.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.95x | 1.26x | 2.54x | 2.69x |
| 52-Week HighHighest price in past year | $2.70 | $26.18 | $4.23 | $6.55 |
| 52-Week LowLowest price in past year | $1.15 | $7.53 | $1.11 | $1.60 |
| % of 52W HighCurrent price vs 52-week peak | +59.4% | +76.3% | +94.6% | +53.4% |
| RSI (14)Momentum oscillator 0–100 | 64.3 | 48.1 | 60.8 | 59.0 |
| Avg Volume (50D)Average daily shares traded | 1.6M | 252K | 2.8M | 3.1M |
Analyst Outlook
CABA leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: AUTL as "Buy", DBVT as "Buy", CABA as "Buy", SANA as "Buy". Consensus price targets imply 452.6% upside for AUTL (target: $9) vs 131.8% for DBVT (target: $46).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $8.87 | $46.33 | $16.33 | $8.67 |
| # AnalystsCovering analysts | 14 | 15 | 12 | 11 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | 0 | 1 | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.1% | 0.0% |
CABA leads in 2 of 6 categories (Total Returns, Analyst Outlook). DBVT leads in 1 (Income & Cash Flow). 2 tied.
AUTL vs DBVT vs CABA vs SANA: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is AUTL or DBVT or CABA or SANA a better buy right now?
Analysts rate Autolus Therapeutics plc (AUTL) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison.
The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — AUTL or DBVT or CABA or SANA?
Over the past 5 years, Cabaletta Bio, Inc.
(CABA) delivered a total return of -58. 2%, compared to -80. 7% for Sana Biotechnology, Inc. (SANA). Over 10 years, the gap is even starker: CABA returned -60. 0% versus AUTL's -93. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — AUTL or DBVT or CABA or SANA?
By beta (market sensitivity over 5 years), DBV Technologies S.
A. (DBVT) is the lower-risk stock at 1. 26β versus Sana Biotechnology, Inc. 's 2. 69β — meaning SANA is approximately 114% more volatile than DBVT relative to the S&P 500. On balance sheet safety, Autolus Therapeutics plc (AUTL) carries a lower debt/equity ratio of 12% versus 38% for Sana Biotechnology, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — AUTL or DBVT or CABA or SANA?
On earnings-per-share growth, the picture is similar: Cabaletta Bio, Inc.
grew EPS 29. 9% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — AUTL or DBVT or CABA or SANA?
DBV Technologies S.
A. (DBVT) is the more profitable company, earning 0. 0% net margin versus -21. 8% for Autolus Therapeutics plc — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DBVT leads at 0. 0% versus -23. 9% for AUTL. At the gross margin level — before operating expenses — DBVT leads at 0. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — AUTL or DBVT or CABA or SANA?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is AUTL or DBVT or CABA or SANA better for a retirement portfolio?
For long-horizon retirement investors, DBV Technologies S.
A. (DBVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 26)). Sana Biotechnology, Inc. (SANA) carries a higher beta of 2. 69 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (DBVT: -87. 0%, SANA: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between AUTL and DBVT and CABA and SANA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: AUTL is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; CABA is a small-cap quality compounder stock; SANA is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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