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AVBP vs NUVL vs KYMR vs ERAS
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
AVBP vs NUVL vs KYMR vs ERAS — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $1.25B | $7.74B | $7.03B | $2.87B |
| Revenue (TTM) | $0.00 | $0.00 | $51M | $0.00 |
| Net Income (TTM) | $-166M | $-450M | $-315M | $-128M |
| Gross Margin | — | — | 33.2% | — |
| Operating Margin | — | — | -7.0% | — |
| Total Debt | $14K | $0.00 | $82M | $52M |
| Cash & Equiv. | $46M | $262M | $357M | $68M |
AVBP vs NUVL vs KYMR vs ERAS — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jan 24 | May 26 | Return |
|---|---|---|---|
| ArriVent BioPharma,… (AVBP) | 100 | 136.9 | +36.9% |
| Nuvalent, Inc. (NUVL) | 100 | 140.1 | +40.1% |
| Kymera Therapeutics… (KYMR) | 100 | 262.6 | +162.6% |
| Erasca, Inc. (ERAS) | 100 | 606.0 | +506.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: AVBP vs NUVL vs KYMR vs ERAS
Each card shows where this stock fits in a portfolio — not just who wins on paper.
AVBP plays a supporting role in this comparison — it may shine differently against other peers.
NUVL is the clearest fit if your priority is long-term compounding and defensive.
- 461.5% 10Y total return vs KYMR's 158.8%
- Beta 1.01, current ratio 15.27x
KYMR is the #2 pick in this set and the best alternative if efficiency is your priority.
- -22.3% ROA vs AVBP's -58.1%
ERAS carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 0.62
- EPS growth 16.9%
- Lower volatility, beta 0.62, Low D/E 12.3%, current ratio 9.84x
- 19.8% revenue growth vs AVBP's -42.5%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 19.8% revenue growth vs AVBP's -42.5% | |
| Quality / Margins | 4.0% margin vs KYMR's -6.1% | |
| Stability / Safety | Beta 0.62 vs AVBP's 1.16 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +6.3% vs NUVL's +47.0% | |
| Efficiency (ROA) | -22.3% ROA vs AVBP's -58.1% |
AVBP vs NUVL vs KYMR vs ERAS — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
KYMR leads in 2 of 6 categories
ERAS leads 1 • AVBP leads 0 • NUVL leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
KYMR leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
KYMR and ERAS operate at a comparable scale, with $51M and $0 in trailing revenue.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $51M | $0 |
| EBITDAEarnings before interest/tax | -$133M | -$346M | -$352M | -$141M |
| Net IncomeAfter-tax profit | -$166M | -$450M | -$315M | -$128M |
| Free Cash FlowCash after capex | -$161M | -$313M | -$244M | -$98M |
| Gross MarginGross profit ÷ Revenue | — | — | +33.2% | — |
| Operating MarginEBIT ÷ Revenue | — | — | -7.0% | — |
| Net MarginNet income ÷ Revenue | — | — | -6.1% | — |
| FCF MarginFCF ÷ Revenue | — | — | -4.7% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | +55.5% | — |
| EPS Growth (YoY)Latest quarter vs prior year | -13.1% | -17.8% | +13.4% | 0.0% |
Valuation Metrics
Evenly matched — AVBP and KYMR each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $1.3B | $7.7B | $7.0B | $2.9B |
| Enterprise ValueMkt cap + debt − cash | $1.2B | $7.5B | $6.8B | $2.9B |
| Trailing P/EPrice ÷ TTM EPS | -6.83x | -18.00x | -23.33x | -14.67x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | — | 179.28x | — |
| Price / BookPrice ÷ Book value/share | 3.69x | 6.13x | 4.60x | 5.59x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
KYMR leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
KYMR delivers a -25.0% return on equity — every $100 of shareholder capital generates $-25 in annual profit, vs $-62 for AVBP. AVBP carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ERAS's 0.12x. On the Piotroski fundamental quality scale (0–9), KYMR scores 4/9 vs NUVL's 1/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -62.5% | -42.8% | -25.0% | -36.7% |
| ROA (TTM)Return on assets | -58.1% | -37.8% | -22.3% | -30.4% |
| ROICReturn on invested capital | — | -32.5% | -24.9% | -39.2% |
| ROCEReturn on capital employed | — | -34.4% | -27.2% | -42.7% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 1 | 4 | 2 |
| Debt / EquityFinancial leverage | 0.00x | — | 0.05x | 0.12x |
| Net DebtTotal debt minus cash | -$46M | -$262M | -$275M | -$16M |
| Cash & Equiv.Liquid assets | $46M | $262M | $357M | $68M |
| Total DebtShort + long-term debt | $14,000 | $0 | $82M | $52M |
| Interest CoverageEBIT ÷ Interest expense | — | -26.85x | -2119.53x | — |
Total Returns (Dividends Reinvested)
ERAS leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in NUVL five years ago would be worth $56,149 today (with dividends reinvested), compared to $5,806 for ERAS. Over the past 12 months, ERAS leads with a +628.1% total return vs NUVL's +47.0%. The 3-year compound annual growth rate (CAGR) favors ERAS at 52.4% vs AVBP's 13.8% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +41.8% | +4.4% | +18.3% | +181.9% |
| 1-Year ReturnPast 12 months | +49.4% | +47.0% | +179.8% | +628.1% |
| 3-Year ReturnCumulative with dividends | +47.5% | +178.8% | +210.3% | +253.8% |
| 5-Year ReturnCumulative with dividends | +47.5% | +461.5% | +95.8% | -41.9% |
| 10-Year ReturnCumulative with dividends | +47.5% | +461.5% | +158.8% | -41.9% |
| CAGR (3Y)Annualised 3-year return | +13.8% | +40.7% | +45.9% | +52.4% |
Risk & Volatility
Evenly matched — NUVL and ERAS each lead in 1 of 2 comparable metrics.
Risk & Volatility
ERAS is the less volatile stock with a 0.62 beta — it tends to amplify market swings less than AVBP's 1.16 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NUVL currently trades 93.2% from its 52-week high vs ERAS's 41.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.16x | 1.01x | 1.03x | 0.62x |
| 52-Week HighHighest price in past year | $32.14 | $113.02 | $103.00 | $24.28 |
| 52-Week LowLowest price in past year | $16.10 | $63.56 | $28.06 | $1.06 |
| % of 52W HighCurrent price vs 52-week peak | +91.8% | +93.2% | +83.6% | +41.7% |
| RSI (14)Momentum oscillator 0–100 | 52.3 | 48.9 | 50.5 | 35.8 |
| Avg Volume (50D)Average daily shares traded | 508K | 546K | 583K | 7.1M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: AVBP as "Buy", NUVL as "Buy", KYMR as "Buy", ERAS as "Buy". Consensus price targets imply 49.2% upside for AVBP (target: $44) vs 34.4% for ERAS (target: $14).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $44.00 | $144.40 | $118.06 | $13.60 |
| # AnalystsCovering analysts | 6 | 14 | 26 | 11 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
KYMR leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ERAS leads in 1 (Total Returns). 2 tied.
AVBP vs NUVL vs KYMR vs ERAS: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is AVBP or NUVL or KYMR or ERAS a better buy right now?
Analysts rate ArriVent BioPharma, Inc.
Common Stock (AVBP) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — AVBP or NUVL or KYMR or ERAS?
Over the past 5 years, Nuvalent, Inc.
(NUVL) delivered a total return of +461. 5%, compared to -41. 9% for Erasca, Inc. (ERAS). Over 10 years, the gap is even starker: NUVL returned +461. 5% versus ERAS's -41. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — AVBP or NUVL or KYMR or ERAS?
By beta (market sensitivity over 5 years), Erasca, Inc.
(ERAS) is the lower-risk stock at 0. 62β versus ArriVent BioPharma, Inc. Common Stock's 1. 16β — meaning AVBP is approximately 88% more volatile than ERAS relative to the S&P 500. On balance sheet safety, ArriVent BioPharma, Inc. Common Stock (AVBP) carries a lower debt/equity ratio of 0% versus 12% for Erasca, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — AVBP or NUVL or KYMR or ERAS?
On earnings-per-share growth, the picture is similar: Erasca, Inc.
grew EPS 16. 9% year-over-year, compared to -68. 8% for ArriVent BioPharma, Inc. Common Stock. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — AVBP or NUVL or KYMR or ERAS?
ArriVent BioPharma, Inc.
Common Stock (AVBP) is the more profitable company, earning 0. 0% net margin versus -794. 4% for Kymera Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: AVBP leads at 0. 0% versus -891. 3% for KYMR. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — AVBP or NUVL or KYMR or ERAS?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is AVBP or NUVL or KYMR or ERAS better for a retirement portfolio?
For long-horizon retirement investors, Erasca, Inc.
(ERAS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 62)). Both have compounded well over 10 years (ERAS: -41. 9%, AVBP: +47. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between AVBP and NUVL and KYMR and ERAS?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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